DaveManuel.com · Institutional Ownership · Who Owns It
CARIS LIFE SCIENCES INC (CAI)
Institutional ownership reported to the SEC as of Q2 2026, across 18 quarters.
249
Reporting holders
$2.8B
Reported value
54.6%
Of shares outstanding
0.4%
Calls
0.2%
Puts
+46
Holder change
Institutions report 154,405,897 shares against 282,595,186 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| FMR LLC | $551.1M | 30,923,878 | 0.02% | 5q | HELD |
| J. H. Whitney Equity Partners VI, LLC | $200.6M | 11,256,615 | 100.00% | 3q | -38.3%-$124.7M |
| COATUE MANAGEMENT LLC | $175.0M | 9,819,992 | 0.36% | 5q | HELD |
| BRAIDWELL LP | $147.1M | 8,256,032 | 5.44% | 5q | +3.1%+$4.4M |
| Sixth Street Partners Management Company, L.P. | $130.6M | 7,327,041 | 22.54% | 5q | -49.1%-$125.8M |
| PointState Capital LP | $121.7M | 6,828,835 | 1.56% | 5q | -7.2%-$9.5M |
| JPMORGAN CHASE & CO | $120.2M | 6,558,514 | 0.01% | 5q | +89.5%+$56.8M |
| BlackRock, Inc. | $98.7M | 5,536,798 | 0.00% | 5q | +14.0%+$12.1M |
| T. Rowe Price Investment Management, Inc. | $90.5M | 5,079,141 | 0.06% | 5q | -9.1%-$9.1M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $86.3M | 4,844,431 | 0.00% | 2q | +28.9%+$19.4M |
| VANGUARD CAPITAL MANAGEMENT LLC | $76.3M | 4,280,238 | 0.00% | 2q | +28.6%+$17.0M |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $70.5M | 3,958,531 | 0.26% | 3q | +72.9%+$29.7M |
| NEUBERGER BERMAN GROUP LLC | $64.0M | 3,590,963 | 0.04% | 5q | HELD |
| ORBIMED ADVISORS LLC | $50.0M | 2,806,811 | 0.93% | 5q | HELD |
| BNP PARIBAS FINANCIAL MARKETS | $42.2M | 2,370,268 | 0.01% | 4q | +46.8%+$13.5M |
| MILLENNIUM MANAGEMENT LLC | $39.3M | 2,202,647 | 0.01% | 5q | +44.2%+$12.0M |
| MAK CAPITAL ONE LLC | $34.5M | 1,937,229 | 4.84% | new | NEW |
| MORGAN STANLEY | $34.5M | 1,935,531 | 0.00% | 5q | +79.3%+$15.3M |
| Duquesne Family Office LLC | $33.8M | 1,894,450 | 0.65% | 2q | HELD |
| Clearbridge Investments, LLC | $28.4M | 1,595,877 | 0.02% | 5q | +2.8%+$785.9K |
| FIL Ltd | $27.6M | 1,548,918 | 0.02% | 5q | HELD |
| UBS Group AG | $25.4M | 1,423,371 | 0.00% | 4q | -48.2%-$23.6M |
| HRT FINANCIAL LP | $25.3M | 1,418,392 | 0.05% | new | NEW |
| CANADA PENSION PLAN INVESTMENT BOARD | $24.5M | 1,374,952 | 0.01% | 5q | +3.9%+$930.2K |
| STATE STREET CORP | $21.7M | 1,217,548 | 0.00% | 4q | +23.6%+$4.2M |
| Amundi | $21.7M | 1,218,364 | 0.01% | 2q | +5709.5%+$21.3M |
| Capital World Investors | $21.6M | 1,213,272 | 0.00% | 2q | +2.8%+$589.8K |
| PRICE T ROWE ASSOCIATES INC /MD/ | $21.5M | 1,205,390 | 0.00% | 5q | -72.4%-$56.4M |
| BANK OF AMERICA CORP /DE/ | $21.4M | 1,200,590 | 0.00% | 5q | +129.4%+$12.1M |
| Champlain Investment Partners, LLC | $18.7M | 1,048,862 | 0.48% | 3q | -13.2%-$2.8M |
| GEODE CAPITAL MANAGEMENT, LLC | $18.6M | 1,044,657 | 0.00% | 5q | +34.2%+$4.7M |
| GOLDMAN SACHS GROUP INC | $17.0M | 951,942 | 0.00% | 5q | +132.0%+$9.7M |
| ZEVENBERGEN CAPITAL INVESTMENTS LLC | $14.3M | 802,083 | 0.33% | 3q | +31.4%+$3.4M |
| SEI INVESTMENTS CO | $13.6M | 762,659 | 0.01% | 3q | +27.4%+$2.9M |
| Trexquant Investment LP | $13.0M | 727,944 | 0.08% | 3q | +48.4%+$4.2M |
| Woodline Partners LP | $12.9M | 723,163 | 0.04% | 5q | HELD |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $11.7M | 655,644 | 0.01% | 2q | +211.3%+$7.9M |
| Nuveen, LLC | $10.8M | 604,416 | 0.00% | 4q | -8.9%-$1.1M |
| AMERIPRISE FINANCIAL INC | $10.2M | 572,784 | 0.00% | 5q | +40.4%+$2.9M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $10.2M incl. $6.5M options CALL+PUT | 204,432 | 0.00% | 5q | +285.2%+$7.5M |
| RENAISSANCE TECHNOLOGIES LLC | $10.1M | 568,000 | 0.01% | 4q | +26.3%+$2.1M |
| Rock Springs Capital Management LP | $8.7M | 487,500 | 0.42% | 5q | -13.4%-$1.3M |
| Quantinno Capital Management LP | $7.9M | 441,672 | 0.01% | 4q | +213.4%+$5.4M |
| Walleye Capital LLC | $7.6M | 424,407 | 0.03% | new | NEW |
| CITADEL ADVISORS LLC | $7.0M incl. $1.7M options CALL+PUT | 297,855 | 0.00% | 5q | +282.8%+$5.2M |
| Squarepoint Ops LLC | $6.8M | 380,927 | 0.01% | new | NEW |
| TD Asset Management Inc | $6.8M | 379,388 | 0.01% | 5q | -43.4%-$5.2M |
| Bank of New York Mellon Corp | $5.5M | 308,407 | 0.00% | 4q | +33.1%+$1.4M |
| MENLO ADVISORS LLC | $5.4M | 300,518 | 2.35% | new | NEW |
| FEDERATED HERMES, INC. | $5.1M | 285,598 | 0.01% | 3q | +19.4%+$827.7K |
| PICTON MAHONEY ASSET MANAGEMENT | $4.7M | 264,064 | 0.03% | 4q | -5.3%-$265.7K |
| NORTHERN TRUST CORP | $4.6M | 258,787 | 0.00% | 4q | +48.7%+$1.5M |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $4.4M | 247,605 | 0.01% | new | NEW |
| Qube Research & Technologies Ltd | $4.0M | 226,878 | 0.00% | 5q | +21.0%+$702.1K |
| MARSHALL WACE, LLP | $4.0M | 222,717 | 0.00% | new | NEW |
| JANE STREET GROUP, LLC | $3.9M CALL+PUT | options only | 0.00% | 4q | OPTIONS |
| Maxi Investments CY Ltd | $3.8M | 210,670 | 0.76% | new | NEW |
| D. E. Shaw & Co., Inc. | $3.6M | 204,818 | 0.00% | 2q | +58.1%+$1.3M |
| WORLDQUANT MILLENNIUM ADVISORS LLC | $3.6M | 204,152 | 0.01% | 4q | +4.8%+$168.3K |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $3.2M | 182,345 | 0.00% | 4q | +3545.4%+$3.2M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $3.1M | 173,010 | 0.00% | 3q | +470.0%+$2.5M |
| Militia Capital Management LLC | $3.0M | 166,600 | 0.09% | new | NEW |
| SG Americas Securities, LLC | $2.7M | 152,236 | 0.00% | new | NEW |
| XTX Topco Ltd | $2.4M | 136,488 | 0.03% | 2q | +73.9%+$1.0M |
| VANGUARD FIDUCIARY TRUST CO | $2.4M | 132,479 | 0.00% | 2q | +37.2%+$639.7K |
| CastleKnight Management LP | $2.4M | 132,236 | 0.03% | 5q | +222.2%+$1.6M |
| Invesco Ltd. | $2.4M | 132,103 | 0.00% | 5q | -89.2%-$19.4M |
| NATIXIS | $2.2M | 124,716 | 0.01% | 2q | +136.3%+$1.3M |
| STATE OF WISCONSIN INVESTMENT BOARD | $2.2M | 123,129 | 0.00% | 5q | -9.7%-$235.3K |
| Cambridge Investment Research Advisors, Inc. | $2.1M | 119,746 | 0.00% | new | NEW |
| CITIGROUP INC | $2.0M | 111,236 | 0.00% | 5q | +44.1%+$606.9K |
| Caption Management, LLC | $2.0M incl. $2.0M options CALL+PUT | 19 | 0.01% | 4q | -99.9%-$3.4B |
| IMC-Chicago, LLC | $1.8M incl. $1.4M options CALL+PUT | 23,148 | 0.00% | 3q | +79.2%+$817.0K |
| ROYAL BANK OF CANADA | $1.8M | 102,044 | 0.00% | 5q | +447.1%+$1.5M |
| TUDOR INVESTMENT CORP ET AL | $1.8M | 100,327 | 0.00% | 5q | HELD |
| SALEM INVESTMENT COUNSELORS INC | $1.8M | 100,000 | 0.04% | new | NEW |
| Ghisallo Capital Management LLC | $1.8M | 100,000 | 0.03% | 5q | -60.0%-$2.7M |
| RHUMBLINE ADVISERS | $1.8M | 98,849 | 0.00% | 4q | +32.5%+$431.7K |
| RAYMOND JAMES FINANCIAL INC | $1.8M | 98,595 | 0.00% | 5q | +9.3%+$149.0K |
| Smartleaf Asset Management LLC | $1.7M | 94,051 | 0.06% | 2q | HELD |
| Gotham Asset Management, LLC | $1.6M | 89,535 | 0.00% | 4q | -88.0%-$11.7M |
| Mitsubishi UFJ Asset Management Co., Ltd. | $1.5M | 85,600 | 0.00% | new | NEW |
| Pathstone Holdings, LLC | $1.5M | 82,782 | 0.00% | new | NEW |
| LAZARD ASSET MANAGEMENT LLC | $1.5M | 81,736 | 0.00% | 5q | -73.3%-$4.0M |
| ALLIANCEBERNSTEIN L.P. | $1.4M | 81,021 | 0.00% | 5q | +42.0%+$428.1K |
| Exome Asset Management LLC | $1.4M | 78,180 | 0.86% | new | NEW |
| Creative Planning | $1.4M | 77,456 | 0.00% | 3q | -0.7%-$9.7K |
| ENVESTNET ASSET MANAGEMENT INC | $1.3M | 71,695 | 0.00% | 3q | +33.7%+$322.3K |
| Jain Global LLC | $1.2M | 68,222 | 0.00% | new | NEW |
| MOORE CAPITAL MANAGEMENT, LP | $1.1M | 63,895 | 0.02% | new | NEW |
| JONES FINANCIAL COMPANIES LLLP | $1.1M | 61,237 | 0.00% | 4q | +398.0%+$905.4K |
| Renaissance Capital LLC | $1.1M | 62,887 | 0.62% | 4q | +44.6%+$345.8K |
| NEW YORK STATE COMMON RETIREMENT FUND | $1.1M | 61,300 | 0.00% | 3q | +34.1%+$278.0K |
| AQR CAPITAL MANAGEMENT LLC | $1.1M | 59,103 | 0.00% | 2q | +103.8%+$536.5K |
| Sumitomo Mitsui Trust Group, Inc. | $978.1K | 54,890 | 0.00% | 5q | -3.3%-$33.0K |
| Police & Firemen's Retirement System of New Jersey | $963.3K | 54,057 | 0.01% | 4q | +36.9%+$259.5K |
| Treasurer of the State of North Carolina | $936.0K | 52,515 | 0.00% | 4q | +34.6%+$240.8K |
| LPL Financial LLC | $917.8K | 51,502 | 0.00% | 5q | +22.5%+$168.6K |
| GROUP ONE TRADING LLC | $883.8K incl. $662.9K options CALL+PUT | 12,397 | 0.00% | 4q | -31.8%-$411.8K |
| NATIXIS ADVISORS, LLC | $883.0K | 49,587 | 0.00% | 2q | +260.4%+$638.0K |
Showing the largest 100 of 249 reported holders.
What the insiders did
Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.
Officers and directors
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-09-17 | Brille Brian J | See Remarks | Sold | 400,000 | $12.1M |
| 2026-09-03 | Spetzler David Baxley | President | Sold | 478,000 | $11.9M ×2 |
| 2026-09-04 | Spetzler David Baxley | President | Sold | 119,212 | $3.0M |
| 2026-05-15 | HALBERT JON | Director | Bought | 68,000 | $990.1K |
| 2026-05-11 | Vacirca Jeff L | Director | Bought | 31,050 | $501.4K |
| 2026-09-22 | Denton John Russel | See Remarks | Sold | 7,500 | $238.6K |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 75 | $68.9M | 2,270,760 | 31 | 18 | 15 | 0.0% |
| Q2 2026 | 249 | $2.8B | 154,405,897 | 69 | 102 | 48 | 0.6% |
| Q1 2026 | 203 | $2.8B | 156,723,055 | 51 | 87 | 39 | 0.4% |
| Q4 2025 | 187 | $4.0B | 149,044,304 | 71 | 63 | 31 | 0.5% |
| Q3 2025 | 143 | $3.5B | 114,261,995 | 57 | 46 | 19 | 0.4% |
| Q2 2025 | 118 | $2.9B | 109,326,693 | 119 | 0 | 0 | 0.1% |
| Q3 2021 | 125 | $1.1B | 19,469,486 | 21 | 38 | 44 | 0.5% |
| Q2 2021 | 141 | $1.6B | 27,385,545 | 38 | 33 | 52 | 2.3% |
| Q1 2021 | 140 | $892.4M | 19,511,664 | 38 | 43 | 41 | 0.5% |
| Q4 2020 | 114 | $687.1M | 21,936,557 | 28 | 40 | 26 | 0.3% |
| Q3 2020 | 88 | $558.5M | 20,268,596 | 14 | 22 | 31 | 0.1% |
| Q2 2020 | 81 | $338.2M | 20,280,576 | 10 | 26 | 25 | 0.1% |
| Q1 2020 | 81 | $403.9M | 28,510,006 | 9 | 21 | 30 | 0.2% |
| Q4 2019 | 89 | $614.5M | 21,144,961 | 13 | 27 | 29 | 0.3% |
| Q3 2019 | 89 | $458.6M | 21,006,895 | 13 | 32 | 29 | 0.3% |
| Q2 2019 | 96 | $535.1M | 21,326,971 | 12 | 34 | 32 | 1.1% |
| Q1 2019 | 100 | $531.7M | 21,967,127 | 13 | 32 | 33 | 4.1% |
| Q4 2018 | 99 | $518.6M | 21,854,392 | 3 | 2 | 4 | 2.1% |