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DaveManuel.com · Institutional Ownership · 13F Holdings

BRAIDWELL LP

Reported holdings as of Q2 2026, from 15 quarterly filings.

CIK
1920938
Reported value
$2.7B
Positions
86
Top 10 weight
31.6%
Filed
2026-08-14
Days after quarter end
45

Holdings

Download these holdings as CSV

SecurityTickerValue SharesWeightWeight change Held Change
CARIS LIFE SCIENCES INCCAI$147.1M8,256,0325.44%+0.66pp5q+3.1%+$4.4M
HINGE HEALTH INCHNGE$110.4M1,330,1274.08%+2.21pp4q-8.6%-$10.4M
GLAUKOS CORPGKOS$82.7M591,9273.06%+0.32pp15q-22.5%-$24.0M
EDGEWISE THERAPEUTICS INCEWTX$81.1M1,996,9653.00%+0.53pp8q-14.9%-$14.2M
SPYRE THERAPEUTICS INCSYRE$78.1M879,4672.89%+1.32pp11q-5.7%-$4.7M
IRHYTHM HOLDINGS INCIRTC$77.8M654,2622.88%+0.48pp15q+7.2%+$5.2M
NEOGENOMICS INCNEO$71.8M4,918,2022.65%+1.26pp4q-12.4%-$10.2M
KODIAK SCIENCES INCKOD$69.6M1,787,3182.58%+0.26pp3q-1.7%-$1.2M
XENON PHARMACEUTICALS INCXENE$68.3M1,131,4522.53%-0.07pp15q-15.5%-$12.5M
ALPHATEC HLDGS INC$66.2M69,121,0002.45%+0.33pp2qDEBT
MONTE ROSA THERAPEUTICS INCGLUE$59.3M2,451,5622.19%+0.43pp3q-23.5%-$18.3M
DIANTHUS THERAPEUTICS INCDNTH$58.0M594,5622.14%-0.37pp4q-33.9%-$29.7M
NEUROCRINE BIOSCIENCES INCNBIX$56.7M336,1712.10%-0.77pp14q-48.4%-$53.2M
ALPHATEC HLDGS INCATEC$56.5M6,531,4392.09%+1.30pp2q+200.6%+$37.7M
GENERATE BIOMEDICINES INCGENB$55.4M3,283,8442.05%+0.55pp2q-8.6%-$5.2M
MARAVAI LIFESCIENCES HLDGS IMRVI$54.3M8,702,9212.01%+1.04pp13q-15.0%-$9.6M
KRYSTAL BIOTECH INCKRYS$47.9M128,9751.77%+0.20pp15q-29.3%-$19.9M
HUMANA INCHUM$45.5M114,5001.68%-newNEW
THERMO FISHER SCIENTIFIC INCTMO$44.8M89,3951.66%+0.13pp7q-3.8%-$1.8M
KYMERA THERAPEUTICS INCKYMR$43.4M378,1631.60%+0.67pp4q+12.0%+$4.7M
RHYTHM PHARMACEUTICALS INCRYTM$42.3M381,1281.57%+0.66pp2q+22.7%+$7.8M
DAMORA THERAPEUTICS INC COM NEWDMRA$42.1M1,620,3771.56%+0.79pp2q+81.1%+$18.9M
ACADIA PHARMACEUTICALS INCACAD$41.7M1,646,3991.54%-0.29pp4q-33.4%-$20.9M
BRIGHTSPRING HEALTH SVCS INCBTSG$41.6M596,7531.54%+0.09pp3q-41.3%-$29.3M
TRANSMEDICS GROUP INCTMDX$40.5M609,7151.50%+0.41pp7q+85.1%+$18.6M
MBX BIOSCIENCES INCMBX$39.2M710,8801.45%-0.03pp3q-52.4%-$43.1M
Climb Bio IncCLYM$36.5M2,797,3751.35%+1.00pp2q+82.9%+$16.5M
CAREDX INCCDNA$34.8M1,220,6021.29%+0.03pp4q-43.8%-$27.1M
MAZE THERAPEUTICS INCMAZE$34.0M1,140,0401.26%-newNEW
BRIGHT MINDS BIOSCIENCES INCDRUG$34.0M483,8221.26%-0.06pp4q-10.4%-$3.9M
ACADIA HEALTHCARE COACHC$33.7M1,141,4771.25%+0.74pp2q+76.7%+$14.6M
NEKTAR THERAPEUTICSNKTR$33.1M473,6171.22%+0.69pp2q+112.7%+$17.5M
CORVUS PHARMACEUTICALS INCCRVS$31.8M2,126,2981.18%+0.32pp2q+21.3%+$5.6M
NURIX THERAPEUTICS INCNRIX$31.2M1,286,7691.15%+0.25pp3q-26.5%-$11.3M
INSPIRE MED SYS INCINSP$30.2M677,5701.12%-0.05pp12qHELD
AVALO THERAPEUTICS INCAVTX$30.1M1,629,1821.11%-newNEW
ALAMAR BIOSCIENCES INC COMMON STOCKALMR$29.4M1,083,9831.09%-newNEW
DANAHER CORP DELDHR$28.7M150,6271.06%+0.18pp6q+8.1%+$2.2M
INTUITIVE SURGICAL INCISRG$27.9M70,1371.03%-0.16pp10q-9.3%-$2.8M
ORUKA THERAPEUTICS INCORKA$26.5M278,1640.98%-newNEW
AVALYN PHARMACEUTICALS INC COM SHSAVLN$26.4M801,3950.98%-newNEW
AVEANNA HEALTHCARE HLDGS INCAVAH$26.3M3,065,1060.97%+0.50pp2q+39.1%+$7.4M
BIOAGE LABS INCBIOA$25.3M1,033,1290.94%+0.24pp2q-13.9%-$4.1M
BOSTON SCIENTIFIC CORPBSX$25.1M587,5670.93%+0.20pp2q+69.6%+$10.3M
VERA THERAPEUTICS INCVERA$24.2M564,7240.90%+0.19pp4q+7.8%+$1.8M
REPLIGEN CORPRGEN$24.2M177,1000.89%+0.71pp13q+272.8%+$17.7M
ZURA BIO LTDZURA$23.5M3,980,2950.87%+0.08pp8qHELD
GUARDANT HEALTH INCGH$22.2M147,8500.82%-0.72pp2q-70.4%-$52.8M
EVOLUS INCEOLS$21.9M3,155,2090.81%+0.38pp3q+1.6%+$347.0K
NATERA INCNTRA$21.6M79,5000.80%-0.06pp3q-38.4%-$13.4M
ORTHOPEDIATRICS CORPKIDS$21.1M1,100,3700.78%+0.20pp15qHELD
ELEVANCE HEALTH INC FORMERLYELV$20.9M53,9600.77%+0.17pp2q-13.1%-$3.1M
TECTONIC THERAPEUTIC INCTECX$20.5M596,9000.76%-0.11pp4q-29.5%-$8.6M
DYNE THERAPEUTICS INCDYN$20.5M921,5980.76%-0.26pp7q-45.2%-$16.9M
NEOGENOMICS INC$16.9M18,011,0000.62%-2.44pp15qDEBT
IMMUNOCORE HLDGS PLCIMCR$16.6M521,3270.61%-newNEW
REPLIGEN CORP$16.4M16,000,0000.61%-2.68pp7qDEBT
ARGENX SEARGX$16.4M17,7070.61%-1.46pp11q-79.2%-$62.4M
CELLDEX THERAPEUTICS INC NEWCLDX$16.2M436,6460.60%-0.83pp4q-67.8%-$34.2M
OVID THERAPEUTICS INCOVID$15.9M5,919,4640.59%-newNEW
MANNKIND CORPMNKD$14.7M3,458,4290.54%-newNEW
UNIQURE NVQURE$13.9M301,6520.51%-newNEW
X4 PHARMACEUTICALS INCXFOR$13.6M2,922,7540.50%+0.05pp3q-10.7%-$1.6M
ORIC PHARMACEUTICALS INCORIC$13.2M1,214,5400.49%+0.01pp2q+7.7%+$936.8K
KINIKSA PHARMACEUTICALS INTLKNSA$11.8M183,8220.43%flat9q-32.5%-$5.7M
OCULIS HOLDING AGOCS$11.6M834,1830.43%-newNEW
ACLARIS THERAPEUTICS INCACRS$11.3M2,142,3480.42%+0.21pp2q+26.1%+$2.3M
SEAPORT THERAPEUTICS INC COMMON STOCKSPTX$10.9M500,0000.40%-newNEW
VOR BIOPHARMA INCVOR$10.6M573,1040.39%+0.11pp2q+22.8%+$2.0M
SURROZEN INCSRZN$10.1M390,7530.38%-0.01pp5q-1.3%-$138.8K
IMMUNIC INCIMUX$9.9M645,0100.37%-newNEW
HELIX ACQUISITION CORP IIIHLXC$9.5M900,0000.35%+0.04pp2qHELD
IONIS PHARMACEUTICALS INCIONS$9.3M116,7620.34%+0.01pp2q-10.8%-$1.1M
QUEST DIAGNOSTICS INCDGX$9.2M43,2000.34%-newNEW
ADLAI NORTYE LTDANL$9.1M795,2140.34%-newNEW
TENAX THERAPEUTICS INCTENX$8.5M584,4120.31%-newNEW
KARDIGAN INCKARD$7.2M300,0000.26%-newNEW
Amanat Acquisition CorpAMAN$7.1M700,0000.26%-newNEW
HEMAB THERAPEUTICS HLDGS INC COM SHSCOAG$5.9M160,0000.22%-newNEW
GH RESEARCH PLCGHRS$5.6M207,2400.21%-newNEW
WATERS CORPWAT$5.3M14,0400.19%-newNEW
RESEARCH ALLIANCE CORP IIIRACC$4.3M400,0000.16%-newNEW
JATT II ACQUISITION CORPJATT$2.8M250,0000.11%-newNEW
PULMONX CORPLUNG$978.3K752,5410.04%flat15qHELD
VYNE THERAPEUTICS INCVYNE$596.1K916,0770.02%flat2qHELD
CYCLERION THERAPEUTICS INCCYCN$531.9K156,8900.02%-newNEW

By sector

Industry comes from the SIC code on each company's own SEC filings, which is self-reported and sometimes out of date. Derivative exposure is counted with the shares. Securities the SEC assigns no industry - funds, trusts, foreign issues - are shown as not classified rather than dropped.

Biotech & Pharma 57.8%Medical Devices 13.4%Healthcare Services 12.4%Software & IT Services 4.1%Instruments & Controls 2.7%Business Services 2.7%Insurance 2.5%Other sectors 0.7%Not classified 3.7%
 
SectorValueShare
Biotech & Pharma$1.6B57.8%
Medical Devices$362.8M13.4%
Healthcare Services$336.4M12.4%
Software & IT Services$110.4M4.1%
Instruments & Controls$73.5M2.7%
Business Services$71.8M2.7%
Insurance$66.3M2.5%
Other sectors$19.5M0.7%
Not classified$100.6M3.7%

What the disclosed book did

This is not the fund's return. A 13F shows long US equity positions only, so shorts, bonds, foreign listings, private holdings and cash are all invisible here. What this measures is the quarter's change in value of the positions this manager disclosed, had they been left untouched - the return a reader following the filing would have earned.

QuarterBookMarket DifferencePriced
Q2 2026+24.7%+14.8%+9.9%84%
Q1 2026+0.4%-4.6%+5.0%82%
Q4 2025+18.7%+2.4%+16.4%73%
Q3 2025+14.1%+7.8%+6.3%72%
Q2 2025+5.3%+10.5%-5.1%67%
Q1 2025-15.7%-4.6%-11.1%66%
Q4 2024-7.0%+2.1%-9.1%66%
Q3 2024+9.4%+5.4%+4.0%61%

Market is SPY over the same two quarter ends, priced the same way as everything else here - the median across every filer reporting it. It is a large-cap US proxy, so a manager holding small caps or biotech will beat or trail it for reasons that are not skill. Prices are quarter-end to quarter-end and say nothing about the path in between, or about trades opened and closed inside a quarter.

Quarter by quarter

QuarterValuePositions NewAddedTrimmed ExitedTop 10 Days to file
Q2 2026$2.7B862421352631.6%45
Q1 2026$3.0B883119321630.4%45
Q4 2025$3.1B732016322037.9%48
Q3 2025$3.4B7325923744.1%45
Q2 2025$2.9B55713191645.8%45
Q1 2025$2.8B641316202240.1%45
Q4 2024$3.4B731423172237.5%45
Q3 2024$3.5B811626231034.6%45
Q2 2024$3.2B752230131736.7%45
Q1 2024$3.1B701721161937.8%45
Q4 2023$2.7B72820282140.3%45
Q3 2023$3.2B851931131535.4%45
Q2 2023$3.1B811824201837.0%45
Q1 2023$3.0B811421272136.5%45
Q4 2022$3.0B88000033.0%45

Rows marked UNVERIFIED ID, PLACEHOLDER ID, TICKER AS ID or NON-CUSIP ID carry an identifier that is not a valid CUSIP. They are shown because the filer reported that money, but treat the security named with caution - hover the chip for what is wrong with it, and see the methodology.

Held counts consecutive filings in which this manager reported the position, and can reach further back than the quarters listed above: the tabs begin at Q4 2018 because earlier coverage is too sparse to describe a market, but tenure is counted over every filing we hold, some reaching to 2007. A position sold and later rebought starts again from one.

Weight change is the shift in this position's share of the whole book, in percentage points. It is the more useful column: when money flows into or out of a broad fund, almost every holding is bought or sold at once, so added and trimmed largely track flows. A weight that rose while the book shrank is a decision. Both compare with the previous quarter this filer reported, not the previous calendar quarter.