DaveManuel.com · Institutional Ownership · Who Owns It
ALNYLAM PHARMACEUTICALS INC (ALNY)
Institutional ownership reported to the SEC as of Q2 2026, across 32 quarters.
803
Reporting holders
$40.8B
Reported value
99.8%
Of shares outstanding
1.1%
Calls
0.5%
Puts
+2
Holder change
Institutions report 133,549,075 shares against 133,809,118 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. A figure this high can overstate: where an adviser and a sub-adviser both report the same shares, both are counted.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| FMR LLC | $4.5B | 15,023,962 | 0.20% | 31q | +3.1%+$133.9M |
| Capital World Investors | $3.4B | 11,144,846 | 0.40% | 31q | +3.2%+$103.1M |
| BlackRock, Inc. | $3.3B | 10,907,675 | 0.05% | 8q | +4.4%+$139.3M |
| Capital Research Global Investors | $2.9B | 9,750,699 | 0.41% | 15q | +3.0%+$84.1M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $2.0B | 6,538,390 | 0.09% | 2q | +0.7%+$14.2M |
| VANGUARD CAPITAL MANAGEMENT LLC | $1.8B | 6,029,478 | 0.04% | 2q | +1.4%+$24.9M |
| T. Rowe Price Investment Management, Inc. | $1.7B | 5,642,173 | 1.11% | 16q | +8.6%+$135.1M |
| Invesco Ltd. | $1.1B | 3,754,318 | 0.09% | 31q | -7.9%-$96.6M |
| STATE STREET CORP | $1.1B | 3,555,689 | 0.03% | 31q | +7.0%+$70.1M |
| GEODE CAPITAL MANAGEMENT, LLC | $791.3M | 2,635,840 | 0.04% | 31q | -0.9%-$7.4M |
| JPMORGAN CHASE & CO | $785.3M | 2,675,517 | 0.04% | 31q | -57.7%-$1.1B |
| BAILLIE GIFFORD & CO | $734.5M | 2,439,889 | 0.67% | 31q | -2.2%-$16.2M |
| NORGES BANK | $683.9M | 2,271,813 | 0.07% | 32q | +0.8%+$5.7M |
| WELLINGTON MANAGEMENT GROUP LLP | $635.3M | 2,110,407 | 0.11% | 31q | +9.0%+$52.5M |
| Orbis Allan Gray Ltd | $598.3M | 1,987,407 | 2.06% | 9q | +48.9%+$196.4M |
| Dodge & Cox | $588.6M | 1,955,393 | 0.31% | 31q | +1.4%+$7.9M |
| TWO SIGMA INVESTMENTS, LP | $564.7M | 1,875,937 | 0.41% | 10q | -5.9%-$35.1M |
| AMERICAN CENTURY COMPANIES INC | $558.1M | 1,853,956 | 0.25% | 31q | +2.9%+$15.5M |
| D. E. Shaw & Co., Inc. | $461.9M incl. $129.5M options CALL | 1,104,109 | 0.22% | 31q | +4.3%+$18.8M |
| Clearbridge Investments, LLC | $379.1M | 1,259,483 | 0.31% | 6q | -7.1%-$29.1M |
| PRICE T ROWE ASSOCIATES INC /MD/ | $345.9M | 1,149,201 | 0.03% | 31q | -19.8%-$85.4M |
| MORGAN STANLEY | $310.7M | 1,032,150 | 0.02% | 35q | +2.9%+$8.9M |
| BANK OF AMERICA CORP /DE/ | $299.4M | 994,476 | 0.02% | 31q | +2.9%+$8.3M |
| Legal & General Group Plc | $278.3M | 924,561 | 0.06% | 31q | -1.1%-$3.1M |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $269.1M | 893,795 | 0.21% | 31q | +34.9%+$69.7M |
| ROYAL BANK OF CANADA | $268.2M incl. $4.5M options PUT | 875,859 | 0.04% | 31q | +10.7%+$25.8M |
| NORTHERN TRUST CORP | $267.0M | 886,900 | 0.03% | 31q | +3.4%+$8.7M |
| VANGUARD FIDUCIARY TRUST CO | $259.7M | 862,782 | 0.06% | 2q | +2.6%+$6.6M |
| DEUTSCHE BANK AG\ | $248.6M incl. $3.1M options PUT | 815,400 | 0.07% | 34q | +7.1%+$16.4M |
| Deep Track Capital, LP | $248.3M | 825,000 | 3.61% | new | NEW |
| Qube Research & Technologies Ltd | $240.4M | 798,715 | 0.22% | 4q | -4.7%-$11.9M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $240.3M incl. $151.6M options CALL+PUT | 294,460 | 0.02% | 31q | +69.0%+$98.1M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $227.4M | 755,377 | 0.03% | 31q | +12.2%+$24.7M |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $219.6M | 729,635 | 0.81% | 11q | +726.5%+$193.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $219.1M | 727,848 | 0.04% | 31q | +7.4%+$15.2M |
| AQR CAPITAL MANAGEMENT LLC | $219.0M | 728,039 | 0.08% | 14q | -20.3%-$55.7M |
| FEDERATED HERMES, INC. | $216.7M | 719,905 | 0.31% | 11q | +4.7%+$9.7M |
| WELLS FARGO & COMPANY/MN | $204.7M incl. $111.4M options CALL | 310,047 | 0.03% | 31q | -9.5%-$21.6M |
| UBS Group AG | $188.7M | 627,004 | 0.02% | 31q | +36.6%+$50.6M |
| Amundi | $185.9M | 617,471 | 0.04% | 21q | -17.4%-$39.2M |
| LOOMIS SAYLES & CO L P | $174.7M | 580,187 | 0.22% | 21q | +13.3%+$20.5M |
| GOLDMAN SACHS GROUP INC | $173.0M | 574,757 | 0.02% | 31q | +22.4%+$31.7M |
| Bank of New York Mellon Corp | $148.1M | 492,071 | 0.02% | 31q | HELD |
| Polar Capital Holdings Plc | $145.3M | 482,751 | 0.34% | 23q | +87.3%+$67.8M |
| Paradigm Biocapital Advisors LP | $144.5M | 480,000 | 2.71% | new | NEW |
| FRANKLIN RESOURCES INC | $134.8M | 447,699 | 0.03% | 30q | -4.8%-$6.8M |
| FIRST TRUST ADVISORS LP | $126.9M | 421,534 | 0.07% | 31q | +10.1%+$11.7M |
| RAYMOND JAMES FINANCIAL INC | $118.2M | 392,799 | 0.03% | 7q | -3.5%-$4.3M |
| DIMENSIONAL FUND ADVISORS LP | $118.0M | 392,022 | 0.02% | 31q | +2.0%+$2.4M |
| MILLENNIUM MANAGEMENT LLC | $114.2M incl. $19.0M options CALL+PUT | 316,001 | 0.04% | 29q | -29.4%-$47.6M |
| Swiss National Bank | $112.6M | 374,080 | 0.06% | 31q | -3.5%-$4.1M |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $105.5M | 350,560 | 0.03% | 4q | -29.3%-$43.8M |
| CANADA PENSION PLAN INVESTMENT BOARD | $100.6M | 334,246 | 0.06% | 31q | +60.0%+$37.7M |
| Sumitomo Mitsui Trust Group, Inc. | $97.9M | 325,379 | 0.06% | 31q | +3.5%+$3.3M |
| Nuveen, LLC | $95.0M | 315,630 | 0.02% | 6q | -2.0%-$2.0M |
| CITADEL ADVISORS LLC | $94.9M incl. $37.4M options CALL+PUT | 191,029 | 0.01% | 31q | +715.8%+$83.2M |
| Candriam S.C.A. | $94.6M | 314,512 | 0.43% | 31q | +40.2%+$27.1M |
| Assenagon Asset Management S.A. | $93.7M | 311,390 | 0.06% | 16q | +141.6%+$54.9M |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $90.4M | 300,193 | 0.14% | 3q | +15.9%+$12.4M |
| CITIGROUP INC | $84.8M incl. $16.2M options CALL+PUT | 227,786 | 0.03% | 31q | -13.5%-$13.2M |
| Pictet Asset Management Holding SA | $83.3M | 278,613 | 0.08% | 12q | +17.1%+$12.2M |
| BNP PARIBAS FINANCIAL MARKETS | $81.6M | 271,023 | 0.03% | 31q | -3.5%-$3.0M |
| GILDER GAGNON HOWE & CO LLC | $81.0M | 269,051 | 0.84% | 31q | -3.9%-$3.3M |
| CONGRESS ASSET MANAGEMENT CO | $80.0M | 265,701 | 0.49% | 4q | -7.0%-$6.0M |
| MARSHALL WACE, LLP | $78.2M | 259,799 | 0.06% | 8q | -76.4%-$252.7M |
| Squarepoint Ops LLC | $77.6M incl. $7.2M options CALL | 233,999 | 0.09% | 18q | -45.2%-$63.9M |
| VANGUARD ASSET MANAGEMENT, Ltd | $77.6M | 257,710 | 0.05% | 2q | +17.5%+$11.6M |
| California Public Employees Retirement System | $76.5M | 254,053 | 0.04% | 31q | +11.4%+$7.8M |
| WESTFIELD CAPITAL MANAGEMENT CO LP | $76.0M | 252,383 | 0.25% | 7q | +2.8%+$2.1M |
| Korea Investment CORP | $74.6M | 247,660 | 0.14% | 26q | +23.6%+$14.3M |
| Woodline Partners LP | $74.1M | 246,282 | 0.23% | 6q | +1.0%+$722.2K |
| TD Asset Management Inc | $70.3M | 233,696 | 0.06% | 31q | -17.1%-$14.5M |
| HSBC HOLDINGS PLC | $70.3M incl. $35.8M options PUT | 115,279 | 0.03% | 31q | +28.6%+$15.7M |
| ROYAL LONDON ASSET MANAGEMENT LTD | $64.3M | 213,589 | 0.12% | 32q | -0.7%-$447.3K |
| AMERIPRISE FINANCIAL INC | $61.6M | 204,601 | 0.01% | 31q | -14.7%-$10.6M |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $60.2M | 199,861 | 0.06% | 31q | +1.5%+$902.5K |
| National Pension Service | $59.7M | 198,295 | 0.04% | 25q | +7.9%+$4.4M |
| PINEBRIDGE INVESTMENTS LLC | $58.9M | 195,709 | 0.49% | 3q | -27.9%-$22.8M |
| Robeco Institutional Asset Management B.V. | $56.6M | 188,084 | 0.07% | 19q | +48.7%+$18.5M |
| VICTORY CAPITAL MANAGEMENT INC | $52.0M | 172,842 | 0.03% | 28q | -11.8%-$7.0M |
| Man Group plc | $51.4M | 170,907 | 0.08% | 18q | -26.5%-$18.5M |
| Mitsubishi UFJ Asset Management Co., Ltd. | $50.8M | 168,664 | 0.03% | 31q | +10.8%+$5.0M |
| RHUMBLINE ADVISERS | $49.8M | 165,579 | 0.04% | 31q | -15.2%-$8.9M |
| Life Cycle Investment Partners Ltd | $49.8M | 165,424 | 0.23% | 3q | -6.8%-$3.6M |
| CIBC Bancorp USA Inc. | $49.3M | 163,733 | 0.06% | 3q | -3.1%-$1.6M |
| ANTIPODES PARTNERS Ltd | $49.2M | 163,533 | 0.90% | 15q | +12.5%+$5.5M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $48.6M | 161,773 | 0.05% | 26q | -10.1%-$5.5M |
| BARCLAYS PLC | $48.0M incl. $7.2M options CALL+PUT | 135,518 | 0.01% | 31q | -38.6%-$30.2M |
| Russell Investments Group, Ltd. | $47.5M | 158,228 | 0.04% | 31q | +7.2%+$3.2M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $47.2M | 157,223 | 0.07% | 7q | +12.5%+$5.3M |
| CAPITAL FUND MANAGEMENT S.A. | $46.9M | 155,904 | 0.21% | 3q | +11.3%+$4.8M |
| Vinva Investment Management Ltd | $45.5M | 154,972 | 0.30% | 4q | +323.4%+$34.7M |
| Hudson Bay Capital Management LP | $44.8M | 148,720 | 0.12% | 12q | +271.8%+$32.7M |
| 683 Capital Management, LLC | $42.9M incl. $32.4M options PUT | 35,000 | 2.11% | 10q | +66.7%+$17.2M |
| LMR Partners LLP | $42.6M incl. $2.2M options CALL | 134,214 | 0.16% | 3q | +79.8%+$18.9M |
| ENVESTNET ASSET MANAGEMENT INC | $41.1M | 136,395 | 0.01% | 26q | -20.6%-$10.7M |
| Jupiter Topco LLC | $40.8M | 135,545 | 0.02% | new | FIRST |
| ProShare Advisors LLC | $38.7M | 128,514 | 0.06% | 31q | -26.1%-$13.7M |
| DekaBank Deutsche Girozentrale | $37.3M | 113,193 | 0.06% | 31q | HELD |
| SEI INVESTMENTS CO | $36.7M | 121,960 | 0.03% | 31q | +21.6%+$6.5M |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-10-30 | 13G | Vanguard Portfolio Management | 5.0% |
What the insiders did
Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.
Officers and directors
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-06-01 | PYOTT DAVID E I | Director | Sold | 3,830 | $1.1M ×5 |
| 2026-10-02 | SUPRAN BRYAN | EVP, CLO and Secretary | Sold | 1,758 | $398.9K |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 193 | $439.9M | 1,723,629 | 25 | 67 | 60 | 3.3% |
| Q2 2026 | 803 | $40.8B | 133,549,075 | 82 | 314 | 272 | 1.6% |
| Q1 2026 | 801 | $44.0B | 131,405,200 | 93 | 311 | 256 | 1.5% |
| Q4 2025 | 861 | $54.7B | 134,074,544 | 124 | 284 | 281 | 2.3% |
| Q3 2025 | 833 | $62.5B | 134,417,341 | 222 | 274 | 215 | 2.0% |
| Q2 2025 | 664 | $43.6B | 132,505,386 | 91 | 256 | 211 | 0.9% |
| Q1 2025 | 639 | $35.4B | 129,456,430 | 102 | 227 | 198 | 1.4% |
| Q4 2024 | 603 | $30.4B | 127,779,312 | 65 | 230 | 172 | 1.2% |
| Q3 2024 | 577 | $35.3B | 125,977,349 | 100 | 214 | 163 | 1.9% |
| Q2 2024 | 538 | $30.9B | 121,770,307 | 86 | 184 | 165 | 4.3% |
| Q1 2024 | 512 | $18.4B | 117,912,759 | 69 | 196 | 148 | 4.3% |
| Q4 2023 | 506 | $23.8B | 121,072,067 | 75 | 159 | 150 | 2.5% |
| Q3 2023 | 463 | $21.3B | 117,915,141 | 42 | 147 | 159 | 1.8% |
| Q2 2023 | 478 | $22.9B | 118,807,924 | 47 | 158 | 151 | 1.2% |
| Q1 2023 | 480 | $27.0B | 133,043,566 | 49 | 172 | 158 | 1.3% |
| Q4 2022 | 491 | $29.2B | 120,038,468 | 73 | 158 | 160 | 2.5% |
| Q3 2022 | 480 | $42.3B | 206,922,835 | 113 | 147 | 145 | 1.3% |
| Q2 2022 | 418 | $40.7B | 273,484,842 | 51 | 120 | 155 | 2.1% |
| Q1 2022 | 438 | $34.2B | 206,863,745 | 67 | 143 | 144 | 1.0% |
| Q4 2021 | 428 | $40.7B | 236,681,616 | 56 | 150 | 121 | 1.5% |
| Q3 2021 | 400 | $41.7B | 220,975,256 | 45 | 139 | 116 | 1.0% |
| Q2 2021 | 400 | $38.1B | 222,312,313 | 57 | 129 | 120 | 1.4% |
| Q1 2021 | 384 | $35.7B | 254,040,761 | 49 | 141 | 114 | 0.4% |
| Q4 2020 | 370 | $17.0B | 128,678,288 | 38 | 117 | 120 | 1.8% |
| Q3 2020 | 358 | $36.0B | 245,827,477 | 30 | 118 | 125 | 0.7% |
| Q2 2020 | 376 | $41.2B | 276,214,330 | 74 | 131 | 107 | 0.7% |
| Q1 2020 | 335 | $22.8B | 206,321,916 | 54 | 117 | 95 | 1.3% |
| Q4 2019 | 318 | $33.4B | 285,458,315 | 58 | 87 | 98 | 0.9% |
| Q3 2019 | 282 | $77.0B | 954,865,179 | 37 | 103 | 74 | 0.2% |
| Q2 2019 | 290 | $69.7B | 959,900,662 | 39 | 111 | 69 | 0.3% |
| Q1 2019 | 293 | $19.7B | 211,305,381 | 38 | 103 | 86 | 0.7% |
| Q4 2018 | 281 | $15.2B | 209,650,039 | 3 | 9 | 6 | 1.2% |