KYMERA THERAPEUTICS INC (KYMR)
Institutional ownership reported to the SEC as of Q2 2026, across 25 quarters.
Institutions report 97,011,589 shares against 83,150,618 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| FMR LLC | $1.4B | 12,349,256 | 0.06% | 24q | +5.5%+$74.5M |
| BAKER BROS. ADVISORS LP | $992.7M | 8,657,242 | 4.97% | 24q | HELD |
| Avoro Capital Advisors LLC | $857.1M | 7,474,747 | 7.70% | 20q | HELD |
| PRICE T ROWE ASSOCIATES INC /MD/ | $815.6M | 7,112,980 | 0.08% | 24q | +17.4%+$120.6M |
| T. Rowe Price Investment Management, Inc. | $717.5M | 6,257,261 | 0.47% | 5q | +14.5%+$90.8M |
| BlackRock, Inc. | $635.1M | 5,538,210 | 0.01% | 8q | +9.4%+$54.7M |
| BVF INC/IL | $444.0M | 3,872,052 | 11.35% | 24q | -29.6%-$187.0M |
| WELLINGTON MANAGEMENT GROUP LLP | $421.4M | 3,675,028 | 0.07% | 24q | -5.5%-$24.6M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $343.1M | 2,992,193 | 0.02% | 2q | +4.1%+$13.5M |
| Siren, L.L.C. | $336.7M | 2,935,830 | 6.81% | 8q | -7.9%-$28.8M |
| VANGUARD CAPITAL MANAGEMENT LLC | $336.3M | 2,932,378 | 0.01% | 2q | +1.8%+$6.0M |
| Atlas Venture Life Science Advisors, LLC | $326.5M | 2,847,541 | 37.05% | 19q | -37.8%-$198.4M |
| STATE STREET CORP | $313.9M | 2,737,226 | 0.01% | 23q | +14.5%+$39.8M |
| GEODE CAPITAL MANAGEMENT, LLC | $208.3M | 1,816,331 | 0.01% | 24q | +10.4%+$19.6M |
| Capital Research Global Investors | $159.3M | 1,388,881 | 0.02% | 6q | -17.0%-$32.6M |
| GOLDMAN SACHS GROUP INC | $136.2M | 1,187,333 | 0.01% | 24q | +33.6%+$34.3M |
| UBS Group AG | $115.6M | 1,007,777 | 0.01% | 24q | -1.6%-$1.8M |
| Driehaus Capital Management LLC | $105.4M | 919,233 | 0.61% | 9q | -11.9%-$14.3M |
| Merck & Co., Inc. | $88.5M | 772,165 | 16.82% | 7q | HELD |
| NORGES BANK | $86.8M | 757,246 | 0.01% | 22q | +4477.4%+$84.9M |
| FEDERATED HERMES, INC. | $85.9M | 749,398 | 0.12% | 4q | +39.6%+$24.4M |
| DIMENSIONAL FUND ADVISORS LP | $85.4M | 745,152 | 0.02% | 19q | +25.7%+$17.5M |
| FRONTIER CAPITAL MANAGEMENT CO LLC | $85.0M | 740,866 | 0.79% | 8q | -2.5%-$2.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $84.5M | 736,866 | 0.02% | 21q | -15.9%-$15.9M |
| ALLIANCEBERNSTEIN L.P. | $81.8M | 981,521 | 0.03% | 23q | +10.5%+$7.8M |
| Holocene Advisors, LP | $73.0M | 636,579 | 0.16% | 4q | -23.9%-$23.0M |
| NORTHERN TRUST CORP | $66.7M | 581,907 | 0.01% | 23q | +17.7%+$10.0M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $60.7M | 529,729 | 0.01% | 23q | +7.0%+$4.0M |
| FRANKLIN RESOURCES INC | $59.1M | 515,050 | 0.01% | 9q | +42.4%+$17.6M |
| EVENTIDE ASSET MANAGEMENT, LLC | $57.8M | 504,210 | 0.77% | 10q | -19.6%-$14.1M |
| JENNISON ASSOCIATES LLC | $57.7M | 502,978 | 0.03% | 10q | -1.2%-$690.4K |
| Woodline Partners LP | $57.4M | 500,868 | 0.18% | 17q | +146.0%+$34.1M |
| Rock Springs Capital Management LP | $52.0M | 453,156 | 2.54% | 24q | -8.8%-$5.0M |
| VANGUARD FIDUCIARY TRUST CO | $51.6M | 449,731 | 0.01% | 2q | +5.2%+$2.6M |
| Boxer Capital Management, LLC | $49.2M | 429,100 | 3.71% | 7q | +30.4%+$11.5M |
| Pictet Asset Management Holding SA | $45.0M | 395,540 | 0.04% | 5q | -15.6%-$8.3M |
| BANK OF AMERICA CORP /DE/ | $43.4M | 378,286 | 0.00% | 24q | +30.7%+$10.2M |
| BRAIDWELL LP | $43.4M | 378,163 | 1.60% | 4q | +12.0%+$4.7M |
| BNP PARIBAS FINANCIAL MARKETS | $43.1M | 375,868 | 0.01% | 7q | +31.5%+$10.3M |
| TWO SIGMA INVESTMENTS, LP | $42.6M | 371,374 | 0.03% | 19q | +44.8%+$13.2M |
| Clearbridge Investments, LLC | $39.8M | 347,221 | 0.03% | new | NEW |
| Octagon Capital Advisors LP | $35.5M | 310,000 | 3.20% | 5q | -27.1%-$13.2M |
| Nextech Invest Ltd. | $32.0M | 278,896 | 1.52% | 5q | HELD |
| Alyeska Investment Group, L.P. | $31.7M | 276,455 | 0.08% | 5q | -19.3%-$7.6M |
| TD Asset Management Inc | $31.3M | 272,900 | 0.03% | 24q | -4.9%-$1.6M |
| VOYA INVESTMENT MANAGEMENT LLC | $31.0M | 269,914 | 0.03% | 21q | +35.8%+$8.2M |
| Commodore Capital LP | $28.7M | 250,000 | 1.71% | 5q | -66.7%-$57.3M |
| RTW INVESTMENTS, LP | $27.5M | 240,000 | 0.23% | 3q | HELD |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $26.8M | 233,713 | 0.01% | 14q | +11.8%+$2.8M |
| GILDER GAGNON HOWE & CO LLC | $26.3M | 229,053 | 0.27% | 10q | -2.7%-$731.6K |
| Bank of New York Mellon Corp | $24.7M | 215,588 | 0.00% | 23q | +11.6%+$2.6M |
| Polar Capital Holdings Plc | $23.4M | 203,747 | 0.06% | 5q | -5.3%-$1.3M |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $22.9M | 200,000 | 0.03% | 5q | -40.3%-$15.5M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $22.8M incl. $22.3M options CALL+PUT | 5,061 | 0.00% | 16q | -80.1%-$91.8M |
| MORGAN STANLEY | $22.3M | 194,843 | 0.00% | 24q | -8.4%-$2.0M |
| Candriam S.C.A. | $22.1M | 192,880 | 0.10% | 5q | -4.4%-$1.0M |
| CITADEL ADVISORS LLC | $20.1M incl. $7.3M options CALL+PUT | 111,555 | 0.00% | 22q | -5.9%-$1.3M |
| MARSHALL WACE, LLP | $19.2M | 167,517 | 0.02% | new | NEW |
| Eagle Health Investments LP | $19.1M | 166,148 | 3.16% | 3q | +13.9%+$2.3M |
| TimesSquare Capital Management, LLC | $18.0M | 157,327 | 0.27% | 3q | -6.8%-$1.3M |
| Connor, Clark & Lunn Investment Management Ltd. | $17.2M | 149,908 | 0.03% | 2q | +43.8%+$5.2M |
| DIADEMA PARTNERS LP | $17.2M CALL | options only | 2.17% | new | OPTIONS |
| Foresite Capital Management VI LLC | $16.8M | 146,332 | 2.61% | 7q | HELD |
| JANE STREET GROUP, LLC | $16.6M incl. $16.3M options CALL+PUT | 2,957 | 0.00% | 16q | +0.6%+$101.2K |
| WCM INVESTMENT MANAGEMENT, LLC | $16.6M | 151,810 | 0.03% | 3q | HELD |
| Nuveen, LLC | $15.9M | 138,478 | 0.00% | 6q | +8.1%+$1.2M |
| RAYMOND JAMES FINANCIAL INC | $15.5M | 135,584 | 0.00% | new | NEW |
| Deer Management Co. LLC | $14.4M | 125,895 | 1.78% | 19q | HELD |
| Caption Management, LLC | $13.8M PUT | options only | 0.06% | new | OPTIONS |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $13.7M | 119,503 | 0.01% | 23q | -0.5%-$74.3K |
| BOONE CAPITAL MANAGEMENT LLC | $13.0M | 113,173 | 3.04% | new | NEW |
| JPMORGAN CHASE & CO | $12.6M | 113,062 | 0.00% | 23q | -9.9%-$1.4M |
| ARMISTICE CAPITAL, LLC | $12.2M | 106,272 | 0.15% | 3q | +26.7%+$2.6M |
| DEUTSCHE BANK AG\ | $12.2M | 106,049 | 0.00% | 23q | +15.4%+$1.6M |
| Atika Capital Management LLC | $11.9M | 104,000 | 0.78% | new | NEW |
| First Turn Management, LLC | $11.8M | 102,533 | 1.26% | 4q | -59.7%-$17.4M |
| Ensign Peak Advisors, Inc | $11.2M | 97,660 | 0.02% | 5q | -14.2%-$1.9M |
| Squarepoint Ops LLC | $11.1M | 97,189 | 0.01% | 12q | +657.0%+$9.7M |
| Swiss National Bank | $10.3M | 90,100 | 0.01% | 23q | -4.7%-$504.5K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $10.3M | 89,494 | 0.02% | 7q | -13.3%-$1.6M |
| RHUMBLINE ADVISERS | $9.3M | 80,684 | 0.01% | 23q | +12.6%+$1.0M |
| CITIGROUP INC | $8.9M | 77,784 | 0.00% | 23q | +534.2%+$7.5M |
| Burkehill Global Management, LP | $8.6M | 75,000 | 0.31% | 5q | HELD |
| VICTORY CAPITAL MANAGEMENT INC | $8.5M | 74,340 | 0.00% | 10q | +9.3%+$727.6K |
| WELLS FARGO & COMPANY/MN | $8.3M | 72,160 | 0.00% | 23q | +169.6%+$5.2M |
| FIFTH THIRD BANCORP | $7.5M | 65,659 | 0.01% | 2q | +28.1%+$1.7M |
| Yiheng Capital Management, L.P. | $7.3M | 63,440 | 2.50% | 6q | -13.6%-$1.1M |
| Russell Investments Group, Ltd. | $7.1M | 62,233 | 0.01% | 17q | +27.5%+$1.5M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $7.1M | 61,657 | 0.01% | 5q | -4.4%-$322.2K |
| XTX Topco Ltd | $7.1M | 61,501 | 0.09% | new | NEW |
| FIRST TRUST ADVISORS LP | $7.0M | 61,368 | 0.00% | 4q | -34.4%-$3.7M |
| Invesco Ltd. | $7.0M | 60,813 | 0.00% | 21q | -44.9%-$5.7M |
| Nicholas Investment Partners, LP | $6.3M | 54,569 | 0.35% | 4q | +99.5%+$3.1M |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $6.2M | 54,429 | 0.01% | 23q | -3.3%-$212.5K |
| Ikarian Capital, LLC | $5.8M PUT | options only | 0.62% | 2q | OPTIONS |
| SIMPLEX TRADING, LLC | $5.6M incl. $4.9M options CALL+PUT | 5,867 | 0.00% | 21q | HELD |
| Patient Square Capital LP | $5.4M | 47,500 | 0.84% | 6q | -52.5%-$6.0M |
| VANGUARD ASSET MANAGEMENT, Ltd | $5.3M | 45,786 | 0.00% | 2q | +1.8%+$91.3K |
| PEREGRINE CAPITAL MANAGEMENT LLC | $5.2M | 45,671 | 0.17% | new | NEW |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $4.7M | 41,126 | 0.01% | 9q | +7.4%+$322.7K |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-10-27 | 13G/A | BlackRock, Inc. | 6.6% |
What the insiders did
Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.
Officers and directors
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-06-26 | Booth Bruce | Director | Sold | 467,878 | $51.6M ×24 |
| 2026-06-25 | Booth Bruce | Director | Sold | 285,684 | $34.8M ×22 |
| 2026-06-25 | Booth Bruce | Director | Sold | 262,637 | $30.3M ×24 |
| 2026-06-22 | Booth Bruce | Director | Sold | 246,330 | $24.3M ×20 |
| 2026-06-24 | Booth Bruce | Director | Sold | 134,720 | $13.5M ×4 |
| 2026-06-17 | Booth Bruce | Director | Sold | 116,812 | $10.6M ×3 |
| 2026-06-18 | Booth Bruce | Director | Sold | 115,056 | $10.5M ×6 |
| 2026-07-01 | Mainolfi Nello | Chief Executive Officer | Sold | 80,000 | $9.2M ×5 |
| 2026-06-30 | Jacobs Bruce N. | Chief Financial Officer | Sold | 77,109 | $8.9M ×8 |
| 2026-06-29 | Booth Bruce | Director | Sold | 76,650 | $8.3M ×14 |
| 2026-07-07 | Mainolfi Nello | Chief Executive Officer | Sold | 50,000 | $6.0M |
| 2026-06-29 | Booth Bruce | Director | Sold | 45,367 | $4.9M ×6 |
Ten percent owners and entities
Usually an institution that crossed a reporting threshold, or a company taking a strategic stake, rather than an individual with a view.
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-06-26 | BVF PARTNERS L P/IL | Director, Other | Sold | 1,630,658 | $173.7M ×4 |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 45 | $16.8M | 152,980 | 9 | 14 | 9 | 0.0% |
| Q2 2026 | 287 | $11.2B | 97,011,589 | 51 | 99 | 82 | 0.9% |
| Q1 2026 | 261 | $8.0B | 96,291,517 | 38 | 90 | 72 | 0.3% |
| Q4 2025 | 259 | $7.0B | 89,970,109 | 60 | 98 | 63 | 0.3% |
| Q3 2025 | 212 | $4.6B | 81,057,452 | 37 | 80 | 54 | 0.3% |
| Q2 2025 | 213 | $3.5B | 78,957,378 | 63 | 66 | 52 | 0.4% |
| Q1 2025 | 178 | $2.0B | 72,897,037 | 26 | 60 | 54 | 0.7% |
| Q4 2024 | 180 | $2.9B | 71,721,894 | 22 | 60 | 58 | 0.1% |
| Q3 2024 | 177 | $3.3B | 69,192,091 | 35 | 50 | 64 | 0.2% |
| Q2 2024 | 157 | $2.0B | 67,544,996 | 24 | 57 | 48 | 0.1% |
| Q1 2024 | 164 | $2.8B | 68,786,453 | 40 | 57 | 44 | 0.1% |
| Q4 2023 | 138 | $1.6B | 61,409,387 | 31 | 35 | 44 | 0.2% |
| Q3 2023 | 123 | $797.9M | 57,350,132 | 12 | 42 | 35 | 0.1% |
| Q2 2023 | 127 | $1.3B | 58,406,644 | 18 | 43 | 33 | 0.2% |
| Q1 2023 | 128 | $1.7B | 57,530,008 | 15 | 43 | 36 | 1.4% |
| Q4 2022 | 123 | $1.4B | 56,137,066 | 20 | 42 | 39 | 2.7% |
| Q3 2022 | 114 | $1.4B | 65,460,273 | 31 | 39 | 24 | 0.3% |
| Q2 2022 | 97 | $1.2B | 62,196,007 | 12 | 39 | 27 | 0.3% |
| Q1 2022 | 124 | $2.6B | 60,787,756 | 21 | 54 | 31 | 0.5% |
| Q4 2021 | 127 | $3.6B | 56,538,810 | 22 | 54 | 22 | 0.3% |
| Q3 2021 | 115 | $2.9B | 48,610,393 | 22 | 61 | 21 | 0.5% |
| Q2 2021 | 109 | $2.1B | 42,796,537 | 39 | 42 | 15 | 0.4% |
| Q1 2021 | 94 | $1.1B | 27,811,990 | 25 | 27 | 24 | 0.0% |
| Q4 2020 | 74 | $1.4B | 23,472,822 | 34 | 13 | 11 | 0.0% |
| Q3 2020 | 52 | $542.6M | 16,829,476 | 52 | 0 | 0 | 0.0% |
