DaveManuel.com · Institutional Ownership · Who Owns It
ARROWHEAD PHARMACEUTICALS IN (ARWR)
Institutional ownership reported to the SEC as of Q2 2026, across 32 quarters.
512
Reporting holders
$10.0B
Reported value
84.8%
Of shares outstanding
1.6%
Calls
0.6%
Puts
+66
Holder change
Institutions report 119,719,661 shares against 141,254,467 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| BlackRock, Inc. | $1.2B | 14,830,553 | 0.02% | 8q | -18.3%-$271.5M |
| Avoro Capital Advisors LLC | $925.6M | 11,355,555 | 8.31% | 13q | +6.1%+$53.4M |
| FMR LLC | $655.3M | 8,039,804 | 0.03% | 31q | +10.6%+$63.0M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $517.7M | 6,351,355 | 0.02% | 2q | -11.1%-$64.8M |
| VANGUARD CAPITAL MANAGEMENT LLC | $498.1M | 6,110,953 | 0.01% | 2q | +1.3%+$6.4M |
| STATE STREET CORP | $464.2M | 5,694,640 | 0.01% | 31q | -12.3%-$65.3M |
| NORGES BANK | $317.6M | 3,896,536 | 0.03% | 26q | +128.6%+$178.7M |
| Invesco Ltd. | $316.6M | 3,883,976 | 0.03% | 31q | +18.4%+$49.2M |
| GEODE CAPITAL MANAGEMENT, LLC | $298.8M | 3,530,612 | 0.02% | 31q | -17.5%-$63.3M |
| FRED ALGER MANAGEMENT, LLC | $269.1M | 3,301,919 | 0.90% | 4q | -1.2%-$3.3M |
| BAKER BROS. ADVISORS LP | $162.4M | 1,992,783 | 0.81% | 5q | HELD |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $153.9M incl. $105.3M options CALL+PUT | 596,573 | 0.01% | 31q | +57.5%+$56.2M |
| Siren, L.L.C. | $139.8M | 1,715,476 | 2.83% | 8q | +6.2%+$8.2M |
| Vestal Point Capital, LP | $128.4M | 1,575,000 | 3.00% | 3q | -30.8%-$57.1M |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $113.2M | 1,389,055 | 1.18% | 4q | -11.7%-$15.0M |
| FIRST TRUST ADVISORS LP | $110.3M | 1,352,918 | 0.06% | 4q | +807.1%+$98.1M |
| Driehaus Capital Management LLC | $110.1M | 1,350,556 | 0.64% | 4q | +13.5%+$13.1M |
| Jupiter Topco LLC | $99.6M | 1,221,596 | 0.04% | new | FIRST |
| NORTHERN TRUST CORP | $97.2M | 1,192,868 | 0.01% | 31q | -28.0%-$37.7M |
| DIMENSIONAL FUND ADVISORS LP | $96.3M | 1,181,608 | 0.02% | 5q | +94.2%+$46.7M |
| GOLDMAN SACHS GROUP INC | $93.7M | 1,150,007 | 0.01% | 31q | -33.9%-$48.1M |
| BANK OF AMERICA CORP /DE/ | $92.9M | 1,139,810 | 0.01% | 31q | +7.1%+$6.1M |
| Hood River Capital Management LLC | $91.4M | 1,120,747 | 0.66% | 2q | +6.1%+$5.2M |
| Holocene Advisors, LP | $90.2M | 1,106,177 | 0.20% | new | NEW |
| MORGAN STANLEY | $88.4M | 1,084,835 | 0.00% | 35q | +12.9%+$10.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $78.6M | 964,479 | 0.01% | 31q | -27.5%-$29.9M |
| Fisher Asset Management, LLC | $78.1M | 957,691 | 0.02% | 9q | -14.0%-$12.7M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $75.3M | 923,927 | 0.01% | 31q | -22.5%-$21.9M |
| VANGUARD FIDUCIARY TRUST CO | $73.1M | 896,738 | 0.02% | 2q | -7.1%-$5.6M |
| UBS Group AG | $70.2M | 861,520 | 0.01% | 31q | -35.5%-$38.7M |
| Bank of New York Mellon Corp | $70.1M | 859,538 | 0.01% | 31q | -10.5%-$8.2M |
| PRICE T ROWE ASSOCIATES INC /MD/ | $69.6M | 853,360 | 0.01% | 31q | -18.2%-$15.5M |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | $67.7M | 830,247 | 1.19% | 3q | +53.7%+$23.6M |
| Western Financial Corp/CA | $66.9M | 820,239 | 19.58% | 15q | HELD |
| JPMORGAN CHASE & CO | $51.8M | 637,399 | 0.00% | 31q | -6.7%-$3.7M |
| Connor, Clark & Lunn Investment Management Ltd. | $51.0M | 625,569 | 0.10% | 4q | -25.3%-$17.2M |
| TWO SIGMA INVESTMENTS, LP | $47.3M | 580,609 | 0.03% | 2q | +1521.8%+$44.4M |
| Pictet Asset Management Holding SA | $46.7M | 573,419 | 0.04% | 12q | -55.0%-$57.0M |
| BNP PARIBAS FINANCIAL MARKETS | $45.5M | 558,643 | 0.02% | 30q | -14.1%-$7.5M |
| LORD, ABBETT & CO. LLC | $44.1M | 540,466 | 0.13% | 2q | +72.8%+$18.6M |
| 1832 Asset Management L.P. | $43.9M | 538,500 | 0.02% | new | NEW |
| HRT FINANCIAL LP | $43.1M incl. $2.5M options OPT | 529,055 | 0.08% | new | NEW |
| PRINCIPAL FINANCIAL GROUP INC | $41.9M | 514,658 | 0.02% | 31q | +5.0%+$2.0M |
| VOYA INVESTMENT MANAGEMENT LLC | $39.4M | 483,495 | 0.03% | 31q | -26.3%-$14.1M |
| Balyasny Asset Management L.P. | $38.4M | 470,754 | 0.05% | 4q | +128.1%+$21.5M |
| RENAISSANCE TECHNOLOGIES LLC | $38.2M | 468,921 | 0.05% | 2q | -54.8%-$46.3M |
| FRANKLIN RESOURCES INC | $37.7M | 462,133 | 0.01% | 5q | HELD |
| JANE STREET GROUP, LLC | $35.3M incl. $19.3M options CALL+PUT | 196,205 | 0.00% | 28q | +1143.8%+$32.5M |
| D. E. Shaw & Co., Inc. | $35.2M | 431,560 | 0.02% | 6q | -63.5%-$61.3M |
| Nuveen, LLC | $33.9M | 415,883 | 0.01% | 6q | -16.8%-$6.8M |
| MILLENNIUM MANAGEMENT LLC | $33.2M incl. $6.4M options CALL | 329,337 | 0.01% | new | NEW |
| Assenagon Asset Management S.A. | $32.9M | 403,854 | 0.02% | 14q | +587.6%+$28.1M |
| RHUMBLINE ADVISERS | $30.6M | 374,897 | 0.02% | 31q | -7.3%-$2.4M |
| EVENTIDE ASSET MANAGEMENT, LLC | $30.2M | 370,000 | 0.40% | 3q | HELD |
| AMERICAN CENTURY COMPANIES INC | $29.7M | 364,211 | 0.01% | 3q | -44.1%-$23.4M |
| CITIGROUP INC | $26.9M incl. $5.3M options CALL+PUT | 264,678 | 0.01% | 31q | +5.2%+$1.3M |
| CITADEL ADVISORS LLC | $26.6M CALL+PUT | options only | 0.00% | 31q | OPTIONS |
| Caption Management, LLC | $26.2M CALL+PUT | options only | 0.12% | 3q | OPTIONS |
| LPL Financial LLC | $25.3M | 310,761 | 0.01% | 28q | +140.0%+$14.8M |
| Artisan Partners Limited Partnership | $25.3M | 310,706 | 0.04% | new | NEW |
| MARSHALL WACE, LLP | $24.9M | 305,031 | 0.02% | 7q | +69.9%+$10.2M |
| SEI INVESTMENTS CO | $24.5M | 300,619 | 0.02% | 6q | +47.9%+$7.9M |
| NORDEA INVESTMENT MANAGEMENT AB | $23.6M | 284,175 | 0.02% | 22q | -7.3%-$1.8M |
| Russell Investments Group, Ltd. | $23.2M | 284,096 | 0.02% | 30q | +63.3%+$9.0M |
| California Public Employees Retirement System | $20.9M | 256,314 | 0.01% | 2q | HELD |
| Squarepoint Ops LLC | $20.9M | 255,907 | 0.02% | new | NEW |
| ENVESTNET ASSET MANAGEMENT INC | $20.7M | 254,228 | 0.00% | 4q | +280.9%+$15.3M |
| Aberdeen Group plc | $20.5M | 251,968 | 0.03% | 9q | -30.8%-$9.1M |
| Swiss National Bank | $19.5M | 238,900 | 0.01% | 31q | -1.3%-$252.7K |
| Legal & General Group Plc | $19.3M | 237,216 | 0.00% | 31q | +3.5%+$661.8K |
| Privium Fund Management B.V. | $19.1M | 234,222 | 3.51% | 19q | -36.2%-$10.8M |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $17.8M | 218,133 | 0.01% | 5q | -62.8%-$30.1M |
| Life Cycle Investment Partners Ltd | $17.0M | 209,068 | 0.08% | new | NEW |
| HSBC HOLDINGS PLC | $16.8M | 203,800 | 0.01% | 2q | +34.9%+$4.3M |
| Woodline Partners LP | $16.3M | 200,184 | 0.05% | 14q | HELD |
| Integral Health Asset Management, LLC | $16.3M | 200,000 | 0.64% | 4q | -33.3%-$8.2M |
| AQR CAPITAL MANAGEMENT LLC | $15.8M | 198,842 | 0.01% | 6q | +18.9%+$2.5M |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | $15.6M | 191,432 | 0.15% | 29q | +3.9%+$581.0K |
| PINNACLE ASSOCIATES LTD | $13.9M | 170,131 | 0.15% | 6q | -3.0%-$434.0K |
| RAYMOND JAMES FINANCIAL INC | $13.8M | 169,913 | 0.00% | 7q | -6.9%-$1.0M |
| WCM INVESTMENT MANAGEMENT, LLC | $13.8M | 171,232 | 0.02% | 3q | HELD |
| SEB Asset Management AB | $12.9M | 158,205 | 0.05% | 2q | HELD |
| Clearbridge Investments, LLC | $12.8M | 157,110 | 0.01% | 6q | -22.4%-$3.7M |
| AMERIPRISE FINANCIAL INC | $12.7M | 155,908 | 0.00% | 29q | -18.4%-$2.9M |
| Affinity Asset Advisors, LLC | $12.2M | 150,000 | 0.55% | 3q | -25.0%-$4.1M |
| BFC Planning, Inc. | $12.2M | 149,691 | 0.50% | new | NEW |
| DEUTSCHE BANK AG\ | $12.2M | 149,240 | 0.00% | 34q | -42.6%-$9.0M |
| WEALTH EFFECTS LLC | $12.0M | 147,300 | 3.24% | 19q | +2.8%+$326.0K |
| Retirement Systems of Alabama | $11.9M | 145,687 | 0.04% | 2q | -15.1%-$2.1M |
| TORONTO DOMINION BANK | $11.8M | 144,928 | 0.01% | 2q | -3.6%-$436.1K |
| HighTower Advisors, LLC | $11.4M | 140,394 | 0.01% | 31q | -4.1%-$494.6K |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $11.4M | 139,826 | 0.01% | 31q | -3.1%-$365.7K |
| Ikarian Capital, LLC | $11.3M incl. $8.2M options PUT | 38,278 | 1.21% | 2q | HELD |
| Weiss Asset Management LP | $10.9M | 134,014 | 0.11% | new | NEW |
| BANK OF NOVA SCOTIA | $10.9M | 133,805 | 0.02% | 2q | -1.6%-$175.7K |
| ALLIANCEBERNSTEIN L.P. | $10.9M | 173,265 | 0.00% | 31q | -38.2%-$6.7M |
| PFM Health Sciences, LP | $10.7M | 131,667 | 0.92% | 2q | +104.8%+$5.5M |
| Tetragon Partners GP Ltd | $10.6M | 130,484 | 1.67% | 4q | +2.6%+$267.8K |
| WELLS FARGO & COMPANY/MN | $10.5M | 128,789 | 0.00% | 31q | -18.7%-$2.4M |
| Rhenman & Partners Asset Management AB | $10.4M | 128,000 | 0.98% | 3q | -11.4%-$1.3M |
Showing the largest 100 of 512 reported holders.
What the insiders did
Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.
Officers and directors
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-08-18 | PERRY MICHAEL S | Director | Sold | 11,600 | $1.0M |
| 2026-05-12 | Lu Hongbo | Director | Sold | 2,970 | $228.3K |
| 2026-08-18 | OLUKOTUN ADEOYE Y | Director | Sold | 2,000 | $173.9K |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 112 | $143.8M | 2,197,955 | 15 | 34 | 32 | 0.1% |
| Q2 2026 | 512 | $10.0B | 119,719,661 | 123 | 153 | 153 | 2.2% |
| Q1 2026 | 446 | $7.7B | 120,858,505 | 99 | 165 | 112 | 2.1% |
| Q4 2025 | 408 | $7.9B | 116,022,876 | 113 | 120 | 112 | 2.5% |
| Q3 2025 | 308 | $3.9B | 111,711,989 | 63 | 94 | 80 | 1.3% |
| Q2 2025 | 284 | $1.7B | 106,155,137 | 57 | 91 | 80 | 1.1% |
| Q1 2025 | 264 | $1.4B | 105,286,312 | 40 | 87 | 78 | 0.8% |
| Q4 2024 | 271 | $1.9B | 99,747,960 | 31 | 86 | 81 | 1.2% |
| Q3 2024 | 274 | $2.0B | 100,002,915 | 33 | 88 | 85 | 0.6% |
| Q2 2024 | 273 | $2.7B | 100,057,799 | 32 | 90 | 87 | 2.1% |
| Q1 2024 | 279 | $2.9B | 101,652,575 | 41 | 104 | 73 | 1.4% |
| Q4 2023 | 269 | $2.5B | 81,164,339 | 32 | 70 | 89 | 1.4% |
| Q3 2023 | 259 | $2.0B | 74,810,898 | 20 | 82 | 88 | 0.7% |
| Q2 2023 | 277 | $2.6B | 72,377,940 | 45 | 69 | 103 | 1.1% |
| Q1 2023 | 258 | $1.9B | 74,615,848 | 31 | 82 | 84 | 0.9% |
| Q4 2022 | 286 | $3.0B | 73,247,487 | 38 | 86 | 102 | 1.4% |
| Q3 2022 | 266 | $14.7B | 443,079,828 | 26 | 87 | 84 | 0.2% |
| Q2 2022 | 266 | $5.0B | 142,882,822 | 22 | 97 | 88 | 0.7% |
| Q1 2022 | 294 | $6.5B | 139,968,155 | 35 | 107 | 92 | 0.8% |
| Q4 2021 | 308 | $11.9B | 176,381,333 | 40 | 94 | 96 | 1.3% |
| Q3 2021 | 289 | $11.0B | 175,505,029 | 27 | 99 | 95 | 0.9% |
| Q2 2021 | 312 | $15.3B | 183,746,427 | 57 | 87 | 104 | 0.9% |
| Q1 2021 | 281 | $11.7B | 177,338,094 | 24 | 80 | 118 | 0.7% |
| Q4 2020 | 310 | $11.3B | 143,454,329 | 60 | 82 | 105 | 2.3% |
| Q3 2020 | 263 | $6.4B | 146,702,045 | 40 | 73 | 95 | 1.3% |
| Q2 2020 | 246 | $6.9B | 157,572,015 | 39 | 88 | 79 | 1.3% |
| Q1 2020 | 238 | $7.7B | 264,690,761 | 32 | 83 | 85 | 0.7% |
| Q4 2019 | 289 | $10.6B | 164,830,998 | 78 | 79 | 86 | 1.7% |
| Q3 2019 | 222 | $3.5B | 121,816,396 | 41 | 80 | 59 | 1.5% |
| Q2 2019 | 213 | $3.2B | 115,886,298 | 65 | 74 | 50 | 2.7% |
| Q1 2019 | 174 | $1.8B | 96,242,975 | 35 | 52 | 59 | 1.3% |
| Q4 2018 | 158 | $1.2B | 96,328,583 | 2 | 4 | 2 | 1.2% |