ALTO NEUROSCIENCE INC (ANRO)
Institutional ownership reported to the SEC as of Q2 2026, across 11 quarters.
Institutions report 29,470,567 shares against 39,242,104 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| Alpha Wave Global, LP | $97.8M | 3,707,757 | 1.57% | 10q | HELD |
| Commodore Capital LP | $71.9M | 2,723,196 | 4.28% | 3q | HELD |
| BlackRock, Inc. | $56.0M | 2,121,009 | 0.00% | 8q | +218.4%+$38.4M |
| PERCEPTIVE ADVISORS LLC | $42.5M | 1,609,893 | 0.64% | 4q | -19.9%-$10.6M |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $42.2M | 1,600,000 | 0.06% | 2q | +315.6%+$32.1M |
| VANGUARD CAPITAL MANAGEMENT LLC | $36.7M | 1,389,477 | 0.00% | 2q | +15.1%+$4.8M |
| Spruce Street Capital LP | $35.7M | 1,353,047 | 7.01% | 3q | +2.1%+$734.6K |
| Vivo Capital, LLC | $31.9M | 1,208,858 | 2.91% | 3q | +16.7%+$4.6M |
| FRANKLIN RESOURCES INC | $26.7M | 1,013,307 | 0.01% | 10q | -8.0%-$2.3M |
| ARMISTICE CAPITAL, LLC | $22.8M | 864,000 | 0.28% | 7q | -5.3%-$1.3M |
| Affinity Asset Advisors, LLC | $22.4M | 850,000 | 1.01% | 2q | +70.0%+$9.2M |
| Vestal Point Capital, LP | $20.7M | 785,000 | 0.48% | 10q | -62.0%-$33.8M |
| STATE STREET CORP | $18.1M | 685,945 | 0.00% | 10q | +243.8%+$12.8M |
| GEODE CAPITAL MANAGEMENT, LLC | $17.9M | 678,199 | 0.00% | 10q | +131.5%+$10.2M |
| 72 Investment Holdings, LLC | $17.6M | 667,778 | 35.27% | 10q | HELD |
| NORTHERN TRUST CORP | $16.7M | 632,701 | 0.00% | 10q | +33.6%+$4.2M |
| MILLENNIUM MANAGEMENT LLC | $14.7M | 558,320 | 0.01% | 6q | -32.1%-$7.0M |
| Point72 Asset Management, L.P. | $13.3M | 502,950 | 0.01% | 10q | HELD |
| Venrock Adviser, LLC | $13.2M | 500,000 | 0.40% | 2q | HELD |
| Integral Health Asset Management, LLC | $13.2M | 500,000 | 0.52% | 7q | HELD |
| Driehaus Capital Management LLC | $12.9M | 487,576 | 0.07% | 3q | HELD |
| Parkman Healthcare Partners LLC | $11.3M | 429,035 | 1.16% | new | NEW |
| Ikarian Capital, LLC | $10.7M | 407,338 | 1.16% | 8q | -20.9%-$2.8M |
| PRICE T ROWE ASSOCIATES INC /MD/ | $9.5M | 358,279 | 0.00% | 10q | -3.5%-$341.2K |
| ORBIMED ADVISORS LLC | $6.8M | 257,852 | 0.13% | 7q | +53.9%+$2.4M |
| Schonfeld Strategic Advisors LLC | $6.8M | 257,631 | 0.02% | new | NEW |
| GOLDMAN SACHS GROUP INC | $6.2M | 236,830 | 0.00% | 9q | +126.2%+$3.5M |
| MARSHALL WACE, LLP | $6.0M | 225,503 | 0.00% | 7q | +27.9%+$1.3M |
| VANGUARD FIDUCIARY TRUST CO | $5.6M | 211,257 | 0.00% | 2q | +27.8%+$1.2M |
| AMERIPRISE FINANCIAL INC | $5.0M | 190,996 | 0.00% | 8q | +1333.5%+$4.7M |
| Saturn V Capital Management LP | $4.8M | 182,829 | 0.69% | 2q | +105.4%+$2.5M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $4.8M | 181,101 | 0.00% | new | NEW |
| TWO SIGMA INVESTMENTS, LP | $3.9M | 147,299 | 0.00% | 8q | -31.8%-$1.8M |
| Eversept Partners, LP | $3.4M | 128,286 | 0.18% | 2q | +2.5%+$82.3K |
| BOOTHBAY FUND MANAGEMENT, LLC | $2.8M | 106,234 | 0.04% | 8q | -23.7%-$872.7K |
| ALKEON CAPITAL MANAGEMENT LLC | $2.7M | 102,101 | 0.00% | 9q | -55.0%-$3.3M |
| STIFEL FINANCIAL CORP | $2.3M | 85,480 | 0.00% | 7q | -1.0%-$22.6K |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $2.1M | 80,583 | 0.00% | 3q | +373.5%+$1.7M |
| AWM Investment Company, Inc. | $2.1M | 80,000 | 0.18% | 10q | -52.9%-$2.4M |
| Bank of New York Mellon Corp | $2.0M | 76,330 | 0.00% | new | NEW |
| MORGAN STANLEY | $2.0M | 74,940 | 0.00% | 10q | +9.2%+$165.9K |
| RENAISSANCE TECHNOLOGIES LLC | $1.9M | 71,399 | 0.00% | 5q | -31.0%-$847.1K |
| WELLINGTON MANAGEMENT GROUP LLP | $1.9M | 70,913 | 0.00% | 3q | +18.6%+$293.3K |
| AdvisorShares Investments LLC | $1.9M | 70,748 | 0.23% | 3q | +72.5%+$784.4K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1.8M incl. $1.6M options CALL+PUT | 7,998 | 0.00% | 8q | -96.6%-$52.7M |
| Nuveen, LLC | $1.6M | 62,342 | 0.00% | new | NEW |
| UBS Group AG | $1.5M | 58,697 | 0.00% | 10q | +240.3%+$1.1M |
| ACADIAN ASSET MANAGEMENT LLC | $1.5M | 55,509 | 0.00% | 5q | -7.6%-$120.5K |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $1.3M | 50,653 | 0.02% | 6q | -3.8%-$52.8K |
| XTX Topco Ltd | $1.2M | 46,601 | 0.02% | 4q | +17.0%+$178.4K |
| TD Asset Management Inc | $1.2M | 43,800 | 0.00% | 2q | HELD |
| DIMENSIONAL FUND ADVISORS LP | $1.1M | 42,561 | 0.00% | 3q | +8.2%+$85.4K |
| Quantinno Capital Management LP | $1.0M | 38,556 | 0.00% | 5q | +6.9%+$65.6K |
| ALPS ADVISORS INC | $939.8K | 35,613 | 0.00% | 3q | +40.8%+$272.5K |
| RHUMBLINE ADVISERS | $834.9K | 31,636 | 0.00% | new | NEW |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $797.8K | 30,233 | 0.00% | 2q | +27.3%+$171.2K |
| AMERICAN CENTURY COMPANIES INC | $707.8K | 26,820 | 0.00% | 3q | +89.1%+$333.4K |
| WELLS FARGO & COMPANY/MN | $694.1K | 26,303 | 0.00% | 3q | +3229.5%+$673.3K |
| DEUTSCHE BANK AG\ | $687.5K | 26,051 | 0.00% | new | NEW |
| Allianz Asset Management GmbH | $686.1K | 26,000 | 0.00% | 8q | -8.8%-$66.0K |
| BROWN ADVISORY INC | $659.8K | 25,000 | 0.00% | 7q | HELD |
| JANE STREET GROUP, LLC | $622.8K CALL | options only | 0.00% | 5q | OPTIONS |
| ALLIANCEBERNSTEIN L.P. | $613.7K | 27,300 | 0.00% | new | NEW |
| UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO | $585.2K | 22,175 | 0.07% | 10q | HELD |
| Squarepoint Ops LLC | $561.7K | 21,286 | 0.00% | 2q | -29.0%-$228.9K |
| CITIGROUP INC | $547.5K | 20,745 | 0.00% | 3q | +120.0%+$298.6K |
| BANK OF AMERICA CORP /DE/ | $504.1K | 19,101 | 0.00% | 10q | -25.6%-$173.5K |
| Revisor Wealth Management LLC | $452.1K | 17,130 | 0.11% | 2q | HELD |
| SCS Capital Management LLC | $444.4K | 16,840 | 0.00% | 6q | HELD |
| MetLife Investment Management, LLC | $412.8K | 15,644 | 0.00% | new | NEW |
| Virtus Investment Advisers, LLC | $402.2K | 15,239 | 0.09% | new | NEW |
| CITADEL ADVISORS LLC | $398.5K CALL | options only | 0.00% | 8q | OPTIONS |
| BANK OF NOVA SCOTIA | $380.0K | 14,400 | 0.00% | new | NEW |
| Invesco Ltd. | $376.2K | 14,255 | 0.00% | new | NEW |
| BARCLAYS PLC | $351.5K | 13,318 | 0.00% | 10q | -46.8%-$309.2K |
| Vanguard Personalized Indexing Management, LLC | $334.0K | 12,658 | 0.00% | 5q | -19.1%-$78.9K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $316.9K | 12,009 | 0.00% | new | NEW |
| JPMORGAN CHASE & CO | $306.1K | 10,904 | 0.00% | 3q | +23604.3%+$304.8K |
| BANK OF MONTREAL /CAN/ | $301.2K | 11,415 | 0.00% | 5q | +0.6%+$1.9K |
| Vanguard Global Advisers, LLC | $281.0K | 10,649 | 0.00% | 2q | HELD |
| NEW YORK STATE COMMON RETIREMENT FUND | $242.8K | 9,200 | 0.00% | new | NEW |
| GK Wealth Management LLC | $226.0K | 8,565 | 0.12% | new | NEW |
| IEQ CAPITAL, LLC | $210.8K | 7,988 | 0.00% | 8q | -66.3%-$415.4K |
| PROFUND ADVISORS LLC | $208.7K | 7,908 | 0.01% | new | NEW |
| Police & Firemen's Retirement System of New Jersey | $203.9K | 7,725 | 0.00% | new | NEW |
| Persistent Asset Partners Ltd | $203.2K | 7,698 | 0.06% | new | NEW |
| State of Wyoming | $202.8K | 7,684 | 0.02% | new | NEW |
| FMR LLC | $166.9K | 6,325 | 0.00% | 10q | HELD |
| SIMPLEX TRADING, LLC | $113.5K CALL+PUT | options only | 0.00% | new | OPTIONS |
| BNP PARIBAS FINANCIAL MARKETS | $102.4K | 3,880 | 0.00% | 9q | +1135.7%+$94.1K |
| ROYAL BANK OF CANADA | $95.0K | 3,575 | 0.00% | 9q | +8619.5%+$93.9K |
| Legal & General Group Plc | $67.1K | 2,543 | 0.00% | new | NEW |
| WHITTIER TRUST CO OF NEVADA INC | $63.8K | 2,482 | 0.00% | 7q | HELD |
| Russell Investments Group, Ltd. | $63.3K | 2,400 | 0.00% | 5q | +684.3%+$55.3K |
| Ameritas Investment Partners, Inc. | $62.7K | 2,377 | 0.00% | new | NEW |
| Tower Research Capital LLC (TRC) | $52.7K | 1,996 | 0.00% | 8q | +2970.8%+$51.0K |
| GROUP ONE TRADING LLC | $42.2K CALL+PUT | options only | 0.00% | new | OPTIONS |
| PNC Financial Services Group, Inc. | $31.7K | 1,200 | 0.00% | 6q | HELD |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $26.5K | 1,006 | 0.00% | new | NEW |
| ROTHSCHILD INVESTMENT LLC | $18.1K | 685 | 0.00% | 8q | -59.3%-$26.4K |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-10-30 | 13G | Vanguard Capital Management | 5.0% |
What the company announced
Form 8-K filings from the last 120 days, showing only the items worth a reader's attention. Earnings releases, exhibit attachments and general disclosures are filed constantly and are left out. Filed is when the SEC received it; event is the date the company says the thing happened.
| Filed | Event date | What | Source |
|---|---|---|---|
| 2026-08-27 | 2026-08-26 | Directors or officers departed or appointed | filing |
What the insiders did
Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.
Officers and directors
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-09-29 | Smith Nicholas Conrad | PRESIDENT AND CFO | Sold | 110,830 | $2.9M |
| 2026-09-30 | Smith Nicholas Conrad | PRESIDENT AND CFO | Sold | 24,056 | $621.1K ×2 |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 16 | $1.7M | 66,912 | 6 | 6 | 4 | 0.0% |
| Q2 2026 | 118 | $780.4M | 29,470,567 | 29 | 37 | 27 | 0.4% |
| Q1 2026 | 111 | $613.2M | 26,830,701 | 22 | 27 | 41 | 1.8% |
| Q4 2025 | 98 | $443.9M | 24,487,036 | 26 | 26 | 25 | 1.8% |
| Q3 2025 | 77 | $68.3M | 16,952,879 | 8 | 18 | 25 | 0.2% |
| Q2 2025 | 82 | $38.1M | 17,308,113 | 18 | 21 | 24 | 0.1% |
| Q1 2025 | 83 | $45.1M | 20,845,367 | 19 | 17 | 26 | 0.3% |
| Q4 2024 | 79 | $95.7M | 22,530,140 | 21 | 31 | 10 | 0.4% |
| Q3 2024 | 83 | $283.3M | 22,963,889 | 28 | 35 | 9 | 6.2% |
| Q2 2024 | 58 | $198.9M | 18,604,453 | 17 | 19 | 11 | 0.0% |
| Q1 2024 | 52 | $246.3M | 16,045,554 | 52 | 0 | 0 | 0.0% |