DaveManuel.com · Institutional Ownership · Who Owns It
TWIST BIOSCIENCE CORP (TWST)
Institutional ownership reported to the SEC as of Q2 2026, across 32 quarters.
342
Reporting holders
$7.9B
Reported value
121.8%
Of shares outstanding
0.5%
Calls
0.2%
Puts
+62
Holder change
Institutions report 76,404,439 shares against 62,707,424 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| BlackRock, Inc. | $600.2M | 5,833,891 | 0.01% | 8q | +5.0%+$28.8M |
| Artisan Partners Limited Partnership | $494.0M | 4,802,017 | 0.78% | 14q | -24.6%-$161.1M |
| FMR LLC | $483.8M | 4,703,044 | 0.02% | 31q | +148.8%+$289.4M |
| ARK Investment Management LLC | $468.1M | 4,549,803 | 3.04% | 29q | -28.3%-$184.5M |
| PRICE T ROWE ASSOCIATES INC /MD/ | $373.9M | 3,634,652 | 0.04% | 26q | +5069.8%+$366.7M |
| STATE STREET CORP | $332.6M | 3,232,532 | 0.01% | 31q | -11.9%-$45.1M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $290.6M | 2,824,989 | 0.01% | 2q | +6.6%+$18.1M |
| VANGUARD CAPITAL MANAGEMENT LLC | $277.7M | 2,699,280 | 0.01% | 2q | +2.3%+$6.2M |
| EdgePoint Investment Group Inc. | $259.4M | 2,521,635 | 1.96% | 6q | -53.2%-$294.3M |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | $223.7M | 2,174,594 | 0.67% | 26q | -58.7%-$318.4M |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | $219.8M | 2,136,400 | 1.01% | 9q | +49.6%+$72.9M |
| Invesco Ltd. | $198.4M | 1,928,229 | 0.02% | 26q | -11.2%-$25.1M |
| GEODE CAPITAL MANAGEMENT, LLC | $166.6M | 1,619,361 | 0.01% | 31q | +6.6%+$10.3M |
| Thrivent Financial for Lutherans | $147.5M | 1,433,503 | 0.25% | 8q | +9.2%+$12.4M |
| GOLDMAN SACHS GROUP INC | $144.9M | 1,408,418 | 0.01% | 29q | -17.4%-$30.6M |
| MORGAN STANLEY | $122.4M | 1,189,861 | 0.01% | 31q | +117.6%+$66.2M |
| D. E. Shaw & Co., Inc. | $122.0M | 1,185,605 | 0.06% | 3q | +2441.8%+$117.2M |
| BAILLIE GIFFORD & CO | $111.8M | 1,086,779 | 0.10% | 16q | -10.6%-$13.2M |
| Driehaus Capital Management LLC | $105.2M | 1,022,526 | 0.61% | 2q | +74.9%+$45.0M |
| Sumitomo Mitsui Trust Group, Inc. | $102.9M | 1,000,344 | 0.06% | 26q | -33.1%-$51.0M |
| Amova Asset Management Americas, Inc. | $102.8M | 999,734 | 1.33% | 26q | -33.2%-$51.1M |
| CITADEL ADVISORS LLC | $99.2M incl. $10.5M options CALL+PUT | 862,042 | 0.01% | 25q | -29.4%-$41.2M |
| BANK OF AMERICA CORP /DE/ | $94.9M | 922,647 | 0.01% | 31q | +57.9%+$34.8M |
| LOOMIS SAYLES & CO L P | $88.6M | 861,309 | 0.11% | 2q | +75.0%+$38.0M |
| Stephens Investment Management Group LLC | $78.9M | 767,364 | 0.85% | new | NEW |
| First Light Asset Management, LLC | $74.9M | 727,933 | 4.55% | 7q | -17.2%-$15.5M |
| VOYA INVESTMENT MANAGEMENT LLC | $69.1M | 671,866 | 0.06% | 29q | +6367.7%+$68.1M |
| FIL Ltd | $66.0M | 641,096 | 0.05% | new | NEW |
| T. Rowe Price Investment Management, Inc. | $61.5M | 597,935 | 0.04% | new | NEW |
| NORTHERN TRUST CORP | $60.9M | 591,688 | 0.01% | 31q | +12.1%+$6.6M |
| DIMENSIONAL FUND ADVISORS LP | $59.9M | 582,702 | 0.01% | 23q | -25.4%-$20.5M |
| WELLINGTON MANAGEMENT GROUP LLP | $58.5M | 568,347 | 0.01% | 11q | -23.1%-$17.5M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $58.0M | 563,782 | 0.01% | 26q | -31.6%-$26.8M |
| FRED ALGER MANAGEMENT, LLC | $57.4M | 558,157 | 0.19% | 11q | +482.7%+$47.6M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $57.3M | 557,131 | 0.01% | 31q | +3.7%+$2.1M |
| BNP PARIBAS FINANCIAL MARKETS | $56.2M | 546,647 | 0.02% | 29q | -9.5%-$5.9M |
| Nuveen, LLC | $53.7M | 522,043 | 0.01% | 6q | +77.8%+$23.5M |
| AMERICAN CENTURY COMPANIES INC | $50.1M | 487,031 | 0.02% | 13q | +1187.1%+$46.2M |
| Tao Capital Management LP | $49.3M | 478,815 | 2.54% | 27q | -42.2%-$36.0M |
| NEW YORK STATE COMMON RETIREMENT FUND | $47.5M | 462,145 | 0.06% | 29q | -31.4%-$21.8M |
| JENNISON ASSOCIATES LLC | $46.6M | 453,216 | 0.03% | 13q | -25.1%-$15.6M |
| VANGUARD FIDUCIARY TRUST CO | $45.6M | 443,474 | 0.01% | 2q | +4.8%+$2.1M |
| Allspring Global Investments Holdings, LLC | $42.8M | 418,129 | 0.07% | 2q | -8.2%-$3.8M |
| UBS Group AG | $42.5M | 413,127 | 0.01% | 24q | -8.7%-$4.1M |
| MARSHALL WACE, LLP | $40.8M | 396,912 | 0.03% | new | NEW |
| MILLENNIUM MANAGEMENT LLC | $39.5M incl. $3.8M options CALL+PUT | 347,148 | 0.01% | 29q | -1.0%-$393.0K |
| AMERIPRISE FINANCIAL INC | $35.0M | 340,072 | 0.01% | 31q | +921.2%+$31.6M |
| Granahan Investment Management, LLC | $32.4M | 314,882 | 1.15% | new | NEW |
| LORD, ABBETT & CO. LLC | $30.8M | 299,256 | 0.09% | 2q | +200.4%+$20.5M |
| FEDERATED HERMES, INC. | $30.7M | 298,113 | 0.04% | new | NEW |
| SEI INVESTMENTS CO | $30.3M | 294,931 | 0.03% | 24q | -16.8%-$6.1M |
| BLAIR WILLIAM & CO/IL | $26.4M | 256,556 | 0.07% | 23q | +346.8%+$20.5M |
| Trexquant Investment LP | $26.3M | 255,271 | 0.15% | 16q | +50.1%+$8.8M |
| USS Investment Management Ltd | $24.8M | 241,224 | 0.09% | new | NEW |
| JPMORGAN CHASE & CO | $20.5M | 205,248 | 0.00% | 31q | HELD |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | $20.2M | 196,496 | 0.13% | 13q | -19.5%-$4.9M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $19.8M incl. $16.4M options CALL+PUT | 32,880 | 0.00% | 26q | -63.6%-$34.6M |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | $19.7M | 191,845 | 1.26% | 9q | -32.6%-$9.5M |
| Bank of New York Mellon Corp | $19.7M | 191,698 | 0.00% | 30q | +6.0%+$1.1M |
| FIRST TRUST ADVISORS LP | $19.6M | 190,879 | 0.01% | 2q | +82.4%+$8.9M |
| JANE STREET GROUP, LLC | $18.6M incl. $9.8M options CALL+PUT | 86,284 | 0.00% | 15q | -85.6%-$111.2M |
| Freshford Capital Management, LLC | $18.3M | 177,449 | 6.25% | 3q | -31.5%-$8.4M |
| STATE OF MICHIGAN RETIREMENT SYSTEM | $18.3M | 177,401 | 0.08% | 24q | +15.8%+$2.5M |
| Metavasi Capital LP | $18.1M | 176,004 | 6.32% | 2q | +76.0%+$7.8M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $15.8M | 153,667 | 0.02% | 6q | +17.1%+$2.3M |
| NEUBERGER BERMAN GROUP LLC | $15.0M | 145,642 | 0.01% | 9q | +34.5%+$3.8M |
| ARMISTICE CAPITAL, LLC | $14.6M | 142,000 | 0.18% | new | NEW |
| PEREGRINE CAPITAL MANAGEMENT LLC | $14.3M | 138,970 | 0.46% | 5q | -36.9%-$8.3M |
| AQR CAPITAL MANAGEMENT LLC | $13.3M | 129,391 | 0.00% | 10q | +3.7%+$477.2K |
| Science & Technology Partners, L.P. | $13.3M | 129,228 | 2.24% | new | NEW |
| Legal & General Group Plc | $12.5M | 121,980 | 0.00% | 31q | -4.8%-$627.1K |
| PARNASSUS INVESTMENTS, LLC | $12.3M | 120,001 | 0.03% | new | NEW |
| PEAK6 LLC | $11.8M CALL | options only | 0.02% | new | OPTIONS |
| Swiss National Bank | $11.7M | 113,800 | 0.01% | 29q | -4.4%-$535.0K |
| OSTERWEIS CAPITAL MANAGEMENT INC | $11.5M | 111,458 | 0.54% | 3q | -47.2%-$10.3M |
| Atika Capital Management LLC | $11.1M | 108,000 | 0.73% | new | NEW |
| Soleus Capital Management, L.P. | $10.8M | 104,629 | 0.37% | 5q | -91.5%-$115.4M |
| TD Asset Management Inc | $10.7M | 103,986 | 0.01% | 2q | +1530.9%+$10.0M |
| Pictet Asset Management Holding SA | $10.7M | 108,267 | 0.01% | 11q | -41.8%-$7.7M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $10.3M | 100,108 | 0.01% | 9q | +26.6%+$2.2M |
| RHUMBLINE ADVISERS | $10.2M | 99,388 | 0.01% | 29q | +10.4%+$961.3K |
| Mawer Investment Management Ltd. | $10.2M | 99,251 | 0.07% | new | NEW |
| Russell Investments Group, Ltd. | $10.0M | 97,616 | 0.01% | 11q | +46.6%+$3.2M |
| TWO SIGMA INVESTMENTS, LP | $9.7M | 94,600 | 0.01% | 2q | +154.3%+$5.9M |
| DEUTSCHE BANK AG\ | $9.3M | 90,053 | 0.00% | 31q | +39.5%+$2.6M |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $9.2M | 89,273 | 0.01% | 3q | -41.5%-$6.5M |
| HRT FINANCIAL LP | $9.1M | 88,043 | 0.02% | new | NEW |
| ODDO BHF ASSET MANAGEMENT SAS | $9.1M | 88,006 | 0.42% | 8q | -39.7%-$6.0M |
| Vestmark Advisory Solutions, Inc. | $8.8M | 85,142 | 0.08% | 11q | -22.1%-$2.5M |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $8.2M | 79,848 | 0.01% | 29q | +223.8%+$5.7M |
| CITIGROUP INC | $8.0M | 77,626 | 0.00% | 31q | -83.1%-$39.4M |
| WELLS FARGO & COMPANY/MN | $8.0M | 77,336 | 0.00% | 31q | +151.0%+$4.8M |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $7.8M | 75,529 | 0.01% | 31q | +7.4%+$533.0K |
| Ensign Peak Advisors, Inc | $7.6M | 74,314 | 0.01% | 27q | -0.9%-$71.8K |
| ENVESTNET ASSET MANAGEMENT INC | $6.9M | 66,627 | 0.00% | 19q | +1.6%+$110.2K |
| LPL Financial LLC | $6.6M | 63,897 | 0.00% | 23q | +12.3%+$720.9K |
| Informed Momentum Co LLC | $6.4M | 62,564 | 0.57% | new | NEW |
| PRINCIPAL FINANCIAL GROUP INC | $6.0M | 58,508 | 0.00% | 2q | -45.2%-$5.0M |
| Man Group plc | $6.0M | 58,295 | 0.01% | 2q | -39.6%-$3.9M |
| POLEN CAPITAL MANAGEMENT LLC | $5.7M | 55,310 | 0.05% | 2q | +130.1%+$3.2M |
Showing the largest 100 of 342 reported holders.
What the company announced
Form 8-K filings from the last 120 days, showing only the items worth a reader's attention. Earnings releases, exhibit attachments and general disclosures are filed constantly and are left out. Filed is when the SEC received it; event is the date the company says the thing happened.
| Filed | Event date | What | Source |
|---|---|---|---|
| 2026-08-05 | 2026-08-04 | Material agreement entered | filing |
What the insiders did
Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.
Officers and directors
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-09-17 | Leproust Emily M. | Chief Executive Officer | Sold | 356,546 | $56.3M ×13 |
| 2026-08-10 | Leproust Emily M. | Chief Executive Officer | Sold | 113,318 | $14.2M |
| 2026-08-18 | Finn Patrick John | President and COO | Sold | 78,355 | $9.2M ×7 |
| 2026-10-02 | Leproust Emily M. | Chief Executive Officer | Sold | 45,736 | $8.6M |
| 2026-08-25 | Leproust Emily M. | Chief Executive Officer | Sold | 41,570 | $6.3M ×5 |
| 2026-10-02 | Finn Patrick John | President and COO | Sold | 25,714 | $4.9M |
| 2026-08-12 | Leproust Emily M. | Chief Executive Officer | Sold | 19,952 | $2.5M |
| 2026-06-15 | Green Paula | SVP of Human Resources | Sold | 26,137 | $2.1M ×2 |
| 2026-08-07 | CHESS ROBERT | Director | Sold | 18,417 | $2.0M |
| 2026-10-02 | Green Paula | SVP of Human Resources | Sold | 10,088 | $1.9M |
| 2026-08-19 | Cho Dennis | See Remarks | Sold | 14,205 | $1.8M |
| 2026-10-02 | Cho Dennis | See Remarks | Sold | 9,514 | $1.8M |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 88 | $263.5M | 1,366,988 | 31 | 21 | 23 | 0.0% |
| Q2 2026 | 342 | $7.9B | 76,404,439 | 92 | 99 | 101 | 0.7% |
| Q1 2026 | 280 | $3.7B | 77,067,893 | 62 | 75 | 85 | 0.5% |
| Q4 2025 | 247 | $2.4B | 75,009,547 | 44 | 70 | 73 | 0.3% |
| Q3 2025 | 240 | $2.1B | 74,783,080 | 34 | 94 | 61 | 0.3% |
| Q2 2025 | 245 | $2.6B | 71,312,964 | 33 | 73 | 86 | 0.2% |
| Q1 2025 | 264 | $2.7B | 69,764,698 | 45 | 85 | 79 | 0.2% |
| Q4 2024 | 249 | $3.1B | 66,360,958 | 25 | 87 | 80 | 0.3% |
| Q3 2024 | 246 | $3.1B | 68,551,025 | 31 | 88 | 71 | 0.3% |
| Q2 2024 | 264 | $3.4B | 69,270,962 | 62 | 88 | 78 | 0.6% |
| Q1 2024 | 239 | $2.5B | 73,003,952 | 40 | 75 | 71 | 0.7% |
| Q4 2023 | 223 | $2.7B | 72,716,723 | 39 | 56 | 73 | 1.0% |
| Q3 2023 | 197 | $1.4B | 66,342,011 | 27 | 55 | 62 | 0.6% |
| Q2 2023 | 195 | $1.4B | 68,182,479 | 29 | 71 | 47 | 0.8% |
| Q1 2023 | 202 | $1.0B | 66,345,409 | 34 | 78 | 42 | 0.8% |
| Q4 2022 | 198 | $1.5B | 60,772,383 | 27 | 72 | 55 | 0.8% |
| Q3 2022 | 213 | $2.8B | 79,956,993 | 38 | 67 | 55 | 0.3% |
| Q2 2022 | 194 | $2.8B | 80,613,876 | 33 | 78 | 42 | 0.4% |
| Q1 2022 | 206 | $3.8B | 77,536,006 | 26 | 93 | 47 | 0.3% |
| Q4 2021 | 231 | $5.4B | 69,244,732 | 31 | 77 | 69 | 0.6% |
| Q3 2021 | 232 | $15.5B | 145,064,576 | 29 | 90 | 54 | 0.2% |
| Q2 2021 | 241 | $17.6B | 131,625,337 | 47 | 89 | 61 | 0.2% |
| Q1 2021 | 236 | $9.0B | 73,086,347 | 47 | 87 | 72 | 0.6% |
| Q4 2020 | 226 | $7.5B | 52,619,218 | 51 | 65 | 67 | 1.0% |
| Q3 2020 | 192 | $3.7B | 48,817,793 | 60 | 55 | 55 | 0.4% |
| Q2 2020 | 145 | $2.2B | 48,859,769 | 40 | 58 | 34 | 0.3% |
| Q1 2020 | 118 | $1.7B | 55,104,433 | 42 | 42 | 22 | 0.0% |
| Q4 2019 | 91 | $576.4M | 27,448,765 | 18 | 32 | 20 | 0.0% |
| Q3 2019 | 82 | $7.7B | 322,765,333 | 11 | 44 | 11 | 0.0% |
| Q2 2019 | 82 | $9.1B | 315,225,690 | 40 | 31 | 3 | 0.0% |
| Q1 2019 | 48 | $137.7M | 6,003,768 | 7 | 15 | 16 | 0.0% |
| Q4 2018 | 47 | $143.2M | 6,443,525 | 3 | 0 | 0 | 0.0% |