DaveManuel.com · Institutional Ownership · Who Owns It
ORUKA THERAPEUTICS INC (ORKA)
Institutional ownership reported to the SEC as of Q2 2026, across 9 quarters.
259
Reporting holders
$7.1B
Reported value
112.0%
Of shares outstanding
0.3%
Calls
0.2%
Puts
+74
Holder change
Institutions report 74,139,147 shares against 66,209,699 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| FMR LLC | $862.0M | 9,057,645 | 0.04% | 8q | +21.9%+$154.8M |
| BlackRock, Inc. | $474.9M | 4,990,181 | 0.01% | 8q | +41.5%+$139.2M |
| Venrock Adviser, LLC | $394.8M | 4,148,428 | 11.97% | 8q | HELD |
| Fairmount Funds Management LLC | $352.6M | 3,705,262 | 23.31% | 8q | HELD |
| Capital World Investors | $323.7M | 3,401,639 | 0.04% | new | NEW |
| RTW INVESTMENTS, LP | $298.7M | 3,139,030 | 2.55% | 8q | +52.5%+$102.9M |
| STATE STREET CORP | $254.4M | 2,673,090 | 0.01% | 7q | +65.7%+$100.8M |
| VANGUARD CAPITAL MANAGEMENT LLC | $224.7M | 2,360,971 | 0.00% | 2q | +27.0%+$47.7M |
| Paradigm Biocapital Advisors LP | $204.1M | 2,144,526 | 3.82% | 3q | -7.6%-$16.7M |
| Deep Track Capital, LP | $183.3M | 1,926,000 | 2.67% | 8q | -5.3%-$10.3M |
| Bellevue Group AG | $157.7M | 1,657,190 | 3.32% | 2q | +226.9%+$109.5M |
| FRANKLIN RESOURCES INC | $154.3M | 1,621,451 | 0.03% | 8q | +61.5%+$58.8M |
| Remedium Capital Partners, LLC | $149.0M | 1,565,661 | 32.99% | 3q | HELD |
| RA CAPITAL MANAGEMENT, L.P. | $148.0M | 1,554,597 | 1.29% | new | NEW |
| VIKING GLOBAL INVESTORS LP | $143.1M | 1,503,478 | 0.41% | 4q | -43.6%-$110.7M |
| GEODE CAPITAL MANAGEMENT, LLC | $136.1M | 1,429,954 | 0.01% | 8q | +49.8%+$45.2M |
| Jupiter Topco LLC | $131.0M | 1,375,844 | 0.05% | new | FIRST |
| PERCEPTIVE ADVISORS LLC | $128.0M | 1,345,063 | 1.92% | 4q | -3.6%-$4.8M |
| Polar Capital Holdings Plc | $116.9M | 1,228,609 | 0.28% | 7q | +17.3%+$17.2M |
| CITADEL ADVISORS LLC | $109.7M incl. $3.2M options CALL+PUT | 1,119,011 | 0.01% | 4q | +11.1%+$10.9M |
| T. Rowe Price Investment Management, Inc. | $105.0M | 1,103,743 | 0.07% | new | NEW |
| BNP PARIBAS FINANCIAL MARKETS | $102.7M | 1,079,015 | 0.04% | 7q | +9773.9%+$101.6M |
| PRICE T ROWE ASSOCIATES INC /MD/ | $79.8M | 838,603 | 0.01% | 8q | +15.3%+$10.6M |
| Avidity Partners Management LP | $72.4M | 760,424 | 11.59% | 8q | -50.0%-$72.4M |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | $62.7M | 658,301 | 1.10% | new | NEW |
| Aberdeen Group plc | $61.6M | 646,943 | 0.09% | 5q | +754.8%+$54.4M |
| UBS Group AG | $60.8M | 639,363 | 0.01% | 7q | +201.2%+$40.6M |
| JPMORGAN CHASE & CO | $60.7M | 655,027 | 0.00% | 7q | +2795.8%+$58.6M |
| WESTFIELD CAPITAL MANAGEMENT CO LP | $60.1M | 631,433 | 0.20% | 2q | +101.7%+$30.3M |
| Pictet Asset Management Holding SA | $58.9M | 619,076 | 0.06% | new | NEW |
| Affinity Asset Advisors, LLC | $56.2M | 590,000 | 2.54% | 8q | +18.1%+$8.6M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $55.4M | 582,409 | 0.00% | 2q | +66.0%+$22.0M |
| Cormorant Asset Management, LP | $50.8M | 533,340 | 2.60% | 4q | HELD |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $41.2M | 433,405 | 0.01% | 7q | +34.6%+$10.6M |
| NORTHERN TRUST CORP | $40.8M | 428,891 | 0.00% | 7q | +43.4%+$12.4M |
| VOYA INVESTMENT MANAGEMENT LLC | $38.2M | 401,149 | 0.03% | 3q | +502.3%+$31.8M |
| LORD, ABBETT & CO. LLC | $37.1M | 390,064 | 0.11% | new | NEW |
| VANGUARD FIDUCIARY TRUST CO | $34.8M | 365,630 | 0.01% | 2q | +42.2%+$10.3M |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $34.7M | 364,102 | 0.01% | new | NEW |
| Synergy Asset Management, LLC | $33.9M | 356,301 | 3.20% | 3q | -25.2%-$11.4M |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $33.8M | 355,003 | 0.05% | 2q | +86.8%+$15.7M |
| BANK OF AMERICA CORP /DE/ | $33.6M | 352,824 | 0.00% | 8q | +252.5%+$24.1M |
| SILVERARC CAPITAL MANAGEMENT, LLC | $33.6M | 352,802 | 3.49% | 2q | +133.8%+$19.2M |
| Candriam S.C.A. | $33.5M | 352,716 | 0.15% | 6q | -14.2%-$5.5M |
| Holocene Advisors, LP | $29.1M | 305,951 | 0.07% | 2q | +64.9%+$11.5M |
| JENNISON ASSOCIATES LLC | $28.5M | 299,257 | 0.02% | 2q | +69.4%+$11.7M |
| Woodline Partners LP | $27.1M | 285,247 | 0.08% | 8q | -50.4%-$27.6M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $26.6M incl. $26.2M options CALL+PUT | 4,588 | 0.00% | 6q | -78.1%-$95.2M |
| BRAIDWELL LP | $26.5M | 278,164 | 0.98% | new | NEW |
| Siren, L.L.C. | $23.8M | 250,000 | 0.48% | new | NEW |
| Nuveen, LLC | $23.7M | 249,267 | 0.01% | 5q | +186.7%+$15.4M |
| EVENTIDE ASSET MANAGEMENT, LLC | $22.8M | 240,000 | 0.31% | new | NEW |
| Blackstone Inc. | $22.6M | 237,108 | 0.06% | new | NEW |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $20.8M | 219,039 | 0.03% | new | NEW |
| SEB Asset Management AB | $18.7M | 196,753 | 0.07% | new | NEW |
| DEUTSCHE BANK AG\ | $18.6M | 195,204 | 0.01% | 5q | +38.7%+$5.2M |
| GREAT POINT PARTNERS LLC | $17.4M | 183,330 | 3.30% | 4q | HELD |
| GOLDMAN SACHS GROUP INC | $17.1M | 179,439 | 0.00% | 6q | -27.3%-$6.4M |
| Sio Capital Management, LLC | $16.9M | 177,118 | 2.79% | 3q | +33.7%+$4.2M |
| Handelsbanken Fonder AB | $15.3M | 160,900 | 0.04% | new | NEW |
| PFM Health Sciences, LP | $15.1M | 158,825 | 1.30% | 2q | -8.7%-$1.4M |
| First Turn Management, LLC | $14.8M | 155,343 | 1.58% | new | NEW |
| ExodusPoint Capital Management, LP | $14.1M | 148,212 | 0.09% | 2q | +46.2%+$4.5M |
| Bank of New York Mellon Corp | $13.4M | 140,870 | 0.00% | 5q | +31.8%+$3.2M |
| Invesco Ltd. | $11.9M | 124,658 | 0.00% | 5q | +28.5%+$2.6M |
| VICTORY CAPITAL MANAGEMENT INC | $11.8M | 124,278 | 0.01% | 2q | +2556.6%+$11.4M |
| WELLINGTON MANAGEMENT GROUP LLP | $11.4M | 119,601 | 0.00% | 4q | -1.3%-$154.6K |
| STEMPOINT CAPITAL LP | $11.1M | 116,461 | 1.91% | new | NEW |
| Parkman Healthcare Partners LLC | $10.8M | 113,188 | 1.10% | new | NEW |
| DIMENSIONAL FUND ADVISORS LP | $10.8M | 113,176 | 0.00% | 2q | HELD |
| Russell Investments Group, Ltd. | $10.7M | 112,943 | 0.01% | 4q | +148.5%+$6.4M |
| Apis Capital Advisors, LLC | $10.7M | 112,000 | 1.04% | new | NEW |
| SEVEN GRAND MANAGERS, LLC | $10.5M | 110,000 | 0.42% | new | NEW |
| KENNEDY CAPITAL MANAGEMENT LLC | $10.2M | 106,863 | 0.18% | 7q | -15.4%-$1.9M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $9.9M | 104,310 | 0.00% | 3q | +517.1%+$8.3M |
| TD Asset Management Inc | $9.8M | 102,944 | 0.01% | 8q | +36.0%+$2.6M |
| Moody Aldrich Partners LLC | $9.7M | 101,411 | 1.73% | 3q | -24.9%-$3.2M |
| Atika Capital Management LLC | $9.5M | 100,000 | 0.63% | 2q | -56.5%-$12.4M |
| TORONTO DOMINION BANK | $8.5M | 89,837 | 0.01% | new | NEW |
| Alyeska Investment Group, L.P. | $8.4M | 87,744 | 0.02% | 3q | -52.5%-$9.2M |
| PRUDENTIAL FINANCIAL INC | $8.2M | 85,895 | 0.01% | 2q | +1322.1%+$7.6M |
| Rhenman & Partners Asset Management AB | $7.6M | 80,000 | 0.72% | new | NEW |
| MORGAN STANLEY | $7.3M | 76,360 | 0.00% | 8q | -56.5%-$9.4M |
| B Group, Inc. | $7.1M | 75,000 | 3.35% | 7q | HELD |
| BARCLAYS PLC | $7.1M | 74,762 | 0.00% | 7q | -12.8%-$1.0M |
| AMERIPRISE FINANCIAL INC | $6.9M | 72,734 | 0.00% | new | NEW |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $6.5M | 68,421 | 0.01% | 8q | -5.7%-$394.2K |
| Fisher Asset Management, LLC | $6.5M | 67,874 | 0.00% | new | NEW |
| Ensign Peak Advisors, Inc | $6.4M | 67,668 | 0.01% | 2q | -14.8%-$1.1M |
| CITIGROUP INC | $6.4M | 67,101 | 0.00% | 8q | +546.0%+$5.4M |
| Secure Asset Management, LLC | $6.3M | 65,899 | 0.88% | 3q | -9.0%-$620.8K |
| Swiss National Bank | $6.0M | 63,000 | 0.00% | 3q | +46.5%+$1.9M |
| ALPS ADVISORS INC | $5.8M | 61,014 | 0.03% | 3q | +54.8%+$2.1M |
| RHUMBLINE ADVISERS | $5.8M | 60,784 | 0.00% | 5q | +31.1%+$1.4M |
| Informed Momentum Co LLC | $5.6M | 59,014 | 0.50% | 2q | -1.6%-$88.7K |
| Atle Fund Management AB | $5.2M | 54,886 | 1.41% | new | NEW |
| WELLS FARGO & COMPANY/MN | $4.9M | 51,924 | 0.00% | 5q | +250.1%+$3.5M |
| Granahan Investment Management, LLC | $4.9M | 51,038 | 0.17% | new | NEW |
| Ghisallo Capital Management LLC | $4.8M | 50,000 | 0.09% | new | NEW |
| Burkehill Global Management, LP | $4.8M | 50,000 | 0.17% | new | NEW |
Showing the largest 100 of 259 reported holders.
What the company announced
Form 8-K filings from the last 120 days, showing only the items worth a reader's attention. Earnings releases, exhibit attachments and general disclosures are filed constantly and are left out. Filed is when the SEC received it; event is the date the company says the thing happened.
| Filed | Event date | What | Source |
|---|---|---|---|
| 2026-08-24 | 2026-08-24 | Directors or officers departed or appointed | filing |
What the insiders did
Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.
Officers and directors
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-09-01 | Klein Lawrence Otto | Chief Executive Officer | Sold | 75,000 | $6.9M ×3 |
| 2026-05-21 | Dambkowski Carl | Director | Sold | 105,000 | $6.2M ×3 |
| 2026-08-14 | Quinlan Paul T | General Counsel | Sold | 52,000 | $5.6M ×6 |
| 2026-10-01 | Klein Lawrence Otto | Chief Executive Officer | Sold | 25,000 | $2.1M ×3 |
| 2026-06-11 | Dambkowski Carl | Director | Sold | 22,417 | $1.6M |
| 2026-08-13 | Agarwal Arjun | Senior Vice President, Finance | Sold | 10,000 | $1.1M ×5 |
| 2026-09-21 | Quinlan Paul T | General Counsel | Sold | 10,000 | $936.4K ×4 |
| 2026-06-12 | Dambkowski Carl | Director | Sold | 12,583 | $882.2K |
| 2026-09-11 | Agarwal Arjun | Senior Vice President, Finance | Sold | 9,459 | $872.4K ×4 |
| 2026-07-13 | Agarwal Arjun | Senior Vice President, Finance | Sold | 9,999 | $846.2K ×4 |
| 2026-10-12 | Agarwal Arjun | Senior Vice President, Finance | Sold | 9,999 | $805.9K ×4 |
| 2026-08-17 | Goncalves Joana | Chief Medical Officer | Sold | 7,000 | $782.9K ×4 |
Ten percent owners and entities
Usually an institution that crossed a reporting threshold, or a company taking a strategic stake, rather than an individual with a view.
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-07-01 | Fairmount Funds Management LLC | Director, 10% owner | Sold | 3,553,410 | $300.0M |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 35 | $21.0M | 252,519 | 10 | 15 | 3 | 0.0% |
| Q2 2026 | 259 | $7.1B | 74,139,147 | 100 | 93 | 46 | 0.5% |
| Q1 2026 | 185 | $2.6B | 52,897,145 | 56 | 62 | 30 | 0.3% |
| Q4 2025 | 145 | $1.6B | 52,851,768 | 39 | 52 | 17 | 0.1% |
| Q3 2025 | 108 | $879.6M | 45,571,933 | 36 | 29 | 22 | 0.4% |
| Q2 2025 | 83 | $386.0M | 34,431,544 | 26 | 24 | 13 | 0.0% |
| Q1 2025 | 72 | $326.1M | 31,776,550 | 18 | 28 | 9 | 0.0% |
| Q4 2024 | 67 | $606.6M | 31,038,326 | 26 | 19 | 8 | 0.0% |
| Q3 2024 | 44 | $604.8M | 24,559,503 | 44 | 0 | 0 | 0.1% |