DaveManuel.com · Institutional Ownership · Who Owns It
ANAPTYSBIO INC (ANAB)
Institutional ownership reported to the SEC as of Q2 2026, across 32 quarters.
214
Reporting holders
$2.0B
Reported value
0.2%
Calls
0.3%
Puts
+6
Holder change
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| EcoR1 Capital, LLC | $531.9M | 7,880,094 | 25.86% | 27q | HELD |
| BlackRock, Inc. | $124.5M | 1,844,049 | 0.00% | 8q | +9.7%+$11.0M |
| TANG CAPITAL MANAGEMENT LLC | $89.8M | 1,330,879 | 4.08% | 27q | HELD |
| STATE STREET CORP | $86.8M | 1,286,194 | 0.00% | 31q | +29.6%+$19.8M |
| VANGUARD CAPITAL MANAGEMENT LLC | $61.2M | 906,233 | 0.00% | 2q | +6.2%+$3.6M |
| Affinity Asset Advisors, LLC | $55.8M | 826,109 | 2.52% | 3q | -12.1%-$7.7M |
| MILLENNIUM MANAGEMENT LLC | $55.5M incl. $1.0M options CALL | 807,316 | 0.02% | 17q | +69.8%+$22.8M |
| Sanofi | $55.5M | 821,917 | 10.39% | 7q | HELD |
| Woodline Partners LP | $48.4M | 717,014 | 0.15% | 22q | +108.3%+$25.2M |
| 683 Capital Management, LLC | $44.6M | 660,000 | 2.19% | 6q | +5.6%+$2.4M |
| GEODE CAPITAL MANAGEMENT, LLC | $43.1M | 637,873 | 0.00% | 31q | +22.6%+$7.9M |
| Palo Alto Investors LP | $40.7M | 603,489 | 5.63% | 24q | -5.4%-$2.3M |
| GOLDMAN SACHS GROUP INC | $39.4M | 584,070 | 0.00% | 31q | +75.5%+$17.0M |
| First Light Asset Management, LLC | $39.3M | 582,004 | 2.39% | 13q | +2.9%+$1.1M |
| D. E. Shaw & Co., Inc. | $36.4M | 539,666 | 0.02% | 27q | -6.8%-$2.7M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $35.6M | 527,858 | 0.00% | 2q | +1.5%+$539.2K |
| Apis Capital Advisors, LLC | $33.5M | 497,000 | 3.27% | 2q | +108.8%+$17.5M |
| Sofinnova Investments, Inc. | $33.3M | 493,536 | 1.72% | 7q | +98.8%+$16.6M |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $33.0M | 488,651 | 0.01% | 5q | -0.7%-$234.2K |
| Nuveen, LLC | $28.4M | 420,664 | 0.01% | 6q | +33.1%+$7.1M |
| BANK OF AMERICA CORP /DE/ | $28.2M | 417,812 | 0.00% | 31q | -16.6%-$5.6M |
| CITADEL ADVISORS LLC | $27.9M incl. $1.3M options CALL+PUT | 394,373 | 0.00% | 31q | +68.9%+$11.4M |
| FEDERATED HERMES, INC. | $26.4M | 391,667 | 0.04% | 31q | +7.6%+$1.9M |
| Squarepoint Ops LLC | $21.9M | 324,446 | 0.02% | 5q | +21.2%+$3.8M |
| TWO SIGMA INVESTMENTS, LP | $17.8M | 262,995 | 0.01% | 15q | -43.5%-$13.6M |
| FIRST TRUST ADVISORS LP | $17.5M | 258,989 | 0.01% | new | NEW |
| MORGAN STANLEY | $17.4M | 257,091 | 0.00% | 35q | -74.1%-$49.7M |
| Coppell Advisory Solutions LLC | $16.6M | 3,638? | 1.37% | new | |
| FMR LLC | $16.2M | 240,511 | 0.00% | 31q | -49.1%-$15.7M |
| Qube Research & Technologies Ltd | $15.4M | 228,777 | 0.01% | 3q | -10.2%-$1.8M |
| HSBC HOLDINGS PLC | $14.9M | 216,949 | 0.01% | 2q | +72.6%+$6.3M |
| Empowered Funds, LLC | $13.9M | 206,010 | 0.07% | new | NEW |
| NORTHERN TRUST CORP | $13.7M | 202,767 | 0.00% | 31q | +10.5%+$1.3M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $13.7M | 202,305 | 0.00% | 31q | +5.0%+$649.2K |
| Invesco Ltd. | $13.6M | 202,056 | 0.00% | 13q | +66.8%+$5.5M |
| DIMENSIONAL FUND ADVISORS LP | $12.5M | 185,444 | 0.00% | new | NEW |
| Greenhaven Road Investment Management, L.P. | $11.5M | 171,059 | 7.50% | new | NEW |
| VICTORY CAPITAL MANAGEMENT INC | $11.4M | 169,227 | 0.01% | 12q | +56.4%+$4.1M |
| MACKENZIE FINANCIAL CORP | $10.2M | 150,979 | 0.01% | 3q | +347.7%+$7.9M |
| UBS Group AG | $9.9M | 146,832 | 0.00% | 31q | +84.3%+$4.5M |
| VANGUARD FIDUCIARY TRUST CO | $9.9M | 146,724 | 0.00% | 2q | +8.6%+$785.8K |
| Connor, Clark & Lunn Investment Management Ltd. | $9.5M | 141,026 | 0.02% | 3q | -11.1%-$1.2M |
| Ensign Peak Advisors, Inc | $7.2M | 107,096 | 0.01% | 20q | -14.8%-$1.3M |
| FRANKLIN RESOURCES INC | $7.2M | 106,949 | 0.00% | 2q | +62.5%+$2.8M |
| CITIGROUP INC | $6.7M | 99,114 | 0.00% | 31q | +35.0%+$1.7M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $6.5M CALL+PUT | options only | 0.00% | 31q | OPTIONS |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $6.3M | 93,732 | 0.01% | 3q | HELD |
| PRUDENTIAL FINANCIAL INC | $5.8M | 85,932 | 0.01% | 2q | +34.2%+$1.5M |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | $5.7M | 83,942 | 0.00% | new | NEW |
| JPMORGAN CHASE & CO | $5.3M | 80,236 | 0.00% | 31q | +589.0%+$4.5M |
| Granahan Investment Management, LLC | $5.1M | 75,962 | 0.18% | 7q | +14.8%+$660.1K |
| Irenic Capital Management LP | $4.8M | 70,447 | 0.23% | new | NEW |
| Eversept Partners, LP | $4.7M | 69,983 | 0.25% | 3q | +158.3%+$2.9M |
| SG Americas Securities, LLC | $4.5M | 66,730 | 0.00% | 3q | +168.5%+$2.8M |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $4.2M | 62,336 | 0.02% | 14q | +117.8%+$2.3M |
| STATE OF WISCONSIN INVESTMENT BOARD | $4.2M | 61,753 | 0.01% | 3q | +123.6%+$2.3M |
| RENAISSANCE TECHNOLOGIES LLC | $3.9M | 58,300 | 0.01% | 14q | -35.9%-$2.2M |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | $3.9M | 57,555 | 0.02% | 4q | -27.1%-$1.4M |
| Bank of New York Mellon Corp | $3.8M | 56,401 | 0.00% | 31q | +10.3%+$356.8K |
| DEUTSCHE BANK AG\ | $3.2M | 46,884 | 0.00% | 34q | -9.9%-$347.9K |
| AQR CAPITAL MANAGEMENT LLC | $3.1M | 46,323 | 0.00% | 8q | +42.7%+$935.3K |
| MARSHALL WACE, LLP | $3.0M | 43,822 | 0.00% | 2q | -35.6%-$1.6M |
| Bleakley Financial Group, LLC | $2.9M | 42,761 | 0.04% | 5q | -0.8%-$24.2K |
| WELLINGTON MANAGEMENT GROUP LLP | $2.8M | 41,796 | 0.00% | 10q | -10.8%-$343.2K |
| WELLS FARGO & COMPANY/MN | $2.8M | 41,707 | 0.00% | 14q | +25.7%+$575.6K |
| HighMark Wealth Management LLC | $2.7M | 39,716 | 0.90% | 6q | -57.8%-$3.7M |
| CAPITAL FUND MANAGEMENT S.A. | $2.6M | 39,142 | 0.01% | new | NEW |
| Trexquant Investment LP | $2.4M | 35,404 | 0.01% | 12q | -58.4%-$3.4M |
| Atom Investors LP | $2.3M | 33,917 | 0.20% | new | NEW |
| PRICE T ROWE ASSOCIATES INC /MD/ | $2.2M | 32,374 | 0.00% | 12q | +9.0%+$181.2K |
| Swiss National Bank | $2.1M | 31,700 | 0.00% | 31q | +14.9%+$276.8K |
| Voleon Capital Management LP | $2.1M | 31,425 | 0.04% | new | NEW |
| Tidal Investments LLC | $2.1M | 31,270 | 0.00% | 2q | -14.0%-$343.0K |
| Tema ETFs LLC | $2.1M | 31,270 | 0.07% | 5q | +0.6%+$13.6K |
| Moody Aldrich Partners LLC | $2.1M | 30,926 | 0.38% | 6q | -21.6%-$575.7K |
| Aquatic Capital Management LLC | $2.1M | 30,813 | 0.07% | new | NEW |
| SummitTX Capital, L.P. | $1.9M | 28,779 | 0.05% | new | NEW |
| ALLIANCEBERNSTEIN L.P. | $1.8M | 32,820 | 0.00% | 31q | +4.8%+$83.2K |
| RHUMBLINE ADVISERS | $1.8M | 26,346 | 0.00% | 31q | +10.5%+$168.6K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $1.6M | 23,310 | 0.00% | 14q | -24.1%-$500.6K |
| BURNEY CO/ | $1.5M | 22,557 | 0.04% | new | NEW |
| Rafferty Asset Management, LLC | $1.5M | 21,864 | 0.00% | 10q | -19.8%-$363.5K |
| XTX Topco Ltd | $1.4M | 21,411 | 0.02% | 5q | -57.6%-$2.0M |
| HUSSMAN STRATEGIC ADVISORS, INC. | $1.4M | 21,000 | 0.33% | 2q | HELD |
| TUDOR INVESTMENT CORP ET AL | $1.4M | 20,019 | 0.00% | 8q | +303.4%+$1.0M |
| CREDIT AGRICOLE S A | $1.4M | 20,000 | 0.00% | 3q | HELD |
| MARTINGALE ASSET MANAGEMENT L P | $1.3M | 19,942 | 0.03% | 2q | -29.1%-$553.5K |
| Creative Planning | $1.3M | 18,773 | 0.00% | 6q | +11.5%+$130.7K |
| Y-Intercept (Hong Kong) Ltd | $1.2M | 18,468 | 0.02% | 3q | -18.6%-$285.7K |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $1.2M | 17,629 | 0.00% | 31q | +25.9%+$245.0K |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $1.2M | 17,536 | 0.00% | 5q | +12.0%+$126.4K |
| VIRGINIA RETIREMENT SYSTEMS ET Al | $1.2M | 17,250 | 0.01% | 3q | +7.5%+$81.0K |
| Diametric Capital, LP | $1.1M | 16,868 | 0.12% | new | NEW |
| CANADA PENSION PLAN INVESTMENT BOARD | $1.1M | 16,500 | 0.00% | 2q | +10.7%+$108.0K |
| Legal & General Group Plc | $1.1M | 16,415 | 0.00% | 31q | +18.7%+$174.4K |
| SIMPLEX TRADING, LLC | $1.1M incl. $1.0M options CALL+PUT | 1,267 | 0.00% | 8q | HELD |
| Russell Investments Group, Ltd. | $1.1M | 16,301 | 0.00% | 5q | +22.7%+$203.4K |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $1.1M | 15,870 | 0.00% | new | NEW |
| Cresset Asset Management, LLC | $972.8K | 14,412 | 0.00% | 6q | +3.9%+$36.7K |
| Vanguard Global Advisers, LLC | $939.5K | 13,919 | 0.00% | 2q | +18.4%+$146.1K |
Showing the largest 100 of 215 reported holders. The count of 214 above leaves out 1 position whose reported value failed our price check; it is listed here as filed.
What the insiders did
Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.
Officers and directors
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-10-01 | RENTON HOLLINGS | Director | Sold | 5,000 | $249.4K |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 33 | $14.4M | 286,413 | 7 | 13 | 4 | 0.0% |
| Q2 2026 | 214 | $2.0B | 30,128,513 | 44 | 72 | 65 | 0.5% |
| Q1 2026 | 208 | $1.6B | 28,251,890 | 44 | 56 | 65 | 0.1% |
| Q4 2025 | 182 | $1.5B | 29,406,986 | 35 | 50 | 63 | 3.1% |
| Q3 2025 | 167 | $1.0B | 31,685,630 | 34 | 41 | 56 | 2.4% |
| Q2 2025 | 149 | $824.4M | 36,765,744 | 27 | 42 | 50 | 1.0% |
| Q1 2025 | 154 | $755.4M | 40,052,703 | 43 | 41 | 41 | 1.4% |
| Q4 2024 | 143 | $524.2M | 35,417,710 | 18 | 48 | 35 | 10.6% |
| Q3 2024 | 165 | $1.2B | 33,662,668 | 46 | 61 | 30 | 5.5% |
| Q2 2024 | 133 | $748.4M | 29,807,578 | 23 | 40 | 45 | 0.2% |
| Q1 2024 | 133 | $689.9M | 30,506,574 | 25 | 36 | 39 | 0.4% |
| Q4 2023 | 119 | $662.2M | 30,798,492 | 14 | 32 | 40 | 0.4% |
| Q3 2023 | 116 | $548.4M | 30,419,401 | 14 | 32 | 35 | 0.4% |
| Q2 2023 | 116 | $617.3M | 30,230,772 | 13 | 38 | 36 | 0.4% |
| Q1 2023 | 113 | $684.5M | 31,330,479 | 16 | 33 | 35 | 0.4% |
| Q4 2022 | 116 | $1.0B | 32,875,117 | 12 | 31 | 38 | 0.2% |
| Q3 2022 | 106 | $863.2M | 33,594,269 | 7 | 33 | 34 | 0.7% |
| Q2 2022 | 121 | $4.4B | 214,796,909 | 18 | 35 | 38 | 0.1% |
| Q1 2022 | 126 | $3.6B | 144,906,736 | 14 | 29 | 47 | 0.0% |
| Q4 2021 | 133 | $7.5B | 215,816,024 | 24 | 32 | 39 | 0.0% |
| Q3 2021 | 123 | $3.0B | 111,176,272 | 15 | 28 | 40 | 0.0% |
| Q2 2021 | 117 | $997.3M | 38,315,897 | 14 | 24 | 50 | 0.4% |
| Q1 2021 | 119 | $804.1M | 49,774,065 | 13 | 38 | 38 | 1.9% |
| Q4 2020 | 130 | $2.7B | 125,428,387 | 24 | 35 | 43 | 0.2% |
| Q3 2020 | 126 | $551.9M | 37,330,455 | 22 | 26 | 49 | 0.2% |
| Q2 2020 | 117 | $950.0M | 42,359,964 | 25 | 28 | 45 | 0.4% |
| Q1 2020 | 112 | $723.9M | 50,808,420 | 16 | 41 | 37 | 0.8% |
| Q4 2019 | 120 | $627.0M | 37,396,956 | 37 | 47 | 18 | 3.1% |
| Q3 2019 | 119 | $1.3B | 37,140,898 | 17 | 48 | 29 | 2.9% |
| Q2 2019 | 126 | $2.6B | 44,801,569 | 24 | 59 | 20 | 1.5% |
| Q1 2019 | 126 | $3.2B | 43,435,161 | 25 | 49 | 26 | 0.9% |
| Q4 2018 | 119 | $2.8B | 43,551,780 | 3 | 3 | 2 | 0.7% |