VERTEX PHARMACEUTICALS INC (VRTX)
Institutional ownership reported to the SEC as of Q2 2026, across 32 quarters.
Institutions report 242,283,522 shares against 253,460,924 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. A figure this high can overstate: where an adviser and a sub-adviser both report the same shares, both are counted.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| Capital World Investors | $13.0B | 26,115,014 | 1.53% | 31q | +2.9%+$371.0M |
| BlackRock, Inc. | $12.0B | 24,109,373 | 0.18% | 8q | +0.6%+$69.5M |
| Capital Research Global Investors | $9.7B | 19,490,637 | 1.35% | 14q | -7.7%-$812.3M |
| VANGUARD CAPITAL MANAGEMENT LLC | $8.2B | 16,580,713 | 0.18% | 2q | HELD |
| STATE STREET CORP | $5.9B | 11,871,459 | 0.17% | 31q | +1.2%+$70.2M |
| Invesco Ltd. | $4.0B | 8,043,052 | 0.32% | 31q | +1.9%+$74.7M |
| JPMORGAN CHASE & CO | $3.3B incl. $78.4M options CALL+PUT | 6,517,600 | 0.18% | 31q | -7.3%-$263.8M |
| GEODE CAPITAL MANAGEMENT, LLC | $3.0B | 6,017,848 | 0.16% | 31q | -2.0%-$60.2M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $2.4B | 4,878,987 | 0.11% | 2q | -5.2%-$132.4M |
| Capital International Investors | $2.3B | 4,695,144 | 0.48% | 7q | -8.4%-$214.1M |
| LOOMIS SAYLES & CO L P | $1.9B | 3,920,953 | 2.44% | 27q | -2.1%-$41.2M |
| FRANKLIN RESOURCES INC | $1.7B | 3,347,253 | 0.36% | 31q | +507.3%+$1.4B |
| WELLINGTON MANAGEMENT GROUP LLP | $1.6B | 3,247,658 | 0.28% | 31q | +1.1%+$17.4M |
| MORGAN STANLEY | $1.6B | 3,242,139 | 0.09% | 35q | +1.7%+$26.5M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $1.5B | 3,086,683 | 0.28% | 31q | +1.0%+$14.5M |
| BANK OF AMERICA CORP /DE/ | $1.5B | 3,039,178 | 0.10% | 31q | +5.6%+$80.0M |
| JENNISON ASSOCIATES LLC | $1.5B | 2,998,530 | 0.89% | 31q | +9.4%+$128.4M |
| NORGES BANK | $1.5B | 2,971,681 | 0.15% | 32q | -6.5%-$101.8M |
| ALLIANCEBERNSTEIN L.P. | $1.3B | 3,019,315 | 0.45% | 31q | -22.8%-$398.1M |
| AMERIPRISE FINANCIAL INC | $1.3B | 2,604,822 | 0.26% | 31q | -1.1%-$14.2M |
| GOLDMAN SACHS GROUP INC | $1.3B incl. $24.9M options CALL+PUT | 2,481,761 | 0.11% | 31q | +2.6%+$32.4M |
| NORTHERN TRUST CORP | $1.2B | 2,486,478 | 0.14% | 31q | -3.0%-$38.6M |
| Clearbridge Investments, LLC | $1.2B | 2,342,915 | 0.96% | 31q | -13.3%-$177.9M |
| VICTORY CAPITAL MANAGEMENT INC | $1.1B | 2,173,152 | 0.61% | 31q | +15.1%+$141.4M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $1.0B | 2,041,282 | 0.13% | 31q | +6.3%+$59.8M |
| Legal & General Group Plc | $928.9M | 1,870,015 | 0.19% | 31q | -4.4%-$42.6M |
| PRICE T ROWE ASSOCIATES INC /MD/ | $858.6M | 1,728,421 | 0.09% | 31q | -1.8%-$15.7M |
| Bank of New York Mellon Corp | $830.8M | 1,672,623 | 0.14% | 31q | +5.4%+$42.8M |
| DEUTSCHE BANK AG\ | $784.4M | 1,579,110 | 0.23% | 34q | +2.7%+$20.6M |
| Amundi | $768.2M | 1,546,509 | 0.18% | 21q | +5.0%+$36.8M |
| Assenagon Asset Management S.A. | $754.6M | 1,519,128 | 0.47% | 31q | +182.8%+$487.7M |
| FMR LLC | $723.8M | 1,457,158 | 0.03% | 31q | -27.9%-$279.7M |
| VANGUARD FIDUCIARY TRUST CO | $708.0M | 1,425,390 | 0.16% | 2q | -2.8%-$20.0M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $662.5M incl. $590.9M options CALL+PUT | 144,174 | 0.05% | 31q | +613.0%+$569.6M |
| Jupiter Topco LLC | $625.8M | 1,259,997 | 0.26% | new | FIRST |
| DIMENSIONAL FUND ADVISORS LP | $580.7M | 1,168,956 | 0.11% | 31q | +18.2%+$89.2M |
| WCM INVESTMENT MANAGEMENT, LLC | $575.6M | 1,152,094 | 1.04% | 7q | +2.7%+$15.4M |
| Nuveen, LLC | $537.3M | 1,081,685 | 0.13% | 6q | HELD |
| ROYAL BANK OF CANADA | $486.9M | 980,259 | 0.07% | 31q | -11.8%-$65.4M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $446.0M | 897,893 | 0.45% | 31q | +5.9%+$24.8M |
| CITADEL ADVISORS LLC | $441.9M incl. $188.4M options CALL+PUT | 510,430 | 0.05% | 31q | +50.4%+$148.2M |
| UBS Group AG | $399.1M incl. $45.3M options CALL+PUT | 712,259 | 0.05% | 31q | +12.9%+$45.7M |
| WELLS FARGO & COMPANY/MN | $372.3M | 749,528 | 0.06% | 31q | +0.6%+$2.3M |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $366.8M | 738,378 | 0.16% | 5q | +15.6%+$49.4M |
| BARCLAYS PLC | $364.2M | 733,274 | 0.07% | 31q | +10.6%+$34.8M |
| CITIGROUP INC | $361.3M incl. $10.1M options CALL+PUT | 706,968 | 0.12% | 31q | +3.5%+$12.3M |
| Swiss National Bank | $356.4M | 717,440 | 0.19% | 31q | -3.6%-$13.5M |
| HSBC HOLDINGS PLC | $335.8M | 676,247 | 0.14% | 31q | +3.2%+$10.3M |
| Mitsubishi UFJ Asset Management Co., Ltd. | $321.5M | 647,193 | 0.18% | 31q | +8.3%+$24.7M |
| Hudson Bay Capital Management LP | $318.1M incl. $124.2M options PUT | 390,440 | 0.86% | 9q | +767.6%+$281.5M |
| AQR CAPITAL MANAGEMENT LLC | $305.0M | 616,170 | 0.11% | 31q | +260.3%+$220.3M |
| Sumitomo Mitsui Trust Group, Inc. | $304.0M | 611,907 | 0.17% | 31q | HELD |
| AMERICAN CENTURY COMPANIES INC | $288.6M | 580,901 | 0.13% | 31q | -28.6%-$115.4M |
| Bellevue Group AG | $287.4M | 578,634 | 6.05% | 31q | -15.1%-$51.3M |
| MILLENNIUM MANAGEMENT LLC | $280.1M incl. $47.4M options CALL+PUT | 468,410 | 0.10% | 31q | +1419.7%+$261.6M |
| NEUBERGER BERMAN GROUP LLC | $277.9M | 559,445 | 0.18% | 31q | +1.4%+$3.9M |
| RAYMOND JAMES FINANCIAL INC | $276.6M | 556,876 | 0.07% | 7q | +25.3%+$55.8M |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $275.2M | 554,085 | 0.21% | 31q | HELD |
| Vanguard Global Advisers, LLC | $271.9M | 547,463 | 0.13% | 2q | -1.5%-$4.1M |
| MARSHALL WACE, LLP | $270.7M incl. $546.4K options PUT | 543,897 | 0.21% | 17q | +71.5%+$112.9M |
| Pictet Asset Management Holding SA | $268.3M | 539,255 | 0.26% | 12q | +59.7%+$100.4M |
| National Pension Service | $268.0M | 539,530 | 0.17% | 31q | +1.4%+$3.7M |
| EDGEWOOD MANAGEMENT LLC | $263.8M | 531,003 | 2.72% | 31q | -41.3%-$185.8M |
| SG Americas Securities, LLC | $260.3M incl. $105.0K options CALL | 523,720 | 0.15% | 31q | +819.1%+$231.9M |
| Life Cycle Investment Partners Ltd | $255.4M | 514,179 | 1.19% | 3q | +16.8%+$36.6M |
| VOYA INVESTMENT MANAGEMENT LLC | $250.4M | 505,219 | 0.22% | 31q | -4.1%-$10.8M |
| VANGUARD ASSET MANAGEMENT, Ltd | $245.5M | 494,186 | 0.17% | 2q | +11.8%+$25.8M |
| ENVESTNET ASSET MANAGEMENT INC | $242.2M | 487,627 | 0.06% | 31q | -3.2%-$7.9M |
| DekaBank Deutsche Girozentrale | $225.3M | 506,457 | 0.38% | 31q | HELD |
| NATIXIS ADVISORS, LLC | $222.8M | 448,631 | 0.25% | 31q | -19.0%-$52.4M |
| California Public Employees Retirement System | $222.3M | 447,499 | 0.13% | 31q | -11.1%-$27.8M |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $214.6M | 423,049 | 0.07% | 31q | +29.2%+$48.5M |
| BANK OF MONTREAL /CAN/ | $212.3M | 427,448 | 0.07% | 31q | +9.5%+$18.4M |
| Chevy Chase Trust Holdings, LLC | $201.8M | 406,303 | 0.52% | 31q | HELD |
| Robeco Institutional Asset Management B.V. | $200.9M | 404,396 | 0.25% | 38q | +0.7%+$1.4M |
| RHUMBLINE ADVISERS | $196.9M | 396,380 | 0.15% | 31q | -6.3%-$13.3M |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $195.7M | 393,964 | 0.27% | 31q | +56.3%+$70.5M |
| PRINCIPAL FINANCIAL GROUP INC | $193.5M | 389,511 | 0.10% | 31q | -8.7%-$18.4M |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $190.5M | 383,491 | 0.18% | 31q | +2.7%+$5.0M |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $189.1M | 380,762 | 0.36% | 31q | +1.0%+$1.9M |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | $178.5M | 359,332 | 0.14% | 32q | -1.4%-$2.6M |
| CANADA PENSION PLAN INVESTMENT BOARD | $176.4M | 355,082 | 0.10% | 31q | +86.8%+$82.0M |
| Russell Investments Group, Ltd. | $167.5M | 336,990 | 0.15% | 31q | -8.3%-$15.3M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $160.7M | 323,752 | 0.25% | 7q | -4.3%-$7.2M |
| RENAISSANCE TECHNOLOGIES LLC | $159.0M | 320,008 | 0.22% | 31q | -24.1%-$50.5M |
| Bank Julius Baer & Co. Ltd, Zurich | $158.9M | 319,371 | 0.41% | 26q | +0.6%+$977.8K |
| AMF Tjanstepension AB | $156.4M | 314,765 | 0.93% | 9q | +0.6%+$918.0K |
| JANE STREET GROUP, LLC | $155.2M incl. $149.6M options CALL+PUT | 11,231 | 0.01% | 31q | -90.9%-$1.5B |
| BNP PARIBAS FINANCIAL MARKETS | $144.4M incl. $14.2M options CALL+PUT | 262,258 | 0.05% | 31q | -36.9%-$84.5M |
| FIRST TRUST ADVISORS LP | $143.6M | 289,179 | 0.08% | 31q | -5.6%-$8.6M |
| LPL Financial LLC | $143.6M | 289,111 | 0.03% | 31q | +7.9%+$10.5M |
| ProShare Advisors LLC | $143.0M | 287,847 | 0.21% | 31q | -22.9%-$42.6M |
| TWO SIGMA INVESTMENTS, LP | $142.8M incl. $1.2M options CALL+PUT | 285,000 | 0.10% | 3q | -24.6%-$46.7M |
| Swedbank AB | $140.3M | 282,444 | 0.12% | 21q | +4.0%+$5.4M |
| NEW YORK STATE COMMON RETIREMENT FUND | $137.9M | 277,614 | 0.17% | 31q | -5.1%-$7.4M |
| NATIONAL BANK OF CANADA /FI/ | $137.8M incl. $52.0M options CALL | 172,898 | 0.10% | 19q | -36.5%-$79.1M |
| BAILLIE GIFFORD & CO | $135.4M | 272,561 | 0.12% | 9q | +36.7%+$36.3M |
| Cerity Partners LLC | $127.1M | 255,874 | 0.15% | 31q | -13.7%-$20.3M |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | $124.3M | 250,189 | 0.43% | 31q | -19.7%-$30.6M |
| ROYAL LONDON ASSET MANAGEMENT LTD | $119.9M | 241,280 | 0.22% | 32q | -4.3%-$5.4M |
Showing the largest 100 of 1,780 reported holders. The count of 1,779 above leaves out 1 position whose reported value failed our price check; it is listed here as filed.
Q2 2026 in brief
In Q2 2026, 1,779 managers that file Form 13F reported holding Vertex Pharmaceuticals Inc (VRTX), $121.8B in all, or about 96% of the shares outstanding. 193 managers opened a position and 125 sold out completely, against 1,711 holders the quarter before. Largest holders: Capital World Investors, Blackrock, Inc. and Capital Research Global Investors. Largest new positions: Harvest Portfolios Group Inc. ($73.6M), National Bank Of Canada /Fi/ ($52.0M) and Mn Services Vermogensbeheer B.V. ($36.8M).
Q2 2026 is the latest quarter whose 13F deadline has passed. A 13F shows long US stock positions at quarter end, filed up to 45 days later; an adviser and a sub-adviser can both report the same shares.
What the company announced
Form 8-K filings from the last 120 days, showing only the items worth a reader's attention. Earnings releases, exhibit attachments and general disclosures are filed constantly and are left out. Filed is when the SEC received it; event is the date the company says the thing happened.
| Filed | Event date | What | Source |
|---|---|---|---|
| 2026-10-20 | 2026-10-20 | Directors or officers departed or appointed | filing |
| 2026-09-01 | 2026-08-27 | Directors or officers departed or appointed | filing |
What the insiders did
Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.
Officers and directors
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-05-12 | Bozic Carmen | EVP and CMO | Sold | 6,988 | $3.1M |
| 2026-06-15 | Bozic Carmen | EVP and CMO | Sold | 4,062 | $1.8M |
| 2026-05-29 | Bozic Carmen | EVP and CMO | Sold | 1,974 | $888.3K |
| 2026-07-02 | McKechnie Duncan | EVP, Chief Commercial Officer | Sold | 1,541 | $799.8K |
| 2026-07-02 | Tatsis Ourania | EVP, Chief Reg. & Quality Off. | Sold | 1,500 | $787.5K |
| 2026-06-05 | Bozic Carmen | EVP and CMO | Sold | 1,745 | $785.2K |
| 2026-05-15 | Bozic Carmen | EVP and CMO | Sold | 1,354 | $614.0K |
| 2026-06-18 | Bozic Carmen | EVP and CMO | Sold | 1,020 | $471.4K |
| 2026-07-01 | Liu Joy | EVP and Chief Legal Officer | Sold | 828 | $416.2K |
| 2026-06-01 | Liu Joy | EVP and Chief Legal Officer | Sold | 828 | $364.2K |
| 2026-06-26 | Bozic Carmen | EVP and CMO | Sold | 596 | $287.6K |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 658 | $4.8B | 9,250,013 | 54 | 257 | 187 | 0.0% |
| Q2 2026 | 1,779 | $121.8B | 242,283,522 | 177 | 680 | 579 | 1.3% |
| Q1 2026 | 1,711 | $107.7B | 237,785,063 | 127 | 636 | 577 | 1.4% |
| Q4 2025 | 1,688 | $111.4B | 242,345,113 | 173 | 586 | 528 | 1.4% |
| Q3 2025 | 1,533 | $94.9B | 238,884,916 | 131 | 527 | 583 | 1.5% |
| Q2 2025 | 1,580 | $109.4B | 242,445,012 | 100 | 577 | 571 | 1.4% |
| Q1 2025 | 1,627 | $118.1B | 240,792,159 | 185 | 607 | 545 | 1.2% |
| Q4 2024 | 1,576 | $96.8B | 236,766,706 | 106 | 519 | 580 | 1.5% |
| Q3 2024 | 1,557 | $114.0B | 241,724,206 | 104 | 581 | 543 | 1.5% |
| Q2 2024 | 1,561 | $114.7B | 241,307,689 | 156 | 621 | 493 | 1.4% |
| Q1 2024 | 1,499 | $104.7B | 247,249,149 | 157 | 576 | 479 | 1.5% |
| Q4 2023 | 1,449 | $101.3B | 244,140,160 | 148 | 528 | 457 | 1.9% |
| Q3 2023 | 1,288 | $83.5B | 236,340,028 | 74 | 487 | 421 | 1.6% |
| Q2 2023 | 1,287 | $84.3B | 237,516,370 | 122 | 453 | 456 | 1.0% |
| Q1 2023 | 1,215 | $81.1B | 255,933,593 | 98 | 431 | 441 | 1.0% |
| Q4 2022 | 1,223 | $69.2B | 236,769,374 | 131 | 401 | 434 | 1.2% |
| Q3 2022 | 1,112 | $171.1B | 773,480,355 | 105 | 401 | 382 | 0.6% |
| Q2 2022 | 1,101 | $156.8B | 849,883,289 | 122 | 341 | 419 | 0.8% |
| Q1 2022 | 1,068 | $122.5B | 687,758,171 | 147 | 387 | 362 | 1.4% |
| Q4 2021 | 1,027 | $126.8B | 645,302,787 | 140 | 329 | 349 | 17.5% |
| Q3 2021 | 931 | $125.4B | 636,957,357 | 89 | 333 | 330 | 26.1% |
| Q2 2021 | 974 | $179.8B | 881,810,325 | 109 | 377 | 320 | 20.2% |
| Q1 2021 | 987 | $182.6B | 1,124,095,995 | 133 | 406 | 292 | 7.8% |
| Q4 2020 | 965 | $88.7B | 555,982,225 | 113 | 369 | 303 | 0.9% |
| Q3 2020 | 946 | $131.0B | 714,739,850 | 81 | 378 | 305 | 0.4% |
| Q2 2020 | 963 | $146.5B | 696,326,519 | 162 | 390 | 265 | 0.4% |
| Q1 2020 | 859 | $139.1B | 699,554,978 | 129 | 315 | 268 | 0.4% |
| Q4 2019 | 810 | $131.9B | 688,123,778 | 112 | 254 | 250 | 0.6% |
| Q3 2019 | 708 | $109.2B | 748,810,121 | 58 | 265 | 225 | 0.5% |
| Q2 2019 | 716 | $113.3B | 782,234,090 | 65 | 260 | 231 | 0.7% |
| Q1 2019 | 743 | $127.2B | 873,986,419 | 83 | 278 | 213 | 0.4% |
| Q4 2018 | 712 | $125.7B | 824,974,073 | 9 | 12 | 12 | 0.6% |