DaveManuel.com · Institutional Ownership · Who Owns It
MADRIGAL PHARMACEUTICALS INC (MDGL)
Institutional ownership reported to the SEC as of Q2 2026, across 32 quarters.
422
Reporting holders
$13.4B
Reported value
102.6%
Of shares outstanding
3.4%
Calls
1.9%
Puts
+34
Holder change
Institutions report 23,715,178 shares against 23,104,126 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | $1.2B | 2,143,131 | 5.77% | 31q | HELD |
| RTW INVESTMENTS, LP | $1.1B | 1,993,687 | 9.14% | 13q | HELD |
| Jupiter Topco LLC | $1.0B | 1,936,099 | 0.42% | new | FIRST |
| Avoro Capital Advisors LLC | $984.4M | 1,833,333 | 8.84% | 31q | +0.8%+$8.1M |
| PAULSON & CO. INC. | $719.5M | 1,340,020 | 27.94% | 13q | -3.7%-$28.0M |
| BlackRock, Inc. | $644.8M | 1,200,770 | 0.01% | 8q | -23.0%-$192.9M |
| VANGUARD CAPITAL MANAGEMENT LLC | $448.7M | 835,668 | 0.01% | 2q | +1.0%+$4.6M |
| WELLINGTON MANAGEMENT GROUP LLP | $443.4M | 825,714 | 0.08% | 8q | +18.8%+$70.2M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $419.8M | 781,731 | 0.02% | 2q | -7.1%-$31.9M |
| CITADEL ADVISORS LLC | $369.5M incl. $97.1M options CALL+PUT | 507,233 | 0.04% | 31q | +11.8%+$38.9M |
| STATE STREET CORP | $283.0M | 527,057 | 0.01% | 31q | -13.5%-$44.3M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $240.0M incl. $160.2M options CALL+PUT | 148,610 | 0.02% | 31q | +568.9%+$204.1M |
| UBS Group AG | $215.7M | 401,708 | 0.03% | 31q | +241.1%+$152.5M |
| GEODE CAPITAL MANAGEMENT, LLC | $201.3M | 374,880 | 0.01% | 31q | -17.8%-$43.5M |
| FMR LLC | $191.3M | 356,201 | 0.01% | 31q | -30.4%-$83.5M |
| JANE STREET GROUP, LLC | $190.5M incl. $87.7M options CALL+PUT | 191,541 | 0.02% | 15q | +434.5%+$154.9M |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | $174.0M | 324,123 | 0.52% | 7q | -4.8%-$8.8M |
| Invesco Ltd. | $161.9M | 301,435 | 0.01% | 26q | -8.5%-$15.1M |
| ARMISTICE CAPITAL, LLC | $154.6M | 288,000 | 1.89% | 30q | +8.9%+$12.6M |
| LORD, ABBETT & CO. LLC | $151.2M | 281,500 | 0.43% | 7q | +16.0%+$20.8M |
| Assenagon Asset Management S.A. | $133.4M | 248,428 | 0.08% | 3q | +1449.5%+$124.8M |
| GOLDMAN SACHS GROUP INC | $132.2M | 246,280 | 0.01% | 31q | -11.2%-$16.7M |
| Polar Capital Holdings Plc | $131.2M | 244,274 | 0.31% | 10q | -15.6%-$24.2M |
| AMERIPRISE FINANCIAL INC | $124.1M | 231,205 | 0.03% | 15q | +135.5%+$71.4M |
| NORGES BANK | $114.8M | 213,886 | 0.01% | 30q | +8.9%+$9.4M |
| Artisan Partners Limited Partnership | $112.9M | 210,205 | 0.18% | 24q | +14.5%+$14.3M |
| Pictet Asset Management Holding SA | $103.5M | 192,896 | 0.10% | 12q | +3.0%+$3.0M |
| PRICE T ROWE ASSOCIATES INC /MD/ | $100.5M | 187,226 | 0.01% | 31q | -42.9%-$75.6M |
| ALLIANCEBERNSTEIN L.P. | $99.2M | 189,458 | 0.03% | 31q | +51.0%+$33.5M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $99.0M | 184,324 | 0.01% | 31q | -14.9%-$17.4M |
| Caption Management, LLC | $98.4M CALL+PUT | options only | 0.46% | 2q | OPTIONS |
| TORONTO DOMINION BANK | $97.4M | 181,432 | 0.11% | 2q | +39.1%+$27.4M |
| Rock Springs Capital Management LP | $94.0M | 174,999 | 4.59% | 31q | +2.3%+$2.1M |
| Hood River Capital Management LLC | $90.8M | 169,084 | 0.66% | 7q | -32.2%-$43.2M |
| D. E. Shaw & Co., Inc. | $87.1M incl. $68.3M options CALL+PUT | 35,071 | 0.04% | 23q | +16.4%+$12.3M |
| Holocene Advisors, LP | $82.1M | 152,924 | 0.19% | new | NEW |
| Point72 Asset Management, L.P. | $76.6M incl. $3.0M options CALL+PUT | 137,029 | 0.08% | 6q | -39.2%-$49.5M |
| MORGAN STANLEY | $74.6M | 139,009 | 0.00% | 35q | -27.3%-$28.1M |
| BANK OF AMERICA CORP /DE/ | $72.0M | 134,036 | 0.00% | 31q | -29.3%-$29.8M |
| Bank of New York Mellon Corp | $69.0M | 128,520 | 0.01% | 31q | -5.4%-$4.0M |
| Woodline Partners LP | $67.6M | 125,899 | 0.21% | 10q | HELD |
| VANGUARD FIDUCIARY TRUST CO | $65.3M | 121,583 | 0.01% | 2q | -5.1%-$3.5M |
| MILLENNIUM MANAGEMENT LLC | $63.6M incl. $20.0M options CALL+PUT | 81,196 | 0.02% | 17q | +98.8%+$31.6M |
| Clearbridge Investments, LLC | $58.7M | 109,325 | 0.05% | 2q | +347.2%+$45.6M |
| Erste Asset Management GmbH | $58.1M | 110,210 | 0.45% | 15q | -31.2%-$26.4M |
| MARSHALL WACE, LLP | $54.7M | 101,859 | 0.04% | 9q | +365.1%+$42.9M |
| Fiera Capital Corp | $53.6M | 99,857 | 0.19% | 9q | -42.6%-$39.8M |
| AMERICAN CENTURY COMPANIES INC | $53.4M | 99,396 | 0.02% | 14q | -39.4%-$34.7M |
| NORTHERN TRUST CORP | $52.9M | 98,510 | 0.01% | 31q | -34.0%-$27.2M |
| NEW YORK STATE COMMON RETIREMENT FUND | $50.9M | 94,743 | 0.06% | 31q | +26.1%+$10.5M |
| WESTFIELD CAPITAL MANAGEMENT CO LP | $50.4M | 93,931 | 0.16% | 2q | -0.9%-$473.6K |
| 683 Capital Management, LLC | $48.3M PUT | options only | 2.37% | 14q | OPTIONS |
| HRT FINANCIAL LP | $45.4M | 84,634 | 0.08% | new | NEW |
| DEUTSCHE BANK AG\ | $45.1M | 83,916 | 0.01% | 34q | -14.4%-$7.6M |
| ALKEON CAPITAL MANAGEMENT LLC | $43.0M | 80,000 | 0.06% | 4q | HELD |
| Balyasny Asset Management L.P. | $42.4M | 79,011 | 0.05% | new | NEW |
| Driehaus Capital Management LLC | $41.9M | 78,094 | 0.24% | 4q | -29.6%-$17.6M |
| CITIGROUP INC | $39.3M incl. $19.3M options CALL+PUT | 37,255 | 0.01% | 31q | +45.6%+$12.3M |
| Candriam S.C.A. | $38.7M | 72,121 | 0.17% | 6q | -15.1%-$6.9M |
| GROUP ONE TRADING LLC | $37.1M CALL+PUT | options only | 0.05% | 25q | OPTIONS |
| JPMORGAN CHASE & CO | $37.1M incl. $21.1M options CALL | 29,473 | 0.00% | new | NEW |
| Tri Locum Partners LP | $36.7M | 68,273 | 4.51% | 15q | -33.9%-$18.8M |
| Vestal Point Capital, LP | $34.9M | 65,000 | 0.82% | 2q | +106.6%+$18.0M |
| Allspring Global Investments Holdings, LLC | $34.8M | 67,668 | 0.05% | 3q | +5548.4%+$34.2M |
| IMC-Chicago, LLC | $33.7M incl. $27.9M options CALL+PUT | 10,847 | 0.01% | 3q | +39.2%+$9.5M |
| VOYA INVESTMENT MANAGEMENT LLC | $32.9M | 61,202 | 0.03% | 31q | +2.1%+$661.0K |
| BNP PARIBAS FINANCIAL MARKETS | $31.1M | 57,998 | 0.01% | 31q | +1.4%+$440.8K |
| Jones Hill Capital LP | $28.2M | 52,545 | 6.00% | new | NEW |
| EULAV Asset Management | $27.9M | 52,000 | 0.89% | 11q | +6.1%+$1.6M |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $27.2M | 51,630 | 0.02% | 11q | +29.6%+$6.2M |
| Russell Investments Group, Ltd. | $26.5M | 49,294 | 0.02% | 10q | +10.8%+$2.6M |
| RENAISSANCE TECHNOLOGIES LLC | $24.7M | 45,942 | 0.03% | 8q | -36.1%-$13.9M |
| Affinity Asset Advisors, LLC | $21.5M | 40,000 | 0.97% | 19q | -27.3%-$8.1M |
| Mirae Asset Global Investments Co., Ltd. | $17.9M | 33,420 | 0.03% | 13q | -18.3%-$4.0M |
| Nuveen, LLC | $17.5M | 32,631 | 0.00% | 6q | -47.4%-$15.8M |
| SEGALL BRYANT & HAMILL, LLC | $17.4M | 32,444 | 0.21% | 4q | +1.8%+$308.2K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $17.4M | 32,403 | 0.00% | 14q | +36.2%+$4.6M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $17.2M | 31,998 | 0.02% | 5q | -2.7%-$473.1K |
| GROUPAMA ASSET MANAGMENT | $16.6M | 30,941 | 0.21% | 11q | -12.2%-$2.3M |
| Swiss National Bank | $16.1M | 29,940 | 0.01% | 31q | +2.5%+$386.6K |
| PFM Health Sciences, LP | $15.7M | 29,313 | 1.35% | 3q | -14.2%-$2.6M |
| CANADA PENSION PLAN INVESTMENT BOARD | $15.6M | 29,080 | 0.01% | 7q | +137.2%+$9.0M |
| Rockefeller Capital Management L.P. | $15.6M | 29,015 | 0.02% | 14q | -14.3%-$2.6M |
| GILDER GAGNON HOWE & CO LLC | $15.3M | 28,573 | 0.16% | 10q | -2.8%-$439.2K |
| SIMPLEX TRADING, LLC | $15.1M CALL+PUT | options only | 0.01% | 2q | OPTIONS |
| WELLS FARGO & COMPANY/MN | $14.2M | 26,536 | 0.00% | 31q | -17.6%-$3.0M |
| SEI INVESTMENTS CO | $13.9M | 25,826 | 0.01% | 15q | +6.7%+$874.1K |
| Integral Health Asset Management, LLC | $13.4M | 25,000 | 0.53% | 2q | HELD |
| California Public Employees Retirement System | $13.0M | 24,277 | 0.01% | 14q | +4.7%+$579.4K |
| WCM INVESTMENT MANAGEMENT, LLC | $12.1M | 22,985 | 0.02% | 4q | -2.4%-$303.2K |
| Susquehanna Portfolio Strategies, LLC | $11.8M | 22,003 | 0.19% | 5q | +252.0%+$8.5M |
| Tao Capital Management LP | $11.3M | 21,000 | 0.58% | 24q | HELD |
| HSBC HOLDINGS PLC | $10.9M | 20,240 | 0.00% | 3q | +1738.3%+$10.3M |
| FIRST TRUST ADVISORS LP | $10.6M | 19,826 | 0.01% | 8q | -10.8%-$1.3M |
| Weiss Asset Management LP | $10.4M | 19,325 | 0.11% | new | NEW |
| RAYMOND JAMES FINANCIAL INC | $10.4M | 19,305 | 0.00% | 7q | -71.0%-$25.4M |
| ArrowMark Colorado Holdings LLC | $10.0M | 18,624 | 0.42% | 10q | -70.2%-$23.5M |
| RHUMBLINE ADVISERS | $9.7M | 18,154 | 0.01% | 31q | -16.6%-$1.9M |
| SPHERA FUNDS MANAGEMENT LTD. | $9.4M | 17,419 | 1.22% | 3q | +92.7%+$4.5M |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $9.2M | 17,197 | 0.01% | 31q | +0.9%+$80.5K |
Showing the largest 100 of 422 reported holders.
What the company announced
Form 8-K filings from the last 120 days, showing only the items worth a reader's attention. Earnings releases, exhibit attachments and general disclosures are filed constantly and are left out. Filed is when the SEC received it; event is the date the company says the thing happened.
| Filed | Event date | What | Source |
|---|---|---|---|
| 2026-08-12 | 2026-08-11 | Directors or officers departed or appointed | filing |
What the insiders did
Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.
Officers and directors
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-09-09 | Sibold William John | President and CEO | Sold | 6,362 | $3.4M ×14 |
| 2026-05-22 | Levy Richard S | Director | Sold | 5,682 | $2.9M ×12 |
| 2026-09-11 | Sibold William John | President and CEO | Sold | 5,221 | $2.8M ×10 |
| 2026-07-20 | Sibold William John | President and CEO | Sold | 2,500 | $1.4M ×10 |
| 2026-06-01 | Soergel David | Chief Medical Officer | Sold | 1,042 | $516.6K |
| 2026-05-18 | Soergel David | Chief Medical Officer | Sold | 844 | $435.4K |
| 2026-08-17 | Kelley Shannon T | General Counsel | Sold | 664 | $341.9K |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 103 | $130.5M | 260,762 | 21 | 25 | 23 | 0.0% |
| Q2 2026 | 422 | $13.4B | 23,715,178 | 75 | 144 | 131 | 5.3% |
| Q1 2026 | 388 | $13.0B | 23,775,869 | 62 | 121 | 126 | 4.6% |
| Q4 2025 | 392 | $14.3B | 23,570,231 | 71 | 133 | 114 | 4.2% |
| Q3 2025 | 361 | $11.3B | 23,438,439 | 84 | 102 | 107 | 5.2% |
| Q2 2025 | 313 | $7.6B | 23,581,799 | 36 | 100 | 109 | 5.9% |
| Q1 2025 | 330 | $8.4B | 23,727,526 | 71 | 104 | 86 | 6.1% |
| Q4 2024 | 294 | $7.8B | 22,954,120 | 53 | 94 | 77 | 8.7% |
| Q3 2024 | 266 | $5.2B | 22,743,219 | 44 | 82 | 82 | 7.4% |
| Q2 2024 | 266 | $6.9B | 22,924,818 | 44 | 103 | 69 | 7.4% |
| Q1 2024 | 279 | $6.6B | 21,839,472 | 79 | 85 | 76 | 11.6% |
| Q4 2023 | 233 | $5.1B | 20,015,519 | 46 | 88 | 58 | 9.5% |
| Q3 2023 | 209 | $2.9B | 17,386,191 | 33 | 90 | 54 | 11.7% |
| Q2 2023 | 215 | $4.1B | 14,916,078 | 35 | 84 | 61 | 16.9% |
| Q1 2023 | 231 | $4.0B | 14,220,214 | 68 | 73 | 54 | 13.4% |
| Q4 2022 | 203 | $4.8B | 13,508,984 | 89 | 51 | 46 | 19.1% |
| Q3 2022 | 132 | $862.0M | 12,483,941 | 19 | 45 | 28 | 5.9% |
| Q2 2022 | 134 | $1.1B | 14,422,177 | 26 | 39 | 39 | 3.0% |
| Q1 2022 | 134 | $1.5B | 14,721,303 | 20 | 43 | 43 | 1.7% |
| Q4 2021 | 141 | $1.5B | 17,321,041 | 21 | 43 | 34 | 1.6% |
| Q3 2021 | 129 | $1.3B | 16,171,663 | 9 | 44 | 40 | 1.2% |
| Q2 2021 | 144 | $1.5B | 15,051,849 | 28 | 58 | 34 | 0.7% |
| Q1 2021 | 132 | $1.7B | 14,801,282 | 16 | 46 | 34 | 0.7% |
| Q4 2020 | 130 | $1.8B | 15,983,656 | 17 | 45 | 38 | 0.8% |
| Q3 2020 | 122 | $1.7B | 14,287,274 | 12 | 36 | 46 | 2.8% |
| Q2 2020 | 122 | $1.8B | 15,197,532 | 29 | 41 | 33 | 2.5% |
| Q1 2020 | 106 | $1.2B | 17,429,973 | 15 | 44 | 25 | 0.9% |
| Q4 2019 | 120 | $1.3B | 13,401,172 | 19 | 40 | 35 | 2.4% |
| Q3 2019 | 110 | $1.1B | 12,299,564 | 13 | 43 | 27 | 2.0% |
| Q2 2019 | 120 | $1.4B | 12,130,555 | 14 | 57 | 22 | 6.5% |
| Q1 2019 | 136 | $1.6B | 11,908,627 | 21 | 45 | 31 | 7.1% |
| Q4 2018 | 139 | $1.4B | 11,357,329 | 1 | 3 | 2 | 8.1% |