DaveManuel.com · Institutional Ownership · Who Owns It
APOGEE THERAPEUTICS INC (APGE)
Institutional ownership reported to the SEC as of Q2 2026, across 13 quarters.
293
Reporting holders
$9.1B
Reported value
0.4%
Calls
1.8%
Puts
+65
Holder change
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| Venrock Adviser, LLC | $1.1B | 8,493,321 | 34.18% | 12q | HELD |
| BlackRock, Inc. | $730.9M | 5,507,032 | 0.01% | 8q | +34.8%+$188.7M |
| HBK INVESTMENTS L P | $378.3M | 2,850,000 | 3.67% | new | NEW |
| VANGUARD CAPITAL MANAGEMENT LLC | $341.4M | 2,572,119 | 0.01% | 2q | +2.8%+$9.3M |
| FMR LLC | $330.9M | 2,493,137 | 0.01% | 12q | -73.1%-$898.5M |
| STATE STREET CORP | $305.0M | 2,297,743 | 0.01% | 12q | +6.2%+$17.9M |
| Balyasny Asset Management L.P. | $287.4M incl. $66.4M options PUT | 1,665,102 | 0.36% | 2q | +279.6%+$211.7M |
| Driehaus Capital Management LLC | $231.0M | 1,740,101 | 1.34% | 12q | -9.4%-$24.0M |
| GOLDMAN SACHS GROUP INC | $224.8M | 1,693,341 | 0.02% | 12q | +159.5%+$138.1M |
| GLAZER CAPITAL, LLC | $217.8M | 1,641,042 | 5.36% | new | NEW |
| Paradigm Biocapital Advisors LP | $209.2M | 1,576,385 | 3.92% | 10q | +16.9%+$30.3M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $202.9M | 1,528,750 | 0.01% | 2q | +285.7%+$150.3M |
| MILLENNIUM MANAGEMENT LLC | $199.3M incl. $1.3M options CALL | 1,491,404 | 0.07% | 11q | +1510.7%+$186.9M |
| Pentwater Capital Management LP | $189.1M | 1,425,000 | 1.16% | new | NEW |
| MORGAN STANLEY | $188.7M | 1,421,681 | 0.01% | 12q | +138.9%+$109.7M |
| GEODE CAPITAL MANAGEMENT, LLC | $174.6M | 1,314,868 | 0.01% | 12q | +8.0%+$13.0M |
| PERCEPTIVE ADVISORS LLC | $173.6M | 1,308,113 | 2.61% | 12q | -15.1%-$30.8M |
| Jupiter Topco LLC | $158.4M | 1,193,626 | 0.06% | new | FIRST |
| BANK OF AMERICA CORP /DE/ | $149.5M | 1,126,139 | 0.01% | 12q | +25.0%+$29.9M |
| Affinity Asset Advisors, LLC | $131.0M | 987,000 | 5.92% | 12q | -23.2%-$39.5M |
| MERCER GLOBAL ADVISORS INC /ADV | $124.9M | 941,283 | 0.15% | 7q | +13.2%+$14.6M |
| First Light Asset Management, LLC | $123.5M | 930,289 | 7.50% | 3q | +61.3%+$46.9M |
| T. Rowe Price Investment Management, Inc. | $101.2M | 762,183 | 0.07% | 5q | -92.6%-$1.3B |
| Kryger Capital LLC | $98.6M | 742,555 | 5.62% | new | NEW |
| Qube Research & Technologies Ltd | $87.6M | 659,678 | 0.08% | new | NEW |
| First Trust Capital Management L.P. | $83.0M | 625,182 | 4.83% | new | NEW |
| Remedium Capital Partners, LLC | $77.9M | 586,691 | 17.24% | 3q | +0.5%+$411.5K |
| SOROS FUND MANAGEMENT LLC | $74.9M | 564,500 | 0.92% | new | NEW |
| WELLINGTON MANAGEMENT GROUP LLP | $74.9M | 564,326 | 0.01% | 12q | -87.1%-$505.9M |
| ALLIANCEBERNSTEIN L.P. | $65.2M | 775,058 | 0.02% | 11q | -21.7%-$18.1M |
| Woodline Partners LP | $61.7M | 464,622 | 0.19% | 12q | +77.9%+$27.0M |
| WHITEBOX ADVISORS LLC | $59.7M | 450,001 | 0.78% | new | NEW |
| NORTHERN TRUST CORP | $59.1M | 445,154 | 0.01% | 12q | +13.9%+$7.2M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $58.9M | 443,658 | 0.01% | 12q | +5.5%+$3.0M |
| AQR Arbitrage LLC | $57.1M | 429,900 | 0.81% | new | NEW |
| Magnetar Financial LLC | $53.0M | 399,123 | 0.48% | new | NEW |
| Man Group plc | $52.7M | 397,000 | 0.08% | 3q | +849.4%+$47.1M |
| VANGUARD FIDUCIARY TRUST CO | $52.2M | 393,180 | 0.01% | 2q | +6.6%+$3.2M |
| Opaleye Management Inc. | $51.8M | 390,000 | 4.69% | 4q | HELD |
| JPMORGAN CHASE & CO | $49.9M incl. $2.0M options PUT | 359,250 | 0.00% | 12q | -67.6%-$104.3M |
| PICTON MAHONEY ASSET MANAGEMENT | $48.4M incl. $26.5M options PUT | 165,000 | 0.36% | new | NEW |
| TIG Advisors, LLC | $48.3M | 364,250 | 2.14% | new | NEW |
| FRANKLIN RESOURCES INC | $48.2M | 363,379 | 0.01% | 12q | -10.4%-$5.6M |
| Cinctive Capital Management LP | $46.5M | 350,165 | 1.71% | new | NEW |
| LOOMIS SAYLES & CO L P | $45.0M | 338,664 | 0.06% | 3q | -6.6%-$3.2M |
| Polar Asset Management Partners Inc. | $42.8M incl. $26.5K options PUT | 322,467 | 0.71% | new | NEW |
| FRONTIER CAPITAL MANAGEMENT CO LLC | $40.3M | 303,739 | 0.38% | 8q | -71.5%-$101.0M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $40.3M incl. $36.7M options CALL+PUT | 27,256 | 0.00% | 11q | +69.3%+$16.5M |
| NEXPOINT ASSET MANAGEMENT, L.P. | $39.8M | 299,940 | 2.66% | new | NEW |
| Fairmount Funds Management LLC | $39.6M | 298,647 | 2.62% | 12q | HELD |
| Squarepoint Ops LLC | $38.6M | 290,713 | 0.04% | 2q | +658.1%+$33.5M |
| CITIGROUP INC | $38.4M | 289,464 | 0.01% | 11q | +1969.4%+$36.6M |
| Slotnik Capital, LLC | $34.6M | 260,740 | 8.94% | new | NEW |
| EVENTIDE ASSET MANAGEMENT, LLC | $34.5M | 260,000 | 0.46% | 3q | -53.4%-$39.5M |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $33.2M | 250,000 | 0.05% | 7q | HELD |
| D. E. Shaw & Co., Inc. | $32.7M | 246,086 | 0.02% | 9q | +318.3%+$24.9M |
| PRICE T ROWE ASSOCIATES INC /MD/ | $31.5M | 237,210 | 0.00% | 12q | -79.2%-$120.2M |
| BNP PARIBAS FINANCIAL MARKETS | $27.9M | 210,212 | 0.01% | 7q | -4.5%-$1.3M |
| Absolute Gestao de Investimentos Ltda. | $27.2M | 205,000 | 2.74% | new | NEW |
| UBS Group AG | $26.8M | 201,831 | 0.00% | 10q | -82.4%-$125.1M |
| MUFG Securities EMEA plc | $24.0M | 180,500 | 0.25% | new | NEW |
| Allianz Asset Management GmbH | $23.5M | 177,000 | 0.02% | 2q | +6980.0%+$23.2M |
| Verition Fund Management LLC | $21.4M incl. $265.5K options CALL | 159,256 | 0.11% | new | NEW |
| HIGHBRIDGE CAPITAL MANAGEMENT LLC | $20.7M | 155,857 | 0.50% | new | NEW |
| Sagefield Capital LP | $20.6M | 155,135 | 1.53% | new | NEW |
| Bank of New York Mellon Corp | $20.3M | 152,815 | 0.00% | 12q | +20.6%+$3.5M |
| RENAISSANCE TECHNOLOGIES LLC | $19.5M | 146,800 | 0.03% | new | NEW |
| First Turn Management, LLC | $18.4M | 138,822 | 1.97% | 7q | -73.0%-$49.8M |
| Grantham, Mayo, Van Otterloo & Co. LLC | $18.2M | 137,395 | 0.04% | new | NEW |
| TUDOR INVESTMENT CORP ET AL | $18.1M incl. $13.4M options PUT | 35,734 | 0.03% | new | NEW |
| Nuveen, LLC | $17.5M | 131,634 | 0.00% | 6q | +2.7%+$467.1K |
| GABELLI FUNDS LLC | $16.9M | 127,281 | 0.11% | new | NEW |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $16.1M | 121,258 | 0.02% | 7q | -5.3%-$896.9K |
| Twin Securities, Inc. | $15.9M | 120,000 | 7.13% | new | NEW |
| CAPSTONE INVESTMENT ADVISORS, LLC | $15.9M | 120,000 | 0.03% | new | NEW |
| Melqart Asset Management (UK) Ltd | $15.6M | 117,249 | 1.48% | new | NEW |
| Caption Management, LLC | $15.4M PUT | options only | 0.07% | 2q | OPTIONS |
| Maven Securities LTD | $15.3M | 115,018 | 0.30% | 2q | +360.1%+$11.9M |
| WATER ISLAND CAPITAL LLC | $14.9M incl. $2.3M options PUT | 94,900 | 1.39% | new | NEW |
| SEVEN GRAND MANAGERS, LLC | $13.3M | 100,000 | 0.53% | 3q | HELD |
| DEUTSCHE BANK AG\ | $13.1M | 98,979 | 0.00% | 12q | +8.3%+$1.0M |
| TWO SIGMA INVESTMENTS, LP | $12.6M | 94,759 | 0.01% | 11q | -66.3%-$24.8M |
| VICTORY CAPITAL MANAGEMENT INC | $11.7M | 87,953 | 0.01% | 12q | -7.6%-$953.5K |
| ExodusPoint Capital Management, LP | $11.7M incl. $11.6M options CALL | 348 | 0.08% | new | NEW |
| Handelsbanken Fonder AB | $11.5M | 86,300 | 0.03% | 9q | +309.0%+$8.7M |
| Groupe la Francaise | $11.2M | 84,072 | 0.13% | new | NEW |
| GABELLI & Co INVESTMENT ADVISERS, INC. | $10.8M | 81,645 | 1.58% | new | NEW |
| GARDNER LEWIS ASSET MANAGEMENT L P | $10.6M | 80,000 | 2.37% | new | NEW |
| Candriam S.C.A. | $10.6M | 79,684 | 0.05% | 4q | -64.4%-$19.1M |
| HARVEST MANAGEMENT LLC | $10.5M | 79,000 | 4.12% | new | NEW |
| MARSHALL WACE, LLP | $10.3M | 77,475 | 0.01% | 9q | -3.4%-$361.8K |
| Swiss National Bank | $10.2M | 76,700 | 0.01% | 11q | +1.5%+$146.0K |
| PRUDENTIAL FINANCIAL INC | $10.2M | 76,620 | 0.01% | 10q | +19.9%+$1.7M |
| WCM INVESTMENT MANAGEMENT, LLC | $10.1M | 75,974 | 0.02% | 2q | HELD |
| Alberta Investment Management Corp | $10.0M | 75,000 | 0.06% | new | NEW |
| Chicago Capital Management, LLC | $9.8M | 97,100 | 8.73% | new | NEW |
| Westchester Capital Management, LLC | $9.7M | 72,962 | 0.47% | new | NEW |
| Boxer Capital Management, LLC | $9.3M | 70,000 | 0.70% | 4q | HELD |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $8.8M | 66,433 | 0.00% | 9q | +17.9%+$1.3M |
| KENNEDY CAPITAL MANAGEMENT LLC | $8.5M | 63,981 | 0.15% | 10q | -47.8%-$7.8M |
Showing the largest 100 of 293 reported holders.
What the insiders did
Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.
Officers and directors
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-06-22 | HENDERSON MICHAEL THOMAS | Chief Executive Officer | Sold | 80,000 | $10.6M |
| 2026-06-22 | Dambkowski Carl | Chief Medical Officer | Sold | 26,400 | $3.5M |
| 2026-07-08 | HENDERSON MICHAEL THOMAS | Chief Executive Officer | Sold | 20,000 | $2.7M |
| 2026-06-10 | HENDERSON MICHAEL THOMAS | Chief Executive Officer | Sold | 20,000 | $1.7M ×6 |
| 2026-05-13 | HENDERSON MICHAEL THOMAS | Chief Executive Officer | Sold | 20,000 | $1.6M ×2 |
| 2026-08-05 | Dambkowski Carl | Chief Medical Officer | Sold | 5,500 | $737.9K |
| 2026-07-01 | Dambkowski Carl | Chief Medical Officer | Sold | 5,500 | $730.1K |
| 2026-06-03 | Dambkowski Carl | Chief Medical Officer | Sold | 5,500 | $432.9K |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q3 2026 | 1 | $10.7K | 79 | 0 | 1 | 0 | 0.0% |
| Q2 2026 | 293 | $9.1B | 67,569,005 | 116 | 83 | 66 | 2.2% |
| Q1 2026 | 228 | $6.8B | 79,061,221 | 44 | 103 | 54 | 1.7% |
| Q4 2025 | 208 | $5.4B | 71,327,318 | 46 | 86 | 47 | 0.8% |
| Q3 2025 | 175 | $2.4B | 60,721,751 | 25 | 59 | 56 | 0.7% |
| Q2 2025 | 183 | $2.6B | 57,837,640 | 36 | 54 | 64 | 2.1% |
| Q1 2025 | 171 | $2.3B | 61,509,553 | 37 | 49 | 55 | 1.0% |
| Q4 2024 | 158 | $2.6B | 57,873,775 | 30 | 52 | 40 | 0.2% |
| Q3 2024 | 139 | $3.3B | 56,121,928 | 27 | 44 | 46 | 0.5% |
| Q2 2024 | 138 | $2.1B | 54,180,445 | 32 | 46 | 41 | 0.0% |
| Q1 2024 | 139 | $3.5B | 53,211,755 | 61 | 52 | 19 | 0.1% |
| Q4 2023 | 85 | $1.2B | 41,859,159 | 20 | 32 | 9 | 0.0% |
| Q3 2023 | 73 | $848.7M | 40,111,239 | 73 | 0 | 0 | 0.0% |