DaveManuel.com · Institutional Ownership · Who Owns It
PRIME MEDICINE INC (PRME)
Institutional ownership reported to the SEC as of Q2 2026, across 19 quarters.
190
Reporting holders
$399.2M
Reported value
58.8%
Of shares outstanding
0.7%
Calls
0.7%
Puts
-2
Holder change
Institutions report 106,659,529 shares against 181,376,856 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| Alphabet Inc. | $61.1M | 16,562,498 | 0.06% | 15q | HELD |
| BlackRock, Inc. | $35.4M | 9,602,041 | 0.00% | 8q | +12.9%+$4.1M |
| ARK Investment Management LLC | $30.8M | 8,348,746 | 0.20% | 15q | +33.6%+$7.8M |
| STATE STREET CORP | $28.0M | 7,576,460 | 0.00% | 15q | +19.4%+$4.5M |
| T. Rowe Price Investment Management, Inc. | $19.3M | 5,237,332 | 0.01% | 10q | -4.5%-$902.4K |
| VANGUARD CAPITAL MANAGEMENT LLC | $16.7M | 4,522,640 | 0.00% | 2q | +1.1%+$178.9K |
| Balyasny Asset Management L.P. | $14.6M | 3,969,082 | 0.02% | 4q | -3.7%-$569.3K |
| GOLDMAN SACHS GROUP INC | $12.7M | 3,430,518 | 0.00% | 12q | +253.5%+$9.1M |
| Casdin Capital, LLC | $11.7M | 3,167,175 | 0.58% | 15q | HELD |
| Woodline Partners LP | $11.1M | 3,003,904 | 0.03% | 4q | HELD |
| UBS Group AG | $10.3M | 2,794,689 | 0.00% | 15q | -3.2%-$345.9K |
| GEODE CAPITAL MANAGEMENT, LLC | $10.0M | 2,712,446 | 0.00% | 15q | -1.1%-$115.4K |
| Sumitomo Mitsui Trust Group, Inc. | $8.9M | 2,412,984 | 0.01% | 15q | -17.9%-$1.9M |
| Amova Asset Management Americas, Inc. | $8.9M | 2,407,018 | 0.11% | 15q | -18.2%-$2.0M |
| CITADEL ADVISORS LLC | $8.7M incl. $1.1M options CALL+PUT | 2,054,543 | 0.00% | 12q | +510.8%+$7.3M |
| ADAR1 Capital Management, LLC | $7.4M | 1,997,552 | 0.34% | 2q | +1.2%+$89.6K |
| FMR LLC | $6.5M | 1,761,884 | 0.00% | 15q | HELD |
| TWO SIGMA INVESTMENTS, LP | $5.6M | 1,524,511 | 0.00% | 12q | -3.1%-$178.2K |
| Redmile Group, LLC | $5.1M | 1,389,632 | 0.34% | 2q | -12.6%-$742.4K |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | $4.6M | 1,240,843 | 0.02% | 10q | HELD |
| Jump Financial, LLC | $4.6M | 1,240,429 | 0.04% | new | NEW |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $4.5M incl. $2.1M options CALL+PUT | 648,479 | 0.00% | 11q | -9.4%-$469.8K |
| BANK OF AMERICA CORP /DE/ | $3.6M | 981,335 | 0.00% | 15q | +70.1%+$1.5M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $3.5M | 961,826 | 0.00% | 2q | +11.6%+$367.6K |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $3.4M | 927,538 | 0.00% | 15q | +1.1%+$38.1K |
| NORTHERN TRUST CORP | $3.4M | 912,597 | 0.00% | 15q | +2.9%+$95.5K |
| JPMORGAN CHASE & CO | $3.0M | 810,095 | 0.00% | 15q | -4.0%-$126.7K |
| Greenwich Wealth Management LLC | $2.8M | 768,001 | 0.10% | 14q | +2.4%+$66.4K |
| VANGUARD FIDUCIARY TRUST CO | $2.8M | 764,633 | 0.00% | 2q | +6.6%+$175.8K |
| MORGAN STANLEY | $2.6M | 708,963 | 0.00% | 15q | +10.9%+$256.5K |
| Alessandra Capital Management, LLC | $2.5M | 666,603 | 1.74% | 2q | +56.7%+$889.6K |
| D. E. Shaw & Co., Inc. | $2.4M | 648,940 | 0.00% | 4q | -53.4%-$2.7M |
| Point72 Asset Management, L.P. | $2.0M | 533,553 | 0.00% | new | NEW |
| MOORE CAPITAL MANAGEMENT, LP | $1.8M | 500,000 | 0.03% | 10q | HELD |
| CHELSEA COUNSEL CO | $1.7M | 449,060 | 0.70% | 15q | -2.9%-$49.0K |
| MILLENNIUM MANAGEMENT LLC | $1.6M | 427,097 | 0.00% | new | NEW |
| HighTower Advisors, LLC | $1.3M | 340,365 | 0.00% | 13q | HELD |
| DIMENSIONAL FUND ADVISORS LP | $1.1M | 304,678 | 0.00% | 3q | HELD |
| WELLINGTON MANAGEMENT GROUP LLP | $1.1M | 304,444 | 0.00% | 4q | +9.5%+$97.1K |
| Nuveen, LLC | $1.0M | 275,931 | 0.00% | 6q | HELD |
| JANE STREET GROUP, LLC | $1.0M CALL+PUT | options only | 0.00% | 5q | OPTIONS |
| WELLS FARGO & COMPANY/MN | $928.9K | 251,747 | 0.00% | 14q | -21.2%-$250.2K |
| SIMPLEX TRADING, LLC | $925.1K CALL+PUT | options only | 0.00% | 11q | OPTIONS |
| Bank of New York Mellon Corp | $909.0K | 246,344 | 0.00% | 15q | -7.8%-$77.0K |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | $833.2K | 225,799 | 0.05% | 9q | +9.9%+$75.3K |
| MARSHALL WACE, LLP | $800.1K | 216,841 | 0.00% | 2q | +52.8%+$276.3K |
| XTX Topco Ltd | $796.0K | 215,708 | 0.01% | 5q | +37.1%+$215.6K |
| Jain Global LLC | $794.2K | 215,218 | 0.00% | new | NEW |
| JUPITER ASSET MANAGEMENT LTD | $773.0K | 209,490 | 0.00% | new | NEW |
| Swiss National Bank | $768.6K | 208,300 | 0.00% | 3q | +16.6%+$109.6K |
| PEAK6 LLC | $767.7K | 208,057 | 0.00% | new | NEW |
| CITIGROUP INC | $722.0K | 195,664 | 0.00% | 15q | +314.3%+$547.7K |
| Green Alpha Advisors, LLC | $682.7K | 185,023 | 0.46% | 7q | -3.2%-$22.7K |
| Keystone Financial Group | $614.4K | 166,510 | 0.04% | 4q | HELD |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $599.5K | 162,338 | 0.00% | 9q | +32.6%+$147.3K |
| PRICE T ROWE ASSOCIATES INC /MD/ | $599.0K | 162,325 | 0.00% | 15q | +21.4%+$105.4K |
| HRT FINANCIAL LP | $595.0K | 161,510 | 0.00% | 5q | -73.6%-$1.7M |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $579.5K | 157,049 | 0.00% | 4q | +81.6%+$260.4K |
| Bollard Group LLC | $558.0K | 151,136 | 0.02% | 11q | -58.1%-$775.3K |
| Rafferty Asset Management, LLC | $536.1K | 145,275 | 0.00% | 3q | -32.6%-$259.4K |
| GROUP ONE TRADING LLC | $527.7K CALL+PUT | options only | 0.00% | 11q | OPTIONS |
| ALLIANCEBERNSTEIN L.P. | $523.0K | 150,300 | 0.00% | 13q | +22.7%+$96.9K |
| Invesco Ltd. | $517.7K | 140,308 | 0.00% | 10q | +44.8%+$160.3K |
| Concurrent Investment Advisors, LLC | $486.1K | 131,722 | 0.00% | 2q | +77.6%+$212.3K |
| ExodusPoint Capital Management, LP | $437.1K | 118,464 | 0.00% | new | NEW |
| AQR CAPITAL MANAGEMENT LLC | $435.4K | 117,998 | 0.00% | 7q | -78.7%-$1.6M |
| Virtus Investment Advisers, LLC | $435.1K | 117,909 | 0.10% | 3q | +77.3%+$189.7K |
| RENAISSANCE TECHNOLOGIES LLC | $433.2K | 117,412 | 0.00% | 6q | -84.2%-$2.3M |
| RHUMBLINE ADVISERS | $430.8K | 116,754 | 0.00% | 13q | +2.2%+$9.2K |
| FIL Ltd | $425.1K | 115,206 | 0.00% | 15q | HELD |
| DEUTSCHE BANK AG\ | $422.4K | 114,472 | 0.00% | 15q | -27.3%-$158.6K |
| Steward Partners Investment Advisory, LLC | $399.6K | 108,290 | 0.00% | 4q | -7.8%-$33.8K |
| Palumbo Wealth Management LLC | $383.0K | 103,801 | 0.08% | 6q | +1.5%+$5.7K |
| MILESTONE ASSET MANAGEMENT, LLC | $369.1K | 100,035 | 0.06% | new | NEW |
| TD Asset Management Inc | $347.4K | 94,148 | 0.00% | 15q | HELD |
| LPL Financial LLC | $340.1K | 92,174 | 0.00% | 6q | +38.8%+$95.0K |
| Rockefeller Capital Management L.P. | $334.8K | 90,735 | 0.00% | 4q | -0.7%-$2.5K |
| BARCLAYS PLC | $324.9K | 88,058 | 0.00% | 15q | +38.1%+$89.6K |
| Squarepoint Ops LLC | $324.8K | 88,029 | 0.00% | 5q | -6.4%-$22.3K |
| COMMONWEALTH EQUITY SERVICES, LLC | $322.2K | 87,310 | 0.00% | 5q | +431.2%+$261.5K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $314.8K | 85,300 | 0.00% | 3q | HELD |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $303.7K | 82,305 | 0.00% | 2q | +56.4%+$109.6K |
| PROFUND ADVISORS LLC | $268.0K | 72,624 | 0.01% | 3q | -24.2%-$85.5K |
| Legal & General Group Plc | $245.2K | 66,444 | 0.00% | 15q | HELD |
| BNP PARIBAS FINANCIAL MARKETS | $243.9K | 66,101 | 0.00% | 7q | +92.1%+$116.9K |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $239.1K | 64,800 | 0.00% | 5q | -51.9%-$258.3K |
| Jupiter Topco LLC | $224.4K | 60,900 | 0.00% | new | FIRST |
| Engineers Gate Manager LP | $218.2K | 59,133 | 0.00% | 4q | -46.4%-$189.0K |
| VANGUARD ASSET MANAGEMENT, Ltd | $217.8K | 59,021 | 0.00% | 2q | HELD |
| SG Americas Securities, LLC | $217.0K | 58,922 | 0.00% | new | NEW |
| &PARTNERS | $210.6K | 57,460 | 0.00% | 4q | -3.4%-$7.4K |
| MetLife Investment Management, LLC | $207.3K | 56,192 | 0.00% | 5q | +27.1%+$44.2K |
| Russell Investments Group, Ltd. | $188.2K | 50,994 | 0.00% | 9q | -20.7%-$49.0K |
| AMERIPRISE FINANCIAL INC | $184.3K | 49,941 | 0.00% | 4q | +0.7%+$1.3K |
| Mutual Advisors, LLC | $166.1K | 45,000 | 0.00% | 5q | HELD |
| Vanguard Global Advisers, LLC | $163.4K | 44,269 | 0.00% | 2q | HELD |
| Quadrature Capital Ltd | $161.1K | 43,663 | 0.00% | 4q | -6.9%-$11.9K |
| IvyRock Asset Management (HK) Ltd | $154.2K | 41,800 | 0.09% | 4q | HELD |
| Corient Private Wealth LP | $144.2K | 39,078 | 0.00% | 4q | -5.2%-$7.9K |
| JONES FINANCIAL COMPANIES LLLP | $140.2K | 40,867 | 0.00% | 4q | +1.4%+$1.9K |
Showing the largest 100 of 190 reported holders.
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 30 | $11.2M | 3,650,509 | 3 | 12 | 7 | 0.0% |
| Q2 2026 | 190 | $399.2M | 106,659,529 | 22 | 58 | 65 | 1.4% |
| Q1 2026 | 192 | $349.0M | 98,524,561 | 31 | 67 | 47 | 1.9% |
| Q4 2025 | 187 | $348.0M | 98,118,355 | 43 | 62 | 43 | 2.2% |
| Q3 2025 | 168 | $528.2M | 92,450,302 | 54 | 62 | 31 | 3.1% |
| Q2 2025 | 122 | $147.7M | 58,691,462 | 28 | 35 | 32 | 1.8% |
| Q1 2025 | 126 | $120.8M | 60,402,278 | 22 | 38 | 33 | 0.3% |
| Q4 2024 | 132 | $188.8M | 64,335,842 | 30 | 38 | 31 | 0.4% |
| Q3 2024 | 115 | $268.5M | 68,748,420 | 14 | 38 | 29 | 0.9% |
| Q2 2024 | 120 | $355.2M | 68,926,658 | 25 | 41 | 29 | 0.3% |
| Q1 2024 | 114 | $470.5M | 67,098,124 | 22 | 39 | 31 | 0.2% |
| Q4 2023 | 106 | $434.7M | 48,948,552 | 29 | 24 | 25 | 0.2% |
| Q3 2023 | 82 | $472.4M | 49,517,421 | 11 | 34 | 13 | 0.0% |
| Q2 2023 | 77 | $675.7M | 46,131,758 | 17 | 36 | 12 | 0.0% |
| Q1 2023 | 73 | $616.9M | 50,260,504 | 15 | 30 | 6 | 0.0% |
| Q4 2022 | 66 | $767.8M | 41,322,585 | 65 | 0 | 0 | 0.0% |
| Q2 2019 | 4 | $1.1M | 53,032 | 1 | 2 | 0 | 0.0% |
| Q1 2019 | 4 | $882.0K | 42,217 | 1 | 0 | 1 | 0.0% |
| Q4 2018 | 5 | $494.0K | 27,533 | 0 | 0 | 0 | 0.0% |