DaveManuel.com · Institutional Ownership · Who Owns It
C4 THERAPEUTICS INC (CCCC)
Institutional ownership reported to the SEC as of Q2 2026, across 24 quarters.
149
Reporting holders
$552.9M
Reported value
95.6%
Of shares outstanding
0.8%
Calls
0.1%
Puts
+25
Holder change
Institutions report 117,654,816 shares against 123,025,136 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. A figure this high can overstate: where an adviser and a sub-adviser both report the same shares, both are counted.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| MORGAN STANLEY | $41.4M | 8,867,338 | 0.00% | 23q | -2.3%-$957.6K |
| RA CAPITAL MANAGEMENT, L.P. | $37.4M | 8,000,000 | 0.32% | 3q | HELD |
| BlackRock, Inc. | $36.9M | 7,896,718 | 0.00% | 8q | +285.5%+$27.3M |
| Squadron Capital Management LLC | $35.5M incl. $1.9M options CALL | 7,200,000 | 11.01% | 2q | +220.0%+$24.4M |
| Lynx1 Capital Management LP | $34.2M | 7,326,691 | 3.95% | 12q | +4.7%+$1.5M |
| Bain Capital Life Sciences Investors, LLC | $33.5M | 7,171,910 | 1.99% | 23q | HELD |
| JPMORGAN CHASE & CO | $20.7M | 4,747,424 | 0.00% | 23q | +47.3%+$6.6M |
| VANGUARD CAPITAL MANAGEMENT LLC | $20.6M | 4,417,731 | 0.00% | 2q | +14.4%+$2.6M |
| CITADEL ADVISORS LLC | $20.0M incl. $451.6K options CALL+PUT | 4,187,580 | 0.00% | 4q | +66.8%+$8.0M |
| GOLDMAN SACHS GROUP INC | $16.5M | 3,530,991 | 0.00% | 21q | +47.9%+$5.3M |
| WASATCH ADVISORS LP | $16.5M | 3,522,644 | 0.11% | 22q | +18.9%+$2.6M |
| TWO SIGMA INVESTMENTS, LP | $16.2M | 3,469,707 | 0.01% | 10q | +14.3%+$2.0M |
| Soleus Capital Management, L.P. | $15.8M | 3,377,981 | 0.54% | 23q | -11.2%-$2.0M |
| SILVERARC CAPITAL MANAGEMENT, LLC | $14.2M | 3,032,060 | 1.47% | 4q | +58.6%+$5.2M |
| BANK OF AMERICA CORP /DE/ | $12.4M | 2,656,359 | 0.00% | 23q | +12.6%+$1.4M |
| GEODE CAPITAL MANAGEMENT, LLC | $11.8M | 2,522,163 | 0.00% | 23q | +165.2%+$7.3M |
| Ikarian Capital, LLC | $11.4M | 2,433,000 | 1.22% | new | NEW |
| STATE STREET CORP | $9.9M | 2,115,621 | 0.00% | 23q | +452.4%+$8.1M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $9.5M incl. $1.4M options CALL+PUT | 1,732,210 | 0.00% | 22q | +34.6%+$2.4M |
| ACADIAN ASSET MANAGEMENT LLC | $8.4M | 1,806,199 | 0.01% | 6q | -4.5%-$395.3K |
| Candriam S.C.A. | $8.4M | 1,796,937 | 0.04% | new | NEW |
| D. E. Shaw & Co., Inc. | $8.1M | 1,740,989 | 0.00% | 17q | +64.2%+$3.2M |
| Patient Square Capital LP | $7.5M | 1,608,815 | 1.16% | new | NEW |
| HighVista Strategies LLC | $6.3M | 1,348,136 | 1.44% | new | NEW |
| RENAISSANCE TECHNOLOGIES LLC | $5.6M | 1,189,828 | 0.01% | 6q | -51.7%-$5.9M |
| DIMENSIONAL FUND ADVISORS LP | $5.5M | 1,188,507 | 0.00% | 16q | +168.6%+$3.5M |
| NORTHERN TRUST CORP | $5.4M | 1,160,547 | 0.00% | 23q | +512.5%+$4.5M |
| CONGRESS ASSET MANAGEMENT CO | $4.7M | 1,003,437 | 0.03% | 2q | +20.8%+$807.0K |
| FMR LLC | $4.2M | 894,054 | 0.00% | 23q | +228.3%+$2.9M |
| UBS Group AG | $3.9M | 828,970 | 0.00% | 23q | +284.0%+$2.9M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $3.6M | 781,060 | 0.00% | 23q | +72.7%+$1.5M |
| BOOTHBAY FUND MANAGEMENT, LLC | $3.4M | 736,331 | 0.05% | new | NEW |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $3.2M | 680,094 | 0.00% | new | NEW |
| VANGUARD FIDUCIARY TRUST CO | $2.8M | 609,146 | 0.00% | 2q | +25.8%+$583.8K |
| ExodusPoint Capital Management, LP | $2.7M | 580,195 | 0.02% | 3q | +1121.3%+$2.5M |
| Velan Capital Investment Management LP | $2.7M | 570,000 | 1.62% | new | NEW |
| STEMPOINT CAPITAL LP | $2.4M | 523,648 | 0.42% | 2q | -42.2%-$1.8M |
| Rockefeller Capital Management L.P. | $2.3M | 495,817 | 0.00% | new | NEW |
| Nuveen, LLC | $2.3M | 484,010 | 0.00% | new | NEW |
| WELLS FARGO & COMPANY/MN | $2.1M | 452,701 | 0.00% | 14q | -47.8%-$1.9M |
| Man Group plc | $1.9M | 408,648 | 0.00% | 6q | +59.3%+$710.7K |
| PLATINUM INVESTMENT MANAGEMENT LTD | $1.8M | 384,766 | 0.44% | 2q | HELD |
| Seven Fleet Capital Management LP | $1.8M | 381,169 | 0.29% | 2q | +567.8%+$1.5M |
| Qube Research & Technologies Ltd | $1.7M | 370,554 | 0.00% | 4q | -50.7%-$1.8M |
| Atom Investors LP | $1.7M | 364,351 | 0.15% | 3q | +167.8%+$1.1M |
| JANE STREET GROUP, LLC | $1.6M incl. $234.9K options CALL | 302,750 | 0.00% | 11q | -75.7%-$5.1M |
| Susquehanna Portfolio Strategies, LLC | $1.6M | 335,079 | 0.02% | 5q | +28.7%+$349.3K |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $1.5M | 325,000 | 0.00% | new | NEW |
| Connor, Clark & Lunn Investment Management Ltd. | $1.4M | 300,734 | 0.00% | 3q | +8.5%+$110.0K |
| ADAR1 Capital Management, LLC | $1.4M | 291,957 | 0.06% | 2q | +579.0%+$1.2M |
| Invesco Ltd. | $1.4M | 290,226 | 0.00% | 23q | +18.7%+$213.5K |
| PANAGORA ASSET MANAGEMENT INC | $1.2M | 264,947 | 0.00% | 2q | +205.4%+$832.1K |
| LPL Financial LLC | $1.2M | 253,165 | 0.00% | 9q | +2.6%+$29.7K |
| Bank of New York Mellon Corp | $1.2M | 249,517 | 0.00% | new | NEW |
| WELLINGTON MANAGEMENT GROUP LLP | $1.1M | 227,768 | 0.00% | new | NEW |
| MARSHALL WACE, LLP | $1.1M | 227,003 | 0.00% | 4q | +46.0%+$333.9K |
| MILLENNIUM MANAGEMENT LLC | $1.0M | 215,386 | 0.00% | 14q | -84.5%-$5.5M |
| Caption Management, LLC | $989.1K incl. $825.7K options CALL | 35,000 | 0.00% | new | NEW |
| Jump Financial, LLC | $853.2K | 182,700 | 0.01% | new | NEW |
| Point72 Asset Management, L.P. | $812.4K | 173,965 | 0.00% | 3q | +2.9%+$22.7K |
| Squarepoint Ops LLC | $797.8K | 170,834 | 0.00% | 5q | +320.1%+$607.9K |
| PRICE T ROWE ASSOCIATES INC /MD/ | $728.0K | 155,881 | 0.00% | 23q | +117.9%+$393.9K |
| Headlands Technologies LLC | $719.0K | 153,972 | 0.08% | new | NEW |
| AMERICAN CENTURY COMPANIES INC | $703.7K | 150,681 | 0.00% | 4q | +76.4%+$304.7K |
| XTX Topco Ltd | $632.5K | 135,438 | 0.01% | 6q | +187.2%+$412.3K |
| Palumbo Wealth Management LLC | $618.4K | 132,417 | 0.13% | new | NEW |
| RHUMBLINE ADVISERS | $615.9K | 131,877 | 0.00% | 23q | +4755.6%+$603.2K |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $612.2K | 131,100 | 0.01% | 6q | HELD |
| Walleye Capital LLC | $539.0K incl. $1.4K options CALL | 115,125 | 0.00% | 4q | -51.9%-$580.6K |
| ALPS ADVISORS INC | $524.0K | 112,214 | 0.00% | new | NEW |
| CANADA PENSION PLAN INVESTMENT BOARD | $474.0K | 101,500 | 0.00% | 3q | -25.1%-$159.2K |
| DEUTSCHE BANK AG\ | $461.7K | 98,873 | 0.00% | new | NEW |
| Virtu Financial LLC | $458.0K | 98,094 | 0.01% | new | NEW |
| Verition Fund Management LLC | $443.6K | 95,000 | 0.00% | new | NEW |
| Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group | $396.9K | 85,000 | 0.10% | 19q | HELD |
| BARCLAYS PLC | $348.0K | 74,516 | 0.00% | 18q | -76.6%-$1.1M |
| BNP PARIBAS FINANCIAL MARKETS | $347.3K | 74,373 | 0.00% | 7q | -60.9%-$541.6K |
| Crestwood Advisors Group, LLC | $310.7K | 66,536 | 0.00% | 5q | HELD |
| INTREPID FAMILY OFFICE LLC | $303.6K | 65,000 | 0.22% | 7q | +8.3%+$23.4K |
| CV Advisors LLC | $303.6K | 65,000 | 0.06% | new | NEW |
| MetLife Investment Management, LLC | $286.7K | 61,393 | 0.00% | new | NEW |
| Jain Global LLC | $268.8K | 57,562 | 0.00% | 3q | -7.7%-$22.5K |
| Thrivent Financial for Lutherans | $247.0K | 52,763 | 0.00% | new | NEW |
| CITIGROUP INC | $230.6K | 49,389 | 0.00% | 23q | +16.4%+$32.5K |
| GROUP ONE TRADING LLC | $224.0K incl. $122.4K options CALL+PUT | 21,773 | 0.00% | new | NEW |
| SIMPLEX TRADING, LLC | $221.4K CALL+PUT | options only | 0.00% | 19q | OPTIONS |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $217.0K | 46,474 | 0.00% | new | NEW |
| SEI INVESTMENTS CO | $197.9K | 42,376 | 0.00% | 2q | +68.6%+$80.5K |
| Quadrature Capital Ltd | $171.5K | 36,726 | 0.00% | 3q | -41.5%-$121.6K |
| ALLIANCEBERNSTEIN L.P. | $170.4K | 64,780 | 0.00% | new | NEW |
| Vanguard Global Advisers, LLC | $158.0K | 33,832 | 0.00% | 2q | HELD |
| Dynamic Technology Lab Private Ltd | $153.0K | 32,828 | 0.03% | new | NEW |
| PRUDENTIAL FINANCIAL INC | $145.9K | 31,235 | 0.00% | 4q | +95.8%+$71.4K |
| HRT FINANCIAL LP | $142.0K incl. $142.0K options OPT | 30,600 | 0.00% | 2q | -72.5%-$373.6K |
| Police & Firemen's Retirement System of New Jersey | $139.6K | 29,893 | 0.00% | new | NEW |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $128.5K | 27,513 | 0.00% | new | NEW |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $117.3K | 25,111 | 0.00% | 2q | -90.5%-$1.1M |
| Cresset Asset Management, LLC | $116.8K | 25,000 | 0.00% | 9q | HELD |
| NEW YORK STATE COMMON RETIREMENT FUND | $112.5K | 24,100 | 0.00% | new | NEW |
| StoneX Group Inc. | $102.3K | 22,420 | 0.00% | new | NEW |
Showing the largest 100 of 149 reported holders.
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 19 | $18.8M | 5,642,679 | 2 | 7 | 2 | 0.0% |
| Q2 2026 | 149 | $552.9M | 117,654,816 | 52 | 53 | 30 | 1.0% |
| Q1 2026 | 124 | $223.9M | 85,055,570 | 31 | 40 | 30 | 0.6% |
| Q4 2025 | 101 | $153.4M | 79,863,329 | 22 | 43 | 18 | 0.6% |
| Q3 2025 | 99 | $118.1M | 52,543,424 | 25 | 26 | 36 | 1.2% |
| Q2 2025 | 103 | $78.7M | 54,928,543 | 25 | 31 | 31 | 0.2% |
| Q1 2025 | 117 | $102.7M | 64,129,393 | 26 | 36 | 27 | 0.1% |
| Q4 2024 | 116 | $234.6M | 64,400,415 | 19 | 37 | 32 | 1.2% |
| Q3 2024 | 122 | $371.8M | 64,206,503 | 33 | 37 | 30 | 1.6% |
| Q2 2024 | 115 | $286.1M | 60,913,252 | 33 | 30 | 34 | 1.6% |
| Q1 2024 | 105 | $495.4M | 59,246,128 | 39 | 27 | 27 | 2.3% |
| Q4 2023 | 92 | $281.3M | 47,213,252 | 30 | 29 | 22 | 5.2% |
| Q3 2023 | 84 | $64.5M | 34,671,251 | 7 | 29 | 28 | 0.1% |
| Q2 2023 | 100 | $94.3M | 34,222,797 | 17 | 36 | 35 | 0.2% |
| Q1 2023 | 120 | $117.9M | 37,485,359 | 21 | 44 | 34 | 0.2% |
| Q4 2022 | 117 | $231.6M | 39,213,865 | 14 | 37 | 35 | 0.1% |
| Q3 2022 | 112 | $1.2B | 138,318,259 | 16 | 42 | 29 | 0.0% |
| Q2 2022 | 114 | $1.3B | 172,475,787 | 28 | 33 | 34 | 0.2% |
| Q1 2022 | 121 | $3.4B | 139,677,503 | 27 | 42 | 31 | 0.5% |
| Q4 2021 | 119 | $3.0B | 93,925,716 | 19 | 42 | 30 | 0.1% |
| Q3 2021 | 111 | $2.0B | 44,843,450 | 18 | 51 | 21 | 0.2% |
| Q2 2021 | 106 | $1.7B | 44,378,920 | 37 | 43 | 12 | 0.2% |
| Q1 2021 | 82 | $1.1B | 28,825,364 | 17 | 27 | 20 | 0.0% |
| Q4 2020 | 74 | $867.0M | 26,434,666 | 69 | 0 | 0 | 0.0% |