CRESCENT BIOPHARMA INC. (CBIO)
Institutional ownership reported to the SEC as of Q2 2026, across 32 quarters.
Institutions report 29,586,731 shares against 37,143,940 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| FMR LLC | $74.4M | 4,133,514 | 0.00% | 5q | HELD |
| BVF INC/IL | $49.5M | 2,748,763 | 1.27% | 5q | HELD |
| Fairmount Funds Management LLC | $49.5M | 2,747,866 | 3.27% | 5q | HELD |
| Venrock Adviser, LLC | $38.4M | 2,133,576 | 1.16% | 5q | HELD |
| Logos Global Management LP | $34.2M | 1,900,000 | 1.47% | 5q | +293.8%+$25.5M |
| FCPM III SERVICES B.V. | $30.2M | 1,677,852 | 4.02% | 3q | HELD |
| Balyasny Asset Management L.P. | $29.9M | 1,662,917 | 0.04% | 3q | +10.1%+$2.8M |
| Vestal Point Capital, LP | $29.3M | 1,630,000 | 0.69% | 3q | +8.7%+$2.3M |
| Opaleye Management Inc. | $23.7M | 1,319,351 | 2.15% | 3q | +0.5%+$121.2K |
| BlackRock, Inc. | $22.9M | 1,271,762 | 0.00% | 5q | +999.0%+$20.8M |
| TANG CAPITAL MANAGEMENT LLC | $20.9M | 1,160,000 | 0.95% | 5q | HELD |
| VANGUARD CAPITAL MANAGEMENT LLC | $13.8M | 767,755 | 0.00% | 2q | -4.2%-$605.5K |
| Boxer Capital Management, LLC | $8.2M | 453,686 | 0.62% | 2q | HELD |
| MILLENNIUM MANAGEMENT LLC | $7.3M | 403,859 | 0.00% | 3q | +24.8%+$1.4M |
| GEODE CAPITAL MANAGEMENT, LLC | $6.9M | 384,576 | 0.00% | 4q | +269.0%+$5.0M |
| JENNISON ASSOCIATES LLC | $6.8M | 378,507 | 0.00% | 2q | +147.4%+$4.1M |
| RTW INVESTMENTS, LP | $6.7M | 372,856 | 0.06% | 3q | HELD |
| NEXTBio Capital Management LP | $6.7M | 372,856 | 3.09% | 3q | HELD |
| Remedium Capital Partners, LLC | $6.5M | 361,250 | 1.44% | new | NEW |
| STATE STREET CORP | $5.7M | 315,587 | 0.00% | 4q | +707.8%+$5.0M |
| AMERIPRISE FINANCIAL INC | $5.4M | 302,568 | 0.00% | new | NEW |
| Point72 Asset Management, L.P. | $5.4M | 300,000 | 0.01% | 3q | HELD |
| PRICE T ROWE ASSOCIATES INC /MD/ | $5.0M | 275,581 | 0.00% | 4q | -9.2%-$503.5K |
| MARSHALL WACE, LLP | $3.9M | 214,300 | 0.00% | 4q | +6.7%+$243.4K |
| PERCEPTIVE ADVISORS LLC | $3.7M | 206,942 | 0.06% | 5q | HELD |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $3.4M | 188,803 | 0.00% | new | NEW |
| TWO SIGMA INVESTMENTS, LP | $3.4M | 186,874 | 0.00% | 4q | +61.3%+$1.3M |
| STEMPOINT CAPITAL LP | $3.3M | 182,382 | 0.57% | new | NEW |
| UBS Group AG | $3.2M | 175,182 | 0.00% | 5q | +111.8%+$1.7M |
| NORTHERN TRUST CORP | $2.5M | 138,778 | 0.00% | 4q | +705.5%+$2.2M |
| Exome Asset Management LLC | $2.3M | 127,769 | 1.42% | 2q | -16.6%-$457.6K |
| SECTORAL ASSET MANAGEMENT INC | $2.2M | 121,300 | 1.52% | new | NEW |
| Woodline Partners LP | $1.7M | 94,488 | 0.01% | 3q | +27.7%+$368.8K |
| VANGUARD FIDUCIARY TRUST CO | $1.4M | 75,225 | 0.00% | 2q | +52.2%+$464.4K |
| Burkehill Global Management, LP | $1.3M | 74,000 | 0.05% | 3q | HELD |
| Blackstone Inc. | $1.1M | 62,647 | 0.00% | new | NEW |
| SILVERARC CAPITAL MANAGEMENT, LLC | $1.1M | 59,104 | 0.11% | 2q | -54.7%-$1.3M |
| Y-Intercept (Hong Kong) Ltd | $914.8K | 50,824 | 0.02% | new | NEW |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $904.6K | 50,258 | 0.00% | new | NEW |
| Nuveen, LLC | $857.3K | 47,629 | 0.00% | new | NEW |
| Bank of New York Mellon Corp | $824.0K | 45,778 | 0.00% | new | NEW |
| Stonepine Capital Management, LLC | $720.0K | 40,000 | 0.41% | 3q | -52.9%-$810.0K |
| BANK OF AMERICA CORP /DE/ | $464.8K | 25,821 | 0.00% | 5q | -11.8%-$62.2K |
| RHUMBLINE ADVISERS | $458.8K | 25,487 | 0.00% | new | NEW |
| MOORE CAPITAL MANAGEMENT, LP | $450.0K | 25,000 | 0.01% | 3q | HELD |
| Squarepoint Ops LLC | $435.0K | 24,166 | 0.00% | new | NEW |
| AMERICAN CENTURY COMPANIES INC | $410.5K | 22,805 | 0.00% | new | NEW |
| WELLS FARGO & COMPANY/MN | $354.6K | 19,700 | 0.00% | new | NEW |
| Quadrature Capital Ltd | $346.1K | 19,227 | 0.00% | 3q | -8.1%-$30.4K |
| ADAR1 Capital Management, LLC | $328.9K | 18,275 | 0.02% | 3q | -63.6%-$576.0K |
| Virtus Investment Advisers, LLC | $328.6K | 18,258 | 0.08% | new | NEW |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $319.6K | 17,755 | 0.00% | 4q | -28.7%-$128.7K |
| MORGAN STANLEY | $318.6K | 17,698 | 0.00% | 5q | -4.7%-$15.8K |
| WELLINGTON MANAGEMENT GROUP LLP | $262.8K | 14,600 | 0.00% | new | NEW |
| BANK OF MONTREAL /CAN/ | $247.8K | 13,768 | 0.00% | new | NEW |
| MetLife Investment Management, LLC | $230.0K | 12,780 | 0.00% | new | NEW |
| Invesco Ltd. | $211.2K | 11,731 | 0.00% | new | NEW |
| Persistent Asset Partners Ltd | $197.4K | 10,968 | 0.06% | new | NEW |
| XTX Topco Ltd | $190.2K | 10,564 | 0.00% | new | NEW |
| CITIGROUP INC | $182.5K | 10,141 | 0.00% | 4q | -49.7%-$180.5K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $178.2K | 9,901 | 0.00% | new | NEW |
| JPMORGAN CHASE & CO | $162.4K | 9,020 | 0.00% | 4q | -78.0%-$575.7K |
| NEW YORK STATE COMMON RETIREMENT FUND | $136.8K | 7,600 | 0.00% | new | NEW |
| Police & Firemen's Retirement System of New Jersey | $114.6K | 6,369 | 0.00% | new | NEW |
| BARCLAYS PLC | $80.3K | 4,462 | 0.00% | 2q | -85.2%-$463.1K |
| BNP PARIBAS FINANCIAL MARKETS | $59.5K | 3,303 | 0.00% | 5q | -79.0%-$223.0K |
| Vanguard Global Advisers, LLC | $48.9K | 2,714 | 0.00% | 2q | -21.8%-$13.6K |
| Legal & General Group Plc | $37.7K | 2,097 | 0.00% | new | NEW |
| Tower Research Capital LLC (TRC) | $31.7K | 1,761 | 0.00% | new | NEW |
| Russell Investments Group, Ltd. | $31.1K | 1,726 | 0.00% | new | NEW |
| ROYAL BANK OF CANADA | $12.0K | 681 | 0.00% | 2q | +1235.3%+$11.1K |
| US BANCORP \DE\ | $7.3K | 403 | 0.00% | new | NEW |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $5.3K | 297 | 0.00% | new | NEW |
| Parallel Advisors, LLC | $4.8K | 264 | 0.00% | 2q | HELD |
| Allworth Financial LP | $2.9K | 161 | 0.00% | 2q | HELD |
| Sterling Capital Management LLC | $1.4K | 76 | 0.00% | new | NEW |
| SBI Securities Co., Ltd. | $1.2K | 68 | 0.00% | 5q | HELD |
| Fortitude Family Office, LLC | $720 | 40 | 0.00% | 2q | HELD |
| Quarry LP | $522 | 29 | 0.00% | new | NEW |
| OSAIC HOLDINGS, INC. | $468 | 26 | 0.00% | 4q | HELD |
| Caitong International Asset Management Co., Ltd | $378 | 21 | 0.00% | 2q | +425.0% |
| NATIONAL BANK OF CANADA /FI/ | $54 | 3 | 0.00% | new | NEW |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-10-27 | 13G | BlackRock, Inc. | 5.6% |
What the insiders did
Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.
Officers and directors
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-06-22 | Brumm Joshua T | Chief Executive Officer | Sold | 42,305 | $761.1K |
| 2026-06-22 | McNeill Jonathan | President and COO | Sold | 20,549 | $369.7K |
| 2026-09-18 | Brumm Joshua T | Chief Executive Officer | Sold | 7,837 | $131.0K |
Ten percent owners and entities
Usually an institution that crossed a reporting threshold, or a company taking a strategic stake, rather than an individual with a view.
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-07-16 | Fairmount Funds Management LLC | Director, 10% owner | Bought | 853,450 | $12.4M |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 11 | $23.9K | 1,639 | 7 | 3 | 0 | 0.0% |
| Q2 2026 | 82 | $532.6M | 29,586,731 | 32 | 17 | 15 | 0.0% |
| Q1 2026 | 63 | $476.6M | 25,949,547 | 16 | 17 | 8 | 0.0% |
| Q4 2025 | 56 | $285.9M | 24,116,294 | 20 | 16 | 8 | 0.0% |
| Q3 2025 | 40 | $134.6M | 11,318,882 | 15 | 6 | 8 | 0.0% |
| Q2 2025 | 29 | $173.5M | 10,751,740 | 29 | 0 | 0 | 0.0% |
| Q1 2025 | 2 | $55.2K | 22 | 2 | 0 | 0 | 99.7% |
| Q4 2024 | 3 | $13.7K | 15 | 2 | 0 | 0 | 98.7% |
| Q3 2024 | 1 | $355 | 0 | 1 | 0 | 0 | 100.0% |
| Q2 2024 | 2 | $129.9K | 0 | 0 | 0 | 0 | 100.0% |
| Q1 2024 | 2 | $527.3K | 0 | 0 | 0 | 0 | 100.0% |
| Q4 2023 | 3 | $216.7K | 66 | 3 | 0 | 0 | 99.2% |
| Q3 2023 | 31 | $1.1M | 2,152,048 | 5 | 5 | 8 | 7.6% |
| Q2 2023 | 29 | $887.0K | 2,270,207 | 6 | 3 | 8 | 10.2% |
| Q1 2023 | 35 | $898.9K | 3,371,739 | 8 | 9 | 6 | 21.3% |
| Q4 2022 | 35 | $3.4M | 4,993,985 | 10 | 5 | 9 | 21.6% |
| Q3 2022 | 34 | $5.3M | 7,948,888 | 4 | 8 | 9 | 24.6% |
| Q2 2022 | 39 | $21.3M | 8,248,981 | 7 | 3 | 14 | 31.5% |
| Q1 2022 | 44 | $6.7M | 9,896,653 | 2 | 6 | 19 | 2.6% |
| Q4 2021 | 50 | $14.8M | 15,333,130 | 11 | 12 | 12 | 5.3% |
| Q3 2021 | 67 | $82.3M | 18,599,092 | 13 | 6 | 30 | 7.0% |
| Q2 2021 | 70 | $89.8M | 20,238,367 | 11 | 17 | 29 | 2.4% |
| Q1 2021 | 89 | $116.5M | 22,392,749 | 21 | 37 | 18 | 3.1% |
| Q4 2020 | 80 | $93.1M | 14,375,282 | 15 | 29 | 16 | 2.6% |
| Q3 2020 | 78 | $61.0M | 14,090,125 | 10 | 32 | 20 | 0.7% |
| Q2 2020 | 78 | $84.2M | 14,017,625 | 38 | 20 | 16 | 2.3% |
| Q1 2020 | 44 | $48.0M | 10,757,471 | 13 | 16 | 11 | 2.0% |
| Q4 2019 | 44 | $52.5M | 7,659,537 | 11 | 12 | 15 | 0.6% |
| Q3 2019 | 39 | $36.7M | 7,442,390 | 10 | 11 | 15 | 0.3% |
| Q2 2019 | 48 | $57.0M | 7,670,021 | 11 | 19 | 15 | 0.7% |
| Q1 2019 | 61 | $68.7M | 8,228,140 | 11 | 21 | 24 | 2.9% |
| Q4 2018 | 64 | $60.8M | 7,583,790 | 3 | 0 | 2 | 1.6% |