DaveManuel.com · Institutional Ownership · Who Owns It
XERIS BIOPHARMA HOLDINGS INC (XERS)
Institutional ownership reported to the SEC as of Q2 2026, across 32 quarters.
243
Reporting holders
$871.0M
Reported value
59.4%
Of shares outstanding
1.0%
Calls
0.5%
Puts
+7
Holder change
Institutions report 108,331,752 shares against 182,320,306 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| BlackRock, Inc. | $115.0M | 14,525,539 | 0.00% | 8q | +12.2%+$12.5M |
| D. E. Shaw & Co., Inc. | $61.8M | 7,804,758 | 0.03% | 18q | HELD |
| VANGUARD CAPITAL MANAGEMENT LLC | $58.1M | 7,340,229 | 0.00% | 2q | +5.1%+$2.8M |
| STATE STREET CORP | $38.2M | 4,821,566 | 0.00% | 19q | +3.5%+$1.3M |
| GEODE CAPITAL MANAGEMENT, LLC | $37.4M | 4,718,183 | 0.00% | 20q | +10.0%+$3.4M |
| Nuveen, LLC | $34.7M | 4,385,141 | 0.01% | 6q | +50.4%+$11.6M |
| Rosalind Advisors, Inc. | $23.0M | 2,908,981 | 8.56% | 11q | -10.0%-$2.6M |
| Qube Research & Technologies Ltd | $22.9M | 2,893,749 | 0.02% | 10q | -29.7%-$9.7M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $20.8M | 2,626,208 | 0.00% | 2q | -1.5%-$312.0K |
| WELLINGTON MANAGEMENT GROUP LLP | $18.7M | 2,365,103 | 0.00% | 10q | +8.9%+$1.5M |
| MORGAN STANLEY | $18.5M | 2,337,096 | 0.00% | 19q | -9.2%-$1.9M |
| Legal & General Group Plc | $15.9M | 2,012,792 | 0.00% | 17q | +5.5%+$827.7K |
| ARMISTICE CAPITAL, LLC | $15.5M | 1,958,702 | 0.19% | 2q | +2.6%+$387.0K |
| TWO SIGMA INVESTMENTS, LP | $14.9M | 1,885,503 | 0.01% | 6q | -2.0%-$306.5K |
| Parkman Healthcare Partners LLC | $14.3M | 1,807,621 | 1.47% | 10q | +5.0%+$683.9K |
| ALGERT GLOBAL LLC | $13.8M | 1,742,942 | 0.16% | 4q | +50.6%+$4.6M |
| NORTHERN TRUST CORP | $12.7M | 1,597,749 | 0.00% | 19q | +10.6%+$1.2M |
| GOLDMAN SACHS GROUP INC | $12.6M | 1,594,072 | 0.00% | 19q | -1.2%-$155.1K |
| AQR CAPITAL MANAGEMENT LLC | $12.2M | 1,540,985 | 0.00% | 16q | +10.5%+$1.2M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $11.8M | 1,492,367 | 0.00% | 19q | +9.8%+$1.1M |
| FEDERATED HERMES, INC. | $11.4M | 1,434,433 | 0.02% | 8q | +67.4%+$4.6M |
| BANK OF AMERICA CORP /DE/ | $11.1M | 1,397,050 | 0.00% | 19q | +59.8%+$4.1M |
| UBS Group AG | $10.3M | 1,300,913 | 0.00% | 19q | -21.0%-$2.7M |
| Ishara Investments LP | $9.7M | 1,230,000 | 7.16% | 3q | +20.0%+$1.6M |
| VANGUARD FIDUCIARY TRUST CO | $9.7M | 1,224,398 | 0.00% | 2q | +8.0%+$716.7K |
| KENNEDY CAPITAL MANAGEMENT LLC | $9.6M | 1,209,068 | 0.17% | 8q | -2.5%-$250.5K |
| DIMENSIONAL FUND ADVISORS LP | $8.5M | 1,073,639 | 0.00% | new | NEW |
| Knott David M Jr | $8.4M | 1,060,000 | 4.44% | 11q | HELD |
| JPMORGAN CHASE & CO | $8.2M | 1,058,067 | 0.00% | 19q | +72.8%+$3.4M |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $7.7M | 972,880 | 0.00% | 3q | +627.3%+$6.6M |
| Caption Management, LLC | $7.3M incl. $5.7M options CALL+PUT | 197,863 | 0.03% | 3q | -3.5%-$263.2K |
| Granahan Investment Management, LLC | $7.1M | 898,753 | 0.25% | 4q | -2.5%-$183.0K |
| NORGES BANK | $6.3M | 797,200 | 0.00% | 4q | HELD |
| CITADEL ADVISORS LLC | $6.1M incl. $855.4K options CALL+PUT | 664,564 | 0.00% | 19q | -2.5%-$157.2K |
| ESSEX INVESTMENT MANAGEMENT CO LLC | $5.7M | 715,608 | 0.74% | 7q | -4.3%-$254.7K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $5.4M | 687,632 | 0.00% | 5q | +2.9%+$154.9K |
| VOYA INVESTMENT MANAGEMENT LLC | $5.4M | 685,570 | 0.00% | 17q | +9.6%+$477.3K |
| FMR LLC | $5.1M | 644,057 | 0.00% | 18q | +25.5%+$1.0M |
| Walleye Capital LLC | $4.8M | 611,296 | 0.02% | new | NEW |
| DEUTSCHE BANK AG\ | $4.2M | 529,443 | 0.00% | 17q | -15.0%-$741.1K |
| Bank of New York Mellon Corp | $3.9M | 488,441 | 0.00% | 19q | +14.6%+$492.3K |
| FIRST TRUST ADVISORS LP | $3.8M | 484,978 | 0.00% | new | NEW |
| IHT Wealth Management, LLC | $3.8M | 481,871 | 0.08% | 17q | +28.0%+$834.7K |
| PERCEPTIVE ADVISORS LLC | $3.7M | 467,013 | 0.06% | new | NEW |
| ROYCE & ASSOCIATES LP | $3.7M | 461,153 | 0.03% | 2q | +80.1%+$1.6M |
| Man Group plc | $3.6M | 455,380 | 0.01% | 3q | +64.7%+$1.4M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $3.6M incl. $2.5M options CALL+PUT | 139,918 | 0.00% | 19q | -51.1%-$3.8M |
| Russell Investments Group, Ltd. | $3.5M | 440,731 | 0.00% | 10q | +14.7%+$447.8K |
| BNP PARIBAS FINANCIAL MARKETS | $3.4M | 430,488 | 0.00% | 7q | +63.8%+$1.3M |
| STATE OF WISCONSIN INVESTMENT BOARD | $3.4M | 427,513 | 0.01% | 6q | +38.6%+$942.2K |
| Jupiter Topco LLC | $3.3M | 414,959 | 0.00% | new | FIRST |
| Y-Intercept (Hong Kong) Ltd | $3.3M | 411,346 | 0.06% | 6q | +154.2%+$2.0M |
| Squarepoint Ops LLC | $2.9M | 365,731 | 0.00% | 8q | -40.5%-$2.0M |
| HRT FINANCIAL LP | $2.9M | 365,659 | 0.01% | 4q | +113.7%+$1.5M |
| SEI INVESTMENTS CO | $2.7M | 339,509 | 0.00% | 6q | -41.4%-$1.9M |
| Trexquant Investment LP | $2.7M | 339,113 | 0.02% | 4q | -59.3%-$3.9M |
| Swiss National Bank | $2.7M | 337,500 | 0.00% | 4q | +2.8%+$72.9K |
| Schonfeld Strategic Advisors LLC | $2.5M | 318,177 | 0.01% | 10q | +7.3%+$172.2K |
| RICE HALL JAMES & ASSOCIATES, LLC | $2.4M | 300,791 | 0.12% | 2q | +19.8%+$393.8K |
| Jefferies Financial Group Inc. | $2.3M | 293,670 | 0.02% | 3q | +234.5%+$1.6M |
| CenterBook Partners LP | $2.2M | 280,565 | 0.11% | 11q | -77.5%-$7.7M |
| PRICE T ROWE ASSOCIATES INC /MD/ | $2.1M | 266,877 | 0.00% | 19q | +27.7%+$458.2K |
| Stonepine Capital Management, LLC | $2.1M CALL | options only | 1.18% | 2q | OPTIONS |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | $2.1M | 263,537 | 0.00% | 6q | -43.2%-$1.6M |
| Cliffwater LLC | $2.1M | 263,158 | 0.52% | new | NEW |
| GROUP ONE TRADING LLC | $2.0M incl. $247.9K options CALL+PUT | 226,607 | 0.00% | 4q | +3.9%+$76.3K |
| Apella Capital, LLC | $1.9M | 215,897 | 0.03% | 6q | -8.5%-$178.8K |
| Legato Capital Management LLC | $1.9M | 241,341 | 0.16% | 7q | +3.1%+$57.0K |
| PANAGORA ASSET MANAGEMENT INC | $1.8M | 227,579 | 0.01% | 2q | +117.3%+$972.9K |
| PRINCIPAL FINANCIAL GROUP INC | $1.8M | 227,418 | 0.00% | 17q | +9.1%+$149.8K |
| CANADA PENSION PLAN INVESTMENT BOARD | $1.7M | 219,200 | 0.00% | 4q | -41.5%-$1.2M |
| RHUMBLINE ADVISERS | $1.7M | 214,205 | 0.00% | 17q | +12.1%+$183.3K |
| COMMONWEALTH EQUITY SERVICES, LLC | $1.6M | 205,855 | 0.00% | 19q | +1.3%+$21.7K |
| Voleon Capital Management LP | $1.6M | 204,732 | 0.03% | 2q | +340.2%+$1.3M |
| RAYMOND JAMES FINANCIAL INC | $1.6M | 202,911 | 0.00% | 7q | -2.6%-$42.5K |
| Aquatic Capital Management LLC | $1.6M | 199,983 | 0.05% | new | NEW |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $1.5M | 186,800 | 0.00% | 17q | +3.6%+$51.2K |
| Corient Private Wealth LP | $1.5M | 184,126 | 0.00% | new | NEW |
| Virtus Investment Advisers, LLC | $1.4M | 171,264 | 0.32% | 6q | +350.3%+$1.1M |
| BARCLAYS PLC | $1.3M | 166,566 | 0.00% | 18q | +20.2%+$221.9K |
| SIMPLEX TRADING, LLC | $1.3M CALL+PUT | options only | 0.00% | 2q | OPTIONS |
| WELLS FARGO & COMPANY/MN | $1.2M | 157,487 | 0.00% | 19q | +170.1%+$785.5K |
| Creative Planning | $1.2M | 154,059 | 0.00% | 10q | +15.6%+$164.5K |
| Quarry LP | $1.2M | 150,057 | 0.10% | 6q | +20.0%+$198.5K |
| GLOBEFLEX CAPITAL L P | $1.2M | 145,917 | 0.15% | 7q | +18.5%+$180.0K |
| AMERIPRISE FINANCIAL INC | $1.1M | 143,285 | 0.00% | 19q | +0.8%+$9.0K |
| CITIGROUP INC | $1.1M | 134,298 | 0.00% | 19q | +53.8%+$372.0K |
| VANGUARD ASSET MANAGEMENT, Ltd | $1.1M | 133,417 | 0.00% | 2q | +28.8%+$236.5K |
| DIADEMA PARTNERS LP | $1.1M | 132,746 | 0.13% | 4q | HELD |
| MILLENNIUM MANAGEMENT LLC | $1.0M | 131,664 | 0.00% | 13q | -94.2%-$16.9M |
| LPL Financial LLC | $1.0M | 128,941 | 0.00% | 11q | +37.4%+$277.8K |
| Connor, Clark & Lunn Investment Management Ltd. | $1.0M | 127,107 | 0.00% | 8q | -68.8%-$2.2M |
| Gotham Asset Management, LLC | $981.4K | 123,914 | 0.00% | 6q | +186.5%+$638.8K |
| Quantbot Technologies LP | $879.9K | 111,102 | 0.03% | 6q | +295.9%+$657.7K |
| Invesco Ltd. | $870.2K | 109,875 | 0.00% | 19q | +6.4%+$52.1K |
| ALLIANCEBERNSTEIN L.P. | $842.9K | 145,336 | 0.00% | 17q | HELD |
| Palo Alto Investors LP | $826.9K | 104,410 | 0.11% | 2q | HELD |
| MetLife Investment Management, LLC | $793.3K | 100,167 | 0.00% | 2q | +30.5%+$185.4K |
| Palogic Value Management, L.P. | $793.1K | 100,136 | 0.13% | 2q | +100.3%+$397.1K |
| IEQ CAPITAL, LLC | $779.6K | 98,429 | 0.00% | 19q | +20.6%+$133.0K |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-10-30 | 13G/A | Vanguard Capital Management | 5.0% |
What the insiders did
Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.
Officers and directors
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-07-01 | McCulloch Kevin | See Remarks | Sold | 90,000 | $722.5K |
| 2026-09-28 | McCulloch Kevin | See Remarks | Sold | 25,000 | $250.0K |
| 2026-07-07 | Pieper Steven | See Remarks | Sold | 27,600 | $235.3K |
| 2026-10-01 | Hecht Beth | See Remarks | Sold | 16,666 | $156.8K |
| 2026-07-06 | Pieper Steven | See Remarks | Sold | 17,400 | $147.9K |
| 2026-09-01 | Hecht Beth | See Remarks | Sold | 16,666 | $141.4K |
| 2026-10-01 | McCulloch Kevin | See Remarks | Sold | 15,000 | $141.1K |
| 2026-07-01 | Hecht Beth | See Remarks | Sold | 16,666 | $133.9K |
| 2026-08-03 | Hecht Beth | See Remarks | Sold | 16,666 | $133.6K |
| 2026-09-01 | McCulloch Kevin | See Remarks | Sold | 15,000 | $127.3K |
| 2026-06-04 | HALKUFF DAWN | Director | Sold | 20,000 | $121.9K |
| 2026-08-03 | McCulloch Kevin | See Remarks | Sold | 15,000 | $120.2K |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 40 | $26.4M | 2,746,537 | 6 | 17 | 8 | 0.0% |
| Q2 2026 | 243 | $871.0M | 108,331,752 | 34 | 102 | 66 | 1.5% |
| Q1 2026 | 236 | $619.7M | 105,202,228 | 42 | 95 | 54 | 1.4% |
| Q4 2025 | 228 | $796.7M | 100,822,831 | 33 | 76 | 70 | 0.7% |
| Q3 2025 | 231 | $800.6M | 97,781,946 | 58 | 73 | 59 | 0.6% |
| Q2 2025 | 202 | $424.1M | 90,514,157 | 23 | 73 | 61 | 0.3% |
| Q1 2025 | 202 | $484.1M | 87,637,248 | 56 | 69 | 37 | 0.6% |
| Q4 2024 | 164 | $224.5M | 65,978,394 | 21 | 59 | 31 | 0.5% |
| Q3 2024 | 147 | $184.9M | 64,310,473 | 24 | 45 | 33 | 0.9% |
| Q2 2024 | 138 | $138.5M | 61,058,921 | 13 | 51 | 36 | 0.8% |
| Q1 2024 | 145 | $142.3M | 63,871,952 | 37 | 47 | 29 | 0.8% |
| Q4 2023 | 121 | $147.2M | 61,736,361 | 19 | 35 | 29 | 1.5% |
| Q3 2023 | 112 | $104.8M | 55,320,276 | 16 | 33 | 25 | 1.8% |
| Q2 2023 | 105 | $149.8M | 56,146,387 | 21 | 27 | 26 | 1.8% |
| Q1 2023 | 94 | $81.4M | 49,473,273 | 10 | 25 | 24 | 0.9% |
| Q4 2022 | 96 | $73.6M | 53,865,355 | 9 | 24 | 26 | 2.7% |
| Q3 2022 | 100 | $94.3M | 58,890,238 | 10 | 28 | 26 | 2.5% |
| Q2 2022 | 100 | $106.8M | 67,383,905 | 25 | 26 | 25 | 2.8% |
| Q1 2022 | 103 | $134.6M | 50,793,011 | 28 | 28 | 25 | 3.4% |
| Q4 2021 | 93 | $193.3M | 62,855,345 | 92 | 1 | 0 | 4.7% |
| Q3 2021 | 68 | $49.5M | 17,511,152 | 8 | 23 | 20 | 13.2% |
| Q2 2021 | 93 | $126.1M | 28,218,355 | 25 | 21 | 33 | 8.9% |
| Q1 2021 | 101 | $161.3M | 33,185,161 | 17 | 37 | 24 | 7.2% |
| Q4 2020 | 97 | $142.9M | 25,784,103 | 20 | 36 | 22 | 11.1% |
| Q3 2020 | 88 | $335.4M | 54,274,367 | 30 | 25 | 23 | 4.1% |
| Q2 2020 | 83 | $86.0M | 32,073,774 | 28 | 35 | 13 | 0.8% |
| Q1 2020 | 65 | $45.8M | 23,473,984 | 21 | 21 | 14 | 0.1% |
| Q4 2019 | 55 | $130.6M | 17,983,921 | 11 | 23 | 10 | 0.2% |
| Q3 2019 | 51 | $275.7M | 28,044,829 | 7 | 26 | 9 | 0.0% |
| Q2 2019 | 48 | $218.1M | 19,070,034 | 12 | 21 | 7 | 0.0% |
| Q1 2019 | 48 | $161.0M | 16,037,055 | 17 | 23 | 2 | 0.0% |
| Q4 2018 | 35 | $184.9M | 10,877,641 | 0 | 0 | 2 | 0.0% |