DaveManuel.com · Institutional Ownership · Who Owns It
STOKE THERAPEUTICS INC (STOK)
Institutional ownership reported to the SEC as of Q2 2026, across 30 quarters.
198
Reporting holders
$2.5B
Reported value
119.9%
Of shares outstanding
0.0%
Calls
0.0%
Puts
+0
Holder change
Institutions report 77,376,438 shares against 64,526,242 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| BlackRock, Inc. | $192.3M | 5,877,357 | 0.00% | 8q | +9.1%+$16.1M |
| RTW INVESTMENTS, LP | $184.0M | 5,623,525 | 1.57% | 29q | HELD |
| FMR LLC | $173.8M | 5,313,100 | 0.01% | 29q | -1.3%-$2.3M |
| Lynx1 Capital Management LP | $132.1M | 4,038,404 | 15.27% | 12q | -15.2%-$23.7M |
| Redmile Group, LLC | $129.1M | 3,945,920 | 8.67% | 29q | -5.2%-$7.1M |
| WELLINGTON MANAGEMENT GROUP LLP | $115.2M | 3,519,301 | 0.02% | 10q | +13.7%+$13.9M |
| MORGAN STANLEY | $113.0M | 3,452,795 | 0.01% | 29q | +0.9%+$965.7K |
| BAKER BROS. ADVISORS LP | $109.2M | 3,336,697 | 0.55% | 16q | HELD |
| TORONTO DOMINION BANK | $103.8M | 3,173,258 | 0.12% | 7q | HELD |
| STATE STREET CORP | $93.3M | 2,852,240 | 0.00% | 28q | +25.3%+$18.8M |
| PRICE T ROWE ASSOCIATES INC /MD/ | $87.1M | 2,661,739 | 0.01% | 29q | +37.6%+$23.8M |
| VANGUARD CAPITAL MANAGEMENT LLC | $84.6M | 2,586,937 | 0.00% | 2q | +9.8%+$7.6M |
| BVF INC/IL | $83.4M | 2,547,557 | 2.13% | 4q | HELD |
| T. Rowe Price Investment Management, Inc. | $79.0M | 2,415,139 | 0.05% | 2q | +862.5%+$70.8M |
| Assenagon Asset Management S.A. | $73.8M | 2,256,776 | 0.05% | 9q | +148.8%+$44.2M |
| Siren, L.L.C. | $65.3M | 1,995,347 | 1.32% | 7q | HELD |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $59.7M | 1,823,500 | 0.62% | 3q | HELD |
| Jupiter Topco LLC | $59.4M | 1,814,408 | 0.02% | new | FIRST |
| GEODE CAPITAL MANAGEMENT, LLC | $49.9M | 1,524,309 | 0.00% | 28q | +15.3%+$6.6M |
| DIMENSIONAL FUND ADVISORS LP | $33.2M | 1,013,911 | 0.01% | 24q | +2.4%+$784.4K |
| Polar Capital Holdings Plc | $27.3M | 833,716 | 0.06% | 5q | -26.4%-$9.8M |
| EcoR1 Capital, LLC | $24.0M | 735,000 | 1.17% | 2q | +635.0%+$20.8M |
| MPM BIOIMPACT LLC | $23.7M | 723,314 | 1.44% | 8q | -5.7%-$1.4M |
| Opaleye Management Inc. | $22.9M | 700,000 | 2.07% | 7q | HELD |
| GOLDMAN SACHS GROUP INC | $18.8M | 575,344 | 0.00% | 29q | -30.7%-$8.4M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $18.6M | 566,993 | 0.00% | 2q | +22.5%+$3.4M |
| BAILLIE GIFFORD & CO | $16.9M | 517,275 | 0.02% | 3q | -10.1%-$1.9M |
| NORTHERN TRUST CORP | $16.4M | 500,124 | 0.00% | 28q | +15.9%+$2.2M |
| CITADEL ADVISORS LLC | $16.3M incl. $327.2K options PUT | 489,301 | 0.00% | 24q | +297.7%+$12.2M |
| Troluce Capital Advisors LLC | $16.2M | 496,416 | 1.67% | 2q | -24.0%-$5.1M |
| FIRST TRUST ADVISORS LP | $16.1M | 490,913 | 0.01% | 4q | +200.3%+$10.7M |
| Candriam S.C.A. | $15.7M | 480,136 | 0.07% | 3q | -4.4%-$715.4K |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $15.3M | 467,012 | 0.00% | 28q | +6.8%+$976.3K |
| Granahan Investment Management, LLC | $15.1M | 461,608 | 0.54% | 17q | +37.6%+$4.1M |
| Erste Asset Management GmbH | $13.9M | 428,381 | 0.11% | 6q | -4.0%-$570.7K |
| VANGUARD FIDUCIARY TRUST CO | $13.2M | 402,503 | 0.00% | 2q | +12.8%+$1.5M |
| Parkman Healthcare Partners LLC | $11.6M | 355,443 | 1.19% | 4q | +5.6%+$619.2K |
| Artisan Partners Limited Partnership | $11.6M | 355,153 | 0.02% | 2q | +12.6%+$1.3M |
| JANE STREET GROUP, LLC | $10.9M | 331,701 | 0.00% | 11q | +415.5%+$8.7M |
| TANG CAPITAL MANAGEMENT LLC | $9.8M | 300,000 | 0.45% | 7q | -40.0%-$6.5M |
| MILLENNIUM MANAGEMENT LLC | $8.5M | 261,028 | 0.00% | 2q | -44.7%-$6.9M |
| BANK OF AMERICA CORP /DE/ | $8.5M | 259,708 | 0.00% | 28q | -52.2%-$9.3M |
| JPMORGAN CHASE & CO | $8.5M | 259,352 | 0.00% | 28q | -2.3%-$200.2K |
| UBS Group AG | $6.8M | 207,112 | 0.00% | 16q | +30.8%+$1.6M |
| Birchview Capital, LP | $5.8M | 178,110 | 2.73% | 26q | -15.2%-$1.0M |
| Bank of New York Mellon Corp | $5.4M | 164,273 | 0.00% | 28q | +14.6%+$682.7K |
| NORGES BANK | $5.3M | 163,200 | 0.00% | new | NEW |
| FRANKLIN RESOURCES INC | $4.8M | 146,395 | 0.00% | 10q | +2.5%+$117.9K |
| DAFNA Capital Management LLC | $4.3M | 130,875 | 0.82% | 10q | HELD |
| ExodusPoint Capital Management, LP | $4.2M | 129,660 | 0.03% | new | NEW |
| Nuveen, LLC | $4.0M | 122,877 | 0.00% | 6q | +13.1%+$466.6K |
| GILDER GAGNON HOWE & CO LLC | $3.7M | 113,065 | 0.04% | 29q | HELD |
| Jump Financial, LLC | $3.4M | 104,350 | 0.03% | new | NEW |
| Schonfeld Strategic Advisors LLC | $3.3M | 102,229 | 0.01% | 7q | +107.4%+$1.7M |
| Palo Alto Investors LP | $2.8M | 84,631 | 0.38% | 10q | HELD |
| BOOTHBAY FUND MANAGEMENT, LLC | $2.6M | 80,968 | 0.03% | 3q | +71.2%+$1.1M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $2.6M | 80,522 | 0.00% | 9q | +137.7%+$1.5M |
| XTX Topco Ltd | $2.6M | 79,613 | 0.03% | 2q | +888.5%+$2.3M |
| RHUMBLINE ADVISERS | $2.5M | 75,931 | 0.00% | 27q | +12.8%+$281.9K |
| Swiss National Bank | $2.4M | 74,200 | 0.00% | 9q | -6.2%-$160.3K |
| Trexquant Investment LP | $2.4M | 73,475 | 0.01% | new | NEW |
| PRINCIPAL FINANCIAL GROUP INC | $2.3M | 69,880 | 0.00% | 4q | +9.3%+$194.6K |
| CITIGROUP INC | $2.3M | 69,326 | 0.00% | 28q | +444.8%+$1.9M |
| Invesco Ltd. | $2.2M | 67,660 | 0.00% | 7q | -54.9%-$2.7M |
| TD Asset Management Inc | $2.2M | 67,200 | 0.00% | 2q | -9.7%-$235.6K |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $2.2M | 66,160 | 0.00% | 24q | -4.4%-$100.2K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $2.1M | 65,228 | 0.00% | 9q | +12.1%+$230.4K |
| Rhenman & Partners Asset Management AB | $2.1M | 64,500 | 0.20% | 4q | -22.3%-$605.3K |
| ALPS ADVISORS INC | $2.1M | 63,010 | 0.01% | 7q | +35.5%+$540.3K |
| TWO SIGMA INVESTMENTS, LP | $2.0M | 62,371 | 0.00% | new | NEW |
| ALLIANCEBERNSTEIN L.P. | $2.0M | 62,390 | 0.00% | 26q | +49.2%+$669.4K |
| HighVista Strategies LLC | $2.0M | 61,316 | 0.46% | 3q | -2.1%-$42.6K |
| STATE OF WISCONSIN INVESTMENT BOARD | $2.0M | 60,167 | 0.00% | 3q | +25.7%+$402.7K |
| PANAGORA ASSET MANAGEMENT INC | $1.9M | 58,843 | 0.01% | new | NEW |
| D. E. Shaw & Co., Inc. | $1.9M | 57,847 | 0.00% | 5q | +15.8%+$257.7K |
| DEUTSCHE BANK AG\ | $1.9M | 57,784 | 0.00% | 28q | +42.3%+$562.4K |
| WELLS FARGO & COMPANY/MN | $1.7M | 50,835 | 0.00% | 28q | +155.9%+$1.0M |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $1.6M | 50,138 | 0.00% | 28q | -2.8%-$48.0K |
| Woodline Partners LP | $1.6M | 50,120 | 0.01% | 14q | HELD |
| Quantinno Capital Management LP | $1.6M | 49,928 | 0.00% | 3q | +410.9%+$1.3M |
| NEW YORK STATE COMMON RETIREMENT FUND | $1.6M | 49,611 | 0.00% | 28q | +26.7%+$342.0K |
| Moran Wealth Management, LLC | $1.6M | 47,977 | 0.04% | 2q | +18.3%+$242.9K |
| VICTORY CAPITAL MANAGEMENT INC | $1.5M | 44,900 | 0.00% | 3q | +32.5%+$360.2K |
| Creative Planning | $1.5M | 44,368 | 0.00% | 6q | -7.8%-$122.4K |
| Rafferty Asset Management, LLC | $1.4M | 43,742 | 0.00% | 9q | -27.0%-$528.6K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1.4M CALL+PUT | options only | 0.00% | 14q | OPTIONS |
| HUSSMAN STRATEGIC ADVISORS, INC. | $1.4M | 42,000 | 0.32% | 3q | -50.0%-$1.4M |
| Quadrature Capital Ltd | $1.3M | 41,225 | 0.01% | 2q | +300.5%+$1.0M |
| PLATINUM INVESTMENT MANAGEMENT LTD | $1.3M | 40,815 | 0.33% | 4q | HELD |
| Legal & General Group Plc | $1.2M | 35,705 | 0.00% | 28q | +11.4%+$119.7K |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $1.2M | 35,598 | 0.00% | 5q | +16.8%+$167.5K |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $1.1M | 34,102 | 0.00% | 2q | HELD |
| Generali Investments, Management Co LLC | $1.1M | 33,149 | 0.24% | 4q | +379.6%+$858.5K |
| MetLife Investment Management, LLC | $1.1M | 32,132 | 0.00% | 27q | +23.1%+$197.2K |
| Corient Private Wealth LP | $1.0M | 30,823 | 0.00% | new | NEW |
| OMERS ADMINISTRATION Corp | $981.6K | 30,000 | 0.01% | 2q | -27.7%-$376.3K |
| Squarepoint Ops LLC | $959.0K | 29,310 | 0.00% | new | NEW |
| BNP PARIBAS FINANCIAL MARKETS | $883.8K | 27,012 | 0.00% | 28q | -51.9%-$952.7K |
| Vanguard Global Advisers, LLC | $871.6K | 26,639 | 0.00% | 2q | HELD |
| AQR CAPITAL MANAGEMENT LLC | $865.4K | 26,449 | 0.00% | 8q | -43.1%-$654.7K |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-09-30 | 13G | BVF PARTNERS L P/ILwith 9 co-filers | 5.6% |
What the company announced
Form 8-K filings from the last 120 days, showing only the items worth a reader's attention. Earnings releases, exhibit attachments and general disclosures are filed constantly and are left out. Filed is when the SEC received it; event is the date the company says the thing happened.
| Filed | Event date | What | Source |
|---|---|---|---|
| 2026-09-25 | 2026-09-22 | Directors or officers departed or appointed | filing |
What the insiders did
Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.
Officers and directors
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-08-18 | Kaye Edward M. MD | Director | Sold | 12,567 | $402.5K ×2 |
| 2026-07-01 | Ticho Barry | CHIEF MEDICAL OFFICER | Sold | 7,228 | $236.1K ×2 |
| 2026-08-03 | Ticho Barry | CHIEF MEDICAL OFFICER | Sold | 7,176 | $208.4K ×2 |
| 2026-09-01 | Ticho Barry | CHIEF MEDICAL OFFICER | Sold | 5,545 | $170.1K ×2 |
| 2026-08-18 | Ticho Barry | CHIEF MEDICAL OFFICER | Sold | 4,767 | $152.7K ×2 |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 32 | $36.9M | 1,418,585 | 3 | 9 | 10 | 0.0% |
| Q2 2026 | 198 | $2.5B | 77,376,438 | 28 | 74 | 56 | 0.1% |
| Q1 2026 | 198 | $2.3B | 71,116,887 | 34 | 76 | 51 | 0.5% |
| Q4 2025 | 185 | $2.1B | 66,984,195 | 41 | 52 | 55 | 1.1% |
| Q3 2025 | 156 | $1.6B | 67,715,814 | 39 | 45 | 40 | 1.0% |
| Q2 2025 | 134 | $746.3M | 65,692,235 | 26 | 48 | 31 | 0.1% |
| Q1 2025 | 125 | $422.6M | 63,384,293 | 26 | 42 | 28 | 0.2% |
| Q4 2024 | 129 | $643.0M | 58,272,255 | 22 | 37 | 40 | 0.0% |
| Q3 2024 | 117 | $721.0M | 58,616,570 | 22 | 37 | 33 | 0.1% |
| Q2 2024 | 117 | $846.1M | 62,602,299 | 32 | 46 | 22 | 0.0% |
| Q1 2024 | 107 | $847.5M | 62,510,640 | 38 | 34 | 27 | 0.5% |
| Q4 2023 | 82 | $255.8M | 48,631,140 | 5 | 28 | 27 | 0.0% |
| Q3 2023 | 98 | $173.8M | 44,028,299 | 17 | 27 | 36 | 0.2% |
| Q2 2023 | 101 | $498.0M | 46,545,835 | 14 | 39 | 28 | 0.6% |
| Q1 2023 | 98 | $388.3M | 46,604,367 | 8 | 34 | 39 | 0.0% |
| Q4 2022 | 106 | $372.1M | 40,284,928 | 13 | 38 | 37 | 0.1% |
| Q3 2022 | 101 | $563.6M | 43,313,709 | 19 | 31 | 28 | 1.0% |
| Q2 2022 | 89 | $583.9M | 44,131,310 | 10 | 38 | 19 | 0.1% |
| Q1 2022 | 97 | $897.7M | 42,485,077 | 20 | 31 | 26 | 0.4% |
| Q4 2021 | 91 | $1.2B | 50,279,315 | 15 | 32 | 22 | 0.0% |
| Q3 2021 | 88 | $872.3M | 34,222,916 | 8 | 25 | 30 | 0.1% |
| Q2 2021 | 96 | $1.2B | 35,771,655 | 10 | 40 | 25 | 0.2% |
| Q1 2021 | 105 | $2.0B | 51,537,549 | 24 | 31 | 25 | 0.4% |
| Q4 2020 | 96 | $2.6B | 42,578,220 | 18 | 33 | 22 | 0.2% |
| Q3 2020 | 89 | $1.3B | 38,554,983 | 23 | 15 | 28 | 0.1% |
| Q2 2020 | 70 | $958.0M | 40,522,150 | 13 | 17 | 23 | 0.1% |
| Q1 2020 | 66 | $1.1B | 48,255,072 | 12 | 27 | 16 | 0.0% |
| Q4 2019 | 62 | $1.1B | 37,170,663 | 13 | 23 | 13 | 0.0% |
| Q3 2019 | 51 | $3.1B | 145,806,714 | 23 | 13 | 8 | 0.0% |
| Q2 2019 | 47 | $2.9B | 99,172,585 | 47 | 0 | 0 | 0.0% |