DaveManuel.com · Institutional Ownership · Who Owns It
DISC MEDICINE INC (IRON)
Institutional ownership reported to the SEC as of Q2 2026, across 16 quarters.
225
Reporting holders
$3.2B
Reported value
112.4%
Of shares outstanding
0.8%
Calls
0.1%
Puts
+19
Holder change
Institutions report 43,152,488 shares against 38,392,844 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| FMR LLC | $358.0M | 4,894,473 | 0.02% | 15q | -12.4%-$50.6M |
| BlackRock, Inc. | $180.5M | 2,467,899 | 0.00% | 8q | +8.5%+$14.2M |
| RA CAPITAL MANAGEMENT, L.P. | $179.2M | 2,450,221 | 1.56% | 6q | HELD |
| JPMORGAN CHASE & CO | $139.9M | 1,875,795 | 0.01% | 13q | +36.8%+$37.6M |
| PRICE T ROWE ASSOCIATES INC /MD/ | $137.2M | 1,875,399 | 0.01% | 13q | +21.0%+$23.8M |
| WELLINGTON MANAGEMENT GROUP LLP | $127.4M | 1,741,351 | 0.02% | 13q | HELD |
| STATE STREET CORP | $120.6M | 1,648,836 | 0.00% | 15q | -2.9%-$3.6M |
| Vestal Point Capital, LP | $113.4M | 1,550,000 | 2.65% | 5q | +121.4%+$62.2M |
| Atlas Venture Life Science Advisors, LLC | $110.7M | 1,513,875 | 12.56% | 15q | HELD |
| VANGUARD CAPITAL MANAGEMENT LLC | $100.1M | 1,369,027 | 0.00% | 2q | HELD |
| Frazier Life Sciences Management, L.P. | $99.1M | 1,354,852 | 2.16% | 13q | HELD |
| TCG Crossover Management, LLC | $98.1M | 1,341,862 | 2.36% | 2q | HELD |
| BVF INC/IL | $84.4M | 1,153,612 | 2.16% | 3q | -9.3%-$8.7M |
| Woodline Partners LP | $70.1M | 958,281 | 0.22% | 9q | HELD |
| Siren, L.L.C. | $65.0M | 888,401 | 1.31% | 6q | -10.1%-$7.3M |
| Logos Global Management LP | $64.0M | 875,000 | 2.76% | 9q | +56.2%+$23.0M |
| Opaleye Management Inc. | $62.5M | 855,000 | 5.66% | 6q | +103.1%+$31.7M |
| GEODE CAPITAL MANAGEMENT, LLC | $57.8M | 789,724 | 0.00% | 15q | +6.1%+$3.3M |
| Assenagon Asset Management S.A. | $56.2M | 768,316 | 0.04% | 4q | +40.7%+$16.2M |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $48.1M | 657,000 | 0.50% | 13q | HELD |
| DIMENSIONAL FUND ADVISORS LP | $41.6M | 569,018 | 0.01% | 8q | +44.3%+$12.8M |
| Bellevue Group AG | $41.0M | 560,000 | 0.86% | 2q | +21.9%+$7.4M |
| Saturn V Capital Management LP | $38.4M | 524,730 | 5.50% | 11q | +16.6%+$5.5M |
| ARMISTICE CAPITAL, LLC | $33.6M | 460,000 | 0.41% | 8q | -14.2%-$5.6M |
| JENNISON ASSOCIATES LLC | $32.1M | 439,520 | 0.02% | 3q | -28.0%-$12.5M |
| Aberdeen Group plc | $32.0M | 438,174 | 0.04% | 5q | +16.7%+$4.6M |
| Palo Alto Investors LP | $30.5M | 416,646 | 4.21% | 5q | +3.7%+$1.1M |
| EVENTIDE ASSET MANAGEMENT, LLC | $28.9M | 395,651 | 0.39% | 6q | HELD |
| Pictet Asset Management Holding SA | $28.2M | 385,375 | 0.03% | 4q | HELD |
| LOOMIS SAYLES & CO L P | $27.9M | 381,864 | 0.04% | 3q | +20.4%+$4.7M |
| Foresite Capital Management V, LLC | $27.4M | 374,069 | 7.55% | 15q | HELD |
| ORBIMED ADVISORS LLC | $26.2M | 357,535 | 0.48% | 15q | -66.5%-$51.9M |
| BAKER BROS. ADVISORS LP | $25.6M | 349,657 | 0.13% | 7q | HELD |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $20.6M | 281,937 | 0.00% | 2q | +14.0%+$2.5M |
| Octagon Capital Advisors LP | $19.7M | 270,000 | 1.78% | 2q | HELD |
| NORTHERN TRUST CORP | $19.4M | 264,990 | 0.00% | 13q | +7.2%+$1.3M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $18.8M | 257,382 | 0.00% | 13q | +2.5%+$452.5K |
| CITADEL ADVISORS LLC | $17.7M incl. $2.4M options CALL+PUT | 209,308 | 0.00% | 15q | +113.7%+$9.4M |
| Checkpoint Capital L.P. | $17.6M | 240,125 | 4.51% | 8q | -16.2%-$3.4M |
| VANGUARD FIDUCIARY TRUST CO | $16.5M | 225,198 | 0.00% | 2q | +3.6%+$567.7K |
| Bank of New York Mellon Corp | $15.0M | 204,727 | 0.00% | 13q | HELD |
| BNP PARIBAS FINANCIAL MARKETS | $13.5M | 184,695 | 0.00% | 7q | +44.6%+$4.2M |
| Catalio Capital Management, LP | $11.7M | 159,384 | 2.19% | 5q | +29.6%+$2.7M |
| Caption Management, LLC | $11.0M CALL | options only | 0.05% | 2q | OPTIONS |
| Sofinnova Investments, Inc. | $10.7M | 146,239 | 0.55% | 10q | +86.7%+$5.0M |
| Bain Capital Life Sciences Investors, LLC | $10.3M | 141,234 | 0.61% | 2q | HELD |
| TWO SIGMA INVESTMENTS, LP | $10.0M | 136,750 | 0.01% | new | NEW |
| BANK OF AMERICA CORP /DE/ | $9.9M | 135,111 | 0.00% | 15q | -19.0%-$2.3M |
| Alyeska Investment Group, L.P. | $9.1M | 125,000 | 0.02% | 3q | HELD |
| Ensign Peak Advisors, Inc | $8.9M | 122,111 | 0.01% | 13q | -36.2%-$5.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $8.3M | 114,109 | 0.00% | 10q | +2.9%+$235.4K |
| UBS Group AG | $8.1M | 110,971 | 0.00% | 15q | +12.5%+$903.3K |
| Trexquant Investment LP | $7.9M | 107,699 | 0.05% | new | NEW |
| KENNEDY CAPITAL MANAGEMENT LLC | $7.8M | 106,769 | 0.14% | 4q | -1.4%-$111.0K |
| MILLENNIUM MANAGEMENT LLC | $7.8M | 106,248 | 0.00% | 7q | +27.6%+$1.7M |
| GOLDMAN SACHS GROUP INC | $7.1M | 97,383 | 0.00% | 12q | -84.8%-$39.7M |
| MORGAN STANLEY | $6.7M | 91,595 | 0.00% | 15q | -2.8%-$195.2K |
| HRT FINANCIAL LP | $6.6M | 90,822 | 0.01% | new | NEW |
| SILVERARC CAPITAL MANAGEMENT, LLC | $6.1M | 82,800 | 0.63% | 2q | -57.8%-$8.3M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $6.0M incl. $5.7M options CALL+PUT | 2,914 | 0.00% | 11q | -81.1%-$25.6M |
| RAYMOND JAMES FINANCIAL INC | $5.7M | 77,980 | 0.00% | 7q | +74.5%+$2.4M |
| Squarepoint Ops LLC | $5.5M | 75,872 | 0.01% | 4q | +139.3%+$3.2M |
| DNB Asset Management AS | $5.3M | 73,127 | 0.01% | 5q | -24.4%-$1.7M |
| iA Global Asset Management Inc. | $4.8M | 66,023 | 0.06% | 5q | HELD |
| Casdin Capital, LLC | $4.8M | 65,000 | 0.24% | 2q | HELD |
| SPHERA FUNDS MANAGEMENT LTD. | $4.6M | 63,538 | 0.61% | 2q | +18.7%+$731.4K |
| Nuveen, LLC | $4.4M | 60,357 | 0.00% | 6q | +17.5%+$656.6K |
| PEAK6 LLC | $4.4M CALL | options only | 0.01% | new | OPTIONS |
| KVP Capital Advisors, LP | $4.3M | 58,250 | 3.13% | 3q | HELD |
| MOORE CAPITAL MANAGEMENT, LP | $4.2M | 57,796 | 0.06% | 2q | HELD |
| XTX Topco Ltd | $4.1M | 56,710 | 0.05% | 3q | +64.8%+$1.6M |
| NEXTBio Capital Management LP | $3.9M | 52,655 | 1.77% | 3q | HELD |
| ALGERT GLOBAL LLC | $3.8M | 51,850 | 0.04% | 2q | +128.6%+$2.1M |
| ExodusPoint Capital Management, LP | $3.8M | 51,623 | 0.02% | new | NEW |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $3.7M | 50,000 | 0.00% | 11q | -1.9%-$71.4K |
| Burkehill Global Management, LP | $3.7M | 50,000 | 0.13% | 3q | HELD |
| Brevan Howard Capital Management LP | $3.7M | 49,996 | 0.03% | 3q | +54.3%+$1.3M |
| Swiss National Bank | $3.6M | 49,800 | 0.00% | 12q | +3.8%+$131.7K |
| AMERIPRISE FINANCIAL INC | $3.4M | 45,874 | 0.00% | 7q | HELD |
| Atle Fund Management AB | $3.2M | 43,682 | 0.86% | 5q | -59.3%-$4.6M |
| Quadrature Capital Ltd | $3.1M | 42,419 | 0.03% | new | NEW |
| Invesco Ltd. | $3.1M | 42,057 | 0.00% | 13q | +37.3%+$835.2K |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $2.9M | 39,360 | 0.00% | 13q | +14.5%+$364.1K |
| ALPS ADVISORS INC | $2.8M | 38,565 | 0.01% | 13q | +24.2%+$549.1K |
| CITIGROUP INC | $2.8M | 38,317 | 0.00% | 15q | +394.9%+$2.2M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $2.8M | 38,262 | 0.00% | 5q | -4.1%-$120.5K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $2.7M | 36,634 | 0.00% | 6q | -3.6%-$100.3K |
| RHUMBLINE ADVISERS | $2.6M | 35,844 | 0.00% | 13q | +8.4%+$203.8K |
| LAZARD ASSET MANAGEMENT LLC | $2.6M | 35,034 | 0.00% | 3q | -11.1%-$319.3K |
| SEVEN GRAND MANAGERS, LLC | $2.6M | 35,000 | 0.10% | 3q | HELD |
| MARSHALL WACE, LLP | $2.5M | 34,394 | 0.00% | new | NEW |
| Jump Financial, LLC | $2.4M | 32,549 | 0.02% | 2q | -60.2%-$3.6M |
| JANE STREET GROUP, LLC | $2.4M incl. $1.2M options CALL+PUT | 16,011 | 0.00% | 4q | HELD |
| BANK OF MONTREAL /CAN/ | $2.4M | 32,308 | 0.00% | 6q | +12.3%+$258.5K |
| DEUTSCHE BANK AG\ | $2.2M | 30,643 | 0.00% | 13q | +25.6%+$456.5K |
| ALLIANCEBERNSTEIN L.P. | $2.2M | 34,670 | 0.00% | 13q | +41.3%+$647.7K |
| RTW INVESTMENTS, LP | $2.2M | 30,000 | 0.02% | 3q | HELD |
| Squadron Capital Management LLC | $2.2M CALL | options only | 0.68% | new | OPTIONS |
| VICTORY CAPITAL MANAGEMENT INC | $2.1M | 29,117 | 0.00% | 12q | HELD |
| WELLS FARGO & COMPANY/MN | $2.1M | 28,924 | 0.00% | 14q | +96.9%+$1.0M |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-10-26 | 13D/A | AI DMI LLCwith 3 co-filers | 6.6% |
What the company announced
Form 8-K filings from the last 120 days, showing only the items worth a reader's attention. Earnings releases, exhibit attachments and general disclosures are filed constantly and are left out. Filed is when the SEC received it; event is the date the company says the thing happened.
| Filed | Event date | What | Source |
|---|---|---|---|
| 2026-10-22 | 2026-10-19 | Material agreement entered | filing |
What the insiders did
Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.
Officers and directors
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-09-02 | Bitterman Kevin | Director | Sold | 49,164 | $3.9M ×6 |
| 2026-08-17 | Quisel John D | Chief Executive Officer | Sold | 33,000 | $2.6M ×3 |
| 2026-07-13 | Quisel John D | Chief Executive Officer | Sold | 33,000 | $2.5M ×3 |
| 2026-06-18 | Quisel John D | Chief Executive Officer | Sold | 34,000 | $2.4M ×3 |
| 2026-10-21 | Bitterman Kevin | Director | Sold | 25,519 | $2.0M ×3 |
| 2026-09-11 | Bitterman Kevin | Director | Sold | 27,136 | $1.9M |
| 2026-06-16 | Yu Jonathan Yen-Wen | Chief Operating Officer | Sold | 18,612 | $1.3M ×2 |
| 2026-10-19 | Bitterman Kevin | Director | Sold | 10,994 | $879.2K ×3 |
| 2026-08-25 | Yu Jonathan Yen-Wen | Chief Operating Officer | Sold | 8,796 | $731.1K |
| 2026-06-22 | Yu Jonathan Yen-Wen | Chief Operating Officer | Sold | 9,700 | $704.8K |
| 2026-06-18 | Khara Rahul | Chief Legal Officer | Sold | 7,500 | $526.7K ×3 |
| 2026-10-20 | Bitterman Kevin | Director | Sold | 5,312 | $424.7K ×3 |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 30 | $81.3M | 1,241,469 | 8 | 13 | 5 | 0.0% |
| Q2 2026 | 225 | $3.2B | 43,152,488 | 40 | 74 | 58 | 1.0% |
| Q1 2026 | 206 | $2.7B | 41,898,154 | 42 | 75 | 42 | 1.0% |
| Q4 2025 | 199 | $3.1B | 38,292,547 | 38 | 84 | 48 | 0.4% |
| Q3 2025 | 170 | $2.3B | 34,973,153 | 27 | 58 | 42 | 0.2% |
| Q2 2025 | 153 | $1.8B | 34,092,016 | 26 | 66 | 37 | 1.3% |
| Q1 2025 | 158 | $1.7B | 33,160,010 | 28 | 73 | 29 | 0.1% |
| Q4 2024 | 153 | $1.7B | 26,576,603 | 31 | 47 | 43 | 0.4% |
| Q3 2024 | 131 | $1.4B | 27,473,235 | 24 | 56 | 27 | 0.1% |
| Q2 2024 | 120 | $1.3B | 28,665,791 | 27 | 54 | 28 | 0.2% |
| Q1 2024 | 136 | $1.5B | 22,677,036 | 35 | 55 | 29 | 6.0% |
| Q4 2023 | 113 | $1.2B | 20,325,583 | 29 | 39 | 28 | 2.0% |
| Q3 2023 | 94 | $950.3M | 19,921,838 | 19 | 38 | 18 | 1.5% |
| Q2 2023 | 92 | $2.7B | 19,115,397 | 58 | 18 | 11 | 69.1% |
| Q1 2023 | 45 | $312.9M | 14,764,134 | 12 | 15 | 6 | 0.0% |
| Q4 2022 | 32 | $216.7M | 10,800,037 | 31 | 0 | 0 | 0.9% |