DaveManuel.com · Institutional Ownership · Who Owns It
SYNDAX PHARMACEUTICALS INC (SNDX)
Institutional ownership reported to the SEC as of Q2 2026, across 32 quarters.
244
Reporting holders
$2.4B
Reported value
121.1%
Of shares outstanding
1.1%
Calls
0.1%
Puts
-4
Holder change
Institutions report 108,144,194 shares against 89,297,086 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| BlackRock, Inc. | $197.2M | 9,020,006 | 0.00% | 8q | +9.3%+$16.7M |
| Kynam Capital Management, LP | $176.0M | 8,050,959 | 9.73% | 19q | HELD |
| GOLDMAN SACHS GROUP INC | $128.1M | 5,861,265 | 0.01% | 31q | +17.3%+$18.9M |
| STATE STREET CORP | $123.7M | 5,658,424 | 0.00% | 31q | +27.7%+$26.9M |
| BANK OF AMERICA CORP /DE/ | $88.4M | 4,045,094 | 0.01% | 31q | -4.8%-$4.5M |
| VANGUARD CAPITAL MANAGEMENT LLC | $85.9M | 3,927,892 | 0.00% | 2q | +2.8%+$2.3M |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $82.6M | 3,779,900 | 0.86% | 2q | HELD |
| Eversept Partners, LP | $61.2M | 2,798,210 | 3.17% | 17q | -3.0%-$1.9M |
| GEODE CAPITAL MANAGEMENT, LLC | $56.5M | 2,584,136 | 0.00% | 31q | +19.8%+$9.3M |
| Hood River Capital Management LLC | $56.1M | 2,564,279 | 0.41% | 3q | +8.9%+$4.6M |
| KINGDON CAPITAL MANAGEMENT, L.L.C. | $54.6M | 2,500,000 | 5.60% | 11q | HELD |
| FRANKLIN RESOURCES INC | $50.0M | 2,286,499 | 0.01% | 11q | +6.3%+$3.0M |
| MILLENNIUM MANAGEMENT LLC | $44.9M | 2,053,960 | 0.02% | 14q | +929.4%+$40.5M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $42.0M | 1,921,796 | 0.00% | 2q | +10.6%+$4.0M |
| SILVERARC CAPITAL MANAGEMENT, LLC | $41.7M incl. $15.2M options CALL | 1,214,390 | 4.33% | 9q | +36.6%+$11.2M |
| UBS Group AG | $41.4M | 1,893,750 | 0.01% | 31q | +64.2%+$16.2M |
| Elmind Capital, LP | $40.6M | 1,855,000 | 10.19% | 3q | HELD |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $39.1M | 1,790,173 | 0.04% | 8q | +3.3%+$1.3M |
| Candriam S.C.A. | $37.0M | 1,696,040 | 0.17% | 14q | +83.3%+$16.8M |
| Soleus Capital Management, L.P. | $35.6M | 1,628,039 | 1.23% | 15q | -5.7%-$2.2M |
| TWO SIGMA INVESTMENTS, LP | $34.5M | 1,578,125 | 0.02% | 12q | HELD |
| ORBIMED ADVISORS LLC | $33.7M | 1,542,000 | 0.62% | 2q | +60.2%+$12.7M |
| Nuveen, LLC | $29.8M | 1,364,575 | 0.01% | 6q | -8.7%-$2.8M |
| MPM BIOIMPACT LLC | $29.2M | 1,333,523 | 1.78% | 4q | -0.5%-$157.6K |
| Aisling Capital Management LP | $28.8M | 1,316,806 | 6.10% | 26q | HELD |
| Woodline Partners LP | $27.3M | 1,250,760 | 0.08% | 13q | HELD |
| D. E. Shaw & Co., Inc. | $27.1M | 1,239,954 | 0.01% | 16q | -22.6%-$7.9M |
| Catalio Capital Management, LP | $26.6M | 1,215,698 | 4.99% | 6q | +16.5%+$3.8M |
| Prosight Management, LP | $26.2M | 1,200,000 | 4.52% | 9q | +55.8%+$9.4M |
| Trails Edge Capital Partners, LP | $24.3M | 1,110,000 | 3.85% | 2q | +58.2%+$8.9M |
| ALGERT GLOBAL LLC | $23.0M | 1,051,465 | 0.27% | 19q | +13.2%+$2.7M |
| Bank of New York Mellon Corp | $22.7M | 1,040,079 | 0.00% | 31q | +3.5%+$777.8K |
| SPHERA FUNDS MANAGEMENT LTD. | $22.2M | 1,014,606 | 2.89% | 26q | +40.0%+$6.3M |
| LOOMIS SAYLES & CO L P | $20.2M | 923,624 | 0.03% | new | NEW |
| Parkman Healthcare Partners LLC | $19.2M | 877,256 | 1.96% | 13q | -2.7%-$530.2K |
| Ensign Peak Advisors, Inc | $19.0M | 867,831 | 0.03% | 27q | -12.4%-$2.7M |
| Palo Alto Investors LP | $18.9M | 864,986 | 2.61% | 26q | HELD |
| AQR CAPITAL MANAGEMENT LLC | $18.7M | 853,304 | 0.01% | 18q | -13.0%-$2.8M |
| NORTHERN TRUST CORP | $18.5M | 845,537 | 0.00% | 31q | +11.9%+$2.0M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $17.8M | 814,303 | 0.00% | 31q | +13.9%+$2.2M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $16.6M incl. $6.7M options CALL+PUT | 454,101 | 0.00% | 31q | +131.0%+$9.4M |
| VANGUARD FIDUCIARY TRUST CO | $13.8M | 633,509 | 0.00% | 2q | +5.5%+$721.2K |
| MORGAN STANLEY | $12.9M | 588,979 | 0.00% | 35q | -34.1%-$6.7M |
| Rhenman & Partners Asset Management AB | $12.2M | 560,250 | 1.16% | 10q | +47.7%+$4.0M |
| Apis Capital Advisors, LLC | $12.2M | 556,000 | 1.18% | 4q | +1.1%+$131.2K |
| PANAGORA ASSET MANAGEMENT INC | $11.9M | 546,517 | 0.04% | 4q | +119.1%+$6.5M |
| Qube Research & Technologies Ltd | $10.4M | 477,182 | 0.01% | 14q | +1223.8%+$9.6M |
| FIRST TRUST ADVISORS LP | $10.0M | 456,700 | 0.01% | new | NEW |
| Granahan Investment Management, LLC | $9.8M | 446,988 | 0.35% | 11q | +45.9%+$3.1M |
| Knott David M Jr | $9.6M | 437,245 | 5.05% | 10q | +3.6%+$333.3K |
| Jump Financial, LLC | $8.8M | 402,846 | 0.07% | new | NEW |
| Aberdeen Group plc | $8.1M | 372,766 | 0.01% | 7q | +29.9%+$1.9M |
| Squarepoint Ops LLC | $8.1M | 370,317 | 0.01% | 5q | +104.0%+$4.1M |
| JUPITER ASSET MANAGEMENT LTD | $8.0M | 366,568 | 0.04% | new | NEW |
| HRT FINANCIAL LP | $7.9M | 363,147 | 0.01% | 2q | +308.5%+$6.0M |
| AMERIPRISE FINANCIAL INC | $7.6M | 346,852 | 0.00% | 13q | +22.0%+$1.4M |
| CITADEL ADVISORS LLC | $7.5M incl. $1.9M options CALL+PUT | 258,278 | 0.00% | 31q | -59.1%-$10.9M |
| Hennion & Walsh Asset Management, Inc. | $7.5M | 342,883 | 0.21% | 5q | +59.6%+$2.8M |
| Jones Hill Capital LP | $7.4M | 340,000 | 1.58% | new | NEW |
| DAFNA Capital Management LLC | $7.3M | 335,255 | 1.40% | 25q | +54.2%+$2.6M |
| ENVESTNET ASSET MANAGEMENT INC | $7.2M | 327,617 | 0.00% | 3q | +682.4%+$6.2M |
| RENAISSANCE TECHNOLOGIES LLC | $7.0M | 321,600 | 0.01% | 7q | -35.4%-$3.9M |
| CITIGROUP INC | $6.9M incl. $2.6M options CALL+PUT | 195,703 | 0.00% | 31q | +862.5%+$6.2M |
| Brevan Howard Capital Management LP | $6.8M | 309,065 | 0.05% | 8q | +50.9%+$2.3M |
| Alyeska Investment Group, L.P. | $6.7M | 308,507 | 0.02% | new | NEW |
| Verition Fund Management LLC | $6.7M | 304,939 | 0.03% | new | NEW |
| MACKENZIE FINANCIAL CORP | $6.1M | 280,079 | 0.01% | new | NEW |
| Trexquant Investment LP | $5.6M | 255,949 | 0.03% | 3q | +26.8%+$1.2M |
| SECTOR GAMMA AS | $5.3M | 241,739 | 1.15% | 4q | -15.5%-$967.7K |
| Schonfeld Strategic Advisors LLC | $5.2M | 236,717 | 0.02% | 15q | -9.2%-$522.7K |
| JPMORGAN CHASE & CO | $5.1M | 231,446 | 0.00% | 31q | -10.5%-$599.6K |
| Pinnacle Financial Partners, Inc. | $4.7M | 217,173 | 0.03% | 3q | +7.4%+$325.5K |
| Man Group plc | $4.7M | 213,703 | 0.01% | 7q | +17.4%+$692.7K |
| Y-Intercept (Hong Kong) Ltd | $4.6M | 212,713 | 0.09% | new | NEW |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | $4.5M | 207,250 | 0.01% | 3q | -37.5%-$2.7M |
| Pictet Asset Management Holding SA | $4.5M | 207,936 | 0.00% | 5q | +1582.9%+$4.3M |
| Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group | $4.4M | 200,000 | 1.15% | 6q | HELD |
| SEI INVESTMENTS CO | $4.2M | 193,134 | 0.00% | 13q | -11.2%-$534.8K |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $3.9M | 180,000 | 0.01% | 3q | HELD |
| Swiss National Bank | $3.7M | 168,100 | 0.00% | 23q | +4.2%+$146.5K |
| Atom Investors LP | $3.6M | 162,524 | 0.32% | 3q | +4.2%+$143.4K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $3.5M | 161,323 | 0.00% | 23q | +7.7%+$252.0K |
| SummitTX Capital, L.P. | $3.1M | 140,797 | 0.08% | 6q | +112.2%+$1.6M |
| Invesco Ltd. | $3.0M | 138,060 | 0.00% | 24q | -45.4%-$2.5M |
| Russell Investments Group, Ltd. | $3.0M | 135,012 | 0.00% | 13q | +33.0%+$732.8K |
| Torray Investment Partners LLC | $2.9M | 133,835 | 0.39% | 3q | +27.6%+$633.2K |
| RHUMBLINE ADVISERS | $2.9M | 132,358 | 0.00% | 31q | +15.3%+$384.6K |
| WELLS FARGO & COMPANY/MN | $2.8M | 130,054 | 0.00% | 31q | +61.8%+$1.1M |
| PRICE T ROWE ASSOCIATES INC /MD/ | $2.8M | 128,199 | 0.00% | 16q | +19.7%+$460.6K |
| Pale Fire Capital SE | $2.7M | 125,550 | 0.19% | 3q | -55.9%-$3.5M |
| CAPITAL FUND MANAGEMENT S.A. | $2.7M | 125,091 | 0.01% | 5q | -14.1%-$447.6K |
| WELLINGTON MANAGEMENT GROUP LLP | $2.7M | 124,241 | 0.00% | 31q | +0.5%+$14.3K |
| PFM Health Sciences, LP | $2.6M | 118,422 | 0.22% | 4q | -51.7%-$2.8M |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $2.5M | 115,208 | 0.00% | new | NEW |
| ALLIANCEBERNSTEIN L.P. | $2.5M | 106,040 | 0.00% | 31q | -63.3%-$4.3M |
| BARCLAYS PLC | $2.1M incl. $1.1M options CALL | 48,695 | 0.00% | 31q | -3.2%-$71.8K |
| Rafferty Asset Management, LLC | $2.1M | 97,787 | 0.00% | 24q | -21.6%-$588.8K |
| DEUTSCHE BANK AG\ | $2.1M | 95,315 | 0.00% | 34q | +27.1%+$444.5K |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $2.0M | 93,481 | 0.00% | 31q | -9.2%-$208.3K |
| HUSSMAN STRATEGIC ADVISORS, INC. | $1.8M | 84,000 | 0.42% | new | NEW |
Showing the largest 100 of 244 reported holders.
What the insiders did
Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.
Officers and directors
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-07-08 | Metzger Michael A | Chief Executive Officer | Sold | 32,375 | $784.8K |
| 2026-06-11 | Botwood Nicholas A.J. | Head of R&D, CMO | Sold | 34,280 | $617.0K |
| 2026-06-12 | Botwood Nicholas A.J. | Head of R&D, CMO | Sold | 31,235 | $566.6K |
| 2026-06-01 | Metzger Michael A | Chief Executive Officer | Sold | 6,847 | $130.0K |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 36 | $14.4M | 766,340 | 3 | 13 | 12 | 0.0% |
| Q2 2026 | 244 | $2.4B | 108,144,194 | 36 | 95 | 77 | 1.2% |
| Q1 2026 | 248 | $2.4B | 100,640,130 | 38 | 94 | 68 | 1.0% |
| Q4 2025 | 232 | $2.1B | 99,980,425 | 28 | 80 | 77 | 2.1% |
| Q3 2025 | 234 | $1.6B | 101,412,092 | 42 | 78 | 71 | 2.3% |
| Q2 2025 | 218 | $982.8M | 102,080,507 | 31 | 83 | 67 | 2.7% |
| Q1 2025 | 223 | $1.3B | 101,058,041 | 31 | 84 | 58 | 2.0% |
| Q4 2024 | 220 | $1.3B | 98,036,514 | 29 | 86 | 57 | 1.9% |
| Q3 2024 | 211 | $1.8B | 89,595,668 | 38 | 80 | 56 | 1.8% |
| Q2 2024 | 195 | $1.8B | 88,448,331 | 23 | 86 | 55 | 0.5% |
| Q1 2024 | 189 | $2.3B | 94,605,599 | 34 | 79 | 54 | 0.8% |
| Q4 2023 | 178 | $2.0B | 92,217,733 | 31 | 82 | 41 | 1.7% |
| Q3 2023 | 177 | $1.2B | 72,581,273 | 25 | 74 | 58 | 11.3% |
| Q2 2023 | 166 | $1.5B | 71,025,518 | 26 | 79 | 42 | 0.5% |
| Q1 2023 | 162 | $1.6B | 73,565,210 | 30 | 74 | 31 | 0.4% |
| Q4 2022 | 159 | $1.8B | 71,710,473 | 32 | 59 | 45 | 0.3% |
| Q3 2022 | 134 | $31.1B | 1,293,903,460 | 26 | 58 | 26 | 0.0% |
| Q2 2022 | 119 | $20.2B | 1,051,964,841 | 12 | 42 | 34 | 0.0% |
| Q1 2022 | 132 | $999.8M | 57,442,526 | 25 | 49 | 29 | 0.2% |
| Q4 2021 | 129 | $1.5B | 66,617,192 | 26 | 41 | 31 | 0.6% |
| Q3 2021 | 121 | $1.7B | 90,923,859 | 20 | 35 | 37 | 0.1% |
| Q2 2021 | 113 | $1.1B | 63,585,842 | 11 | 51 | 30 | 0.3% |
| Q1 2021 | 130 | $1.3B | 58,047,762 | 13 | 53 | 42 | 0.7% |
| Q4 2020 | 140 | $1.3B | 58,837,829 | 50 | 50 | 23 | 1.2% |
| Q3 2020 | 100 | $630.2M | 42,538,844 | 15 | 23 | 36 | 0.4% |
| Q2 2020 | 97 | $656.9M | 43,222,306 | 29 | 47 | 11 | 2.4% |
| Q1 2020 | 85 | $446.8M | 40,138,284 | 21 | 25 | 26 | 1.4% |
| Q4 2019 | 72 | $156.0M | 17,222,046 | 12 | 19 | 19 | 3.1% |
| Q3 2019 | 74 | $136.3M | 17,389,304 | 11 | 24 | 15 | 4.7% |
| Q2 2019 | 73 | $169.7M | 17,782,435 | 12 | 33 | 12 | 2.4% |
| Q1 2019 | 69 | $90.8M | 17,215,156 | 8 | 19 | 24 | 0.4% |
| Q4 2018 | 74 | $73.1M | 15,900,678 | 2 | 0 | 3 | 3.2% |