DaveManuel.com · Institutional Ownership · Who Owns It
LEXICON PHARMACEUTICALS INC (LXRX)
Institutional ownership reported to the SEC as of Q2 2026, across 32 quarters.
151
Reporting holders
$880.4M
Reported value
81.9%
Of shares outstanding
0.6%
Calls
0.0%
Puts
+14
Holder change
Institutions report 364,620,815 shares against 444,955,934 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| Artal Group S.A. | $420.4M | 175,156,062 | 45.15% | 31q | +13.2%+$49.0M |
| FMR LLC | $124.3M | 51,782,045 | 0.01% | 31q | +14.9%+$16.1M |
| Siren, L.L.C. | $106.3M | 44,303,518 | 2.15% | 8q | HELD |
| Sessa Capital IM, L.P. | $45.5M | 18,960,836 | 0.76% | 5q | +5.8%+$2.5M |
| BlackRock, Inc. | $41.6M | 17,348,741 | 0.00% | 8q | +422.2%+$33.7M |
| VANGUARD CAPITAL MANAGEMENT LLC | $23.8M | 9,901,208 | 0.00% | 2q | +4.0%+$916.9K |
| Point72 Asset Management, L.P. | $19.8M | 8,251,325 | 0.02% | 3q | +5.6%+$1.0M |
| GEODE CAPITAL MANAGEMENT, LLC | $15.0M | 6,244,372 | 0.00% | 31q | +97.0%+$7.4M |
| STATE STREET CORP | $11.8M | 4,917,769 | 0.00% | 31q | +410.1%+$9.5M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $5.7M | 2,357,749 | 0.00% | 2q | +331.3%+$4.3M |
| CITADEL ADVISORS LLC | $4.8M incl. $929.3K options CALL+PUT | 1,601,182 | 0.00% | 31q | +46.2%+$1.5M |
| NORTHERN TRUST CORP | $4.7M | 1,968,619 | 0.00% | 31q | +298.0%+$3.5M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $4.7M | 1,956,775 | 0.00% | 31q | +49.2%+$1.5M |
| VANGUARD FIDUCIARY TRUST CO | $3.9M | 1,634,571 | 0.00% | 2q | +22.7%+$725.5K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $3.3M incl. $1.6M options CALL+PUT | 696,776 | 0.00% | 31q | -67.2%-$6.8M |
| Ishara Investments LP | $3.1M | 1,271,000 | 2.24% | 3q | +40.9%+$885.6K |
| MILLENNIUM MANAGEMENT LLC | $2.7M | 1,134,229 | 0.00% | 6q | -77.1%-$9.1M |
| RENAISSANCE TECHNOLOGIES LLC | $2.7M | 1,127,000 | 0.00% | 4q | -29.6%-$1.1M |
| MACKENZIE FINANCIAL CORP | $2.3M | 963,354 | 0.00% | 2q | +24.7%+$457.6K |
| ADAR1 Capital Management, LLC | $1.8M | 750,000 | 0.08% | 2q | HELD |
| ACADIAN ASSET MANAGEMENT LLC | $1.7M | 696,617 | 0.00% | 4q | +56.4%+$601.1K |
| UBS Group AG | $1.6M | 684,713 | 0.00% | 31q | -72.4%-$4.3M |
| GROUP ONE TRADING LLC | $1.6M incl. $1.2M options CALL+PUT | 175,013 | 0.00% | 31q | -5.4%-$90.1K |
| TWO SIGMA INVESTMENTS, LP | $1.5M | 643,444 | 0.00% | 5q | -46.4%-$1.3M |
| Nuveen, LLC | $1.4M | 586,664 | 0.00% | new | NEW |
| JANE STREET GROUP, LLC | $1.4M CALL | options only | 0.00% | 5q | OPTIONS |
| Bank of New York Mellon Corp | $1.4M | 568,706 | 0.00% | 31q | +1971.1%+$1.3M |
| Invesco Ltd. | $1.2M | 508,071 | 0.00% | 25q | -0.8%-$10.5K |
| GOLDMAN SACHS GROUP INC | $1.2M | 485,546 | 0.00% | 31q | -54.6%-$1.4M |
| Compagnie Lombard Odier SCmA | $1.2M | 480,000 | 0.01% | 31q | -5.9%-$72.0K |
| BANK OF AMERICA CORP /DE/ | $1.0M | 421,299 | 0.00% | 31q | -19.9%-$251.5K |
| GSA CAPITAL PARTNERS LLP | $953.0K | 397,219 | 0.06% | 6q | -57.3%-$1.3M |
| BARCLAYS PLC | $930.0K | 387,483 | 0.00% | 31q | +267.3%+$676.8K |
| XTX Topco Ltd | $858.9K | 357,877 | 0.01% | 6q | +13.8%+$103.8K |
| Janney Montgomery Scott LLC | $709.0K | 295,548 | 0.00% | new | NEW |
| CANADA PENSION PLAN INVESTMENT BOARD | $619.0K | 257,900 | 0.00% | new | NEW |
| RHUMBLINE ADVISERS | $616.5K | 256,885 | 0.00% | 4q | HELD |
| DEUTSCHE BANK AG\ | $594.1K | 247,528 | 0.00% | new | NEW |
| WELLS FARGO & COMPANY/MN | $553.1K | 230,470 | 0.00% | 14q | +2870.0%+$534.5K |
| PRICE T ROWE ASSOCIATES INC /MD/ | $491.0K | 204,391 | 0.00% | new | NEW |
| WELLINGTON MANAGEMENT GROUP LLP | $431.3K | 179,700 | 0.00% | new | NEW |
| CITIGROUP INC | $420.5K | 175,205 | 0.00% | 31q | +5.3%+$21.1K |
| Virtus Investment Advisers, LLC | $409.0K | 170,415 | 0.10% | new | NEW |
| Headlands Technologies LLC | $401.3K | 167,198 | 0.04% | 4q | -12.6%-$57.9K |
| Ikarian Capital, LLC | $395.2K | 164,674 | 0.04% | 7q | HELD |
| Quarry LP | $374.8K | 156,186 | 0.03% | 3q | +42.0%+$110.8K |
| MetLife Investment Management, LLC | $351.4K | 146,410 | 0.00% | new | NEW |
| MORGAN STANLEY | $319.0K | 132,902 | 0.00% | 35q | -39.6%-$208.7K |
| PANAGORA ASSET MANAGEMENT INC | $316.9K | 132,042 | 0.00% | new | NEW |
| JPMORGAN CHASE & CO | $290.0K | 109,839 | 0.00% | new | NEW |
| State of Wyoming | $285.8K | 119,090 | 0.03% | 4q | +1004.8%+$259.9K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $273.9K | 114,114 | 0.00% | new | NEW |
| Cornerstone Investment Partners, LLC | $273.0K | 113,739 | 0.01% | new | NEW |
| Cerity Partners LLC | $236.2K | 98,400 | 0.00% | 10q | -10.9%-$28.9K |
| ALGERT GLOBAL LLC | $221.2K | 92,150 | 0.00% | new | NEW |
| BANK OF NOVA SCOTIA | $207.9K | 86,607 | 0.00% | 2q | +17.5%+$31.0K |
| LPL Financial LLC | $203.8K | 84,916 | 0.00% | 18q | +21.7%+$36.3K |
| SIMPLEX TRADING, LLC | $199.3K incl. $178.8K options CALL+PUT | 8,540 | 0.00% | 21q | HELD |
| Vanguard Global Advisers, LLC | $187.1K | 77,946 | 0.00% | 2q | -16.8%-$37.7K |
| AQR CAPITAL MANAGEMENT LLC | $180.6K | 75,230 | 0.00% | 6q | -21.8%-$50.4K |
| Police & Firemen's Retirement System of New Jersey | $176.2K | 73,402 | 0.00% | new | NEW |
| UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO | $171.4K | 71,427 | 0.02% | 30q | +100.0%+$85.7K |
| PRUDENTIAL FINANCIAL INC | $171.2K | 71,345 | 0.00% | 4q | +111.1%+$90.1K |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $167.4K | 69,747 | 0.00% | new | NEW |
| NEW YORK STATE COMMON RETIREMENT FUND | $164.2K | 68,400 | 0.00% | new | NEW |
| TWO SIGMA SECURITIES, LLC | $159.3K | 66,375 | 0.01% | new | NEW |
| SEI INVESTMENTS CO | $153.4K | 63,937 | 0.00% | new | NEW |
| Straight Path Wealth Management | $150.4K | 62,666 | 0.04% | 6q | HELD |
| R Squared Ltd | $132.0K | 54,985 | 0.07% | 5q | -18.6%-$30.1K |
| Vanguard Personalized Indexing Management, LLC | $130.4K | 54,334 | 0.00% | 11q | -1.1%-$1.5K |
| Fortis Group Advisors, LLC | $120.0K | 50,000 | 0.02% | 6q | HELD |
| Schonfeld Strategic Advisors LLC | $118.6K | 49,435 | 0.00% | 10q | -34.2%-$61.6K |
| SCOTIA CAPITAL INC. | $117.3K | 48,871 | 0.00% | 2q | -69.4%-$266.3K |
| PROFUND ADVISORS LLC | $116.6K | 48,586 | 0.00% | new | NEW |
| VOYA INVESTMENT MANAGEMENT LLC | $114.7K | 47,771 | 0.00% | new | NEW |
| AXQ CAPITAL, LP | $109.7K | 45,727 | 0.01% | 2q | +126.9%+$61.4K |
| BOOTHBAY FUND MANAGEMENT, LLC | $106.4K | 44,315 | 0.00% | 7q | HELD |
| ALLIANCEBERNSTEIN L.P. | $105.8K | 67,800 | 0.00% | new | NEW |
| WINTON GROUP Ltd | $103.7K | 43,200 | 0.00% | 2q | +69.4%+$42.5K |
| INTECH INVESTMENT MANAGEMENT LLC | $102.0K | 42,491 | 0.00% | new | NEW |
| LMR Partners LLP | $98.6K | 41,091 | 0.00% | 2q | +76.3%+$42.7K |
| BANK OF MONTREAL /CAN/ | $96.0K | 40,000 | 0.00% | 10q | -42.9%-$72.0K |
| BNP PARIBAS FINANCIAL MARKETS | $90.7K | 37,780 | 0.00% | 31q | +115.3%+$48.6K |
| Rafferty Asset Management, LLC | $81.8K | 34,090 | 0.00% | new | NEW |
| ProShare Advisors LLC | $78.2K | 32,588 | 0.00% | new | NEW |
| Leonteq Securities AG | $72.0K | 30,000 | 0.00% | 3q | HELD |
| Pathstone Holdings, LLC | $71.9K | 29,969 | 0.00% | 11q | +0.7% |
| PINNACLE ASSOCIATES LTD | $69.6K | 29,015 | 0.00% | 31q | HELD |
| SECURITY NATIONAL BANK OF SIOUX CITY IOWA /IA/ | $64.0K | 26,650 | 0.03% | 3q | HELD |
| VICTORY CAPITAL MANAGEMENT INC | $58.1K | 24,223 | 0.00% | 23q | +6.8%+$3.7K |
| Legal & General Group Plc | $58.0K | 24,185 | 0.00% | new | NEW |
| XPONANCE LLC | $57.0K | 23,763 | 0.00% | new | NEW |
| Graham Capital Management, L.P. | $56.5K | 23,541 | 0.00% | 3q | -30.8%-$25.2K |
| Ameritas Investment Partners, Inc. | $55.2K | 22,986 | 0.00% | new | NEW |
| D. E. Shaw & Co., Inc. | $53.3K | 22,200 | 0.00% | new | NEW |
| Quadrature Capital Ltd | $52.8K | 21,998 | 0.00% | 4q | -80.1%-$212.1K |
| TIAA-CREF INDIVIDUAL & INSTITUTIONAL SERVICES, LLC | $48.0K | 20,000 | 0.00% | 2q | HELD |
| WEDBUSH SECURITIES INC | $48.0K | 20,000 | 0.00% | 10q | -51.0%-$50.0K |
| DIKER MANAGEMENT LLC | $48.0K | 20,000 | 0.04% | 2q | HELD |
| Invera Wealth Advisors, LLC | $48.0K | 20,000 | 0.03% | 6q | HELD |
Showing the largest 100 of 151 reported holders.
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 24 | $1.6M | 846,586 | 3 | 4 | 5 | 0.0% |
| Q2 2026 | 151 | $880.4M | 364,620,815 | 44 | 36 | 37 | 0.6% |
| Q1 2026 | 137 | $508.1M | 323,381,155 | 26 | 41 | 26 | 0.7% |
| Q4 2025 | 124 | $300.9M | 260,426,942 | 20 | 28 | 41 | 0.5% |
| Q3 2025 | 124 | $348.7M | 255,169,806 | 19 | 25 | 41 | 1.2% |
| Q2 2025 | 124 | $244.6M | 257,058,083 | 27 | 29 | 37 | 0.4% |
| Q1 2025 | 129 | $122.9M | 265,791,429 | 32 | 33 | 32 | 0.3% |
| Q4 2024 | 130 | $220.8M | 297,672,445 | 22 | 42 | 23 | 0.3% |
| Q3 2024 | 136 | $455.8M | 288,706,685 | 23 | 44 | 21 | 0.6% |
| Q2 2024 | 126 | $479.8M | 281,362,359 | 23 | 45 | 21 | 1.0% |
| Q1 2024 | 120 | $434.8M | 173,438,973 | 34 | 29 | 32 | 3.6% |
| Q4 2023 | 105 | $286.9M | 186,855,715 | 25 | 28 | 22 | 0.3% |
| Q3 2023 | 112 | $206.6M | 188,829,535 | 9 | 45 | 30 | 0.4% |
| Q2 2023 | 122 | $440.1M | 191,356,388 | 28 | 52 | 20 | 0.4% |
| Q1 2023 | 103 | $367.3M | 150,871,086 | 13 | 37 | 33 | 0.2% |
| Q4 2022 | 102 | $280.9M | 146,854,941 | 10 | 31 | 34 | 0.1% |
| Q3 2022 | 91 | $393.4M | 163,768,796 | 18 | 38 | 19 | 0.1% |
| Q2 2022 | 85 | $240.3M | 128,835,880 | 4 | 25 | 26 | 0.3% |
| Q1 2022 | 100 | $272.0M | 129,980,404 | 6 | 28 | 37 | 0.1% |
| Q4 2021 | 108 | $3.7B | 948,565,905 | 21 | 33 | 28 | 0.0% |
| Q3 2021 | 93 | $4.9B | 1,012,127,157 | 6 | 28 | 34 | 0.0% |
| Q2 2021 | 107 | $1.6B | 346,975,168 | 26 | 40 | 23 | 0.3% |
| Q1 2021 | 108 | $3.1B | 531,391,061 | 25 | 29 | 28 | 0.1% |
| Q4 2020 | 105 | $423.6M | 122,112,166 | 27 | 23 | 30 | 1.4% |
| Q3 2020 | 91 | $150.5M | 104,241,949 | 5 | 28 | 27 | 0.3% |
| Q2 2020 | 106 | $305.8M | 124,157,286 | 19 | 36 | 22 | 0.1% |
| Q1 2020 | 106 | $207.9M | 106,327,895 | 20 | 34 | 26 | 0.3% |
| Q4 2019 | 114 | $452.4M | 108,365,578 | 24 | 32 | 28 | 0.6% |
| Q3 2019 | 102 | $314.6M | 103,610,601 | 16 | 19 | 28 | 0.9% |
| Q2 2019 | 109 | $773.4M | 122,008,965 | 8 | 30 | 33 | 0.8% |
| Q1 2019 | 119 | $675.5M | 120,175,942 | 14 | 36 | 33 | 1.0% |
| Q4 2018 | 119 | $794.6M | 119,216,141 | 3 | 2 | 2 | 0.4% |