DaveManuel.com · Institutional Ownership · Who Owns It
BIOCRYST PHARMACEUTICALS INC (BCRX)
Institutional ownership reported to the SEC as of Q2 2026, across 32 quarters.
320
Reporting holders
$2.7B
Reported value
103.3%
Of shares outstanding
1.2%
Calls
0.3%
Puts
+15
Holder change
Institutions report 263,847,035 shares against 255,535,105 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| BlackRock, Inc. | $238.9M | 23,893,036 | 0.00% | 8q | +5.5%+$12.4M |
| RA CAPITAL MANAGEMENT, L.P. | $158.3M | 15,827,186 | 1.38% | 3q | HELD |
| STATE STREET CORP | $151.9M | 15,191,098 | 0.00% | 31q | +24.4%+$29.8M |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $151.0M | 15,096,403 | 1.57% | 14q | HELD |
| VANGUARD CAPITAL MANAGEMENT LLC | $113.6M | 11,364,236 | 0.00% | 2q | +2.1%+$2.3M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $111.4M | 11,139,158 | 0.01% | 2q | -0.9%-$1.1M |
| TCG Crossover Management, LLC | $110.2M | 11,020,968 | 2.65% | 2q | HELD |
| PERCEPTIVE ADVISORS LLC | $103.1M | 10,308,888 | 1.55% | 3q | +38.7%+$28.7M |
| Jupiter Topco LLC | $95.3M | 9,540,764 | 0.04% | new | FIRST |
| Vestal Point Capital, LP | $83.0M | 8,300,000 | 1.94% | 3q | +18.1%+$12.8M |
| TWO SIGMA INVESTMENTS, LP | $67.8M | 6,775,349 | 0.05% | 31q | +6.0%+$3.8M |
| GEODE CAPITAL MANAGEMENT, LLC | $62.5M | 6,248,046 | 0.00% | 31q | +8.0%+$4.7M |
| Aberdeen Group plc | $53.1M | 5,310,871 | 0.07% | 3q | +5.4%+$2.7M |
| UBS Group AG | $50.8M | 5,078,280 | 0.01% | 31q | +2.7%+$1.3M |
| BANK OF AMERICA CORP /DE/ | $48.0M | 4,801,284 | 0.00% | 31q | -5.7%-$2.9M |
| GOLDMAN SACHS GROUP INC | $44.8M | 4,481,874 | 0.00% | 31q | +90.9%+$21.3M |
| Frazier Life Sciences Management, L.P. | $40.1M | 4,009,240 | 0.87% | 2q | HELD |
| Nuveen, LLC | $40.1M | 4,007,237 | 0.01% | 6q | +4.9%+$1.9M |
| JANE STREET GROUP, LLC | $38.2M incl. $10.5M options CALL+PUT | 2,762,683 | 0.00% | 29q | +343.7%+$29.6M |
| Nantahala Capital Management, LLC | $38.0M | 3,802,320 | 0.63% | 3q | +91.3%+$18.1M |
| MILLENNIUM MANAGEMENT LLC | $33.9M | 3,394,729 | 0.01% | 31q | +1708.4%+$32.1M |
| GW&K Investment Management, LLC | $31.7M | 3,171,113 | 0.25% | 16q | -2.1%-$693.5K |
| DIMENSIONAL FUND ADVISORS LP | $27.2M | 2,718,781 | 0.00% | 3q | +1.0%+$281.3K |
| Fisher Asset Management, LLC | $26.0M | 2,604,027 | 0.01% | 21q | -4.7%-$1.3M |
| RENAISSANCE TECHNOLOGIES LLC | $25.3M | 2,530,290 | 0.03% | 12q | +225.7%+$17.5M |
| Kynam Capital Management, LP | $25.2M | 2,522,660 | 1.39% | 14q | -55.6%-$31.6M |
| Candriam S.C.A. | $25.1M | 2,514,949 | 0.11% | 2q | +10.0%+$2.3M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $23.5M | 2,353,291 | 0.00% | 31q | HELD |
| RICE HALL JAMES & ASSOCIATES, LLC | $23.3M | 2,332,043 | 1.13% | 13q | +4.6%+$1.0M |
| NORTHERN TRUST CORP | $22.6M | 2,255,731 | 0.00% | 31q | +7.2%+$1.5M |
| AQR CAPITAL MANAGEMENT LLC | $22.1M | 2,214,302 | 0.01% | 31q | +403.1%+$17.7M |
| CITADEL ADVISORS LLC | $21.4M incl. $3.8M options CALL+PUT | 1,759,160 | 0.00% | 31q | +72.7%+$9.0M |
| MORGAN STANLEY | $20.0M | 1,999,684 | 0.00% | 35q | -1.2%-$233.0K |
| IMC-Chicago, LLC | $19.0M incl. $2.6M options CALL+PUT | 1,634,336 | 0.00% | 2q | +158.9%+$11.6M |
| Eversept Partners, LP | $18.7M | 1,865,653 | 0.97% | 15q | -38.6%-$11.7M |
| ORBIMED ADVISORS LLC | $18.5M | 1,852,000 | 0.34% | 4q | +29.9%+$4.3M |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | $18.4M | 1,844,912 | 0.03% | 2q | +50.4%+$6.2M |
| STIFEL FINANCIAL CORP | $18.3M | 1,826,234 | 0.02% | 26q | HELD |
| VANGUARD FIDUCIARY TRUST CO | $17.6M | 1,759,573 | 0.00% | 2q | +5.7%+$952.8K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $17.0M incl. $5.1M options CALL+PUT | 1,195,651 | 0.00% | 31q | -57.5%-$23.1M |
| JUPITER ASSET MANAGEMENT LTD | $16.4M | 1,642,874 | 0.08% | 8q | +37.3%+$4.5M |
| Parkman Healthcare Partners LLC | $16.2M | 1,624,279 | 1.66% | 9q | -4.9%-$838.2K |
| Legal & General Group Plc | $14.6M | 1,455,514 | 0.00% | 31q | +3.1%+$443.2K |
| OP Asset Management Ltd | $13.4M | 1,340,990 | 0.14% | 3q | +7.0%+$881.3K |
| Invesco Ltd. | $12.3M | 1,233,783 | 0.00% | 25q | -5.7%-$750.3K |
| Pictet Asset Management Holding SA | $12.0M | 1,249,771 | 0.01% | 12q | +165.0%+$7.4M |
| BNP PARIBAS FINANCIAL MARKETS | $11.7M | 1,174,052 | 0.00% | 31q | -9.8%-$1.3M |
| FIRST TRUST ADVISORS LP | $11.2M | 1,120,469 | 0.01% | 8q | +39.9%+$3.2M |
| HRT FINANCIAL LP | $10.8M | 1,081,523 | 0.02% | new | NEW |
| MOORE CAPITAL MANAGEMENT, LP | $8.5M | 848,336 | 0.13% | new | NEW |
| SIMPLEX TRADING, LLC | $8.1M incl. $7.8M options CALL+PUT | 36,794 | 0.00% | 2q | -31.8%-$3.8M |
| FMR LLC | $8.1M | 808,903 | 0.00% | 31q | +27.8%+$1.8M |
| ExodusPoint Capital Management, LP | $7.4M | 744,917 | 0.05% | 2q | +291.9%+$5.5M |
| Man Group plc | $7.3M | 732,867 | 0.01% | 8q | -43.3%-$5.6M |
| Rosalind Advisors, Inc. | $7.2M | 721,504 | 2.68% | 2q | -21.8%-$2.0M |
| Schonfeld Strategic Advisors LLC | $7.1M | 710,816 | 0.03% | 9q | -46.9%-$6.3M |
| Assenagon Asset Management S.A. | $7.1M | 706,088 | 0.00% | 22q | +203.1%+$4.7M |
| Bank of New York Mellon Corp | $6.8M | 680,481 | 0.00% | 31q | +6.7%+$428.2K |
| Jump Financial, LLC | $5.7M | 569,956 | 0.05% | 9q | +420.9%+$4.6M |
| JPMORGAN CHASE & CO | $5.7M incl. $548.2K options PUT | 525,449 | 0.00% | 31q | -65.9%-$11.0M |
| DEUTSCHE BANK AG\ | $5.6M | 563,361 | 0.00% | 34q | -31.4%-$2.6M |
| CITIGROUP INC | $5.5M incl. $1.9M options CALL+PUT | 360,189 | 0.00% | 31q | +406.1%+$4.4M |
| VOYA INVESTMENT MANAGEMENT LLC | $5.4M | 538,813 | 0.00% | 31q | HELD |
| Elmind Capital, LP | $5.2M | 520,000 | 1.31% | 3q | -48.0%-$4.8M |
| GROUP ONE TRADING LLC | $5.2M incl. $4.4M options CALL+PUT | 72,749 | 0.01% | 31q | -46.6%-$4.5M |
| Bridgewater Associates, LP | $4.9M | 491,057 | 0.02% | 4q | -23.0%-$1.5M |
| FRANKLIN RESOURCES INC | $4.8M | 480,364 | 0.00% | 10q | -8.2%-$429.2K |
| PRINCIPAL FINANCIAL GROUP INC | $4.7M | 468,785 | 0.00% | 31q | +8.9%+$382.3K |
| NAN FUNG TRINITY (HK) LTD | $4.5M | 450,000 | 0.44% | new | NEW |
| SPHERA FUNDS MANAGEMENT LTD. | $4.2M | 422,051 | 0.55% | 3q | -51.3%-$4.4M |
| Swiss National Bank | $4.2M | 415,268 | 0.00% | 31q | +1.6%+$66.0K |
| D. E. Shaw & Co., Inc. | $4.1M | 408,529 | 0.00% | 11q | +35.2%+$1.1M |
| Susquehanna Portfolio Strategies, LLC | $4.0M | 404,704 | 0.06% | 3q | +8.2%+$306.9K |
| DAFNA Capital Management LLC | $4.0M | 400,248 | 0.76% | 15q | -7.0%-$300.0K |
| Hudson Bay Capital Management LP | $4.0M | 400,000 | 0.01% | 3q | -18.4%-$903.7K |
| WEDGE CAPITAL MANAGEMENT L L P/NC | $3.8M | 380,801 | 0.06% | new | NEW |
| DOLIVER ADVISORS, LP | $3.7M | 374,328 | 0.85% | 20q | HELD |
| Aquatic Capital Management LLC | $3.6M | 362,895 | 0.12% | new | NEW |
| MACKENZIE FINANCIAL CORP | $3.5M | 347,299 | 0.00% | 18q | +42.7%+$1.0M |
| Phocas Financial Corp. | $3.4M | 340,541 | 0.47% | 3q | +74.2%+$1.5M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $3.2M | 320,566 | 0.00% | 31q | -13.1%-$484.1K |
| ALPS ADVISORS INC | $3.2M | 317,960 | 0.01% | 2q | +427.7%+$2.6M |
| ALLIANCEBERNSTEIN L.P. | $3.1M | 327,909 | 0.00% | 31q | +24.4%+$611.6K |
| PRICE T ROWE ASSOCIATES INC /MD/ | $3.1M | 305,897 | 0.00% | 27q | +32.4%+$749.0K |
| WELLINGTON MANAGEMENT GROUP LLP | $2.9M | 293,925 | 0.00% | 8q | +197.2%+$2.0M |
| TUDOR INVESTMENT CORP ET AL | $2.9M incl. $899.0K options CALL | 195,128 | 0.00% | 7q | HELD |
| RHUMBLINE ADVISERS | $2.8M | 279,839 | 0.00% | 31q | +5.1%+$137.0K |
| NFJ INVESTMENT GROUP, LLC | $2.8M | 278,792 | 0.09% | new | NEW |
| Rafferty Asset Management, LLC | $2.7M | 265,618 | 0.01% | 30q | -25.0%-$886.4K |
| Point72 Asset Management, L.P. | $2.6M | 260,917 | 0.00% | new | NEW |
| WINTON GROUP Ltd | $2.6M | 255,600 | 0.08% | 3q | +380.3%+$2.0M |
| MARSHALL WACE, LLP | $2.5M | 252,764 | 0.00% | 2q | +2.6%+$62.9K |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $2.5M | 251,230 | 0.00% | 31q | -2.8%-$71.2K |
| MARTINGALE ASSET MANAGEMENT L P | $2.4M | 242,508 | 0.06% | 2q | +329.0%+$1.9M |
| IEQ CAPITAL, LLC | $2.3M | 227,421 | 0.01% | new | NEW |
| WELLS FARGO & COMPANY/MN | $2.2M | 222,894 | 0.00% | 31q | -5.9%-$140.5K |
| HUSSMAN STRATEGIC ADVISORS, INC. | $2.1M | 210,000 | 0.48% | new | NEW |
| PFM Health Sciences, LP | $2.1M | 207,357 | 0.18% | new | NEW |
| VANGUARD ASSET MANAGEMENT, Ltd | $2.0M | 196,280 | 0.00% | 2q | HELD |
| Engineers Gate Manager LP | $1.8M | 175,002 | 0.02% | 14q | -10.0%-$194.7K |
Showing the largest 100 of 320 reported holders.
What the company announced
Form 8-K filings from the last 120 days, showing only the items worth a reader's attention. Earnings releases, exhibit attachments and general disclosures are filed constantly and are left out. Filed is when the SEC received it; event is the date the company says the thing happened.
| Filed | Event date | What | Source |
|---|---|---|---|
| 2026-08-04 | 2026-06-25 | Exit or disposal costs | filing |
What the insiders did
Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.
Officers and directors
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-05-13 | Barnes Alane P | Chief Legal Officer | Sold | 62,500 | $596.2K |
| 2026-05-18 | McKee Amy E | Director | Sold | 11,180 | $100.3K |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 55 | $20.9M | 2,508,626 | 5 | 18 | 16 | 0.0% |
| Q2 2026 | 320 | $2.7B | 263,847,035 | 55 | 127 | 86 | 1.5% |
| Q1 2026 | 305 | $2.4B | 249,294,740 | 69 | 114 | 76 | 0.8% |
| Q4 2025 | 275 | $1.7B | 212,620,364 | 45 | 85 | 95 | 1.2% |
| Q3 2025 | 285 | $1.5B | 195,336,188 | 35 | 90 | 99 | 0.8% |
| Q2 2025 | 297 | $1.8B | 197,431,963 | 51 | 110 | 82 | 1.1% |
| Q1 2025 | 276 | $1.3B | 175,261,251 | 38 | 107 | 69 | 1.1% |
| Q4 2024 | 260 | $1.3B | 167,871,739 | 21 | 74 | 86 | 1.6% |
| Q3 2024 | 261 | $1.3B | 173,916,806 | 49 | 78 | 74 | 1.4% |
| Q2 2024 | 243 | $1.1B | 175,218,662 | 38 | 81 | 68 | 1.6% |
| Q1 2024 | 239 | $964.6M | 186,418,708 | 31 | 80 | 67 | 1.8% |
| Q4 2023 | 236 | $1.1B | 180,584,059 | 24 | 80 | 70 | 2.8% |
| Q3 2023 | 233 | $1.3B | 175,835,548 | 19 | 98 | 51 | 2.2% |
| Q2 2023 | 239 | $1.2B | 174,093,090 | 24 | 96 | 55 | 1.9% |
| Q1 2023 | 241 | $1.5B | 173,906,762 | 38 | 88 | 69 | 2.3% |
| Q4 2022 | 231 | $2.1B | 180,508,160 | 37 | 83 | 65 | 3.5% |
| Q3 2022 | 223 | $3.9B | 307,617,036 | 41 | 64 | 53 | 1.8% |
| Q2 2022 | 208 | $3.9B | 362,778,160 | 43 | 63 | 56 | 2.0% |
| Q1 2022 | 223 | $5.0B | 297,615,580 | 44 | 58 | 69 | 2.6% |
| Q4 2021 | 198 | $5.4B | 377,109,826 | 26 | 66 | 50 | 3.0% |
| Q3 2021 | 193 | $4.8B | 324,585,071 | 32 | 63 | 60 | 3.0% |
| Q2 2021 | 190 | $5.2B | 317,252,985 | 41 | 56 | 57 | 2.9% |
| Q1 2021 | 188 | $3.4B | 332,291,599 | 45 | 50 | 67 | 1.8% |
| Q4 2020 | 175 | $6.1B | 817,834,956 | 31 | 54 | 52 | 0.5% |
| Q3 2020 | 151 | $4.6B | 1,327,988,333 | 25 | 58 | 45 | 0.2% |
| Q2 2020 | 165 | $24.0B | 5,035,048,437 | 53 | 52 | 37 | 0.1% |
| Q1 2020 | 133 | $15.5B | 7,746,925,073 | 24 | 49 | 36 | 0.0% |
| Q4 2019 | 132 | $17.6B | 5,088,843,917 | 34 | 53 | 23 | 0.0% |
| Q3 2019 | 111 | $2.3B | 789,392,074 | 16 | 34 | 34 | 0.1% |
| Q2 2019 | 112 | $2.2B | 479,988,095 | 17 | 41 | 28 | 18.1% |
| Q1 2019 | 131 | $4.5B | 550,725,882 | 24 | 47 | 23 | 0.3% |
| Q4 2018 | 120 | $2.4B | 303,100,880 | 3 | 2 | 4 | 0.1% |