DaveManuel.com · Institutional Ownership · Who Owns It
WAVE LIFE SCIENCES LTD (WVE)
Institutional ownership reported to the SEC as of Q2 2026, across 32 quarters.
244
Reporting holders
$1.1B
Reported value
92.7%
Of shares outstanding
0.3%
Calls
0.1%
Puts
+10
Holder change
Institutions report 182,644,731 shares against 197,048,175 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. A figure this high can overstate: where an adviser and a sub-adviser both report the same shares, both are counted.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $156.7M | 26,975,505 | 1.36% | 31q | HELD |
| BlackRock, Inc. | $111.6M | 19,202,461 | 0.00% | 8q | +36.0%+$29.5M |
| GSK plc | $106.0M | 18,245,691 | 17.60% | 3q | HELD |
| MAVERICK CAPITAL LTD | $59.7M | 10,278,115 | 0.53% | 22q | +1.1%+$678.1K |
| Driehaus Capital Management LLC | $31.6M | 5,443,143 | 0.18% | 11q | HELD |
| PRIMECAP MANAGEMENT CO/CA/ | $31.1M | 5,354,622 | 0.02% | 28q | +10.8%+$3.0M |
| 683 Capital Management, LLC | $28.8M | 4,950,000 | 1.41% | 21q | +1.0%+$290.5K |
| FMR LLC | $28.6M | 4,922,477 | 0.00% | 18q | -5.2%-$1.6M |
| STATE STREET CORP | $28.1M | 4,839,317 | 0.00% | 31q | +31.7%+$6.8M |
| READYSTATE ASSET MANAGEMENT LP | $27.5M | 4,727,139 | 0.94% | new | NEW |
| M28 Capital Management LP | $26.7M | 4,588,284 | 56.53% | 19q | HELD |
| GEODE CAPITAL MANAGEMENT, LLC | $22.5M | 3,869,998 | 0.00% | 31q | +8.1%+$1.7M |
| TWO SIGMA INVESTMENTS, LP | $21.5M | 3,707,686 | 0.02% | 11q | +97.4%+$10.6M |
| ALGERT GLOBAL LLC | $16.4M | 2,817,615 | 0.19% | 3q | +114.2%+$8.7M |
| Qube Research & Technologies Ltd | $16.1M | 2,776,000 | 0.01% | 2q | +1680.4%+$15.2M |
| Squarepoint Ops LLC | $14.8M | 2,541,442 | 0.02% | 7q | +73.8%+$6.3M |
| MORGAN STANLEY | $14.1M | 2,422,705 | 0.00% | 35q | +78.0%+$6.2M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $12.3M | 2,110,751 | 0.00% | 2q | +79.5%+$5.4M |
| Pfizer Inc | $10.9M | 1,875,000 | 6.42% | 7q | HELD |
| MILLENNIUM MANAGEMENT LLC | $10.5M | 1,811,282 | 0.00% | 25q | +86.3%+$4.9M |
| PRICE T ROWE ASSOCIATES INC /MD/ | $10.5M | 1,806,467 | 0.00% | 31q | -79.2%-$40.1M |
| D. E. Shaw & Co., Inc. | $10.3M | 1,772,228 | 0.00% | 3q | +2351.0%+$9.9M |
| VANGUARD CAPITAL MANAGEMENT LLC | $10.2M | 1,751,403 | 0.00% | 2q | +8.7%+$810.8K |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $9.9M | 1,746,643 | 0.01% | 6q | +21.2%+$1.7M |
| DIMENSIONAL FUND ADVISORS LP | $9.9M | 1,707,809 | 0.00% | new | NEW |
| RENAISSANCE TECHNOLOGIES LLC | $9.9M | 1,704,520 | 0.01% | 3q | +185.4%+$6.4M |
| AQR CAPITAL MANAGEMENT LLC | $9.6M | 1,648,045 | 0.00% | 4q | +265.3%+$7.0M |
| GOLDMAN SACHS GROUP INC | $9.4M | 1,622,342 | 0.00% | 31q | +17.3%+$1.4M |
| Point72 Asset Management, L.P. | $8.6M incl. $16.3K options CALL | 1,484,989 | 0.01% | 2q | HELD |
| FEDERATED HERMES, INC. | $8.5M | 1,466,234 | 0.01% | 7q | -72.4%-$22.4M |
| RTW INVESTMENTS, LP | $7.8M | 1,350,000 | 0.07% | 8q | HELD |
| NORTHERN TRUST CORP | $7.3M | 1,253,500 | 0.00% | 31q | +5.4%+$373.4K |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $7.1M | 1,224,445 | 0.00% | 31q | +3.8%+$262.4K |
| EMERALD ADVISERS, LLC | $7.1M | 1,223,965 | 0.17% | 9q | -3.0%-$216.2K |
| MARSHALL WACE, LLP | $5.8M | 999,533 | 0.00% | 2q | -44.2%-$4.6M |
| Pictet Asset Management Holding SA | $5.3M | 917,409 | 0.01% | 9q | -20.2%-$1.3M |
| VANGUARD FIDUCIARY TRUST CO | $5.2M | 887,677 | 0.00% | 2q | +1.0%+$51.4K |
| Aberdeen Group plc | $5.1M | 876,458 | 0.01% | 2q | +59.4%+$1.9M |
| EMERALD MUTUAL FUND ADVISERS TRUST | $4.9M | 847,999 | 0.17% | 9q | +4.1%+$194.5K |
| BAKER BROS. ADVISORS LP | $4.8M | 822,638 | 0.02% | 8q | HELD |
| BNP PARIBAS FINANCIAL MARKETS | $4.7M | 811,057 | 0.00% | 31q | +188.6%+$3.1M |
| CAPITAL FUND MANAGEMENT S.A. | $4.3M | 734,746 | 0.02% | 2q | +300.8%+$3.2M |
| Walleye Capital LLC | $3.7M incl. $329.4K options CALL+PUT | 585,453 | 0.01% | 8q | +18.6%+$585.9K |
| SPHERA FUNDS MANAGEMENT LTD. | $3.7M | 638,272 | 0.48% | 4q | +16.4%+$522.9K |
| CITADEL ADVISORS LLC | $3.6M incl. $805.3K options CALL+PUT | 480,154 | 0.00% | 11q | -78.2%-$12.9M |
| JPMORGAN CHASE & CO | $3.5M | 618,172 | 0.00% | 31q | -7.8%-$298.3K |
| Y-Intercept (Hong Kong) Ltd | $3.5M | 610,094 | 0.07% | 2q | +288.6%+$2.6M |
| Susquehanna Portfolio Strategies, LLC | $3.5M | 608,194 | 0.06% | 6q | +210.6%+$2.4M |
| TANG CAPITAL MANAGEMENT LLC | $3.5M | 600,000 | 0.16% | 3q | HELD |
| UBS Group AG | $3.5M incl. $531.0K options CALL | 505,237 | 0.00% | 31q | -6.3%-$231.6K |
| Nuveen, LLC | $3.2M | 549,282 | 0.00% | 6q | -16.5%-$630.0K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $3.1M incl. $1.4M options CALL+PUT | 299,400 | 0.00% | 30q | +15.2%+$410.9K |
| BANK OF AMERICA CORP /DE/ | $3.0M | 517,054 | 0.00% | 31q | +118.4%+$1.6M |
| Man Group plc | $2.9M | 505,456 | 0.00% | 5q | +689.3%+$2.6M |
| Jump Financial, LLC | $2.6M | 452,502 | 0.02% | 3q | +25.7%+$537.1K |
| XTX Topco Ltd | $2.6M | 439,933 | 0.03% | 2q | +300.4%+$1.9M |
| KENNEDY CAPITAL MANAGEMENT LLC | $2.5M | 429,121 | 0.04% | new | NEW |
| WELLINGTON MANAGEMENT GROUP LLP | $2.5M | 423,005 | 0.00% | 15q | +13.2%+$285.9K |
| Bank of New York Mellon Corp | $2.4M | 416,579 | 0.00% | 31q | +15.3%+$321.7K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $2.4M | 408,894 | 0.00% | 7q | -1.6%-$38.1K |
| Connor, Clark & Lunn Investment Management Ltd. | $2.4M | 406,478 | 0.00% | 3q | -34.9%-$1.3M |
| Trexquant Investment LP | $2.2M | 380,169 | 0.01% | 3q | -65.1%-$4.1M |
| HSBC HOLDINGS PLC | $2.2M | 370,449 | 0.00% | new | NEW |
| Woodline Partners LP | $2.0M | 350,531 | 0.01% | 3q | HELD |
| Ishara Investments LP | $1.9M | 328,000 | 1.40% | new | NEW |
| BARCLAYS PLC | $1.8M | 309,580 | 0.00% | 16q | +63.1%+$695.5K |
| Russell Investments Group, Ltd. | $1.6M | 276,818 | 0.00% | 10q | +376.8%+$1.3M |
| PLATINUM INVESTMENT MANAGEMENT LTD | $1.6M | 275,269 | 0.39% | 31q | HELD |
| Swiss National Bank | $1.5M | 260,600 | 0.00% | 11q | +18.6%+$237.6K |
| ExodusPoint Capital Management, LP | $1.5M | 251,072 | 0.01% | new | NEW |
| Privium Fund Management B.V. | $1.4M | 241,010 | 0.26% | 8q | HELD |
| F/m Investments LLC | $1.4M | 235,085 | 0.07% | 7q | +42.5%+$407.7K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $1.3M | 230,484 | 0.00% | 9q | +53.3%+$465.5K |
| Newtyn Management, LLC | $1.2M | 215,000 | 0.16% | 17q | -28.3%-$493.8K |
| Invesco Ltd. | $1.2M | 200,306 | 0.00% | 13q | HELD |
| TD Asset Management Inc | $1.1M | 194,026 | 0.00% | 12q | -42.7%-$841.3K |
| ALPS ADVISORS INC | $1.1M | 193,766 | 0.01% | new | NEW |
| RHUMBLINE ADVISERS | $1.1M | 193,667 | 0.00% | 13q | +15.6%+$151.9K |
| Sofinnova Investments, Inc. | $1.1M | 189,253 | 0.06% | 5q | HELD |
| GSA CAPITAL PARTNERS LLP | $1.1M | 185,959 | 0.07% | 2q | -34.2%-$562.0K |
| Elmind Capital, LP | $1.0M | 177,846 | 0.26% | 3q | HELD |
| Duquesne Family Office LLC | $1.0M | 173,000 | 0.02% | 3q | HELD |
| ADAR1 Capital Management, LLC | $929.6K | 160,000 | 0.04% | 2q | +256.3%+$668.7K |
| ALLIANCEBERNSTEIN L.P. | $904.3K | 124,730 | 0.00% | 11q | HELD |
| WELLS FARGO & COMPANY/MN | $896.0K | 154,211 | 0.00% | 19q | +13.2%+$104.8K |
| Burkehill Global Management, LP | $871.5K | 150,000 | 0.03% | 3q | HELD |
| DEUTSCHE BANK AG\ | $854.7K | 147,101 | 0.00% | 13q | +28.9%+$191.7K |
| BOOTHBAY FUND MANAGEMENT, LLC | $842.5K | 145,000 | 0.01% | 10q | -9.6%-$89.0K |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $836.7K | 144,009 | 0.00% | 13q | -40.2%-$563.4K |
| STATE OF WISCONSIN INVESTMENT BOARD | $831.0K | 143,026 | 0.00% | 7q | +32.2%+$202.5K |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $817.8K | 140,752 | 0.00% | 13q | -3.1%-$25.9K |
| CITIGROUP INC | $726.5K | 125,051 | 0.00% | 31q | -75.1%-$2.2M |
| James J. Burns & Company, LLC | $667.0K | 114,800 | 0.07% | 9q | HELD |
| IEQ CAPITAL, LLC | $618.5K | 106,446 | 0.00% | 2q | +372.4%+$487.5K |
| SIMPLEX TRADING, LLC | $611.7K incl. $520.0K options CALL+PUT | 15,792 | 0.00% | 8q | -82.3%-$2.8M |
| Cetera Investment Advisers | $609.3K | 104,878 | 0.00% | new | NEW |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $608.3K | 104,705 | 0.00% | new | NEW |
| VANGUARD ASSET MANAGEMENT, Ltd | $604.2K | 103,995 | 0.00% | 2q | +39.2%+$170.2K |
| Mariner, LLC | $593.8K | 102,195 | 0.00% | 2q | +389.2%+$472.4K |
| Bridgefront Capital, LLC | $589.4K | 101,454 | 0.16% | 2q | +735.3%+$518.9K |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-10-27 | 13G/A | BlackRock, Inc. | 0.0% |
| 2026-10-27 | 13G | BlackRock, Inc. | 6.8% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 34 | $7.8M | 2,119,351 | 34 | 0 | 2 | 0.0% |
| Q2 2026 | 244 | $1.1B | 182,644,731 | 50 | 98 | 53 | 0.4% |
| Q1 2026 | 234 | $1.3B | 172,661,191 | 48 | 102 | 47 | 3.0% |
| Q4 2025 | 220 | $3.2B | 182,765,659 | 64 | 74 | 49 | 2.9% |
| Q3 2025 | 190 | $1.1B | 144,540,330 | 30 | 56 | 60 | 1.3% |
| Q2 2025 | 177 | $907.0M | 138,965,957 | 22 | 82 | 38 | 0.4% |
| Q1 2025 | 197 | $1.1B | 131,484,315 | 32 | 78 | 47 | 0.6% |
| Q4 2024 | 184 | $1.6B | 128,734,148 | 38 | 75 | 39 | 0.9% |
| Q3 2024 | 163 | $992.8M | 120,740,124 | 37 | 59 | 39 | 0.3% |
| Q2 2024 | 144 | $477.4M | 95,580,819 | 33 | 48 | 43 | 0.1% |
| Q1 2024 | 132 | $587.7M | 95,145,665 | 31 | 52 | 33 | 0.1% |
| Q4 2023 | 117 | $473.2M | 93,221,198 | 38 | 48 | 10 | 0.4% |
| Q3 2023 | 85 | $417.7M | 72,598,087 | 12 | 26 | 26 | 0.1% |
| Q2 2023 | 81 | $263.0M | 72,165,936 | 25 | 21 | 19 | 0.1% |
| Q1 2023 | 74 | $308.5M | 71,122,478 | 13 | 31 | 15 | 0.2% |
| Q4 2022 | 76 | $478.4M | 68,142,673 | 20 | 20 | 21 | 0.3% |
| Q3 2022 | 60 | $243.1M | 67,256,310 | 9 | 18 | 14 | 0.1% |
| Q2 2022 | 60 | $220.4M | 67,764,215 | 12 | 10 | 28 | 0.1% |
| Q1 2022 | 80 | $95.9M | 47,858,037 | 6 | 22 | 30 | 0.1% |
| Q4 2021 | 89 | $149.1M | 47,356,722 | 16 | 38 | 18 | 0.3% |
| Q3 2021 | 85 | $184.4M | 37,421,220 | 14 | 22 | 26 | 0.5% |
| Q2 2021 | 85 | $249.0M | 37,040,018 | 14 | 28 | 27 | 0.9% |
| Q1 2021 | 97 | $227.4M | 38,266,119 | 16 | 28 | 32 | 5.6% |
| Q4 2020 | 103 | $374.3M | 47,135,223 | 20 | 34 | 29 | 0.9% |
| Q3 2020 | 106 | $388.0M | 44,773,807 | 27 | 40 | 29 | 1.8% |
| Q2 2020 | 91 | $387.7M | 36,964,488 | 23 | 27 | 25 | 0.8% |
| Q1 2020 | 78 | $458.0M | 48,378,593 | 12 | 26 | 25 | 1.0% |
| Q4 2019 | 95 | $729.1M | 88,871,333 | 18 | 32 | 27 | 2.2% |
| Q3 2019 | 87 | $800.1M | 38,713,112 | 7 | 30 | 32 | 0.7% |
| Q2 2019 | 102 | $964.6M | 36,534,933 | 25 | 48 | 16 | 1.2% |
| Q1 2019 | 112 | $1.4B | 35,571,601 | 34 | 53 | 16 | 1.0% |
| Q4 2018 | 90 | $1.0B | 24,448,547 | 1 | 0 | 4 | 0.0% |