DaveManuel.com · Institutional Ownership · Who Owns It
TANGO THERAPEUTICS INC (TNGX)
Institutional ownership reported to the SEC as of Q2 2026, across 21 quarters.
248
Reporting holders
$6.6B
Reported value
127.3%
Of shares outstanding
0.2%
Calls
0.1%
Puts
+53
Holder change
Institutions report 214,690,053 shares against 168,610,367 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| RTW INVESTMENTS, LP | $434.5M | 13,900,620 | 3.71% | 3q | +4.5%+$18.8M |
| BlackRock, Inc. | $388.8M | 12,438,444 | 0.01% | 8q | +42.2%+$115.4M |
| FMR LLC | $385.5M | 12,333,339 | 0.02% | 20q | +24.5%+$75.9M |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | $383.8M | 12,277,000 | 1.77% | 7q | +35.0%+$99.4M |
| Boxer Capital Management, LLC | $340.0M | 10,876,219 | 25.61% | 7q | HELD |
| GOLDMAN SACHS GROUP INC | $312.0M | 9,980,620 | 0.03% | 19q | +96.6%+$153.3M |
| TCG Crossover Management, LLC | $283.9M | 9,081,201 | 6.82% | 7q | -13.8%-$45.3M |
| Paradigm Biocapital Advisors LP | $198.7M | 6,357,523 | 3.72% | 2q | +58.6%+$73.4M |
| PRICE T ROWE ASSOCIATES INC /MD/ | $198.5M | 6,348,827 | 0.02% | 12q | +613.8%+$170.7M |
| Siren, L.L.C. | $193.2M | 6,179,364 | 3.91% | 8q | +9.2%+$16.3M |
| STATE STREET CORP | $186.9M | 5,979,806 | 0.01% | 20q | +28.5%+$41.5M |
| VANGUARD CAPITAL MANAGEMENT LLC | $186.2M | 5,957,348 | 0.00% | 2q | +15.4%+$24.9M |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $175.1M | 5,600,000 | 0.25% | 5q | -56.3%-$225.4M |
| Jupiter Topco LLC | $158.0M | 5,056,352 | 0.06% | new | FIRST |
| Deep Track Capital, LP | $131.3M | 4,200,000 | 1.91% | 4q | +52.7%+$45.3M |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $131.0M | 4,190,611 | 1.37% | 3q | +1.1%+$1.4M |
| Woodline Partners LP | $125.1M | 4,000,567 | 0.39% | 7q | -50.0%-$125.0M |
| TRV GP IV, LLC | $120.2M | 6,374,574 | 47.37% | 20q | HELD |
| GEODE CAPITAL MANAGEMENT, LLC | $117.0M | 3,742,791 | 0.01% | 20q | +39.9%+$33.4M |
| PERCEPTIVE ADVISORS LLC | $105.6M | 3,377,000 | 1.58% | 3q | +317.9%+$80.3M |
| Seven Fleet Capital Management LP | $95.7M | 3,228,144 | 15.79% | 3q | +543.0%+$80.8M |
| Logos Global Management LP | $89.1M | 2,850,000 | 3.84% | 4q | -5.0%-$4.7M |
| Caligan Partners LP | $78.2M | 2,500,103 | 3.68% | 3q | +3.8%+$2.9M |
| Holocene Advisors, LP | $75.4M | 2,410,939 | 0.17% | 2q | -38.7%-$47.6M |
| Commodore Capital LP | $70.3M | 2,250,000 | 4.19% | new | NEW |
| Balyasny Asset Management L.P. | $66.2M incl. $3.1M options CALL | 2,016,379 | 0.08% | 9q | -47.3%-$59.4M |
| Jefferies Financial Group Inc. | $62.8M | 2,010,534 | 0.41% | new | NEW |
| FRANKLIN RESOURCES INC | $59.0M | 1,887,211 | 0.01% | 11q | +45.6%+$18.5M |
| Candriam S.C.A. | $50.9M | 1,630,553 | 0.23% | 5q | +28.5%+$11.3M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $49.6M | 1,585,111 | 0.00% | 2q | +75.8%+$21.4M |
| JPMORGAN CHASE & CO | $46.3M | 1,418,193 | 0.00% | 20q | +2006.5%+$44.1M |
| Polar Capital Holdings Plc | $46.3M | 1,480,740 | 0.11% | new | NEW |
| Vivo Capital, LLC | $43.1M | 1,379,769 | 3.94% | 5q | -36.0%-$24.2M |
| DV EQUITIES, LLC | $41.2M | 1,318,551 | 5.91% | new | NEW |
| Cormorant Asset Management, LP | $40.6M | 1,300,000 | 2.08% | 2q | -8.8%-$3.9M |
| NORTHERN TRUST CORP | $38.5M | 1,231,933 | 0.00% | 20q | +42.8%+$11.5M |
| STEMPOINT CAPITAL LP | $38.4M incl. $175.0K options CALL | 1,223,019 | 6.62% | 2q | +204.4%+$25.8M |
| FEDERATED HERMES, INC. | $38.0M | 1,214,613 | 0.05% | 6q | +343011.0%+$38.0M |
| VOYA INVESTMENT MANAGEMENT LLC | $34.5M | 1,103,030 | 0.03% | 17q | +528.6%+$29.0M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $33.5M | 1,072,059 | 0.00% | 20q | +27.8%+$7.3M |
| AMERICAN CENTURY COMPANIES INC | $31.7M | 1,013,794 | 0.01% | new | NEW |
| Nantahala Capital Management, LLC | $31.3M | 1,001,318 | 0.52% | 7q | -19.9%-$7.8M |
| Integral Health Asset Management, LLC | $31.3M | 1,000,000 | 1.23% | 3q | +122.2%+$17.2M |
| VANGUARD FIDUCIARY TRUST CO | $28.6M | 915,565 | 0.01% | 2q | +38.1%+$7.9M |
| Nuveen, LLC | $27.8M | 890,170 | 0.01% | 6q | +146.7%+$16.5M |
| SAMLYN CAPITAL, LLC | $24.0M | 766,473 | 0.39% | new | NEW |
| RENAISSANCE TECHNOLOGIES LLC | $23.4M | 748,300 | 0.03% | new | NEW |
| Soleus Capital Management, L.P. | $22.2M | 709,000 | 0.76% | 5q | +57.6%+$8.1M |
| ArrowMark Colorado Holdings LLC | $22.1M | 708,385 | 0.92% | 11q | HELD |
| Bellevue Group AG | $21.7M | 694,182 | 0.46% | 3q | -71.1%-$53.3M |
| Alyeska Investment Group, L.P. | $21.6M | 691,109 | 0.06% | 2q | +3918.5%+$21.1M |
| Assenagon Asset Management S.A. | $21.6M | 690,312 | 0.01% | new | NEW |
| Connor, Clark & Lunn Investment Management Ltd. | $19.9M | 636,070 | 0.04% | 3q | +79.1%+$8.8M |
| BANK OF AMERICA CORP /DE/ | $18.8M | 600,834 | 0.00% | 19q | +83.7%+$8.6M |
| JANE STREET GROUP, LLC | $18.5M incl. $2.5M options CALL+PUT | 514,265 | 0.00% | 3q | HELD |
| Pictet Asset Management Holding SA | $18.3M | 582,262 | 0.02% | new | NEW |
| Fisher Asset Management, LLC | $18.1M | 578,158 | 0.01% | 11q | +256.0%+$13.0M |
| LORD, ABBETT & CO. LLC | $16.6M | 532,109 | 0.05% | new | NEW |
| MORGAN STANLEY | $16.0M | 510,778 | 0.00% | 20q | -65.4%-$30.2M |
| FIRST TRUST ADVISORS LP | $15.9M | 509,309 | 0.01% | new | NEW |
| BOOTHBAY FUND MANAGEMENT, LLC | $15.6M | 500,497 | 0.21% | 3q | -12.4%-$2.2M |
| MILLENNIUM MANAGEMENT LLC | $15.5M | 496,036 | 0.01% | 7q | +16.5%+$2.2M |
| DIMENSIONAL FUND ADVISORS LP | $15.3M | 488,300 | 0.00% | 12q | HELD |
| Invesco Ltd. | $14.5M | 462,721 | 0.00% | 17q | -20.3%-$3.7M |
| Rock Springs Capital Management LP | $14.3M | 456,551 | 0.70% | 3q | +18.0%+$2.2M |
| BOONE CAPITAL MANAGEMENT LLC | $14.2M | 455,605 | 3.33% | new | NEW |
| Longaeva Partners L.P. | $13.0M | 414,902 | 0.28% | new | NEW |
| EVENTIDE ASSET MANAGEMENT, LLC | $12.5M | 400,000 | 0.17% | new | NEW |
| ACUTA CAPITAL PARTNERS, LLC | $12.2M | 390,949 | 8.52% | 3q | -11.5%-$1.6M |
| Bank of New York Mellon Corp | $12.2M | 390,920 | 0.00% | 20q | +22.8%+$2.3M |
| UBS Group AG | $12.0M | 383,694 | 0.00% | 10q | -45.1%-$9.9M |
| CONGRESS ASSET MANAGEMENT CO | $11.9M | 380,746 | 0.07% | 9q | +11.5%+$1.2M |
| Mass General Brigham, Inc | $11.1M | 354,192 | 3.07% | 6q | HELD |
| BESSEMER GROUP INC | $11.1M | 354,206 | 0.02% | 17q | -50.0%-$11.1M |
| LMR Partners LLP | $10.9M | 347,106 | 0.04% | new | NEW |
| CITADEL ADVISORS LLC | $10.6M incl. $4.9M options CALL+PUT | 181,059 | 0.00% | 3q | +0.9%+$95.8K |
| BAKER BROS. ADVISORS LP | $10.4M | 333,333 | 0.05% | new | NEW |
| PFM Health Sciences, LP | $10.2M | 326,047 | 0.87% | 2q | -19.7%-$2.5M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $10.1M incl. $6.8M options CALL+PUT | 105,985 | 0.00% | 14q | +22.7%+$1.9M |
| AMERIPRISE FINANCIAL INC | $9.6M | 306,345 | 0.00% | 2q | -39.5%-$6.2M |
| Point72 Asset Management, L.P. | $9.3M | 298,339 | 0.01% | 4q | -44.1%-$7.4M |
| WELLINGTON MANAGEMENT GROUP LLP | $9.3M | 297,106 | 0.00% | 4q | +2.7%+$247.8K |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $9.1M | 278,511 | 0.01% | 2q | +34.2%+$2.3M |
| Handelsbanken Fonder AB | $9.0M | 287,900 | 0.03% | new | NEW |
| Russell Investments Group, Ltd. | $8.8M | 281,633 | 0.01% | 13q | +2093.4%+$8.4M |
| ALGERT GLOBAL LLC | $8.5M | 271,570 | 0.10% | 2q | +86.5%+$3.9M |
| HighVista Strategies LLC | $8.1M | 260,070 | 1.85% | 2q | +149.6%+$4.9M |
| SPHERA FUNDS MANAGEMENT LTD. | $7.9M | 254,250 | 1.04% | 3q | -26.0%-$2.8M |
| T. Rowe Price Investment Management, Inc. | $7.9M | 252,109 | 0.01% | 11q | -42.7%-$5.9M |
| TWO SIGMA INVESTMENTS, LP | $7.6M | 241,783 | 0.01% | 14q | +39.7%+$2.1M |
| KVP Capital Advisors, LP | $7.2M | 230,264 | 5.28% | 2q | HELD |
| TD Asset Management Inc | $6.9M | 221,968 | 0.01% | 2q | +116.3%+$3.7M |
| Sio Capital Management, LLC | $6.5M | 208,500 | 1.08% | new | NEW |
| Atle Fund Management AB | $6.2M | 198,557 | 1.67% | 2q | +563.7%+$5.3M |
| TRV GP VI, LLC | $6.1M | 194,174 | 2.61% | 7q | HELD |
| Walleye Capital LLC | $6.0M | 192,270 | 0.02% | new | NEW |
| Swiss National Bank | $5.9M | 187,400 | 0.00% | 3q | +113.4%+$3.1M |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $5.7M | 181,212 | 0.00% | 12q | +67.5%+$2.3M |
| VICTORY CAPITAL MANAGEMENT INC | $5.5M | 176,748 | 0.00% | 3q | +234.7%+$3.9M |
| RHUMBLINE ADVISERS | $5.5M | 175,133 | 0.00% | 17q | +38.3%+$1.5M |
Showing the largest 100 of 249 reported holders. The count of 248 above leaves out 1 position whose reported value failed our price check; it is listed here as filed.
What the company announced
Form 8-K filings from the last 120 days, showing only the items worth a reader's attention. Earnings releases, exhibit attachments and general disclosures are filed constantly and are left out. Filed is when the SEC received it; event is the date the company says the thing happened.
| Filed | Event date | What | Source |
|---|---|---|---|
| 2026-08-07 | 2026-07-31 | Directors or officers departed or appointed | filing |
| 2026-08-06 | 2026-07-31 | Directors or officers departed or appointed | filing |
What the insiders did
Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.
Officers and directors
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-07-01 | Crystal Adam | President, R&D | Sold | 27,000 | $798.9K ×2 |
| 2026-08-03 | Crystal Adam | President, R&D | Sold | 27,000 | $735.5K ×2 |
| 2026-10-01 | Crystal Adam | President, R&D | Sold | 27,000 | $660.8K ×2 |
| 2026-06-01 | Crystal Adam | President, R&D | Sold | 27,000 | $617.6K ×2 |
| 2026-09-01 | Crystal Adam | President, R&D | Sold | 27,000 | $603.9K |
| 2026-09-22 | Newcomb Jessica | Principal Accounting Officer | Sold | 8,200 | $198.6K ×3 |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 33 | $37.4M | 1,500,045 | 9 | 12 | 4 | 0.0% |
| Q2 2026 | 248 | $6.6B | 214,690,053 | 74 | 100 | 55 | 0.3% |
| Q1 2026 | 195 | $3.8B | 180,457,642 | 53 | 63 | 53 | 0.1% |
| Q4 2025 | 172 | $1.5B | 172,800,519 | 50 | 75 | 27 | 0.1% |
| Q3 2025 | 142 | $1.2B | 140,001,023 | 39 | 41 | 35 | 0.1% |
| Q2 2025 | 116 | $654.4M | 127,496,409 | 25 | 39 | 29 | 0.2% |
| Q1 2025 | 120 | $147.5M | 107,303,431 | 16 | 41 | 35 | 0.0% |
| Q4 2024 | 136 | $329.2M | 106,441,203 | 35 | 37 | 28 | 0.0% |
| Q3 2024 | 119 | $781.7M | 101,512,100 | 18 | 37 | 32 | 0.0% |
| Q2 2024 | 117 | $846.6M | 98,673,541 | 18 | 35 | 32 | 0.0% |
| Q1 2024 | 125 | $785.0M | 98,878,934 | 23 | 36 | 35 | 0.0% |
| Q4 2023 | 119 | $929.2M | 93,855,696 | 29 | 40 | 20 | 0.0% |
| Q3 2023 | 99 | $999.9M | 88,799,639 | 21 | 31 | 24 | 0.0% |
| Q2 2023 | 89 | $226.8M | 68,320,832 | 10 | 21 | 28 | 0.0% |
| Q1 2023 | 92 | $313.5M | 79,367,831 | 18 | 26 | 21 | 0.0% |
| Q4 2022 | 82 | $498.4M | 68,748,702 | 11 | 27 | 21 | 0.0% |
| Q3 2022 | 83 | $246.6M | 68,117,150 | 20 | 21 | 15 | 0.0% |
| Q2 2022 | 73 | $333.9M | 73,710,829 | 24 | 26 | 10 | 0.0% |
| Q1 2022 | 70 | $528.1M | 69,667,949 | 20 | 20 | 11 | 0.0% |
| Q4 2021 | 56 | $742.1M | 67,879,879 | 17 | 12 | 7 | 0.0% |
| Q3 2021 | 45 | $844.9M | 65,465,348 | 45 | 0 | 0 | 0.0% |