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DaveManuel.com · Institutional Ownership · Who Owns It

CRISPR THERAPEUTICS AG (CRSP)

Institutional ownership reported to the SEC as of Q2 2026, across 32 quarters.

529
Reporting holders
$4.3B
Reported value
78.9%
Of shares outstanding
2.1%
Calls
2.2%
Puts
+28
Holder change

Institutions report 76,290,826 shares against 96,692,653 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end.

Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.

Holders

Download these holders as CSV

FilerValueShares Their book Held Change
ARK Investment Management LLC$516.0M9,460,9393.35%31q-16.4%-$101.0M
BlackRock, Inc.$455.4M8,348,9770.01%8q+8.7%+$36.5M
Orbis Allan Gray Ltd$297.2M5,449,1611.02%7q-10.8%-$35.8M
Capital World Investors$259.0M4,749,5250.03%2q+0.5%+$1.3M
STATE STREET CORP$235.7M4,321,6660.01%31q+8.5%+$18.5M
GSK plc$175.7M3,220,62729.17%3qHELD
GEODE CAPITAL MANAGEMENT, LLC$136.9M2,509,9150.01%31q+5.6%+$7.2M
T. Rowe Price Investment Management, Inc.$112.0M2,053,0170.07%16q-30.5%-$49.1M
SR One Capital Management, LP$111.2M2,038,76310.70%10qHELD
TWO SIGMA INVESTMENTS, LP$108.5M1,988,6210.08%31q+34.1%+$27.6M
FMR LLC$104.1M1,908,5030.00%31q-2.4%-$2.5M
Sumitomo Mitsui Trust Group, Inc.$93.8M1,720,7340.05%18q-7.2%-$7.3M
Amova Asset Management Americas, Inc.$93.8M1,720,0971.21%31q-7.2%-$7.3M
EcoR1 Capital, LLC$75.8M1,389,2763.68%10qHELD
UBS Group AG$72.0M
incl. $136.3K options CALL
1,317,4990.01%31q-25.2%-$24.3M
Capital International Investors$69.2M1,268,4070.01%31q+6.9%+$4.5M
VANGUARD CAPITAL MANAGEMENT LLC$64.5M1,181,8470.00%2q+3.4%+$2.1M
BANK OF AMERICA CORP /DE/$63.0M1,155,1050.00%31q+17.5%+$9.4M
SUSQUEHANNA INTERNATIONAL GROUP, LLP$59.5M
incl. $36.2M options CALL+PUT
427,1780.00%31q-28.0%-$23.2M
NEA Management Company, LLC$57.7M1,058,5703.64%31qHELD
CHARLES SCHWAB INVESTMENT MANAGEMENT INC$57.7M1,057,8370.01%18q+1.8%+$1.0M
CITADEL ADVISORS LLC$55.2M
incl. $29.8M options CALL+PUT
465,7960.01%31q-9.8%-$6.0M
D. E. Shaw & Co., Inc.$55.0M
incl. $6.2M options CALL+PUT
893,8120.03%31qHELD
MORGAN STANLEY$48.0M879,9490.00%35q+31.7%+$11.6M
NORTHERN TRUST CORP$47.1M863,0910.01%31q+7.6%+$3.3M
VANGUARD PORTFOLIO MANAGEMENT LLC$35.4M648,7130.00%2q+18.6%+$5.6M
IMC-Chicago, LLC$31.1M
incl. $30.5M options CALL+PUT
10,7090.01%19qHELD
VANGUARD FIDUCIARY TRUST CO$31.1M570,0400.01%2q+5.0%+$1.5M
JPMORGAN CHASE & CO$24.6M431,6690.00%31q-5.7%-$1.5M
MILLENNIUM MANAGEMENT LLC$24.0M
incl. $3.1M options CALL
382,0320.01%23q+1.3%+$304.7K
IQ EQ FUND MANAGEMENT (IRELAND) Ltd$20.8M381,9911.33%9q-4.7%-$1.0M
JANE STREET GROUP, LLC$18.6M
incl. $18.4M options CALL+PUT
3,7800.00%27qHELD
Bank of New York Mellon Corp$17.8M326,7610.00%31q+4.9%+$838.7K
PEAK6 LLC$16.7M
incl. $15.5M options CALL+PUT
22,3160.03%7q-79.5%-$64.5M
Logos Global Management LP$16.4M300,0000.70%newNEW
Squarepoint Ops LLC$15.9M
incl. $229.1K options CALL
286,7890.02%16q+86.7%+$7.4M
Jump Financial, LLC$15.2M277,9520.12%3q+158.7%+$9.3M
DIMENSIONAL FUND ADVISORS LP$15.0M275,3750.00%27q-44.3%-$11.9M
GOLDMAN SACHS GROUP INC$14.9M272,3720.00%31q-34.2%-$7.7M
NORGES BANK$14.8M270,7560.00%26q-44.8%-$12.0M
WELLS FARGO & COMPANY/MN$14.4M263,1690.00%31q-6.2%-$956.6K
GROUP ONE TRADING LLC$13.7M
incl. $9.0M options CALL+PUT
85,0400.02%31q-11.4%-$1.8M
AMERIPRISE FINANCIAL INC$13.7M250,6140.00%31q-12.6%-$2.0M
Vestmark Advisory Solutions, Inc.$13.2M242,2660.12%11q-5.7%-$791.5K
RAYMOND JAMES FINANCIAL INC$12.7M231,9880.00%7q+5.3%+$638.9K
CITIGROUP INC$11.8M
incl. $5.6M options CALL+PUT
114,3160.00%31q+420.3%+$9.5M
Nuveen, LLC$11.1M203,0890.00%5q+6.5%+$672.1K
ROYAL BANK OF CANADA$9.4M173,0450.00%31q+5.7%+$508.6K
Marex Group Ltd$9.3M170,5840.04%15q+27.2%+$2.0M
Swiss National Bank$9.2M169,2000.00%31qHELD
Susquehanna Portfolio Strategies, LLC$8.9M164,0260.14%6q+55.7%+$3.2M
Legal & General Group Plc$8.9M163,8100.00%31q+116.6%+$4.8M
LPL Financial LLC$8.4M153,5810.00%31q+1.0%+$83.9K
Versant Venture Management, LLC$8.1M148,8314.99%31qHELD
Pictet Asset Management Holding SA$8.0M142,2130.01%12q-7.7%-$662.6K
Life Cycle Investment Partners Ltd$7.8M143,6920.04%newNEW
TD Asset Management Inc$7.8M142,6020.01%23q-10.0%-$862.5K
HRT FINANCIAL LP$7.8M
incl. $430.0K options OPT
142,5640.01%3q+102.1%+$3.9M
AMERICAN CENTURY COMPANIES INC$7.6M139,4620.00%17q+15.7%+$1.0M
Walleye Trading LLC$7.5M
incl. $6.5M options CALL+PUT
18,5950.01%31q+23.3%+$1.4M
SFE Investment Counsel$7.1M
incl. $6.2M options PUT
16,3650.96%11q+15.9%+$977.0K
PRICE T ROWE ASSOCIATES INC /MD/$7.0M128,5830.00%31q+22.5%+$1.3M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.$6.7M122,6580.01%9q+29.5%+$1.5M
RHUMBLINE ADVISERS$6.6M121,5110.00%5q+5.8%+$364.8K
KBC Group NV$6.4M116,8470.01%12qHELD
Private Advisor Group, LLC$6.1M111,1290.03%14q+4.2%+$243.6K
EverSource Wealth Advisors, LLC$6.0M110,6890.20%17q+23.4%+$1.1M
CONGRESS ASSET MANAGEMENT CO$6.0M109,4530.04%12q+1.0%+$59.0K
Campbell & CO Investment Adviser LLC$5.9M107,5290.31%newNEW
California Public Employees Retirement System$5.6M102,6690.00%31q-11.6%-$732.9K
DEUTSCHE BANK AG\$5.6M101,8540.00%34q+22.2%+$1.0M
Rockefeller Capital Management L.P.$5.5M101,6490.01%31q+38.6%+$1.5M
CAPITAL INTERNATIONAL SARL$5.5M101,2380.08%24q-1.0%-$56.7K
Affinity Asset Advisors, LLC$5.5M100,0000.25%2q-33.3%-$2.7M
ALLIANCEBERNSTEIN L.P.$5.4M114,3370.00%5q+18.7%+$855.3K
CLOUGH CAPITAL PARTNERS L P$5.4M98,3370.44%4q+298.4%+$4.0M
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM$5.4M98,1680.00%20q-3.0%-$167.1K
Zurcher Kantonalbank (Zurich Cantonalbank)$5.2M94,8380.01%31q+10.2%+$480.4K
Slow Capital, Inc.$5.1M92,8940.59%30q+1.8%+$91.1K
Concurrent Investment Advisors, LLC$5.0M
incl. $109.1K options CALL
90,5370.04%5q+45.0%+$1.6M
Cambridge Investment Research Advisors, Inc.$5.0M92,4200.01%29q+143.3%+$3.0M
NOMURA HOLDINGS INC$5.0M
incl. $2.0M options CALL+PUT
56,0270.01%2q+962.5%+$4.5M
CAPITAL FUND MANAGEMENT S.A.$4.9M89,2420.02%22q-6.8%-$356.0K
VANGUARD ASSET MANAGEMENT, Ltd$4.7M86,5500.00%2q+12.6%+$528.4K
CREDIT AGRICOLE S A$4.7M85,9300.01%newNEW
HIMENSION CAPITAL (SINGAPORE) PTE. LTD.$4.6M83,8970.28%11q-9.3%-$468.2K
STATE OF MICHIGAN RETIREMENT SYSTEM$4.5M82,5470.02%newNEW
TUDOR INVESTMENT CORP ET AL$4.4M
incl. $2.1M options CALL+PUT
42,5120.01%8q-2.1%-$93.7K
OSAIC HOLDINGS, INC.$4.3M79,5010.01%26q+32.4%+$1.1M
Fisher Asset Management, LLC$4.3M77,9600.00%newNEW
Trexquant Investment LP$4.2M77,4710.02%2q-39.1%-$2.7M
COMMONWEALTH EQUITY SERVICES, LLC$4.2M76,9000.01%31q-2.0%-$86.6K
Russell Investments Group, Ltd.$4.2M76,2660.00%4q+60.7%+$1.6M
SIMPLEX TRADING, LLC$4.1M CALL+PUToptions only0.00%31qOPTIONS
JONES FINANCIAL COMPANIES LLLP$4.1M73,8470.00%10q+16.0%+$559.1K
Man Group plc$4.0M73,1940.01%3q-18.7%-$919.9K
ENVESTNET ASSET MANAGEMENT INC$3.8M70,0810.00%24q-14.7%-$661.3K
Caption Management, LLC$3.8M CALL+PUToptions only0.02%13qOPTIONS
Shah Wealth Advisors, LLC$3.8M69,0600.87%newFIRST
ALGERT GLOBAL LLC$3.6M65,8800.04%3q-32.0%-$1.7M

Showing the largest 100 of 531 reported holders. The count of 529 above leaves out 2 positions whose reported value failed our price check; they are listed here as filed.

What the company announced

Form 8-K filings from the last 120 days, showing only the items worth a reader's attention. Earnings releases, exhibit attachments and general disclosures are filed constantly and are left out. Filed is when the SEC received it; event is the date the company says the thing happened.

FiledEvent dateWhatSource
2026-10-192026-10-19Directors or officers departed or appointedfiling

What the insiders did

Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.

Officers and directors

DateInsiderRoleSideSharesValue
2026-10-19Kulkarni SamarthChief Executive OfficerSold47,837$2.4M
2026-09-17Behbahani AliDirectorSold13,679$780.9K
2026-10-14George SimeonDirectorSold14,514$720.4K
2026-09-22KASINGER JAMES R.General Counsel and SecretarySold10,400$626.5K
2026-05-29Patel NaimishChief Medical OfficerSold3,786$210.6K
2026-10-14Kulkarni SamarthChief Executive OfficerSold4,098$201.9K
2026-10-06KASINGER JAMES R.General Counsel and SecretarySold1,990$119.5K

Quarter by quarter

Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.

QuarterHoldersValue SharesNewAdded TrimmedOptions
Q3 2026142$157.6M2,850,7861841250.0%
Q2 2026529$4.3B76,290,826731531384.3%
Q1 2026501$3.9B77,169,712681661176.0%
Q4 2025495$4.5B78,383,035691451229.3%
Q3 2025461$5.3B72,848,8817813911511.5%
Q2 2025450$4.0B72,783,17510412510411.7%
Q1 2025403$2.4B64,679,24752122977.2%
Q4 2024412$2.7B64,564,732441141206.4%
Q3 2024422$3.0B60,266,751401251275.7%
Q2 2024459$3.5B59,907,952461521217.1%
Q1 2024492$4.8B61,810,397711501369.9%
Q4 2023484$4.2B56,437,7959912912014.9%
Q3 2023417$2.7B55,223,98835150906.4%
Q2 2023427$3.3B54,776,20767921347.6%
Q1 2023382$2.8B58,416,401451031145.4%
Q4 2022401$2.7B61,172,500421121227.3%
Q3 2022430$8.1B116,794,655491191165.4%
Q2 2022429$6.5B101,629,881531251135.7%
Q1 2022436$7.4B108,212,64365164914.1%
Q4 2021440$6.8B82,525,021431581277.4%
Q3 2021468$10.6B87,931,596531851116.7%
Q2 2021499$16.7B95,653,7991091651216.7%
Q1 2021435$11.9B91,398,208100168936.4%
Q4 2020413$15.6B97,303,962123129854.5%
Q3 2020309$5.2B60,417,8746292802.5%
Q2 2020278$311.8B4,240,053,8906389610.1%
Q1 2020258$180.7B4,285,911,5604691570.0%
Q4 2019257$258.6B4,244,790,2247467490.0%
Q3 2019187$174.8B4,262,070,5662751480.0%
Q2 2019188$201.6B4,277,243,2384244360.0%
Q1 2019176$154.2B4,317,231,3603540400.0%
Q4 2018158$104.5B3,655,007,0292430.0%