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DaveManuel.com · Institutional Ownership · Who Owns It

AVALO THERAPEUTICS INC (AVTX)

Institutional ownership reported to the SEC as of Q2 2026, across 21 quarters.

129
Reporting holders
$1.4B
Reported value
135.4%
Of shares outstanding
0.7%
Calls
0.6%
Puts
+26
Holder change

Institutions report 72,612,565 shares against 53,629,989 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.

Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.

Holders

Download these holders as CSV

FilerValueShares Their book Held Change
FMR LLC$94.3M5,100,2160.00%3q+77.1%+$41.0M
BlackRock, Inc.$80.7M4,365,5530.00%8q+1234.7%+$74.6M
Nantahala Capital Management, LLC$68.8M3,724,5001.14%6q+201.6%+$46.0M
Deep Track Capital, LP$66.7M3,610,0000.97%newNEW
Caligan Partners LP$58.5M3,163,8662.75%4q+93.5%+$28.3M
TCG Crossover Management, LLC$55.8M3,017,1201.34%8q+308.6%+$42.1M
Affinity Asset Advisors, LLC$53.6M2,900,0002.42%10q+116.3%+$28.8M
STATE STREET CORP$53.4M2,889,2870.00%4q+3932.3%+$52.1M
FARALLON CAPITAL MANAGEMENT, L.L.C.$46.2M2,498,0000.21%2q+172.7%+$29.2M
Point72 Asset Management, L.P.$44.1M2,387,0260.05%4q+160.6%+$27.2M
Avoro Capital Advisors LLC$43.1M2,333,3330.39%2q+65.5%+$17.1M
VANGUARD CAPITAL MANAGEMENT LLC$41.8M2,264,2460.00%2q+214.6%+$28.5M
BVF INC/IL$38.4M2,075,5450.98%8q+27.1%+$8.2M
BANK OF AMERICA CORP /DE/$35.4M1,913,8290.00%9q+197.6%+$23.5M
ADAGE CAPITAL PARTNERS GP, L.L.C.$32.0M1,729,0000.04%4q+102.5%+$16.2M
Soleus Capital Management, L.P.$30.6M1,654,9781.05%3q+274.4%+$22.4M
BRAIDWELL LP$30.1M1,629,1821.11%newNEW
PRICE T ROWE ASSOCIATES INC /MD/$24.2M1,311,7150.00%newNEW
ALLIANCEBERNSTEIN L.P.$23.3M1,260,6890.01%newNEW
UBS Group AG$22.3M1,209,0590.00%11q+5.9%+$1.2M
Logos Global Management LP$21.3M1,150,0000.91%2q+283.3%+$15.7M
GEODE CAPITAL MANAGEMENT, LLC$20.4M1,105,1180.00%8q+550.5%+$17.3M
Commodore Capital LP$18.8M1,018,3191.12%9q+110.8%+$9.9M
RA CAPITAL MANAGEMENT, L.P.$18.5M1,000,0000.16%8q+50.8%+$6.2M
GOLDMAN SACHS GROUP INC$17.5M946,3200.00%3q+1474.4%+$16.4M
Trails Edge Capital Partners, LP$16.5M891,8812.62%newNEW
AMERIPRISE FINANCIAL INC$16.5M891,4050.00%4q+417.8%+$13.3M
Balyasny Asset Management L.P.$15.9M861,7110.02%4q+17.8%+$2.4M
Vestal Point Capital, LP$14.3M775,0000.33%newNEW
Seven Fleet Capital Management LP$14.2M770,7652.35%3q+260.5%+$10.3M
Parkman Healthcare Partners LLC$14.2M766,2901.45%newNEW
BOOTHBAY FUND MANAGEMENT, LLC$13.0M702,0510.17%5q+116.5%+$7.0M
Squarepoint Ops LLC$10.9M589,2450.01%3q+624.9%+$9.4M
Caption Management, LLC$10.3M
incl. $6.4M options PUT
210,0000.05%3q-53.8%-$12.0M
BAKER BROS. ADVISORS LP$10.2M550,0000.05%newNEW
SILVERARC CAPITAL MANAGEMENT, LLC$9.2M500,4020.96%newNEW
Davern Capital Partners, LP$8.7M468,6661.48%newNEW
CITADEL ADVISORS LLC$8.3M
incl. $2.3M options CALL+PUT
323,8330.00%4q+67.2%+$3.3M
Pivotal bioVenture Partners Investment Advisor LLC$8.0M434,0332.61%2q+46.7%+$2.6M
FRANKLIN RESOURCES INC$7.5M404,1910.00%newNEW
Boxer Capital Management, LLC$6.9M375,0000.52%4q+25.0%+$1.4M
RENAISSANCE TECHNOLOGIES LLC$6.6M357,2000.01%4q+197.4%+$4.4M
NORTHERN TRUST CORP$6.4M344,5210.00%7q+1027.5%+$5.8M
DV EQUITIES, LLC$6.1M332,2130.88%newNEW
VANGUARD FIDUCIARY TRUST CO$6.0M324,8080.00%2q+275.8%+$4.4M
Velan Capital Investment Management LP$6.0M324,4523.65%7q+75.3%+$2.6M
Schonfeld Strategic Advisors LLC$5.7M310,0080.02%newNEW
SUSQUEHANNA INTERNATIONAL GROUP, LLP$5.3M
incl. $4.8M options CALL+PUT
27,2270.00%4qHELD
VANGUARD PORTFOLIO MANAGEMENT LLC$5.3M284,7020.00%newNEW
Vivo Capital, LLC$5.1M275,0000.46%newNEW
Eagle Health Investments LP$4.3M235,0930.72%newNEW
SPHERA FUNDS MANAGEMENT LTD.$4.3M232,2940.56%newNEW
PERCEPTIVE ADVISORS LLC$4.1M219,8130.06%6q+57.4%+$1.5M
Jump Financial, LLC$3.7M201,9020.03%3q+1476.1%+$3.5M
NAN FUNG TRINITY (HK) LTD$3.5M189,0000.34%3qHELD
ACUTA CAPITAL PARTNERS, LLC$3.4M186,3082.40%2q+206.4%+$2.3M
Walleye Capital LLC$3.4M185,6130.01%newNEW
RTW INVESTMENTS, LP$3.2M175,0000.03%2q-79.6%-$12.6M
Ally Bridge Group (NY) LLC$2.8M150,0002.45%newNEW
CHARLES SCHWAB INVESTMENT MANAGEMENT INC$2.5M137,4750.00%2q+1274.8%+$2.4M
BNP PARIBAS FINANCIAL MARKETS$2.5M134,0870.00%10q-68.3%-$5.3M
CenterBook Partners LP$2.5M132,8690.12%newNEW
MORGAN STANLEY$2.4M128,0750.00%11q-20.6%-$615.7K
Moody Aldrich Partners LLC$2.3M125,5820.42%3q-21.2%-$623.6K
LMR Partners LLP$2.3M CALL+PUToptions only0.01%newOPTIONS
HighVista Strategies LLC$2.3M122,6100.52%4q+109.2%+$1.2M
Aberdeen Group plc$2.3M122,1690.00%4q-28.8%-$914.9K
SECTORAL ASSET MANAGEMENT INC$2.2M119,9231.55%newNEW
WELLINGTON MANAGEMENT GROUP LLP$1.9M105,2610.00%newNEW
Bank of New York Mellon Corp$1.9M102,6530.00%newNEW
Nuveen, LLC$1.9M100,6330.00%newNEW
Ikarian Capital, LLC$1.7M90,1830.18%10qHELD
TD Asset Management Inc$1.4M77,4740.00%2q+50.7%+$481.7K
CITIGROUP INC$1.3M69,0140.00%newNEW
TWO SIGMA INVESTMENTS, LP$1.2M67,0940.00%5q+4.1%+$49.3K
JANE STREET GROUP, LLC$1.1M CALLoptions only0.00%3qOPTIONS
Rafferty Asset Management, LLC$1.0M56,4110.00%newNEW
MANUFACTURERS LIFE INSURANCE COMPANY, THE$994.2K53,7990.00%newNEW
RHUMBLINE ADVISERS$984.8K53,2900.00%newNEW
XTX Topco Ltd$971.7K52,5830.01%4q-58.5%-$1.4M
DEUTSCHE BANK AG\$760.7K41,1660.00%3q-72.6%-$2.0M
DIMENSIONAL FUND ADVISORS LP$706.9K38,1580.00%2q-6.5%-$49.3K
Verition Fund Management LLC$706.7K38,2400.00%newNEW
Man Group plc$681.5K36,8760.00%2q-20.8%-$178.8K
WELLS FARGO & COMPANY/MN$675.9K36,5760.00%2qHELD
Verdad Advisers, LP$606.6K32,8270.58%newNEW
SIMPLEX TRADING, LLC$574.7K CALL+PUToptions only0.00%5qOPTIONS
PROFUND ADVISORS LLC$523.1K28,3090.01%newNEW
GLENMEDE TRUST CO NA$522.6K28,2800.00%3q+9.9%+$47.1K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.$480.5K25,7120.00%newNEW
Persistent Asset Partners Ltd$453.6K24,5440.14%3q+210.0%+$307.2K
MetLife Investment Management, LLC$452.7K24,4990.00%newNEW
ENVESTNET ASSET MANAGEMENT INC$416.5K22,5390.00%3q+12.7%+$47.0K
Invesco Ltd.$410.7K22,2260.00%newNEW
Virtus Investment Advisers, LLC$409.7K22,1680.10%newNEW
JPMORGAN CHASE & CO$404.0K
incl. $54.0K options PUT
18,1450.00%11q-90.7%-$3.9M
Vanguard Global Advisers, LLC$369.8K20,0100.00%2q+257.0%+$266.2K
SEI INVESTMENTS CO$331.4K17,9310.00%2q-68.5%-$719.3K
BARCLAYS PLC$329.1K17,8110.00%4q+21.6%+$58.6K
ExodusPoint Capital Management, LP$304.8K16,4950.00%3q-7.1%-$23.2K

Five percent filings

Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →

FiledFormFiler % of class
2026-10-2913GTrails Edge Capital Partners, LPwith 2 co-filers5.2%

What the insiders did

Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.

Officers and directors

DateInsiderRoleSideSharesValue
2026-08-17Sullivan Christopher RyanChief Financial OfficerSold41,694$828.1K ×2
2026-08-18Sullivan Christopher RyanChief Financial OfficerSold31,031$622.3K
2026-09-16Sullivan Christopher RyanChief Financial OfficerSold12,394$202.4K
2026-09-10Sullivan Christopher RyanChief Financial OfficerSold10,185$179.5K

Quarter by quarter

Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.

QuarterHoldersValue SharesNewAdded TrimmedOptions
Q3 202616$1.6M103,5879120.0%
Q2 2026129$1.4B72,612,5655447161.3%
Q1 2026103$514.9M31,239,1923331219.5%
Q4 202586$370.5M19,885,5173227142.5%
Q3 202565$196.8M15,319,258331581.0%
Q2 202536$39.2M7,843,04059120.0%
Q1 202533$66.1M8,255,0574840.0%
Q4 202433$56.0M7,530,5217820.0%
Q3 202428$63.2M6,656,9359310.0%
Q2 202421$9.6M771,1047440.0%
Q1 202418$1.9M87,5878430.0%
Q4 202312$209.8K23,01212000.0%
Q3 202326$158.9K1,339,66610550.0%
Q2 202325$862.7K2,427,6915650.0%
Q1 202331$16.0M9,130,9839750.0%
Q4 202227$28.0M5,550,97912240.0%
Q3 202216$18.4M5,548,65817000.0%
Q2 202244$34.7M69,408,11297180.0%
Q1 202264$56.2M77,717,621710280.0%
Q4 202171$136.5M80,056,2021529130.3%
Q3 202174$196.2M89,787,50576000.2%