DaveManuel.com · Institutional Ownership · Who Owns It
CYTOKINETICS INC (CYTK)
Institutional ownership reported to the SEC as of Q2 2026, across 32 quarters.
494
Reporting holders
$14.4B
Reported value
115.4%
Of shares outstanding
4.4%
Calls
0.7%
Puts
+38
Holder change
Institutions report 160,448,447 shares against 139,023,418 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| BlackRock, Inc. | $1.7B | 20,094,362 | 0.03% | 8q | +21.4%+$302.1M |
| T. Rowe Price Investment Management, Inc. | $1.6B | 18,718,498 | 1.05% | 15q | +6.8%+$101.8M |
| WELLINGTON MANAGEMENT GROUP LLP | $590.5M | 6,931,770 | 0.10% | 25q | -13.5%-$91.8M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $571.8M | 6,711,799 | 0.03% | 2q | +14.9%+$73.9M |
| STATE STREET CORP | $553.2M | 6,494,233 | 0.02% | 31q | +13.0%+$63.8M |
| VANGUARD CAPITAL MANAGEMENT LLC | $521.2M | 6,117,515 | 0.01% | 2q | +11.5%+$53.6M |
| FMR LLC | $428.7M | 5,031,782 | 0.02% | 31q | -53.1%-$484.8M |
| Avoro Capital Advisors LLC | $425.9M | 4,999,999 | 3.82% | 2q | +50.0%+$142.0M |
| BANK OF AMERICA CORP /DE/ | $394.9M | 4,635,709 | 0.03% | 31q | +48.3%+$128.7M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $317.7M incl. $185.7M options CALL+PUT | 1,549,458 | 0.02% | 31q | +72.4%+$133.4M |
| GEODE CAPITAL MANAGEMENT, LLC | $316.3M | 3,712,501 | 0.02% | 31q | +15.5%+$42.4M |
| RTW INVESTMENTS, LP | $243.8M | 2,862,003 | 2.08% | 24q | +5.2%+$12.0M |
| ARMISTICE CAPITAL, LLC | $232.7M incl. $130.3M options CALL | 1,201,342 | 2.85% | 10q | +57.1%+$84.6M |
| Polar Capital Holdings Plc | $192.0M | 2,253,649 | 0.45% | 23q | +35.7%+$50.5M |
| CITADEL ADVISORS LLC | $167.5M incl. $112.9M options CALL+PUT | 640,945 | 0.02% | 31q | -41.7%-$120.0M |
| PRICE T ROWE ASSOCIATES INC /MD/ | $166.9M | 1,958,946 | 0.02% | 24q | +23.6%+$31.9M |
| GOLDMAN SACHS GROUP INC | $152.9M incl. $2.8M options CALL | 1,761,588 | 0.01% | 31q | -20.1%-$38.5M |
| Capital Research Global Investors | $143.7M | 1,686,625 | 0.02% | 2q | +118.8%+$78.0M |
| JPMORGAN CHASE & CO | $142.2M incl. $3.1M options CALL | 1,588,895 | 0.01% | 31q | +75.8%+$61.3M |
| NORTHERN TRUST CORP | $140.3M | 1,647,345 | 0.02% | 31q | +14.3%+$17.5M |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | $136.6M | 1,603,442 | 0.41% | 2q | +47.4%+$43.9M |
| Integral Health Asset Management, LLC | $136.3M | 1,600,000 | 5.38% | 26q | HELD |
| Point72 Asset Management, L.P. | $135.3M incl. $51.1K options PUT | 1,587,712 | 0.15% | 13q | +153.6%+$82.0M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $133.4M | 1,565,781 | 0.02% | 31q | +12.1%+$14.4M |
| MORGAN STANLEY | $128.7M | 1,510,318 | 0.01% | 35q | HELD |
| PRINCIPAL FINANCIAL GROUP INC | $111.7M | 1,311,664 | 0.05% | 31q | +20.0%+$18.6M |
| Capital International Investors | $111.2M | 1,305,848 | 0.02% | 7q | -2.5%-$2.8M |
| Invesco Ltd. | $105.2M | 1,235,323 | 0.01% | 31q | +154.7%+$63.9M |
| UBS Group AG | $99.8M | 1,171,287 | 0.01% | 31q | -43.6%-$77.2M |
| Pictet Asset Management Holding SA | $99.0M | 1,160,463 | 0.09% | 12q | +54.5%+$34.9M |
| Frazier Life Sciences Management, L.P. | $98.8M | 1,159,879 | 2.15% | 5q | HELD |
| Bank of New York Mellon Corp | $98.0M | 1,150,697 | 0.02% | 31q | +14.4%+$12.3M |
| Holocene Advisors, LP | $97.5M | 1,144,579 | 0.22% | new | NEW |
| Woodline Partners LP | $93.8M | 1,100,708 | 0.29% | 9q | +10.0%+$8.5M |
| D. E. Shaw & Co., Inc. | $89.3M | 1,048,103 | 0.04% | 10q | +48.3%+$29.1M |
| NORGES BANK | $86.5M | 1,015,522 | 0.01% | 16q | +25.8%+$17.8M |
| Royalty Pharma Sub-Manager, LLC | $83.5M | 980,392 | 34.52% | 3q | HELD |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $81.9M | 961,815 | 0.12% | 3q | +1883.8%+$77.8M |
| GW&K Investment Management, LLC | $78.0M | 916,107 | 0.61% | 4q | +85.2%+$35.9M |
| VANGUARD FIDUCIARY TRUST CO | $77.2M | 906,423 | 0.02% | 2q | +13.4%+$9.1M |
| FRANKLIN RESOURCES INC | $75.9M | 891,087 | 0.02% | 20q | +117.5%+$41.0M |
| JANE STREET GROUP, LLC | $72.9M incl. $72.4M options CALL+PUT | 6,084 | 0.01% | 27q | HELD |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $70.5M | 827,810 | 0.07% | 23q | +15.9%+$9.7M |
| GROUP ONE TRADING LLC | $67.3M CALL+PUT | options only | 0.09% | 31q | OPTIONS |
| Melqart Asset Management (UK) Ltd | $65.4M | 767,525 | 6.22% | 10q | -9.1%-$6.5M |
| Siren, L.L.C. | $64.7M | 758,952 | 1.31% | 2q | +23.6%+$12.4M |
| Fisher Asset Management, LLC | $63.4M | 743,697 | 0.02% | 11q | -3.2%-$2.1M |
| Balyasny Asset Management L.P. | $62.3M incl. $1.7M options CALL | 711,676 | 0.08% | 4q | -28.3%-$24.6M |
| Foresite Capital Management IV, LLC | $60.9M | 714,695 | 20.98% | 4q | +42.0%+$18.0M |
| Deep Track Capital, LP | $59.6M | 700,000 | 0.87% | 9q | -49.1%-$57.4M |
| BNP PARIBAS FINANCIAL MARKETS | $58.7M | 689,077 | 0.02% | 31q | -19.3%-$14.1M |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | $56.3M | 660,310 | 3.08% | 7q | HELD |
| Qube Research & Technologies Ltd | $48.8M | 572,535 | 0.05% | 7q | -26.5%-$17.6M |
| BROWN ADVISORY INC | $48.6M | 570,664 | 0.08% | 10q | -7.2%-$3.7M |
| EVENTIDE ASSET MANAGEMENT, LLC | $48.1M | 564,398 | 0.64% | 15q | +17.8%+$7.3M |
| Affinity Asset Advisors, LLC | $46.9M | 550,000 | 2.12% | 4q | -21.5%-$12.8M |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $46.8M | 549,348 | 0.01% | 9q | +76.3%+$20.2M |
| FEDERATED HERMES, INC. | $45.8M | 538,022 | 0.07% | 10q | -23.1%-$13.8M |
| First Turn Management, LLC | $44.9M | 527,412 | 4.81% | 4q | +85.9%+$20.8M |
| AMERICAN CENTURY COMPANIES INC | $44.2M | 518,398 | 0.02% | 20q | +16.8%+$6.3M |
| Caption Management, LLC | $43.7M CALL | options only | 0.20% | 12q | OPTIONS |
| Checkpoint Capital L.P. | $40.5M | 475,000 | 10.38% | 4q | +163.9%+$25.1M |
| Hood River Capital Management LLC | $40.0M | 469,273 | 0.29% | new | NEW |
| EMERALD ADVISERS, LLC | $39.0M | 457,956 | 0.92% | 2q | +130.3%+$22.1M |
| ADAR1 Capital Management, LLC | $39.0M | 457,907 | 1.79% | 11q | -27.6%-$14.9M |
| AMERIPRISE FINANCIAL INC | $38.7M | 454,851 | 0.01% | 31q | +50.2%+$13.0M |
| MARSHALL WACE, LLP | $38.5M | 451,467 | 0.03% | 19q | -31.2%-$17.5M |
| Nuveen, LLC | $38.1M | 447,185 | 0.01% | 6q | +27.1%+$8.1M |
| Candriam S.C.A. | $37.7M | 443,066 | 0.17% | 3q | +32.2%+$9.2M |
| RHUMBLINE ADVISERS | $35.9M | 421,799 | 0.03% | 31q | +14.1%+$4.4M |
| ALLIANCEBERNSTEIN L.P. | $35.3M | 535,993 | 0.01% | 31q | +16.8%+$5.1M |
| Handelsbanken Fonder AB | $34.5M | 405,000 | 0.10% | 23q | +63.8%+$13.4M |
| GILDER GAGNON HOWE & CO LLC | $34.1M | 400,245 | 0.35% | 16q | +20.9%+$5.9M |
| TD Asset Management Inc | $32.8M | 385,130 | 0.03% | 19q | -8.5%-$3.0M |
| CITIGROUP INC | $32.3M incl. $4.8M options CALL | 322,932 | 0.01% | 31q | +29.6%+$7.4M |
| VOYA INVESTMENT MANAGEMENT LLC | $31.4M | 368,698 | 0.03% | 31q | +42.1%+$9.3M |
| GSK plc | $29.0M | 340,434 | 4.82% | 3q | HELD |
| SPHERA FUNDS MANAGEMENT LTD. | $27.3M incl. $8.5M options CALL | 219,987 | 3.56% | 12q | +452.5%+$22.3M |
| TWO SIGMA INVESTMENTS, LP | $27.0M | 317,411 | 0.02% | 3q | +11.4%+$2.8M |
| BANK OF MONTREAL /CAN/ | $26.0M incl. $1.7M options PUT | 285,688 | 0.01% | 31q | +1855.2%+$24.7M |
| E. Ohman J:or Asset Management AB | $25.9M | 304,611 | 0.60% | 6q | +1.3%+$327.9K |
| Russell Investments Group, Ltd. | $25.7M | 301,566 | 0.02% | 27q | +73.3%+$10.9M |
| Trails Edge Capital Partners, LP | $24.5M | 288,089 | 3.90% | 2q | -4.0%-$1.0M |
| EMERALD MUTUAL FUND ADVISERS TRUST | $23.8M | 279,769 | 0.84% | 2q | +106.5%+$12.3M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $23.3M | 273,031 | 0.00% | 31q | +13.5%+$2.8M |
| Walleye Capital LLC | $23.1M incl. $2.7M options CALL+PUT | 239,728 | 0.08% | 6q | HELD |
| Polaris Capital Management, LLC | $22.7M | 266,900 | 2.14% | new | NEW |
| SEGALL BRYANT & HAMILL, LLC | $21.9M | 257,063 | 0.26% | 9q | +42.7%+$6.5M |
| Alyeska Investment Group, L.P. | $21.3M | 250,000 | 0.05% | 2q | +66.7%+$8.5M |
| ExodusPoint Capital Management, LP | $21.2M | 249,259 | 0.14% | 3q | +377.3%+$16.8M |
| Capital World Investors | $21.2M | 248,815 | 0.00% | 2q | +2.8%+$577.1K |
| TUDOR INVESTMENT CORP ET AL | $21.1M incl. $13.2M options CALL+PUT | 92,680 | 0.03% | 4q | HELD |
| Jupiter Topco LLC | $20.8M | 244,417 | 0.01% | new | FIRST |
| Sarissa Capital Management LP | $19.5M | 228,623 | 10.95% | 10q | HELD |
| Swiss National Bank | $18.9M | 222,400 | 0.01% | 31q | -3.2%-$630.4K |
| DEUTSCHE BANK AG\ | $18.4M | 216,540 | 0.01% | 34q | +15.7%+$2.5M |
| PRUDENTIAL FINANCIAL INC | $18.3M | 214,535 | 0.02% | 31q | +261.0%+$13.2M |
| BAKER BROS. ADVISORS LP | $18.0M | 211,267 | 0.09% | new | NEW |
| California Public Employees Retirement System | $18.0M | 211,052 | 0.01% | 16q | +6.3%+$1.1M |
| MILLENNIUM MANAGEMENT LLC | $17.9M incl. $8.5M options CALL | 109,717 | 0.01% | 31q | +12.0%+$1.9M |
Showing the largest 100 of 495 reported holders. The count of 494 above leaves out 1 position whose reported value failed our price check; it is listed here as filed.
What the insiders did
Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.
Officers and directors
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-09-15 | Blum Robert I | President & CEO | Sold | 97,926 | $6.8M |
| 2026-06-24 | Lee Sung | EVP, Chief Financial Officer | Sold | 38,730 | $3.2M |
| 2026-07-01 | Callos Andrew | EVP, Chief Commercial Officer | Sold | 15,000 | $1.3M |
| 2026-07-30 | Callos Andrew | EVP, Chief Commercial Officer | Sold | 14,000 | $1.1M |
| 2026-06-01 | Callos Andrew | EVP, Chief Commercial Officer | Sold | 15,000 | $1.1M |
| 2026-08-31 | Callos Andrew | EVP, Chief Commercial Officer | Sold | 10,000 | $702.4K |
| 2026-07-01 | Blum Robert I | President & CEO | Sold | 7,500 | $636.9K |
| 2026-07-13 | Blum Robert I | President & CEO | Sold | 7,500 | $615.1K ×2 |
| 2026-07-27 | Blum Robert I | President & CEO | Sold | 7,500 | $606.5K |
| 2026-05-14 | Blum Robert I | President & CEO | Sold | 7,500 | $584.4K |
| 2026-05-27 | Blum Robert I | President & CEO | Sold | 7,500 | $579.1K |
| 2026-08-10 | Blum Robert I | President & CEO | Sold | 7,500 | $575.7K |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 101 | $128.3M | 1,948,977 | 19 | 41 | 13 | 0.0% |
| Q2 2026 | 494 | $14.4B | 160,448,447 | 88 | 236 | 99 | 5.1% |
| Q1 2026 | 456 | $10.4B | 146,363,592 | 75 | 167 | 135 | 7.3% |
| Q4 2025 | 440 | $10.1B | 148,968,121 | 85 | 140 | 131 | 5.9% |
| Q3 2025 | 390 | $8.3B | 142,479,323 | 104 | 121 | 102 | 5.4% |
| Q2 2025 | 319 | $4.8B | 137,719,203 | 28 | 140 | 104 | 5.5% |
| Q1 2025 | 358 | $5.7B | 136,074,473 | 55 | 136 | 104 | 4.0% |
| Q4 2024 | 354 | $6.5B | 131,352,321 | 30 | 110 | 129 | 4.4% |
| Q3 2024 | 357 | $7.7B | 137,579,421 | 43 | 139 | 93 | 5.7% |
| Q2 2024 | 358 | $7.7B | 136,711,516 | 39 | 151 | 99 | 4.3% |
| Q1 2024 | 401 | $9.5B | 120,598,261 | 97 | 124 | 121 | 10.6% |
| Q4 2023 | 368 | $12.2B | 118,843,783 | 116 | 74 | 108 | 18.3% |
| Q3 2023 | 258 | $3.3B | 109,996,751 | 24 | 92 | 78 | 2.6% |
| Q2 2023 | 256 | $3.6B | 110,415,999 | 27 | 94 | 76 | 0.6% |
| Q1 2023 | 267 | $4.4B | 124,086,565 | 37 | 76 | 91 | 0.5% |
| Q4 2022 | 279 | $5.1B | 109,264,127 | 32 | 100 | 88 | 1.2% |
| Q3 2022 | 276 | $6.7B | 136,296,102 | 39 | 104 | 81 | 0.9% |
| Q2 2022 | 260 | $5.6B | 138,227,687 | 48 | 96 | 68 | 0.7% |
| Q1 2022 | 234 | $4.5B | 121,313,801 | 19 | 91 | 80 | 0.4% |
| Q4 2021 | 247 | $6.3B | 138,202,577 | 48 | 75 | 74 | 0.3% |
| Q3 2021 | 210 | $4.1B | 113,216,771 | 51 | 91 | 40 | 0.6% |
| Q2 2021 | 185 | $1.9B | 97,588,966 | 22 | 58 | 60 | 0.8% |
| Q1 2021 | 187 | $2.3B | 97,227,461 | 30 | 56 | 60 | 0.4% |
| Q4 2020 | 178 | $2.0B | 96,070,283 | 31 | 54 | 56 | 1.2% |
| Q3 2020 | 181 | $2.1B | 92,167,436 | 44 | 82 | 36 | 5.4% |
| Q2 2020 | 159 | $5.2B | 218,626,913 | 30 | 60 | 46 | 0.3% |
| Q1 2020 | 148 | $3.4B | 284,009,266 | 26 | 54 | 40 | 0.7% |
| Q4 2019 | 138 | $2.7B | 257,521,187 | 23 | 49 | 39 | 0.2% |
| Q3 2019 | 145 | $2.8B | 248,378,386 | 20 | 51 | 36 | 0.4% |
| Q2 2019 | 132 | $713.9M | 62,549,837 | 17 | 66 | 23 | 2.9% |
| Q1 2019 | 132 | $458.9M | 56,589,496 | 15 | 58 | 26 | 1.7% |
| Q4 2018 | 130 | $359.5M | 56,748,311 | 4 | 3 | 1 | 0.2% |