DaveManuel.com · Institutional Ownership · Who Owns It
SILENCE THERAPEUTICS ADR REP 3 ORD (SLN)
Institutional ownership reported to the SEC as of Q2 2026, across 25 quarters.
73
Reporting holders
$260.9M
Reported value
16.6%
Of shares outstanding
2.7%
Calls
0.2%
Puts
+17
Holder change
Institutions report 23,584,105 shares against 141,740,037 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| Siren, L.L.C. | $36.4M | 3,311,438 | 0.74% | 8q | +13.7%+$4.4M |
| TCG Crossover Management, LLC | $33.3M | 3,033,560 | 0.80% | 16q | HELD |
| Nantahala Capital Management, LLC | $29.6M | 2,693,462 | 0.49% | 10q | +25.5%+$6.0M |
| Redmile Group, LLC | $23.8M | 2,164,777 | 1.60% | 10q | HELD |
| CITADEL ADVISORS LLC | $14.6M | 1,329,625 | 0.00% | 4q | +7.7%+$1.0M |
| Tetragon Partners GP Ltd | $11.7M incl. $3.3M options CALL | 764,256 | 1.84% | 3q | +21.3%+$2.1M |
| Nextech Invest Ltd. | $10.5M | 952,400 | 0.50% | 6q | HELD |
| MILLENNIUM MANAGEMENT LLC | $10.0M | 909,279 | 0.00% | 10q | -15.4%-$1.8M |
| Soleus Capital Management, L.P. | $6.9M | 630,000 | 0.24% | new | NEW |
| Balyasny Asset Management L.P. | $6.7M | 610,980 | 0.01% | new | NEW |
| 5AM Venture Management, LLC | $5.2M | 476,200 | 1.82% | 10q | HELD |
| Caption Management, LLC | $5.1M incl. $3.3M options CALL | 162,476 | 0.02% | new | NEW |
| GREAT POINT PARTNERS LLC | $4.9M | 450,000 | 0.93% | 3q | -55.9%-$6.3M |
| MORGAN STANLEY | $4.4M | 403,172 | 0.00% | 24q | +515.7%+$3.7M |
| JANE STREET GROUP, LLC | $4.3M incl. $202.0K options CALL | 369,151 | 0.00% | 3q | +265.8%+$3.1M |
| AMERIPRISE FINANCIAL INC | $4.1M | 370,052 | 0.00% | new | NEW |
| ADAR1 Capital Management, LLC | $3.7M | 338,373 | 0.17% | 11q | +96.5%+$1.8M |
| SummitTX Capital, L.P. | $3.6M | 326,648 | 0.09% | new | NEW |
| Schonfeld Strategic Advisors LLC | $3.0M | 269,348 | 0.01% | new | NEW |
| UBS Group AG | $2.7M | 243,152 | 0.00% | 19q | -1.5%-$41.6K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2.6M incl. $540.2K options CALL+PUT | 184,519 | 0.00% | 3q | +60.1%+$962.9K |
| Ishara Investments LP | $2.4M | 55,350 | 1.79% | 3q | -60.6%-$3.7M |
| BlackRock, Inc. | $2.4M | 219,917 | 0.00% | 7q | +7.4%+$166.2K |
| BANK OF MONTREAL /CAN/ | $2.2M | 201,734 | 0.00% | 8q | -0.6%-$12.8K |
| BOOTHBAY FUND MANAGEMENT, LLC | $2.2M | 198,347 | 0.03% | 10q | -5.1%-$117.9K |
| Propel Bio Management, LLC | $2.1M | 191,733 | 1.10% | new | NEW |
| FRED ALGER MANAGEMENT, LLC | $1.9M | 177,000 | 0.01% | new | NEW |
| Ikarian Capital, LLC | $1.8M | 830,784 | 0.20% | 5q | -4.0%-$77.0K |
| Qube Research & Technologies Ltd | $1.8M | 163,945 | 0.00% | 3q | +56.8%+$652.1K |
| BNP PARIBAS FINANCIAL MARKETS | $1.7M | 158,950 | 0.00% | 7q | +7.6%+$123.9K |
| GOLDMAN SACHS GROUP INC | $1.7M | 155,929 | 0.00% | 4q | +196.9%+$1.1M |
| TWO SIGMA INVESTMENTS, LP | $1.3M | 121,004 | 0.00% | 10q | +646.8%+$1.2M |
| HSBC HOLDINGS PLC | $1.3M | 122,834 | 0.00% | 19q | HELD |
| Quadrature Capital Ltd | $1.3M | 118,129 | 0.01% | new | NEW |
| Squarepoint Ops LLC | $1.3M | 115,918 | 0.00% | 2q | +29.6%+$290.4K |
| XTX Topco Ltd | $1.2M | 107,579 | 0.02% | 3q | +1.5%+$17.3K |
| M28 Capital Management LP | $1.1M | 101,203 | 2.36% | 15q | HELD |
| MARSHALL WACE, LLP | $791.0K | 72,039 | 0.00% | 10q | -57.5%-$1.1M |
| Birchview Capital, LP | $782.0K | 71,218 | 0.37% | new | NEW |
| Seven Fleet Capital Management LP | $660.0K | 60,107 | 0.11% | 3q | -61.7%-$1.1M |
| HRT FINANCIAL LP | $337.0K | 30,748 | 0.00% | 2q | +156.4%+$205.5K |
| GEODE CAPITAL MANAGEMENT, LLC | $324.3K | 29,538 | 0.00% | 16q | HELD |
| Virtu Financial LLC | $282.0K | 25,641 | 0.01% | new | NEW |
| BANK OF AMERICA CORP /DE/ | $277.6K | 25,280 | 0.00% | 14q | -15.1%-$49.3K |
| Trexquant Investment LP | $261.8K | 23,842 | 0.00% | new | NEW |
| Verdad Advisers, LP | $224.0K | 20,400 | 0.21% | new | NEW |
| Scientech Research LLC | $210.1K | 19,133 | 0.17% | new | NEW |
| RENAISSANCE TECHNOLOGIES LLC | $185.9K | 16,930 | 0.00% | new | NEW |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | $179.3K | 16,334 | 0.04% | new | NEW |
| Persistent Asset Partners Ltd | $166.6K | 15,170 | 0.05% | new | NEW |
| RAYMOND JAMES FINANCIAL INC | $164.7K | 15,000 | 0.00% | 3q | -40.0%-$109.8K |
| RHUMBLINE ADVISERS | $151.7K | 13,815 | 0.00% | 12q | -0.9%-$1.3K |
| SIMPLEX TRADING, LLC | $148.2K CALL+PUT | options only | 0.00% | 5q | OPTIONS |
| CITIGROUP INC | $145.1K | 13,217 | 0.00% | 19q | +620.3%+$125.0K |
| AXQ CAPITAL, LP | $138.0K | 12,566 | 0.02% | new | NEW |
| SG Americas Securities, LLC | $132.0K | 12,056 | 0.00% | 11q | -95.8%-$3.0M |
| ACADIAN ASSET MANAGEMENT LLC | $129.0K | 11,836 | 0.00% | 2q | +145.7%+$76.5K |
| GAMMA Investing LLC | $121.5K | 11,063 | 0.00% | 11q | +18.1%+$18.6K |
| CenterBook Partners LP | $114.4K | 10,416 | 0.01% | new | NEW |
| China Universal Asset Management Co., Ltd. | $82.1K | 7,475 | 0.00% | 7q | -10.3%-$9.4K |
| JPMORGAN CHASE & CO | $41.7K | 3,863 | 0.00% | 7q | -49.4%-$40.7K |
| BARCLAYS PLC | $37.5K | 3,418 | 0.00% | 10q | +16.4%+$5.3K |
| JONES FINANCIAL COMPANIES LLLP | $25.4K | 2,500 | 0.00% | 6q | HELD |
| Mirae Asset Global Investments Co., Ltd. | $23.1K | 2,101 | 0.00% | 7q | -14.2%-$3.8K |
| Tower Research Capital LLC (TRC) | $18.0K | 1,639 | 0.00% | 7q | -29.1%-$7.4K |
| Parallel Advisors, LLC | $14.3K | 1,300 | 0.00% | 6q | HELD |
| Rialto Wealth Management, LLC | $11.2K | 1,021 | 0.00% | new | NEW |
| GF FUND MANAGEMENT CO. LTD. | $10.7K | 975 | 0.00% | 7q | -6.9% |
| Steward Partners Investment Advisory, LLC | $1.1K | 100 | 0.00% | 19q | HELD |
| Rockefeller Capital Management L.P. | $494 | 45 | 0.00% | 4q | HELD |
| Caitong International Asset Management Co., Ltd | $450 | 41 | 0.00% | 2q | +1266.7% |
| SBI Securities Co., Ltd. | $307 | 28 | 0.00% | 7q | HELD |
| ROYAL BANK OF CANADA | $0 | 26 | 0.00% | 2q | +62.5% |
What the company announced
Form 8-K filings from the last 120 days, showing only the items worth a reader's attention. Earnings releases, exhibit attachments and general disclosures are filed constantly and are left out. Filed is when the SEC received it; event is the date the company says the thing happened.
| Filed | Event date | What | Source |
|---|---|---|---|
| 2026-10-19 | 2026-10-18 | Material agreement entered | filing |
| 2026-08-12 | 2026-08-10 | Material agreement entered | filing |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 10 | $745.5K | 68,375 | 4 | 6 | 0 | 0.0% |
| Q2 2026 | 73 | $260.9M | 23,584,105 | 20 | 22 | 18 | 2.9% |
| Q1 2026 | 56 | $102.4M | 19,909,495 | 6 | 24 | 11 | 0.3% |
| Q4 2025 | 57 | $107.4M | 18,262,885 | 13 | 14 | 16 | 0.3% |
| Q3 2025 | 54 | $96.5M | 19,712,203 | 6 | 14 | 12 | 0.0% |
| Q2 2025 | 55 | $108.2M | 19,762,081 | 11 | 9 | 18 | 0.1% |
| Q1 2025 | 58 | $60.6M | 21,916,214 | 5 | 16 | 24 | 0.0% |
| Q4 2024 | 65 | $168.2M | 24,817,325 | 14 | 24 | 12 | 0.0% |
| Q3 2024 | 70 | $493.2M | 28,197,464 | 13 | 24 | 15 | 0.0% |
| Q2 2024 | 71 | $534.1M | 28,909,685 | 12 | 22 | 20 | 0.0% |
| Q1 2024 | 64 | $598.7M | 28,218,821 | 32 | 17 | 10 | 0.0% |
| Q4 2023 | 34 | $345.0M | 20,602,842 | 6 | 9 | 6 | 0.0% |
| Q3 2023 | 28 | $187.6M | 19,721,299 | 4 | 4 | 7 | 0.0% |
| Q2 2023 | 29 | $101.8M | 19,229,837 | 2 | 12 | 5 | 0.0% |
| Q1 2023 | 29 | $110.2M | 18,398,088 | 4 | 8 | 6 | 0.0% |
| Q4 2022 | 27 | $275.7M | 18,637,187 | 2 | 7 | 4 | 0.0% |
| Q3 2022 | 28 | $189.0M | 19,218,869 | 7 | 8 | 5 | 0.0% |
| Q2 2022 | 24 | $123.6M | 10,979,989 | 3 | 5 | 6 | 0.0% |
| Q1 2022 | 25 | $230.8M | 12,844,977 | 6 | 3 | 5 | 0.0% |
| Q4 2021 | 21 | $246.6M | 10,341,285 | 12 | 6 | 0 | 0.0% |
| Q3 2021 | 7 | $39.4M | 1,955,799 | 1 | 2 | 2 | 0.0% |
| Q2 2021 | 6 | $56.4M | 2,261,433 | 0 | 0 | 3 | 0.0% |
| Q1 2021 | 6 | $55.9M | 2,547,036 | 4 | 2 | 0 | 0.0% |
| Q4 2020 | 3 | $10.2M | 542,093 | 1 | 0 | 0 | 0.0% |
| Q3 2020 | 2 | $8.1M | 542,000 | 2 | 0 | 0 | 0.0% |