INSMED INC (INSM)
Institutional ownership reported to the SEC as of Q2 2026, across 32 quarters.
Institutions report 223,999,265 shares against 218,381,503 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| FMR LLC | $1.7B | 16,143,583 | 0.07% | 31q | +22.7%+$318.1M |
| BlackRock, Inc. | $1.7B | 15,807,984 | 0.03% | 8q | -5.2%-$92.8M |
| JPMORGAN CHASE & CO | $1.2B incl. $92.7M options CALL+PUT | 10,428,170 | 0.07% | 31q | -56.8%-$1.6B |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $1.1B | 10,407,962 | 0.05% | 2q | HELD |
| VANGUARD CAPITAL MANAGEMENT LLC | $1.0B | 9,790,865 | 0.02% | 2q | +1.5%+$15.9M |
| BAKER BROS. ADVISORS LP | $937.8M | 8,796,111 | 4.70% | 31q | +18.5%+$146.6M |
| Capital International Investors | $878.3M | 8,238,124 | 0.18% | 10q | +47.2%+$281.8M |
| Darwin Global Management, Ltd. | $673.6M | 6,431,163 | 17.91% | 9q | -61.7%-$1.1B |
| AMERIPRISE FINANCIAL INC | $658.9M | 6,179,571 | 0.13% | 31q | +102.1%+$332.9M |
| Orbis Allan Gray Ltd | $647.9M | 6,076,487 | 2.23% | 5q | +224.5%+$448.2M |
| STATE STREET CORP | $645.3M | 6,052,174 | 0.02% | 31q | +9.0%+$53.4M |
| D. E. Shaw & Co., Inc. | $633.1M incl. $6.4M options CALL+PUT | 5,877,959 | 0.30% | 31q | +4.5%+$27.2M |
| Artisan Partners Limited Partnership | $580.2M | 5,441,718 | 0.92% | 9q | -16.6%-$115.7M |
| RTW INVESTMENTS, LP | $516.3M | 4,842,880 | 4.41% | 13q | HELD |
| GEODE CAPITAL MANAGEMENT, LLC | $448.8M | 4,220,155 | 0.02% | 31q | -5.2%-$24.5M |
| PRICE T ROWE ASSOCIATES INC /MD/ | $363.1M | 3,405,290 | 0.04% | 31q | +10.1%+$33.3M |
| NORGES BANK | $360.1M | 3,377,641 | 0.04% | 32q | +16.0%+$49.8M |
| CITADEL ADVISORS LLC | $339.9M incl. $67.3M options CALL+PUT | 2,556,973 | 0.04% | 31q | +17.2%+$49.8M |
| MILLENNIUM MANAGEMENT LLC | $312.2M incl. $93.8M options CALL+PUT | 2,048,005 | 0.11% | 14q | +76.9%+$135.7M |
| Duquesne Family Office LLC | $295.8M incl. $143.9M options CALL | 1,424,690 | 5.68% | 9q | +23.4%+$56.2M |
| Jupiter Topco LLC | $277.8M | 2,605,181 | 0.11% | new | FIRST |
| UBS Group AG | $275.8M incl. $214.9K options CALL | 2,584,446 | 0.04% | 31q | +48.7%+$90.4M |
| FRANKLIN RESOURCES INC | $242.4M | 2,273,222 | 0.05% | 29q | -13.1%-$36.7M |
| GOLDMAN SACHS GROUP INC | $241.1M incl. $90.8M options CALL+PUT | 1,409,885 | 0.02% | 31q | +49.6%+$79.9M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $230.7M incl. $153.0M options CALL+PUT | 729,354 | 0.02% | 31q | +320.1%+$175.8M |
| MAVERICK CAPITAL LTD | $229.3M | 2,150,762 | 2.03% | new | NEW |
| Qube Research & Technologies Ltd | $179.4M | 1,682,334 | 0.17% | 2q | +1032.8%+$163.5M |
| WESTFIELD CAPITAL MANAGEMENT CO LP | $173.7M | 1,629,561 | 0.57% | 8q | +11.0%+$17.2M |
| T. Rowe Price Investment Management, Inc. | $173.0M | 1,622,675 | 0.11% | new | NEW |
| Caption Management, LLC | $171.3M incl. $146.1M options CALL+PUT | 236,000 | 0.80% | 18q | HELD |
| Integral Health Asset Management, LLC | $170.6M | 1,600,000 | 6.74% | 11q | +6.7%+$10.7M |
| VANGUARD FIDUCIARY TRUST CO | $149.4M | 1,401,552 | 0.03% | 2q | +3.5%+$5.0M |
| Bellevue Group AG | $148.6M | 1,393,418 | 3.13% | 31q | +13787.0%+$147.5M |
| Balyasny Asset Management L.P. | $143.2M incl. $1.8M options CALL | 1,326,430 | 0.18% | 5q | +498.3%+$119.3M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $142.3M | 1,335,071 | 0.03% | 31q | +9.9%+$12.8M |
| Paradigm Biocapital Advisors LP | $141.4M | 1,325,977 | 2.65% | 2q | +5.7%+$7.6M |
| NORTHERN TRUST CORP | $140.2M | 1,315,325 | 0.02% | 31q | +1.6%+$2.3M |
| Bank of New York Mellon Corp | $140.0M | 1,312,756 | 0.02% | 31q | +4.0%+$5.3M |
| TWO SIGMA INVESTMENTS, LP | $133.3M incl. $853.0K options CALL+PUT | 1,242,222 | 0.10% | 16q | +424.1%+$107.9M |
| MORGAN STANLEY | $131.5M | 1,233,498 | 0.01% | 35q | -7.4%-$10.5M |
| Pictet Asset Management Holding SA | $129.8M | 1,220,353 | 0.12% | 12q | +10.7%+$12.6M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $129.4M | 1,213,963 | 0.02% | 31q | +13.5%+$15.4M |
| Hood River Capital Management LLC | $112.7M | 1,056,871 | 0.82% | 11q | +53.5%+$39.3M |
| BANK OF AMERICA CORP /DE/ | $109.1M | 1,023,114 | 0.01% | 31q | -31.9%-$51.1M |
| SEI INVESTMENTS CO | $108.3M | 1,015,870 | 0.10% | 31q | -27.2%-$40.5M |
| NWI MANAGEMENT LP | $108.1M | 1,014,000 | 5.00% | 8q | -50.0%-$108.1M |
| Castle Hook Partners LP | $105.9M | 993,310 | 0.49% | 5q | -21.8%-$29.5M |
| JANE STREET GROUP, LLC | $105.8M incl. $85.1M options CALL+PUT | 193,528 | 0.01% | 28q | +1597.5%+$99.5M |
| JENNISON ASSOCIATES LLC | $96.5M | 905,094 | 0.06% | 11q | +49.7%+$32.0M |
| Polar Capital Holdings Plc | $95.0M | 890,872 | 0.22% | 23q | +142.0%+$55.7M |
| FIL Ltd | $91.3M | 856,214 | 0.07% | 16q | +3.3%+$2.9M |
| PRINCIPAL FINANCIAL GROUP INC | $91.3M | 856,126 | 0.04% | 31q | -6.6%-$6.4M |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $90.6M | 850,000 | 0.13% | 12q | -5.6%-$5.3M |
| Fiera Capital Corp | $89.9M | 843,042 | 0.33% | 9q | -17.5%-$19.1M |
| Legal & General Group Plc | $88.1M | 826,431 | 0.02% | 31q | +5.0%+$4.2M |
| FRONTIER CAPITAL MANAGEMENT CO LLC | $84.8M | 795,242 | 0.79% | 10q | +69.4%+$34.7M |
| AMERICAN CENTURY COMPANIES INC | $81.0M | 759,735 | 0.04% | 30q | -17.9%-$17.7M |
| SAMLYN CAPITAL, LLC | $78.1M | 732,568 | 1.27% | 4q | +75.6%+$33.6M |
| TimesSquare Capital Management, LLC | $77.6M | 728,096 | 1.14% | 8q | +24.5%+$15.3M |
| Clearbridge Investments, LLC | $76.3M | 715,922 | 0.06% | 10q | +11.3%+$7.7M |
| ALLIANCEBERNSTEIN L.P. | $75.7M | 462,796 | 0.03% | 31q | -32.8%-$36.9M |
| HRT FINANCIAL LP | $75.7M incl. $2.1M options OPT | 709,681 | 0.14% | new | NEW |
| Ensign Peak Advisors, Inc | $74.9M | 702,951 | 0.12% | 19q | +40.7%+$21.7M |
| DEUTSCHE BANK AG\ | $73.6M | 690,590 | 0.02% | 34q | +22.8%+$13.7M |
| RAYMOND JAMES FINANCIAL INC | $70.4M | 660,601 | 0.02% | 7q | -14.8%-$12.2M |
| Squarepoint Ops LLC | $69.7M incl. $3.9M options CALL+PUT | 616,464 | 0.08% | 5q | +1468.0%+$65.2M |
| Affinity Asset Advisors, LLC | $69.3M | 650,000 | 3.13% | 9q | +35.4%+$18.1M |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | $67.2M | 629,831 | 0.20% | 26q | -30.2%-$29.1M |
| GW&K Investment Management, LLC | $67.1M | 629,760 | 0.52% | 23q | +1.1%+$715.6K |
| AQR CAPITAL MANAGEMENT LLC | $65.3M | 612,832 | 0.02% | 31q | -9.3%-$6.7M |
| Railway Pension Investments Ltd | $64.5M | 604,700 | 0.81% | new | NEW |
| Swiss National Bank | $63.3M | 593,512 | 0.03% | 31q | -5.2%-$3.5M |
| Nuveen, LLC | $63.1M | 591,844 | 0.02% | 6q | +10.7%+$6.1M |
| Artia Global Partners LP | $62.8M | 589,052 | 11.59% | 11q | -6.3%-$4.2M |
| EVENTIDE ASSET MANAGEMENT, LLC | $62.2M | 583,665 | 0.83% | 15q | +6.8%+$4.0M |
| Aberdeen Group plc | $61.6M | 577,437 | 0.09% | 11q | +108.4%+$32.0M |
| Davern Capital Partners, LP | $59.7M | 559,824 | 10.18% | 2q | +206.6%+$40.2M |
| Candriam S.C.A. | $59.1M | 555,131 | 0.27% | 25q | +38.2%+$16.3M |
| WELLINGTON MANAGEMENT GROUP LLP | $58.0M | 543,893 | 0.01% | 9q | +36.3%+$15.4M |
| Point72 Asset Management, L.P. | $57.5M incl. $223.9K options CALL+PUT | 536,997 | 0.06% | 5q | HELD |
| Long Focus Capital Management, LLC | $56.3M | 528,000 | 1.44% | 19q | +264.1%+$40.8M |
| TUDOR INVESTMENT CORP ET AL | $54.8M incl. $33.9M options CALL+PUT | 195,391 | 0.08% | 8q | HELD |
| MARSHALL WACE, LLP | $53.5M | 501,930 | 0.04% | 13q | +60.6%+$20.2M |
| Amundi | $52.0M | 487,525 | 0.01% | 7q | -39.4%-$33.8M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $50.7M | 475,307 | 0.05% | 18q | +1.6%+$805.3K |
| Bridgewater Associates, LP | $48.6M | 455,392 | 0.20% | 2q | +54.1%+$17.0M |
| Sumitomo Mitsui Trust Group, Inc. | $46.7M | 437,713 | 0.03% | 3q | -12.7%-$6.8M |
| Assenagon Asset Management S.A. | $46.5M | 436,540 | 0.03% | 19q | +590.1%+$39.8M |
| BNP PARIBAS FINANCIAL MARKETS | $44.9M incl. $2.1M options CALL+PUT | 400,765 | 0.02% | 15q | -33.7%-$22.8M |
| ROYAL BANK OF CANADA | $44.4M | 416,487 | 0.01% | 31q | -20.4%-$11.4M |
| VANGUARD ASSET MANAGEMENT, Ltd | $44.4M | 416,108 | 0.03% | 2q | +15.6%+$6.0M |
| Palo Alto Investors LP | $44.1M | 413,980 | 6.10% | 31q | HELD |
| DIMENSIONAL FUND ADVISORS LP | $43.5M | 408,388 | 0.01% | 9q | +1.9%+$798.1K |
| Eagle Health Investments LP | $41.0M | 384,130 | 6.79% | 9q | +71.3%+$17.0M |
| NEUBERGER BERMAN GROUP LLC | $40.4M | 378,816 | 0.03% | 21q | +39.9%+$11.5M |
| Prosight Management, LP | $40.0M | 375,609 | 6.90% | new | NEW |
| Invesco Ltd. | $39.3M | 368,261 | 0.00% | 30q | -94.3%-$655.1M |
| GATEWAY INVESTMENT ADVISERS LLC | $38.9M | 365,000 | 0.38% | 3q | HELD |
| Rock Springs Capital Management LP | $38.6M | 362,150 | 1.88% | 9q | +15.2%+$5.1M |
| ENVESTNET ASSET MANAGEMENT INC | $35.9M | 336,997 | 0.01% | 26q | +12.4%+$4.0M |
Showing the largest 100 of 673 reported holders.
What the company announced
Form 8-K filings from the last 120 days, showing only the items worth a reader's attention. Earnings releases, exhibit attachments and general disclosures are filed constantly and are left out. Filed is when the SEC received it; event is the date the company says the thing happened.
| Filed | Event date | What | Source |
|---|---|---|---|
| 2026-10-20 | 2026-10-16 | Directors or officers departed or appointed | filing |
| 2026-10-05 | 2026-10-05 | Directors or officers departed or appointed | filing |
What the insiders did
Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.
Officers and directors
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-08-10 | Adsett Roger | Chief Operating Officer | Sold | 239,850 | $32.0M |
| 2026-08-06 | Flammer Martina M.D. | Chief Medical Officer | Sold | 27,173 | $3.5M ×2 |
| 2026-09-09 | Brennan David R | Director | Sold | 25,000 | $3.1M |
| 2026-05-18 | Lewis William | Chair and CEO | Sold | 25,564 | $2.7M ×3 |
| 2026-06-25 | Lewis William | Chair and CEO | Sold | 21,398 | $2.2M ×5 |
| 2026-05-13 | Lewis William | Chair and CEO | Sold | 13,283 | $1.5M |
| 2026-07-06 | Flammer Martina M.D. | Chief Medical Officer | Sold | 12,302 | $1.4M ×2 |
| 2026-05-11 | Flammer Martina M.D. | Chief Medical Officer | Sold | 12,949 | $1.3M ×2 |
| 2026-07-09 | Lewis William | Chair and CEO | Sold | 10,699 | $1.3M ×3 |
| 2026-05-14 | Flammer Martina M.D. | Chief Medical Officer | Sold | 10,479 | $1.2M |
| 2026-07-23 | Lewis William | Chair and CEO | Sold | 10,700 | $1.1M ×2 |
| 2026-05-13 | Bonstein Sara | Chief Financial Officer | Sold | 8,272 | $961.0K |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 187 | $463.5M | 4,075,017 | 42 | 68 | 39 | 0.0% |
| Q2 2026 | 673 | $24.9B | 223,999,265 | 108 | 241 | 227 | 4.1% |
| Q1 2026 | 682 | $36.5B | 221,954,310 | 91 | 279 | 208 | 1.6% |
| Q4 2025 | 692 | $39.4B | 218,513,126 | 173 | 237 | 182 | 3.6% |
| Q3 2025 | 576 | $35.1B | 234,947,662 | 132 | 194 | 199 | 3.7% |
| Q2 2025 | 526 | $22.0B | 211,544,038 | 127 | 161 | 188 | 3.1% |
| Q1 2025 | 451 | $15.6B | 200,312,646 | 54 | 180 | 148 | 1.4% |
| Q4 2024 | 447 | $13.7B | 192,582,710 | 49 | 177 | 143 | 3.1% |
| Q3 2024 | 423 | $14.4B | 191,410,218 | 73 | 177 | 116 | 3.1% |
| Q2 2024 | 394 | $12.9B | 178,994,544 | 130 | 131 | 104 | 7.3% |
| Q1 2024 | 297 | $4.3B | 152,360,519 | 48 | 90 | 90 | 3.9% |
| Q4 2023 | 281 | $4.8B | 152,428,537 | 40 | 89 | 83 | 1.3% |
| Q3 2023 | 257 | $3.8B | 148,226,969 | 49 | 84 | 71 | 1.4% |
| Q2 2023 | 224 | $3.1B | 146,415,791 | 26 | 74 | 75 | 0.9% |
| Q1 2023 | 232 | $2.6B | 150,161,094 | 34 | 79 | 65 | 0.6% |
| Q4 2022 | 228 | $2.9B | 143,561,496 | 35 | 94 | 69 | 0.2% |
| Q3 2022 | 230 | $4.9B | 226,381,751 | 46 | 85 | 57 | 0.2% |
| Q2 2022 | 199 | $4.5B | 225,203,609 | 22 | 71 | 69 | 0.1% |
| Q1 2022 | 212 | $5.2B | 222,579,091 | 33 | 78 | 62 | 0.1% |
| Q4 2021 | 204 | $6.6B | 243,359,606 | 28 | 67 | 60 | 0.1% |
| Q3 2021 | 186 | $5.5B | 201,281,660 | 13 | 70 | 59 | 0.1% |
| Q2 2021 | 196 | $5.7B | 199,397,164 | 28 | 84 | 49 | 0.1% |
| Q1 2021 | 195 | $6.1B | 182,053,069 | 19 | 65 | 78 | 0.1% |
| Q4 2020 | 205 | $4.6B | 136,820,542 | 26 | 57 | 75 | 0.2% |
| Q3 2020 | 198 | $6.4B | 197,137,960 | 29 | 71 | 61 | 0.2% |
| Q2 2020 | 190 | $5.6B | 204,580,631 | 43 | 85 | 37 | 0.2% |
| Q1 2020 | 163 | $2.7B | 170,292,323 | 33 | 42 | 60 | 0.5% |
| Q4 2019 | 172 | $4.5B | 187,779,624 | 28 | 50 | 53 | 0.8% |
| Q3 2019 | 158 | $3.3B | 201,677,998 | 25 | 60 | 42 | 0.6% |
| Q2 2019 | 171 | $6.4B | 249,819,786 | 34 | 80 | 34 | 0.7% |
| Q1 2019 | 159 | $4.8B | 165,235,413 | 43 | 44 | 49 | 1.0% |
| Q4 2018 | 126 | $2.2B | 167,361,240 | 1 | 3 | 2 | 1.3% |
